The network for 'positive regulation of isotype switching to iga isotypes' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of isotype switching to iga isotypes

Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.

NameDescriptionProbabilityFunc Analog Organism
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.986
ENGendoglin0.924
FSTL1follistatin-like 10.556
TGFB3transforming growth factor, beta 30.197
TNFRSF13Btumor necrosis factor receptor superfamily, member 13B0.168
TGFBR1transforming growth factor, beta receptor 10.148
MDC1mediator of DNA-damage checkpoint 10.140
RBBP4retinoblastoma binding protein 40.102
THBS1thrombospondin 10.100
NCAPD2non-SMC condensin I complex, subunit D20.094
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.063
TNFRSF17tumor necrosis factor receptor superfamily, member 170.060
SMC1Astructural maintenance of chromosomes 1A0.049
ARandrogen receptor0.034
FUSfused in sarcoma0.030
NONOnon-POU domain containing, octamer-binding0.029
LMNB1lamin B10.026
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.025
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.024
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.024
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.021
APPamyloid beta (A4) precursor protein0.016
ILF3interleukin enhancer binding factor 3, 90kDa0.015
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.013
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.012
H2AFXH2A histone family, member X0.011
TOP1topoisomerase (DNA) I0.011
BMP2bone morphogenetic protein 20.011
TGFBR3transforming growth factor, beta receptor III0.010
HP1BP3heterochromatin protein 1, binding protein 30.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Il6stinterleukin 6 signal transducer0.013
Leprleptin receptor0.013
Trp53transformation related protein 530.011
Csf1colony stimulating factor 1 (macrophage)0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism