The network for 'positive regulation of cytokine mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cytokine mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.

NameDescriptionProbabilityFunc Analog Organism
GRB2growth factor receptor-bound protein 20.998
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.986
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.971
LCKlymphocyte-specific protein tyrosine kinase0.950
FYNFYN oncogene related to SRC, FGR, YES0.947
SYKspleen tyrosine kinase0.889
HCKhemopoietic cell kinase0.581
EGFRepidermal growth factor receptor0.529
TBK1TANK-binding kinase 10.446
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.400
MYD88myeloid differentiation primary response gene (88)0.369
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.351
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.333
CASP8caspase 8, apoptosis-related cysteine peptidase0.296
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.280
GAS6growth arrest-specific 60.263
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.262
AXLAXL receptor tyrosine kinase0.255
PLCG1phospholipase C, gamma 10.251
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.197
TLR4toll-like receptor 40.186
NCK1NCK adaptor protein 10.180
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.179
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.173
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.167
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.139
IRAK1interleukin-1 receptor-associated kinase 10.127
BIRC3baculoviral IAP repeat containing 30.113
ZNF746zinc finger protein 7460.096
VAV1vav 1 guanine nucleotide exchange factor0.090
SPRR2Asmall proline-rich protein 2A0.087
LATlinker for activation of T cells0.085
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.078
PTPN22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.072
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.071
BLNKB-cell linker0.070
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.068
UBASH3Bubiquitin associated and SH3 domain containing B0.067
SH3KBP1SH3-domain kinase binding protein 10.062
TICAM1toll-like receptor adaptor molecule 10.060
RIPK2receptor-interacting serine-threonine kinase 20.057
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.056
TRAF3TNF receptor-associated factor 30.055
CASP10caspase 10, apoptosis-related cysteine peptidase0.054
IRAK2interleukin-1 receptor-associated kinase 20.053
PTPRJprotein tyrosine phosphatase, receptor type, J0.047
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.047
ITKIL2-inducible T-cell kinase0.046
GAB1GRB2-associated binding protein 10.046
IL1R1interleukin 1 receptor, type I0.045
TMEM173transmembrane protein 1730.039
IL1RAPinterleukin 1 receptor accessory protein0.037
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.034
CAV1caveolin 1, caveolae protein, 22kDa0.033
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.033
PIAS4protein inhibitor of activated STAT, 40.032
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.032
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.030
SHC1SHC (Src homology 2 domain containing) transforming protein 10.030
NOD2nucleotide-binding oligomerization domain containing 20.028
FZD1frizzled homolog 1 (Drosophila)0.025
GAS7growth arrest-specific 70.024
KLHL24kelch-like 24 (Drosophila)0.024
CXCR4chemokine (C-X-C motif) receptor 40.023
MUC1mucin 1, cell surface associated0.022
VAV2vav 2 guanine nucleotide exchange factor0.020
IRF3interferon regulatory factor 30.020
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.019
TENC1tensin like C1 domain containing phosphatase (tensin 2)0.019
PTPN1protein tyrosine phosphatase, non-receptor type 10.019
CD2APCD2-associated protein0.019
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.018
NOD1nucleotide-binding oligomerization domain containing 10.018
IRS1insulin receptor substrate 10.018
FASFas (TNF receptor superfamily, member 6)0.018
BTKBruton agammaglobulinemia tyrosine kinase0.017
WIPF1WAS/WASL interacting protein family, member 10.017
PLXNB1plexin B10.017
MED28mediator complex subunit 280.015
SH2B2SH2B adaptor protein 20.015
NELL2NEL-like 2 (chicken)0.014
CALCOCO2calcium binding and coiled-coil domain 20.014
PIAS2protein inhibitor of activated STAT, 20.014
FESfeline sarcoma oncogene0.013
MAVSmitochondrial antiviral signaling protein0.013
NR1D2nuclear receptor subfamily 1, group D, member 20.012
TRAF6TNF receptor-associated factor 60.012
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.012
CLIP1CAP-GLY domain containing linker protein 10.012
CFLARCASP8 and FADD-like apoptosis regulator0.012
PTPN11protein tyrosine phosphatase, non-receptor type 110.011
PELI3pellino homolog 3 (Drosophila)0.011
JAG2jagged 20.010
TNS4tensin 40.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism