The network for 'blastoderm segmentation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blastoderm segmentation

The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.

NameDescriptionProbabilityFunc Analog Organism
RING1ring finger protein 10.995
PCGF2polycomb group ring finger 20.981
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.980
USP11ubiquitin specific peptidase 110.980
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.976
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.960
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.936
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.927
SNAP25synaptosomal-associated protein, 25kDa0.918
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.892
CCNT1cyclin T10.886
EGFRepidermal growth factor receptor0.862
EIF2C2eukaryotic translation initiation factor 2C, 20.851
RBL2retinoblastoma-like 2 (p130)0.846
CHD8chromodomain helicase DNA binding protein 80.819
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.813
GDAguanine deaminase0.775
PTPN1protein tyrosine phosphatase, non-receptor type 10.755
SUFUsuppressor of fused homolog (Drosophila)0.748
NXF1nuclear RNA export factor 10.743
INSRinsulin receptor0.736
OCRLoculocerebrorenal syndrome of Lowe0.733
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.726
IRS1insulin receptor substrate 10.726
SMAD2SMAD family member 20.701
CBX8chromobox homolog 80.689
CUL2cullin 20.683
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.674
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.651
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.624
EIF2C1eukaryotic translation initiation factor 2C, 10.613
EDC3enhancer of mRNA decapping 3 homolog (S. cerevisiae)0.610
RBX1ring-box 1, E3 ubiquitin protein ligase0.569
FGFR1fibroblast growth factor receptor 10.556
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.554
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.532
YAP1Yes-associated protein 10.521
SOCS1suppressor of cytokine signaling 10.520
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.495
BMP1bone morphogenetic protein 10.492
KEAP1kelch-like ECH-associated protein 10.490
PCGF3polycomb group ring finger 30.489
CLNS1Achloride channel, nucleotide-sensitive, 1A0.484
MEOX2mesenchyme homeobox 20.479
VHLvon Hippel-Lindau tumor suppressor0.477
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)0.475
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.470
LIN9lin-9 homolog (C. elegans)0.459
TNRC6Atrinucleotide repeat containing 6A0.458
IL4Rinterleukin 4 receptor0.450
BMI1BMI1 polycomb ring finger oncogene0.446
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.440
RFWD2ring finger and WD repeat domain 20.439
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.425
CBX4chromobox homolog 40.423
CSNK2A2casein kinase 2, alpha prime polypeptide0.422
SCHIP1schwannomin interacting protein 10.413
CD44CD44 molecule (Indian blood group)0.412
RAB5ARAB5A, member RAS oncogene family0.409
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.408
PPARAperoxisome proliferator-activated receptor alpha0.406
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.401
TNRC6Btrinucleotide repeat containing 6B0.401
SPENspen homolog, transcriptional regulator (Drosophila)0.401
CHD7chromodomain helicase DNA binding protein 70.391
NFE2L2nuclear factor (erythroid-derived 2)-like 20.381
CDC37cell division cycle 37 homolog (S. cerevisiae)0.372
PICALMphosphatidylinositol binding clathrin assembly protein0.367
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.365
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.362
TNRC6Ctrinucleotide repeat containing 6C0.358
CDC27cell division cycle 27 homolog (S. cerevisiae)0.358
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.356
ADAM17ADAM metallopeptidase domain 170.354
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.354
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.352
SFPQsplicing factor proline/glutamine-rich0.346
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.340
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.335
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.328
NOTCH1notch 10.327
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.327
PRKCIprotein kinase C, iota0.322
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.319
EIF2C4eukaryotic translation initiation factor 2C, 40.316
METmet proto-oncogene (hepatocyte growth factor receptor)0.315
YBX1Y box binding protein 10.312
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.307
UPF3BUPF3 regulator of nonsense transcripts homolog B (yeast)0.305
TRA2Btransformer 2 beta homolog (Drosophila)0.304
CUL1cullin 10.303
SOX10SRY (sex determining region Y)-box 100.301
SMAD1SMAD family member 10.301
DLG4discs, large homolog 4 (Drosophila)0.299
MAZMYC-associated zinc finger protein (purine-binding transcription factor)0.294
RNF2ring finger protein 20.292
WDR5WD repeat domain 50.288
MAP2K1mitogen-activated protein kinase kinase 10.285
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mpk-1Protein MPK-10.086
vav-1Protein VAV-10.070
par-5Protein PAR-50.068
wrm-1Protein WRM-10.060
ina-1Protein INA-10.055
lsy-22Protein LSY-220.042
pha-4Protein PHA-40.042
egl-18Protein EGL-180.041
lin-45Protein LIN-450.033
nhr-67Protein NHR-670.029
fem-1Protein FEM-10.029
let-60Protein LET-600.025
unc-62Protein UNC-620.021
ceh-20Protein CEH-200.021
goa-1Protein GOA-10.019
elt-6Protein ELT-60.018
snr-3Protein SNR-30.018
ajm-1Protein AJM-10.016
tra-1Protein TRA-10.015
elc-1Protein ELC-10.015
C50B8.1Protein C50B8.10.014
glh-4Protein GLH-40.014
egl-46Protein EGL-460.014
hlh-30Protein HLH-300.013
pgl-1Protein PGL-10.013
ucr-2.3Protein UCR-2.30.012
cec-1Protein CEC-10.012
pry-1Protein PRY-10.012
rho-1Protein RHO-10.012
xpo-2Protein XPO-20.012
pqn-51Protein PQN-510.011
zip-7Protein ZIP-70.011
hnd-1Protein HND-10.011
tbb-1Protein TBB-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.401
ca15bcarbonic anhydrase XV b0.345
ndr2nodal-related 20.217
oepone-eyed pinhead0.093
tbx16T-box gene 160.092
cdx4caudal type homeo box transcription factor 40.085
smosmoothened homolog (Drosophila)0.083
col8a1acollagen, type VIII, alpha 1a0.083
nrp1aneuropilin 1a0.075
nanos3nanos homolog 30.071
wnt11wingless-type MMTV integration site family, member 110.069
pax7apaired box gene 7a0.068
mef2cbmyocyte enhancer factor 2cb0.063
orgoogenesis-related gene0.062
brca2breast cancer 2, early onset0.059
mibmind bomb0.058
pou5f1POU domain, class 5, transcription factor 10.054
wnt2bbwingless-type MMTV integration site family, member 2Bb0.054
sox32SRY-box containing gene 320.050
kitakit receptor a0.046
vasavasa homolog0.043
fanclFanconi anemia, complementation group L0.042
flhfloating head0.036
tbx20T-box 200.033
wnt4awingless-type MMTV integration site family, member 4a0.032
lef1lymphocyte enhancer binding factor 10.031
plod1aprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a0.031
ntlano tail a0.029
e2f5E2F transcription factor 50.029
jak1Janus kinase 10.027
smad5MAD homolog 5 (Drosophila)0.027
alcambactivated leukocyte cell adhesion molecule b0.025
tp53tumor protein p530.024
nrp1bneuropilin 1b0.023
axin1axin 10.023
il7rinterleukin 7 receptor0.022
rap1bRAS related protein 1b0.022
mef2camyocyte enhancer factor 2ca0.022
arnt2aryl hydrocarbon receptor nuclear translocator 20.021
bnc2basonuclin 20.021
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.021
hoxa13bhomeo box A13b0.020
tshbthyroid stimulating hormone, beta subunit0.020
piwil1piwi-like 1 (Drosophila)0.018
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.018
ros1v-ros UR2 sarcoma virus oncogene homolog 1 (avian)0.017
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.017
slc25a37solute carrier family 25, member 370.017
piwil2piwi-like 2 (Drosophila)0.017
pcdh18bprotocadherin 18b0.016
tdrd1tudor domain containing 10.016
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.016
supt6hsuppressor of Ty 6 homolog0.016
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.015
wnt2bawingless-type MMTV integration site family, member 2Ba0.015
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.015
ptpraprotein tyrosine phosphatase, receptor type, A0.015
sema3aasemaphorin 3aa0.015
brd2abromodomain-containing 2a0.015
odz4odd Oz/ten-m homolog 40.015
hk1hexokinase 10.014
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.014
smyhc1slow myosin heavy chain 10.014
csnk1a1casein kinase 1, alpha 10.014
elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.014
sema3esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E0.014
mtpmicrosomal triglyceride transfer protein0.014
hoxc11ahomeo box C11a0.014
nrp2aneuropilin 2a0.014
tpm4tropomyosin 40.013
nudt9nudix (nucleoside diphosphate linked moiety X)-type motif 90.013
vaspvasodilator-stimulated phosphoprotein0.013
ccnb1cyclin B10.013
acvr1lactivin A receptor, type I like0.013
neurog1neurogenin 10.012
shhasonic hedgehog a0.012
ef1ETS-related factor10.012
eif2c4eukaryotic translation initiation factor 2C, 40.012
sox9bSRY-box containing gene 9b0.012
trpm7transient receptor potential cation channel, subfamily M, member 70.011
dccdeleted in colorectal carcinoma0.011
mecomMDS1 and EVI1 complex locus0.011
hoxd10ahomeo box D10a0.011
elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.011
igfbp3insulin-like growth factor binding protein 30.011
bmpr1bbbone morphogenetic protein receptor, type 1bb0.011
bonbonnie and clyde0.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
aPKCatypical protein kinase C0.999
cicubitus interruptus0.996
ftz-f1ftz transcription factor 10.996
slmbsupernumerary limbs0.983
par-6CG5884 gene product from transcript CG5884-RA0.980
BicDBicaudal D0.980
phlpole hole0.977
eyaeyes absent0.966
gcmglial cells missing0.945
Hel25EHelicase at 25E0.945
magomago nashi0.943
gbbglass bottom boat0.933
traltrailer hitch0.932
bratbrain tumor0.904
Dcp1Decapping protein 10.904
orboo18 RNA-binding protein0.880
ksrkinase suppressor of ras0.871
DadDaughters against dpp0.861
TER94CG2331 gene product from transcript CG2331-RA0.857
Ras85DRas oncogene at 85D0.848
opaodd paired0.843
CG6854CG6854 gene product from transcript CG6854-RC0.838
fs(1)M3female sterile (1) M30.819
slp1sloppy paired 10.817
sec5CG8843 gene product from transcript CG8843-RA0.813
me31Bmaternal expression at 31B0.795
SosSon of sevenless0.791
Pi3K92ECG4141 gene product from transcript CG4141-RB0.787
Dhc64CDynein heavy chain 64C0.785
par-1CG8201 gene product from transcript CG8201-RA0.782
Myd88CG2078 gene product from transcript CG2078-RA0.752
Rac1CG2248 gene product from transcript CG2248-RA0.729
salmspalt major0.725
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.725
ovoCG6824 gene product from transcript CG6824-RE0.687
nkdnaked cuticle0.665
JIL-1CG6297 gene product from transcript CG6297-RA0.607
grhgrainy head0.598
aopanterior open0.591
DlicDynein light intermediate chain0.550
Apc2Adenomatous polyposis coli tumor suppressor homolog 20.532
pdm2POU domain protein 20.529
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.999
Apcadenomatosis polyposis coli0.990
Bmpr1abone morphogenetic protein receptor, type 1A0.884
Smad4MAD homolog 4 (Drosophila)0.876
Gsk3bglycogen synthase kinase 3 beta0.849
Gli2GLI-Kruppel family member GLI20.746
Fgf10fibroblast growth factor 100.731
Gata4GATA binding protein 40.724
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.700
Pcgf2polycomb group ring finger 20.686
Pax2paired box gene 20.668
Shhsonic hedgehog0.655
Gli3GLI-Kruppel family member GLI30.655
Ccnd1cyclin D10.648
Nf1neurofibromatosis 10.641
Smad3MAD homolog 3 (Drosophila)0.613
Stat3signal transducer and activator of transcription 30.562
Lhx1LIM homeobox protein 10.542
Hoxd13homeobox D130.513
Fgf8fibroblast growth factor 80.497
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.479
Wnt5awingless-related MMTV integration site 5A0.462
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.456
Smad1MAD homolog 1 (Drosophila)0.441
Trp53transformation related protein 530.440
Fgfr1fibroblast growth factor receptor 10.395
Fzd1frizzled homolog 1 (Drosophila)0.376
Stat5bsignal transducer and activator of transcription 5B0.371
Pitx2paired-like homeodomain transcription factor 20.369
Notch1Notch gene homolog 1 (Drosophila)0.367
Egfrepidermal growth factor receptor0.310
Plxna1plexin A10.285
Foxp3forkhead box P30.260
Gata6GATA binding protein 60.244
Itgb1integrin beta 1 (fibronectin receptor beta)0.243
Sox9SRY-box containing gene 90.241
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.238
Rargretinoic acid receptor, gamma0.218
Retret proto-oncogene0.205
Emx2empty spiracles homolog 2 (Drosophila)0.194
Rararetinoic acid receptor, alpha0.180
Plcg1phospholipase C, gamma 10.179
Stat5asignal transducer and activator of transcription 5A0.179
Zeb1zinc finger E-box binding homeobox 10.176
Otx2orthodenticle homolog 2 (Drosophila)0.173
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.172
Arandrogen receptor0.169
Fzd7frizzled homolog 7 (Drosophila)0.152
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.146
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.145
Fgfr2fibroblast growth factor receptor 20.145
Rarbretinoic acid receptor, beta0.142
Foxh1forkhead box H10.138
Fgf9fibroblast growth factor 90.136
Inpp5dinositol polyphosphate-5-phosphatase D0.135
Foxf1aforkhead box F1a0.134
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.132
Smosmoothened homolog (Drosophila)0.125
Ncoa2nuclear receptor coactivator 20.123
Wnt4wingless-related MMTV integration site 40.119
Pax6paired box gene 60.119
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.109
Cdx2caudal type homeobox 20.109
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.105
Snap25synaptosomal-associated protein 250.104
IhhIndian hedgehog0.104
Ccnd2cyclin D20.103
Socs1suppressor of cytokine signaling 10.099
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.098
SrcRous sarcoma oncogene0.098
Arid1aAT rich interactive domain 1A (SWI-like)0.098
Foxc1forkhead box C10.096
Wnt6wingless-related MMTV integration site 60.095
Rac1RAS-related C3 botulinum substrate 10.093
Hes1hairy and enhancer of split 1 (Drosophila)0.089
Vangl2vang-like 2 (van gogh, Drosophila)0.089
Fzd8frizzled homolog 8 (Drosophila)0.088
Hoxd11homeobox D110.088
Twsg1twisted gastrulation homolog 1 (Drosophila)0.087
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.086
Ror2receptor tyrosine kinase-like orphan receptor 20.086
Tgfb1transforming growth factor, beta 10.085
Meox2mesenchyme homeobox 20.085
Pax3paired box gene 30.080
BrafBraf transforming gene0.080
Dlg4discs, large homolog 4 (Drosophila)0.076
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.074
Msx2homeobox, msh-like 20.072
Smad2MAD homolog 2 (Drosophila)0.072
Dlx5distal-less homeobox 50.071
Hdac2histone deacetylase 20.071
Gli1GLI-Kruppel family member GLI10.071
Lhx9LIM homeobox protein 90.070
Dlg1discs, large homolog 1 (Drosophila)0.070
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.069
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.067
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism