IMP
Process View
The network for 'positive regulation of isotype switching to iga isotypes' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of isotype switching to iga isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.986 | |
| ENG | endoglin | 0.924 | |
| FSTL1 | follistatin-like 1 | 0.556 | |
| TGFB3 | transforming growth factor, beta 3 | 0.197 | |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | 0.168 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.148 | |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.140 | |
| RBBP4 | retinoblastoma binding protein 4 | 0.102 | |
| THBS1 | thrombospondin 1 | 0.100 | |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.094 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.063 | |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.060 | |
| SMC1A | structural maintenance of chromosomes 1A | 0.049 | |
| AR | androgen receptor | 0.034 | |
| FUS | fused in sarcoma | 0.030 | |
| NONO | non-POU domain containing, octamer-binding | 0.029 | |
| LMNB1 | lamin B1 | 0.026 | |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.025 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.024 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.024 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.021 | |
| APP | amyloid beta (A4) precursor protein | 0.016 | |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.015 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.013 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.012 | |
| H2AFX | H2A histone family, member X | 0.011 | |
| TOP1 | topoisomerase (DNA) I | 0.011 | |
| BMP2 | bone morphogenetic protein 2 | 0.011 | |
| TGFBR3 | transforming growth factor, beta receptor III | 0.010 | |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.010 |
