The network for 'detection of muramyl dipeptide' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

detection of muramyl dipeptide

The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.

NameDescriptionProbabilityFunc Analog Organism
RIPK2receptor-interacting serine-threonine kinase 21.000
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta1.000
BIRC3baculoviral IAP repeat containing 30.851
PYCARDPYD and CARD domain containing0.839
PYDC2pyrin domain containing 20.825
GBP5guanylate binding protein 50.800
ANGangiogenin, ribonuclease, RNase A family, 50.796
NLRC4NLR family, CARD domain containing 40.508
BTN3A1butyrophilin, subfamily 3, member A10.470
NOD1nucleotide-binding oligomerization domain containing 10.355
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.328
TRAF3TNF receptor-associated factor 30.297
PILRApaired immunoglobin-like type 2 receptor alpha0.263
TP53BP1tumor protein p53 binding protein 10.228
HCP5HLA complex P50.178
FPR2formyl peptide receptor 20.169
MEFVMediterranean fever0.169
APOL3apolipoprotein L, 30.154
PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent, 1D0.107
KIF2Bkinesin family member 2B0.098
MAP3K14mitogen-activated protein kinase kinase kinase 140.090
GPX4glutathione peroxidase 4 (phospholipid hydroperoxidase)0.087
TERF2telomeric repeat binding factor 20.085
NLRP9NLR family, pyrin domain containing 90.074
TLR8toll-like receptor 80.073
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa0.069
RASAL3RAS protein activator like 30.068
HLA-Cmajor histocompatibility complex, class I, C0.065
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.057
OR52D1olfactory receptor, family 52, subfamily D, member 10.057
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.056
IFIH1interferon induced with helicase C domain 10.055
TRIM22tripartite motif containing 220.054
OR10A4olfactory receptor, family 10, subfamily A, member 40.054
TRAF1TNF receptor-associated factor 10.052
SYNGR2synaptogyrin 20.050
TREM1triggering receptor expressed on myeloid cells 10.049
HLA-Amajor histocompatibility complex, class I, A0.047
COPGcoatomer protein complex, subunit gamma0.047
NLRP4NLR family, pyrin domain containing 40.044
PSKH2protein serine kinase H20.044
NLRP11NLR family, pyrin domain containing 110.043
SLC26A9solute carrier family 26, member 90.043
ITGADintegrin, alpha D0.043
GBP4guanylate binding protein 40.043
FAM71Cfamily with sequence similarity 71, member C0.041
TXNDC3thioredoxin domain containing 3 (spermatozoa)0.041
MX2myxovirus (influenza virus) resistance 2 (mouse)0.040
C17orf87chromosome 17 open reading frame 870.039
RNF213ring finger protein 2130.039
C14orf183chromosome 14 open reading frame 1830.039
WFDC11WAP four-disulfide core domain 110.038
CCDC108coiled-coil domain containing 1080.036
MAVSmitochondrial antiviral signaling protein0.036
WFDC9WAP four-disulfide core domain 90.035
NLRP5NLR family, pyrin domain containing 50.035
TAS2R38taste receptor, type 2, member 380.033
SLC22A9solute carrier family 22 (organic anion transporter), member 90.032
IGFL1IGF-like family member 10.032
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.032
BATF2basic leucine zipper transcription factor, ATF-like 20.031
SPINK6serine peptidase inhibitor, Kazal type 60.031
FCARFc fragment of IgA, receptor for0.031
SLCO6A1solute carrier organic anion transporter family, member 6A10.030
TIMD4T-cell immunoglobulin and mucin domain containing 40.030
SLC16A6solute carrier family 16, member 6 (monocarboxylic acid transporter 7)0.028
FAM169Bfamily with sequence similarity 169, member B0.028
ATP6V0D1ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d10.028
ACMSDaminocarboxymuconate semialdehyde decarboxylase0.028
ADAM21ADAM metallopeptidase domain 210.027
PARP12poly (ADP-ribose) polymerase family, member 120.027
KRTAP11-1keratin associated protein 11-10.027
NUP210Lnucleoporin 210kDa-like0.027
DEFB119defensin, beta 1190.027
CIB4calcium and integrin binding family member 40.026
GPRC6AG protein-coupled receptor, family C, group 6, member A0.026
CCDC54coiled-coil domain containing 540.026
XAGE3X antigen family, member 30.026
GPR84G protein-coupled receptor 840.025
GPR112G protein-coupled receptor 1120.025
UCMAupper zone of growth plate and cartilage matrix associated0.025
SPATA16spermatogenesis associated 160.025
KRT82keratin 820.024
GSDMCgasdermin C0.024
CSF2RAcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)0.024
IL17Finterleukin 17F0.024
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.024
C11orf53chromosome 11 open reading frame 530.024
C3orf22chromosome 3 open reading frame 220.024
KRTAP7-1keratin associated protein 7-1 (gene/pseudogene)0.023
TFAP2Dtranscription factor AP-2 delta (activating enhancer binding protein 2 delta)0.023
MRGPRX2MAS-related GPR, member X20.023
DNAH8dynein, axonemal, heavy chain 80.023
NLRP8NLR family, pyrin domain containing 80.023
ACPPacid phosphatase, prostate0.023
SIRPB1signal-regulatory protein beta 10.022
TEX101testis expressed 1010.022
FAM186Bfamily with sequence similarity 186, member B0.022
SAMD9Lsterile alpha motif domain containing 9-like0.022
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism