The network for 'vesicle docking involved in exocytosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

vesicle docking involved in exocytosis

The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.

NameDescriptionProbabilityFunc Analog Organism
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.955
MON1BMON1 homolog B (yeast)0.870
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.625
SNAP25synaptosomal-associated protein, 25kDa0.365
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.242
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.196
RABIFRAB interacting factor0.146
SNAP23synaptosomal-associated protein, 23kDa0.140
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.121
RAB10RAB10, member RAS oncogene family0.121
RAB8ARAB8A, member RAS oncogene family0.082
RAB27ARAB27A, member RAS oncogene family0.059
OCRLoculocerebrorenal syndrome of Lowe0.055
RAB27BRAB27B, member RAS oncogene family0.050
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.047
VAMP8vesicle-associated membrane protein 8 (endobrevin)0.046
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.043
CLTBclathrin, light chain B0.036
STX5syntaxin 50.035
GNA13guanine nucleotide binding protein (G protein), alpha 130.028
NRBP1nuclear receptor binding protein 10.025
NSFN-ethylmaleimide-sensitive factor0.024
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.023
CPLX1complexin 10.020
KCTD5potassium channel tetramerisation domain containing 50.018
STX1Asyntaxin 1A (brain)0.017
MSNmoesin0.017
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.017
TMOD3tropomodulin 3 (ubiquitous)0.016
SRPRsignal recognition particle receptor (docking protein)0.016
GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 30.016
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)0.016
TFRCtransferrin receptor (p90, CD71)0.016
STXBP1syntaxin binding protein 10.016
ARL3ADP-ribosylation factor-like 30.016
C12orf44chromosome 12 open reading frame 440.015
CAPZA2capping protein (actin filament) muscle Z-line, alpha 20.015
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.014
PCYT1Aphosphate cytidylyltransferase 1, choline, alpha0.013
ARF6ADP-ribosylation factor 60.013
TRDMT1tRNA aspartic acid methyltransferase 10.013
PRRT2proline-rich transmembrane protein 20.013
ZFAND6zinc finger, AN1-type domain 60.013
CREB3cAMP responsive element binding protein 30.013
C20orf24chromosome 20 open reading frame 240.012
TLR1toll-like receptor 10.012
FAM190Bfamily with sequence similarity 190, member B0.012
VPS16vacuolar protein sorting 16 homolog (S. cerevisiae)0.012
STK4serine/threonine kinase 40.011
RAB6ARAB6A, member RAS oncogene family0.011
SYT1synaptotagmin I0.011
WDR47WD repeat domain 470.011
C11orf24chromosome 11 open reading frame 240.011
ZFYVE16zinc finger, FYVE domain containing 160.011
NSFL1CNSFL1 (p97) cofactor (p47)0.011
GPKOWG patch domain and KOW motifs0.011
SELSselenoprotein S0.010
RNF25ring finger protein 250.010
C1orf144chromosome 1 open reading frame 1440.010
SSFA2sperm specific antigen 20.010
CD58CD58 molecule0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Snap25synaptosomal-associated protein 250.838
Vamp2vesicle-associated membrane protein 20.666
Prnpprion protein0.412
Stxbp1syntaxin binding protein 10.411
Htthuntingtin0.161
Stx1asyntaxin 1A (brain)0.142
Rusc1RUN and SH3 domain containing 10.094
Stxbp5syntaxin binding protein 5 (tomosyn)0.087
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.078
Syt2synaptotagmin II0.063
Dnm1dynamin 10.049
Atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.044
Rab24RAB24, member RAS oncogene family0.036
Uchl1ubiquitin carboxy-terminal hydrolase L10.036
Appamyloid beta (A4) precursor protein0.033
Tbk1TANK-binding kinase 10.032
Pnrc2proline-rich nuclear receptor coactivator 20.031
Nptnneuroplastin0.026
Clstn1calsyntenin 10.022
L1camL1 cell adhesion molecule0.022
Kif5ckinesin family member 5C0.022
Snap23synaptosomal-associated protein 230.019
Dync1i2dynein cytoplasmic 1 intermediate chain 20.019
Rab5aRAB5A, member RAS oncogene family0.017
Tmem123transmembrane protein 1230.015
Dnase1l1deoxyribonuclease 1-like 10.015
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.014
Bsnbassoon0.014
Fam50afamily with sequence similarity 50, member A0.014
Kifc2kinesin family member C20.014
Stx7syntaxin 70.013
Wdr1WD repeat domain 10.013
Gosr1golgi SNAP receptor complex member 10.013
Aplp2amyloid beta (A4) precursor-like protein 20.012
Sparcl1SPARC-like 10.012
Lamp2lysosomal-associated membrane protein 20.012
Sos2son of sevenless homolog 2 (Drosophila)0.012
Ppm1mprotein phosphatase 1M0.012
Lsamplimbic system-associated membrane protein0.012
Vps4bvacuolar protein sorting 4b (yeast)0.012
Chukconserved helix-loop-helix ubiquitous kinase0.011
Spna2spectrin alpha 20.011
Chmp5chromatin modifying protein 50.011
Arpc4actin related protein 2/3 complex, subunit 40.011
Syf2SYF2 homolog, RNA splicing factor (S. cerevisiae)0.010
Cluclusterin0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Stxbp1syntaxin binding protein 10.934
Snap25synaptosomal-associated protein 250.593
Stx1asyntaxin 1A (brain)0.218
Vamp2vesicle-associated membrane protein 20.111
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.111
Prkcbprotein kinase C, beta0.070
Sncbsynuclein, beta0.050
Gosr2golgi SNAP receptor complex member 20.045
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.044
Sypsynaptophysin0.041
RGD1303130kidney predominant protein NCU-G10.036
Necap2NECAP endocytosis associated 20.030
Pdzd4PDZ domain containing 40.030
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.028
Cacnb3calcium channel, voltage-dependent, beta 3 subunit0.027
Srgnserglycin0.026
Scamp2secretory carrier membrane protein 20.026
Rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.025
Rhbdl1rhomboid, veinlet-like 1 (Drosophila)0.024
Ndrg4N-myc downstream regulated gene 40.024
Maptmicrotubule-associated protein tau0.024
Cd53Cd53 molecule0.024
Cplx1complexin 10.023
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.023
Prr13proline rich 130.022
Inainternexin neuronal intermediate filament protein, alpha0.022
MaddMAP-kinase activating death domain0.021
L1camL1 cell adhesion molecule0.021
Tmem97transmembrane protein 970.019
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.019
Fermt3fermitin family homolog 3 (Drosophila)0.019
Olfm1olfactomedin 10.018
Camk2bcalcium/calmodulin-dependent protein kinase II beta0.017
Stxbp5syntaxin binding protein 5 (tomosyn)0.017
Arfrp1ADP-ribosylation factor related protein 10.017
Map1bmicrotubule-associated protein 1B0.016
Crmp1collapsin response mediator protein 10.016
Rnf181ring finger protein 1810.016
Lrrc59leucine rich repeat containing 590.015
Surf4surfeit 40.015
Slfn2schlafen 20.015
Gm2aGM2 ganglioside activator0.015
Dlgap3discs, large (Drosophila) homolog-associated protein 30.015
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.014
Arhgap25Rho GTPase activating protein 250.014
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.014
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.014
Ifi35interferon-induced protein 350.014
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.014
Rnf112ring finger protein 1120.014
Wsb2WD repeat and SOCS box-containing 20.014
Copz1coatomer protein complex, subunit zeta 10.014
Hk1hexokinase 10.013
Ctxn1cortexin 10.013
Apcadenomatous polyposis coli0.013
Stk38serine/threonine kinase 380.013
Nrxn1neurexin 10.013
Syn2synapsin II0.012
S100a9S100 calcium binding protein A90.012
Fgfr1op2FGFR1 oncogene partner 20.012
Dnm1dynamin 10.011
Tex261testis expressed 2610.011
Gabbr2gamma-aminobutyric acid (GABA) B receptor 20.011
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.011
Anxa4annexin A40.011
Exoc7exocyst complex component 70.011
Smap2small ArfGAP20.010
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.010
NsfN-ethylmaleimide-sensitive factor0.010
Gorasp2golgi reassembly stacking protein 20.010
Rnpeparginyl aminopeptidase (aminopeptidase B)0.010
Dlgap4discs, large homolog-associated protein 4 (Drosophila)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SEC1Sec1p0.992
SEC15Sec15p0.966
SEC10Sec10p0.956
SEC6Sec6p0.951
SEC9Sec9p0.929
SEC8Sec8p0.918
SEC5Sec5p0.884
EXO84Exo84p0.839
EXO70Exo70p0.819
SRO7Sro7p0.624
MSO1Mso1p0.618
SEC2Sec2p0.526
SSO1Sso1p0.178
YPT1Ypt1p0.170
SEC3Sec3p0.168
PEP5Pep5p0.052
SEC4Sec4p0.051
VPS3Vps3p0.038
SFT1Sft1p0.031
SNC2Snc2p0.020
SRD1Srd1p0.013
VPS45Vps45p0.013
LEU2Leu2p0.012
TLG1Tlg1p0.011
YOL038C-Ahypothetical protein0.011
SEC18Sec18p0.011
YLR162Whypothetical protein0.011
YLR264C-Ahypothetical protein0.011
ARP10Arp10p0.011
GDI1Gdi1p0.010
SPL2Spl2p0.010