The network for 'endothelial cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endothelial cell migration

The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.

NameDescriptionProbabilityFunc Analog Organism
FN1fibronectin 11.000
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide1.000
EGFRepidermal growth factor receptor1.000
VEGFAvascular endothelial growth factor A0.998
FGFR2fibroblast growth factor receptor 20.997
TEKTEK tyrosine kinase, endothelial0.996
SFNstratifin0.996
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.996
YAP1Yes-associated protein 10.994
JAG1jagged 10.994
S100BS100 calcium binding protein B0.986
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.984
S100A6S100 calcium binding protein A60.978
NRP1neuropilin 10.978
S100A11S100 calcium binding protein A110.977
LATlinker for activation of T cells0.973
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.967
JUNjun proto-oncogene0.963
PTPN1protein tyrosine phosphatase, non-receptor type 10.958
FOSFBJ murine osteosarcoma viral oncogene homolog0.956
CAV1caveolin 1, caveolae protein, 22kDa0.953
FGF1fibroblast growth factor 1 (acidic)0.952
ZYXzyxin0.950
RARAretinoic acid receptor, alpha0.942
ANXA1annexin A10.940
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.937
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.932
NOTCH1notch 10.924
FYNFYN oncogene related to SRC, FGR, YES0.924
THBS1thrombospondin 10.922
POU5F1POU class 5 homeobox 10.918
NR4A2nuclear receptor subfamily 4, group A, member 20.916
BMPR1Abone morphogenetic protein receptor, type IA0.909
ENGendoglin0.906
FKBP1AFK506 binding protein 1A, 12kDa0.893
FGAfibrinogen alpha chain0.891
KLF4Kruppel-like factor 4 (gut)0.888
S100A8S100 calcium binding protein A80.887
FBLN1fibulin 10.887
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.860
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.858
TGFB1transforming growth factor, beta 10.851
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.840
EGR1early growth response 10.832
HSPB8heat shock 22kDa protein 80.830
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.827
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.823
FLNAfilamin A, alpha0.819
EMP3epithelial membrane protein 30.813
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.813
NR4A1nuclear receptor subfamily 4, group A, member 10.797
SMAD3SMAD family member 30.789
BCAR1breast cancer anti-estrogen resistance 10.785
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.784
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.778
GRB7growth factor receptor-bound protein 70.772
S100A14S100 calcium binding protein A140.771
TPM4tropomyosin 40.771
ANXA2annexin A20.769
CTGFconnective tissue growth factor0.766
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.764
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.760
EGR3early growth response 30.748
CYR61cysteine-rich, angiogenic inducer, 610.745
CRYABcrystallin, alpha B0.736
FGFR1fibroblast growth factor receptor 10.734
S100A4S100 calcium binding protein A40.732
S100A1S100 calcium binding protein A10.696
TAL1T-cell acute lymphocytic leukemia 10.695
PRKCAprotein kinase C, alpha0.694
TIMP1TIMP metallopeptidase inhibitor 10.687
BMP2bone morphogenetic protein 20.684
LMNAlamin A/C0.676
MAP3K3mitogen-activated protein kinase kinase kinase 30.675
PPLperiplakin0.671
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.665
KLK10kallikrein-related peptidase 100.651
NOTCH3notch 30.648
NOSTRINnitric oxide synthase trafficker0.644
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.641
NR4A3nuclear receptor subfamily 4, group A, member 30.611
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.601
VIMvimentin0.574
S100A16S100 calcium binding protein A160.565
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.557
SH3KBP1SH3-domain kinase binding protein 10.553
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.552
NCOR2nuclear receptor corepressor 20.532
S100A9S100 calcium binding protein A90.519
TIMP3TIMP metallopeptidase inhibitor 30.506
PDGFCplatelet derived growth factor C0.505
KLF6Kruppel-like factor 60.499
IER2immediate early response 20.494
DUSP1dual specificity phosphatase 10.483
FSTL1follistatin-like 10.477
A2Malpha-2-macroglobulin0.468
VEGFCvascular endothelial growth factor C0.458
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.457
JUNBjun B proto-oncogene0.455
NTRK2neurotrophic tyrosine kinase, receptor, type 20.445
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
efnb2aephrin B2a0.840
notch3notch homolog 30.727
dlcdeltaC0.626
robo3roundabout homolog 30.541
kdrlkinase insert domain receptor like0.527
dll4delta-like 4 (Drosophila)0.500
tbx2bT-box 2b0.488
vegfaavascular endothelial growth factor Aa0.450
pitx3paired-like homeodomain transcription factor 30.435
cdh5cadherin 50.360
itgb1b.2integrin, beta 1b.20.336
vegfcvascular endothelial growth factor c0.333
ccm2cerebral cavernous malformation 20.308
si:ch211-212m21.5si:ch211-212m21.50.294
etv2ets variant gene 20.234
aox3aldehyde oxidase 30.228
irx5airoquois homeobox protein 5a0.222
gata2aGATA-binding protein 2a0.216
mmp2matrix metalloproteinase 20.174
unc5bunc-5 homolog B (C. elegans)0.170
wnt11rwingless-type MMTV integration site family, member 11, related0.166
plcg1phospholipase C, gamma 10.159
dlbdeltaB0.141
tal1T-cell acute lymphocytic leukemia 10.138
fzd7afrizzled homolog 7a0.136
tgfbitransforming growth factor, beta-induced0.133
spry4sprouty (Drosophila) homolog 40.131
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.131
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.130
cdh23cadherin-like 230.123
dlddeltaD0.122
ccbe1collagen and calcium binding EGF domains 10.120
fgfr3fibroblast growth factor receptor 30.115
gata3GATA-binding protein 30.108
pxnpaxillin0.107
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.103
eml2echinoderm microtubule associated protein like 20.095
fabp11afatty acid binding protein 11a0.095
nrp2bneuropilin 2b0.094
jag1ajagged 1a0.094
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.094
pak2ap21 (CDKN1A)-activated kinase 2a0.090
jag2jagged 20.089
si:ch73-60e21.1si:ch73-60e21.10.088
sulf1sulfatase 10.088
nrarpanotch-regulated ankyrin repeat protein a0.081
frem1aFras1 related extracellular matrix 1a0.077
bmp2abone morphogenetic protein 2a0.077
bmp2bbone morphogenetic protein 2b0.073
myf5myogenic factor 50.064
wtipWilms tumor 1 interacting protein0.063
alcamaactivated leukocyte cell adhesion molecule a0.061
mcambmelanoma cell adhesion molecule b0.059
itgb3bintegrin beta 3b0.059
myod1myogenic differentiation 10.057
krit1KRIT1, ankyrin repeat containing0.057
lmx1b.1LIM homeobox transcription factor 1, beta 10.057
skianuclear oncoprotein skia0.056
klf2aKruppel-like factor 2a0.054
crabp2bcellular retinoic acid binding protein 2, b0.054
rargaretinoic acid receptor gamma a0.054
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.053
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.053
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.051
gyltl1bglycosyltransferase-like 1b0.050
sox7SRY-box containing gene 70.050
sox10SRY-box containing gene 100.050
tie2endothelium-specific receptor tyrosine kinase 20.049
metmet proto-oncogene (hepatocyte growth factor receptor)0.048
entpd3ectonucleoside triphosphate diphosphohydrolase 30.045
LOC100003514protein kinase C alpha type-like0.044
bmperBMP binding endothelial regulator0.044
hsp47heat shock protein 470.044
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.043
ascl1aachaete-scute complex-like 1a (Drosophila)0.043
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.043
hey1hairy/enhancer-of-split related with YRPW motif 10.043
tie1endothelium-specific receptor tyrosine kinase 10.042
mapk4mitogen-activated protein kinase 40.042
vcanaversican a0.041
hey2hairy/enhancer-of-split related with YRPW motif 20.041
acvrl1activin A receptor type II-like 10.041
tp63tumor protein p630.040
sdc2syndecan 20.040
tfectranscription factor EC0.039
tgfb1atransforming growth factor, beta 1a0.039
ctrb1chymotrypsinogen B10.038
smad9MAD homolog 9 (Drosophila)0.037
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.037
fbn2bfibrillin 2b0.037
msnamoesin a0.036
ntn1anetrin 1a0.036
tagln2transgelin 20.036
sox11aSRY-box containing gene 11a0.034
flt4fms-related tyrosine kinase 40.034
pax7apaired box gene 7a0.034
pax8paired box gene 80.033
dccdeleted in colorectal carcinoma0.033
sardhsarcosine dehydrogenase0.032
itgb1b.1integrin, beta 1b.10.032
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Efnb2ephrin B20.994
Fgfr1fibroblast growth factor receptor 10.957
Pax2paired box gene 20.919
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.910
Vegfavascular endothelial growth factor A0.905
Nrp1neuropilin 10.900
Flt4FMS-like tyrosine kinase 40.876
Foxc1forkhead box C10.870
Ptk2PTK2 protein tyrosine kinase 20.864
Ephb2Eph receptor B20.832
Jag1jagged 10.817
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.810
Epha4Eph receptor A40.735
Nos3nitric oxide synthase 3, endothelial cell0.727
Engendoglin0.711
Apoeapolipoprotein E0.679
Kdrkinase insert domain protein receptor0.660
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.622
Acvr1activin A receptor, type 10.604
Itgb1integrin beta 1 (fibronectin receptor beta)0.564
Nognoggin0.558
Pax8paired box gene 80.540
Col4a2collagen, type IV, alpha 20.524
Slit3slit homolog 3 (Drosophila)0.491
Gab1growth factor receptor bound protein 2-associated protein 10.485
Fgfr2fibroblast growth factor receptor 20.467
Flt1FMS-like tyrosine kinase 10.466
Ptpn11protein tyrosine phosphatase, non-receptor type 110.463
Tgfb2transforming growth factor, beta 20.457
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.454
Itgb3integrin beta 30.441
Gata6GATA binding protein 60.438
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.420
Otx2orthodenticle homolog 2 (Drosophila)0.410
Ptprbprotein tyrosine phosphatase, receptor type, B0.404
Cxcl12chemokine (C-X-C motif) ligand 120.395
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.390
Cdh5cadherin 50.386
Psen1presenilin 10.369
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.361
Pax3paired box gene 30.358
Hey2hairy/enhancer-of-split related with YRPW motif 20.351
Col4a1collagen, type IV, alpha 10.339
Rag1recombination activating gene 10.333
Ephb3Eph receptor B30.333
Dll1delta-like 1 (Drosophila)0.328
Nr2f1nuclear receptor subfamily 2, group F, member 10.323
Kitkit oncogene0.299
Grb2growth factor receptor bound protein 20.289
Fgf10fibroblast growth factor 100.286
Tspan9tetraspanin 90.285
Tgfb1transforming growth factor, beta 10.284
Dab1disabled homolog 1 (Drosophila)0.281
Fzd1frizzled homolog 1 (Drosophila)0.272
Notch1Notch gene homolog 1 (Drosophila)0.269
Plxna1plexin A10.263
Csf1colony stimulating factor 1 (macrophage)0.261
SrcRous sarcoma oncogene0.260
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.256
Notch2Notch gene homolog 2 (Drosophila)0.246
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.240
Sox7SRY-box containing gene 70.235
Efnb1ephrin B10.233
Acvrl1activin A receptor, type II-like 10.231
Smad3MAD homolog 3 (Drosophila)0.227
Cyr61cysteine rich protein 610.214
Notch3Notch gene homolog 3 (Drosophila)0.211
Wwtr1WW domain containing transcription regulator 10.209
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.207
Irs1insulin receptor substrate 10.201
FynFyn proto-oncogene0.200
Actn1actinin, alpha 10.199
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.197
Ntf3neurotrophin 30.193
Mmp15matrix metallopeptidase 150.193
Apcadenomatosis polyposis coli0.193
Dock1dedicator of cytokinesis 10.190
Hif1ahypoxia inducible factor 1, alpha subunit0.189
Gli3GLI-Kruppel family member GLI30.185
Cdkn2acyclin-dependent kinase inhibitor 2A0.185
Smad6MAD homolog 6 (Drosophila)0.184
Vangl2vang-like 2 (van gogh, Drosophila)0.176
Efsembryonal Fyn-associated substrate0.172
Ctnnb1catenin (cadherin associated protein), beta 10.170
Apoa1apolipoprotein A-I0.168
Npas1neuronal PAS domain protein 10.168
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.168
Loxlysyl oxidase0.166
Fjx1four jointed box 1 (Drosophila)0.166
Gdf11growth differentiation factor 110.165
Hspg2perlecan (heparan sulfate proteoglycan 2)0.164
Tgfbr2transforming growth factor, beta receptor II0.164
Lrp1low density lipoprotein receptor-related protein 10.163
Pou3f3POU domain, class 3, transcription factor 30.158
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.155
Ptenphosphatase and tensin homolog0.154
Esamendothelial cell-specific adhesion molecule0.152
Gli2GLI-Kruppel family member GLI20.150
RgnefRho-guanine nucleotide exchange factor0.148
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.144
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Btg2BTG family, member 20.014
Junbjun B proto-oncogene0.014
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism