The network for 'negative regulation of mapk cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of mapk cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.

NameDescriptionProbabilityFunc Analog Organism
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
MAPK1mitogen-activated protein kinase 10.998
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.984
EGFRepidermal growth factor receptor0.974
MAPK14mitogen-activated protein kinase 140.966
FYNFYN oncogene related to SRC, FGR, YES0.964
PTPN1protein tyrosine phosphatase, non-receptor type 10.848
MAPK8mitogen-activated protein kinase 80.801
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.796
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.795
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.788
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.761
GHRgrowth hormone receptor0.735
SH3KBP1SH3-domain kinase binding protein 10.697
MAP2K4mitogen-activated protein kinase kinase 40.678
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.674
DUSP1dual specificity phosphatase 10.672
MAP3K7mitogen-activated protein kinase kinase kinase 70.653
C1QAcomplement component 1, q subcomponent, A chain0.599
GSK3Bglycogen synthase kinase 3 beta0.526
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.515
IRAK2interleukin-1 receptor-associated kinase 20.511
ZNF43zinc finger protein 430.460
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.454
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.434
MAP2K1mitogen-activated protein kinase kinase 10.401
BCAR1breast cancer anti-estrogen resistance 10.395
TRAF6TNF receptor-associated factor 60.393
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.386
METmet proto-oncogene (hepatocyte growth factor receptor)0.348
BMPR1Abone morphogenetic protein receptor, type IA0.328
LCKlymphocyte-specific protein tyrosine kinase0.326
ZNF273zinc finger protein 2730.320
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.317
MAP3K5mitogen-activated protein kinase kinase kinase 50.311
CCNE1cyclin E10.306
CALM1calmodulin 1 (phosphorylase kinase, delta)0.298
CHUKconserved helix-loop-helix ubiquitous kinase0.290
MYD88myeloid differentiation primary response gene (88)0.261
PTPN6protein tyrosine phosphatase, non-receptor type 60.248
PDCD6IPprogrammed cell death 6 interacting protein0.244
ESR1estrogen receptor 10.236
SMAD2SMAD family member 20.231
PXNpaxillin0.225
ZNF746zinc finger protein 7460.222
CREBBPCREB binding protein0.222
ZNF675zinc finger protein 6750.220
ILKintegrin-linked kinase0.217
SC4MOLsterol-C4-methyl oxidase-like0.212
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.208
IRAK1interleukin-1 receptor-associated kinase 10.198
ZNF253zinc finger protein 2530.191
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.186
CSNK1Ecasein kinase 1, epsilon0.183
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.182
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.178
PTK2BPTK2B protein tyrosine kinase 2 beta0.177
CAV1caveolin 1, caveolae protein, 22kDa0.174
PTPN11protein tyrosine phosphatase, non-receptor type 110.166
SPRY2sprouty homolog 2 (Drosophila)0.164
JUNjun proto-oncogene0.162
GUCY2Cguanylate cyclase 2C (heat stable enterotoxin receptor)0.150
CD2APCD2-associated protein0.148
PPP6Cprotein phosphatase 6, catalytic subunit0.147
DUSP7dual specificity phosphatase 70.144
EGR1early growth response 10.143
ARRB1arrestin, beta 10.142
DUSP6dual specificity phosphatase 60.141
TICAM2toll-like receptor adaptor molecule 20.140
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.137
SCHIP1schwannomin interacting protein 10.119
NOXA1NADPH oxidase activator 10.119
DUSP23dual specificity phosphatase 230.115
DUSP3dual specificity phosphatase 30.114
YAP1Yes-associated protein 10.110
MAP2K7mitogen-activated protein kinase kinase 70.110
MED28mediator complex subunit 280.110
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.109
IRS2insulin receptor substrate 20.108
ATF2activating transcription factor 20.107
EPORerythropoietin receptor0.105
LATlinker for activation of T cells0.103
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 30.103
SHC1SHC (Src homology 2 domain containing) transforming protein 10.100
BCRbreakpoint cluster region0.098
JAK2Janus kinase 20.098
AKT1v-akt murine thymoma viral oncogene homolog 10.098
NR4A1nuclear receptor subfamily 4, group A, member 10.097
ARRB2arrestin, beta 20.095
TFF1trefoil factor 10.094
ARandrogen receptor0.094
IGF1Rinsulin-like growth factor 1 receptor0.092
CREB1cAMP responsive element binding protein 10.090
BBS10Bardet-Biedl syndrome 100.088
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.088
A2Malpha-2-macroglobulin0.086
PDCD10programmed cell death 100.086
TWF2twinfilin, actin-binding protein, homolog 2 (Drosophila)0.085
STRN3striatin, calmodulin binding protein 30.084
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.084
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mec-2Protein MEC-20.020
glr-5Protein GLR-50.011
unc-9Protein UNC-90.011
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
spry4sprouty (Drosophila) homolog 40.557
chdchordin0.287
bmp2bbone morphogenetic protein 2b0.248
spry2sprouty homolog 20.236
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.178
dusp6dual specificity phosphatase 60.157
nrg2aneuregulin 2a0.148
foxi3bforkhead box I3b0.137
ntn2netrin 20.128
gro2groucho 20.127
nf1aneurofibromin 1a0.123
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.122
etv5aets variant 5a0.117
mapk1mitogen-activated protein kinase 10.114
mapk3mitogen-activated protein kinase 30.111
adipor1badiponectin receptor 1b0.110
adipor2adiponectin receptor 20.108
ahsa1lAHA1, activator of heat shock protein ATPase homolog 1, like0.106
ppm1aaprotein phosphatase, Mg2+/Mn2+ dependent, 1Aa0.101
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.098
adipoqladiponectin, C1Q and collagen domain containing, like0.097
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.096
spns2spinster homolog 2 (Drosophila)0.091
zbtb4zinc finger and BTB domain containing 40.089
epha4aeph receptor A4a0.089
arl4abADP-ribosylation factor-like 4ab0.089
fgf3fibroblast growth factor 30.088
ip6k2inositol hexaphosphate kinase 20.087
efnb2aephrin B2a0.086
hspa4aheat shock protein 4a0.086
foxa3forkhead box A30.085
adipoql2adiponectin, C1Q and collagen domain containing, like 20.085
mapk4mitogen-activated protein kinase 40.083
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.081
tnfatumor necrosis factor a (TNF superfamily, member 2)0.080
notum3notum 30.079
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.075
per2period homolog 2 (Drosophila)0.073
gpibglucose phosphate isomerase b0.073
usp4ubiquitin specific protease 4 (proto-oncogene)0.071
ahcyl1S-adenosylhomocysteine hydrolase-like 10.070
smad1MAD homolog 1 (Drosophila)0.068
sec24cSEC24 family, member C (S. cerevisiae)0.064
nf1bneurofibromin 1b0.063
odc1ornithine decarboxylase 10.063
ism1isthmin 10.063
ralgapa1Ral GTPase activating protein, alpha subunit 1 (catalytic)0.061
gro1groucho 10.060
wwp2WW domain containing E3 ubiquitin protein ligase 20.059
phf23aPHD finger protein 23a0.058
zgc:91870zgc:918700.058
rab5cRAB5C, member RAS oncogene family0.058
wnt8bwingless-type MMTV integration site family, member 8b0.058
acvr2aactivin receptor IIa0.058
sema3fbsemaphorin 3fb0.057
gscgoosecoid0.057
mbtps1membrane-bound transcription factor protease, site 10.056
klhl11kelch-like 11 (Drosophila)0.054
lsm1LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.051
spred1sprouty-related, EVH1 domain containing 10.051
hiat1bhippocampus abundant transcript 1b0.051
smg7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)0.050
fcho2FCH domain only 20.050
ntn1bnetrin 1b0.049
bcl2l1bcl2-like 10.049
pcsk7proprotein convertase subtilisin/kexin type 70.047
phf17PHD finger protein 170.047
mxi1max interacting protein0.046
cdc42cell division cycle 420.045
lect1leukocyte cell derived chemotaxin 10.045
frem3Fras1 related extracellular matrix 30.045
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.045
tbx2bT-box 2b0.045
trim13tripartite motif-containing 130.044
kif14kinesin family member 140.043
mllt11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 110.043
spc24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.043
k31k31 gene0.043
ythdf1YTH domain family, member 10.043
pak2ap21 (CDKN1A)-activated kinase 2a0.043
slc35e1solute carrier family 35, member E10.042
zgc:153061zgc:1530610.042
zmynd19zinc finger, MYND domain containing 190.042
papolbpoly(A) polymerase beta (testis specific)0.042
zgc:56005zgc:560050.042
otx1borthodenticle homolog 1b0.042
wu:fi25h02wu:fi25h020.042
fzd8afrizzled homolog 8a0.041
npepl1aminopeptidase-like 10.040
il17rdinterleukin 17 receptor D0.040
dkk1bdickkopf 1b0.040
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.040
plk3polo-like kinase 3 (Drosophila)0.040
mpped2metallophosphoesterase domain containing 20.040
etv5bets variant 5b0.040
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.039
gclcglutamate-cysteine ligase, catalytic subunit0.039
si:dkey-177p2.6si:dkey-177p2.60.039
sfrp1asecreted frizzled-related protein 1a0.039
fzd7afrizzled homolog 7a0.039
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.364
rlrolled0.327
Ras85DRas oncogene at 85D0.261
saxsaxophone0.227
dshdishevelled0.191
Akt1CG4006 gene product from transcript CG4006-RA0.167
ash2absent, small, or homeotic discs 20.125
tkvthickveins0.112
kaykayak0.100
drkdownstream of receptor kinase0.075
Dsor1Downstream of raf10.064
SaraSmad anchor for receptor activation0.060
vgvestigial0.059
E(z)Enhancer of zeste0.057
p38bCG7393 gene product from transcript CG7393-RA0.054
prodproliferation disrupter0.053
Ras64BRas oncogene at 64B0.051
PGRP-SAPeptidoglycan recognition protein SA0.048
Sema-1aCG18405 gene product from transcript CG18405-RD0.047
CG10743CG10743 gene product from transcript CG10743-RB0.043
PGRP-LCPeptidoglycan recognition protein LC0.042
PGRP-SDCG7496 gene product from transcript CG7496-RA0.040
Src64BSrc oncogene at 64B0.039
SosSon of sevenless0.038
loqsloquacious0.038
sbbscribbler0.038
mbcmyoblast city0.037
cazcabeza0.037
foxoforkhead box, sub-group O0.036
AckCG14992 gene product from transcript CG14992-RA0.035
PGRP-LFPeptidoglycan recognition protein LF0.035
hephemipterous0.035
MerMerlin0.034
sogshort gastrulation0.034
Pp2B-14DProtein phosphatase 2B at 14D0.034
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.034
Klp64DKinesin-like protein at 64D0.033
faffat facets0.033
ShcSHC-adaptor protein0.032
CG14667CG14667 gene product from transcript CG14667-RA0.031
CalpACalpain-A0.029
osoutstretched0.029
krzkurtz0.028
PGRP-SC1bCG8577 gene product from transcript CG8577-RA0.028
Spn27ASerpin 27A0.027
Pka-C1cAMP-dependent protein kinase 10.027
mysmyospheroid0.027
LLobe0.026
Sin3ACG8815 gene product from transcript CG8815-RC0.026
grassGram-positive Specific Serine protease0.026
CG32185CG32185 gene product from transcript CG32185-RA0.025
rdgBretinal degeneration B0.025
CG3371CG3371 gene product from transcript CG3371-RA0.025
witwishful thinking0.025
sevsevenless0.025
G-oalpha47AG protein oalpha 47A0.025
rhorhomboid0.024
Rab7Rab-protein 70.024
cswcorkscrew0.024
shishibire0.023
MadMothers against dpp0.023
EndoGIEndonuclease G inhibitor0.023
Irk2Inwardly rectifying potassium channel 20.023
inaDinactivation no afterpotential D0.023
mnbminibrain0.022
ntcnutcracker0.022
stcksteamer duck0.022
JraJun-related antigen0.022
CdsACDP diglyceride synthetase0.022
shnschnurri0.022
Rab5Rab-protein 50.022
CG9316CG9316 gene product from transcript CG9316-RA0.021
dosdaughter of sevenless0.021
phlpole hole0.021
Sp7Serine protease 70.021
ApcAPC-like0.021
nbsCG6754 gene product from transcript CG6754-RC0.021
Mpk2CG5475 gene product from transcript CG5475-RB0.020
pntpointed0.020
Mkp3Mitogen-activated protein kinase phosphatase 30.019
InRInsulin-like receptor0.019
smosmoothened0.018
CG16718CG16718 gene product from transcript CG16718-RA0.018
CG9902CG9902 gene product from transcript CG9902-RA0.018
WASpCG1520 gene product from transcript CG1520-RA0.018
ninaEneither inactivation nor afterpotential E0.018
pirkpoor Imd response upon knock-in0.018
ATP7CG1886 gene product from transcript CG1886-RB0.018
Eip71CDEcdysone-induced protein 28/29kD0.018
S6kIIRPS6-protein kinase-II0.017
sdscalloped0.017
CG5439CG5439 gene product from transcript CG5439-RA0.017
Vps45Vacuolar protein sorting 450.017
Socs36ESuppressor of cytokine signaling at 36E0.017
gekgenghis khan0.017
RYBPRing and YY1 Binding Protein0.017
rutrutabaga0.017
wdbwiderborst0.017
DrsDrosomycin0.016
Myo31DFMyosin 31DF0.016
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.988
Apcadenomatosis polyposis coli0.865
Grb2growth factor receptor bound protein 20.853
Mapk1mitogen-activated protein kinase 10.825
Per2period homolog 2 (Drosophila)0.813
Mdm2transformed mouse 3T3 cell double minute 20.804
Ptenphosphatase and tensin homolog0.804
Inpp5dinositol polyphosphate-5-phosphatase D0.775
Ctnnb1catenin (cadherin associated protein), beta 10.717
Ptpn11protein tyrosine phosphatase, non-receptor type 110.705
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.664
Lyz2lysozyme 20.621
Traf6TNF receptor-associated factor 60.609
Ptprcprotein tyrosine phosphatase, receptor type, C0.592
Dok1docking protein 10.592
Fcgr2bFc receptor, IgG, low affinity IIb0.559
Axin1axin 10.526
Atf2activating transcription factor 20.520
Cd44CD44 antigen0.508
Cav1caveolin 1, caveolae protein0.467
Lcp1lymphocyte cytosolic protein 10.463
FynFyn proto-oncogene0.461
CblCasitas B-lineage lymphoma0.439
Tsc1tuberous sclerosis 10.420
Prkceprotein kinase C, epsilon0.396
Map3k7mitogen-activated protein kinase kinase kinase 70.384
Dmddystrophin, muscular dystrophy0.381
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.345
Nos1nitric oxide synthase 1, neuronal0.344
Csf1rcolony stimulating factor 1 receptor0.322
FosFBJ osteosarcoma oncogene0.309
Itgb1integrin beta 1 (fibronectin receptor beta)0.303
Mapk14mitogen-activated protein kinase 140.303
Shc1src homology 2 domain-containing transforming protein C10.297
Mapk8mitogen-activated protein kinase 80.297
Cyldcylindromatosis (turban tumor syndrome)0.292
Tnftumor necrosis factor0.291
Vaspvasodilator-stimulated phosphoprotein0.290
Rassf5Ras association (RalGDS/AF-6) domain family member 50.287
Adam17a disintegrin and metallopeptidase domain 170.262
Grb10growth factor receptor bound protein 100.258
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.255
Rb1retinoblastoma 10.252
C1qccomplement component 1, q subcomponent, C chain0.251
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.248
Cd80CD80 antigen0.247
Ly86lymphocyte antigen 860.236
Ccl4chemokine (C-C motif) ligand 40.236
Ncoa3nuclear receptor coactivator 30.229
Csf1colony stimulating factor 1 (macrophage)0.222
Il1binterleukin 1 beta0.215
Prkcbprotein kinase C, beta0.207
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.205
Tnfaip3tumor necrosis factor, alpha-induced protein 30.194
Spnb2spectrin beta 20.190
Insrinsulin receptor0.190
Mdm4transformed mouse 3T3 cell double minute 40.188
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.187
Klf7Kruppel-like factor 7 (ubiquitous)0.186
Nr3c1nuclear receptor subfamily 3, group C, member 10.185
Smad4MAD homolog 4 (Drosophila)0.185
Col1a1collagen, type I, alpha 10.181
BtkBruton agammaglobulinemia tyrosine kinase0.181
Fbxw7F-box and WD-40 domain protein 70.179
Prkccprotein kinase C, gamma0.176
SkilSKI-like0.175
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.170
Cdh5cadherin 50.165
Tgfb1transforming growth factor, beta 10.161
NsfN-ethylmaleimide sensitive fusion protein0.158
Grm1glutamate receptor, metabotropic 10.158
Usp8ubiquitin specific peptidase 80.157
Nf2neurofibromatosis 20.156
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.154
Ccnd1cyclin D10.153
Cskc-src tyrosine kinase0.153
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.153
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.152
Ptk2PTK2 protein tyrosine kinase 20.151
Ezh1enhancer of zeste homolog 1 (Drosophila)0.144
JunJun oncogene0.144
Cotl1coactosin-like 1 (Dictyostelium)0.142
Mmp9matrix metallopeptidase 90.141
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.141
Sh3kbp1SH3-domain kinase binding protein 10.136
Igf2insulin-like growth factor 20.135
Tab2TGF-beta activated kinase 1/MAP3K7 binding protein 20.130
Stat3signal transducer and activator of transcription 30.129
Sox9SRY-box containing gene 90.127
Gfra3glial cell line derived neurotrophic factor family receptor alpha 30.125
Fcgr1Fc receptor, IgG, high affinity I0.125
EvlEna-vasodilator stimulated phosphoprotein0.122
Sfrp2secreted frizzled-related protein 20.117
Ghrgrowth hormone receptor0.114
Il1r1interleukin 1 receptor, type I0.114
Il6stinterleukin 6 signal transducer0.114
Nfe2l2nuclear factor, erythroid derived 2, like 20.111
Il10interleukin 100.111
Ptpreprotein tyrosine phosphatase, receptor type, E0.111
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.111
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Junbjun B proto-oncogene0.797
FosFBJ osteosarcoma oncogene0.304
Nr4a1nuclear receptor subfamily 4, group A, member 10.164
JunJun oncogene0.161
LOC100362824caveolin 2-like0.137
Egr1early growth response 10.129
Sirpasignal-regulatory protein alpha0.115
Cav1caveolin 1, caveolae protein0.088
Klf4Kruppel-like factor 4 (gut)0.082
Ier2immediate early response 20.079
Dusp6dual specificity phosphatase 60.070
Btg2BTG family, member 20.058
Vegfavascular endothelial growth factor A0.048
Tecrtrans-2,3-enoyl-CoA reductase0.046
Cav2caveolin 20.044
Rab1bRAB1B, member RAS oncogene family0.042
Fmnl1formin-like 10.037
Klf6Kruppel-like factor 60.034
SnrkSNF related kinase0.031
Prkcdprotein kinase C, delta0.028
Ralgdsral guanine nucleotide dissociation stimulator0.027
Tsc22d3TSC22 domain family, member 30.026
Klf2Kruppel-like factor 2 (lung)0.026
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.026
Gprc5aG protein-coupled receptor, family C, group 5, member A0.024
Jdp2Jun dimerization protein 20.024
Rps6ka1ribosomal protein S6 kinase polypeptide 10.024
Pink1PTEN induced putative kinase 10.023
Serinc1serine incorporator 10.021
Rassf5Ras association (RalGDS/AF-6) domain family member 50.021
Egr2early growth response 20.021
Klf9Kruppel-like factor 90.021
Cd37CD37 molecule0.021
Cugbp2CUG triplet repeat, RNA binding protein 20.020
Gna12guanine nucleotide binding protein (G protein) alpha 120.019
Matkmegakaryocyte-associated tyrosine kinase0.019
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.019
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.018
Slc48a1solute carrier family 48 (heme transporter), member 10.018
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.018
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.017
Homer1homer homolog 1 (Drosophila)0.017
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.017
Slc30a4solute carrier family 30 (zinc transporter), member 40.017
Ptk2bPTK2B protein tyrosine kinase 2 beta0.017
Sbk1SH3-binding domain kinase 10.017
Zfp36zinc finger protein 360.017
Usf2upstream transcription factor 2, c-fos interacting0.017
Scarb1scavenger receptor class B, member 10.016
Cltcclathrin, heavy chain (Hc)0.016
Ptp4a2protein tyrosine phosphatase 4a20.016
Gstm1glutathione S-transferase mu 10.016
Atxn1ataxin 10.016
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.015
Rhoaras homolog gene family, member A0.015
Ctsfcathepsin F0.015
Hist1h1ahistone cluster 1, H1a0.015
Crip2cysteine-rich protein 20.015
Crygccrystallin, gamma C0.015
Stk10serine/threonine kinase 100.015
Arnt2aryl hydrocarbon receptor nuclear translocator 20.015
Inpp5dinositol polyphosphate-5-phosphatase D0.014
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.014
Fgfr1Fibroblast growth factor receptor 10.014
Cdc42se1CDC42 small effector 10.014
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.014
Wipf1WAS/WASL interacting protein family, member 10.014
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.014
Adrbk1adrenergic, beta, receptor kinase 10.013
Vegfbvascular endothelial growth factor B0.013
Ddndendrin0.013
Pdk2pyruvate dehydrogenase kinase, isozyme 20.013
Spata2Lspermatogenesis associated 2-like0.013
Gja1gap junction protein, alpha 10.013
AdprhADP-ribosylarginine hydrolase0.013
Gpr116G protein-coupled receptor 1160.013
Gpx4glutathione peroxidase 40.013
Pcdhga11protocadherin gamma subfamily A, 110.013
Akap1A kinase (PRKA) anchor protein 10.013
Ptprcprotein tyrosine phosphatase, receptor type, C0.013
Kcnn1potassium intermediate/small conductance calcium-activated channel, subfamily N, member 10.012
Cxcl12chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)0.012
Sox4SRY (sex determining region Y)-box 40.012
Synposynaptopodin0.012
Cxcr7chemokine (C-X-C motif) receptor 70.012
Fbxo2F-box protein 20.012
Gsrglutathione reductase0.012
DbpD site of albumin promoter (albumin D-box) binding protein0.012
Tgfb1transforming growth factor, beta 10.012
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.012
Abcb4ATP-binding cassette, subfamily B (MDR/TAP), member 40.012
Stx6syntaxin 60.012
Dusp1dual specificity phosphatase 10.012
Ptproprotein tyrosine phosphatase, receptor type, O0.012
Errfi1ERBB receptor feedback inhibitor 10.012
Gdaguanine deaminase0.011
Epn2epsin 20.011
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.011
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.011
Cntfrciliary neurotrophic factor receptor0.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
KSS1Kss1p0.967
SLT2Slt2p0.647
FUS3Fus3p0.643
STE7Ste7p0.464
MSG5Msg5p0.350
STE11Ste11p0.339
NBP2Nbp2p0.299
BOI1Boi1p0.258
KDX1Kdx1p0.157
RLM1Rlm1p0.128
STE5Ste5p0.120
PBS2Pbs2p0.111
PPH21Pph21p0.077
BCK1Bck1p0.073
IRA1Ira1p0.063
CDC55Cdc55p0.057
VMA13Vma13p0.052
SSK22Ssk22p0.049
TEC1Tec1p0.046
LHS1Lhs1p0.044
SSK2Ssk2p0.044
SLA2Sla2p0.042
BOI2Boi2p0.040
SSK1Ssk1p0.039
MYO5Myo5p0.039
BCK2Bck2p0.039
YPL088Whypothetical protein0.036
STE12Ste12p0.031
SHO1Sho1p0.028
HKR1Hkr1p0.027
GAL7Gal7p0.027
RPN2Rpn2p0.025
STE20Ste20p0.025
SKM1Skm1p0.023
CNE1Cne1p0.023
YGR205Whypothetical protein0.023
STE18Ste18p0.022
CAK1Cak1p0.021
ARE2Are2p0.020
PPH22Pph22p0.020
VPS5Vps5p0.019
YOR111Whypothetical protein0.018
INP53Inp53p0.018
PTC2Ptc2p0.017
DFG5Dfg5p0.017
YER071Chypothetical protein0.017
MKK2Mkk2p0.017
PRS2Prs2p0.016
BUD7Bud7p0.016
ULA1Ula1p0.016
TWF1Twf1p0.016
ESF1Esf1p0.016
SRD1Srd1p0.016
CRG1Crg1p0.015
ARP10Arp10p0.015
TIP41Tip41p0.015
RGD1Rgd1p0.015
LEU2Leu2p0.015
SFA1Sfa1p0.015
CAM1Cam1p0.014
YNR014Whypothetical protein0.014
YLR264C-Ahypothetical protein0.014
RHO1Rho1p0.014
YCF1Ycf1p0.014
URA3Ura3p0.014
KNH1Knh1p0.014
CRZ1Crz1p0.014
TFA2Tfa2p0.014
YIL151Chypothetical protein0.013
YHB1Yhb1p0.013
YOL038C-Ahypothetical protein0.013
CUP1-1Cup1-1p0.013
MER1Mer1p0.013
YLR162Whypothetical protein0.012
SFB3Sfb3p0.012
SOK1Sok1p0.012
STE4Ste4p0.012
RPN14Rpn14p0.012
ROM2Rom2p0.012
OSH3Osh3p0.012
YLR042Chypothetical protein0.012
TIP1Tip1p0.012
ARK1Ark1p0.012
YCH1Ych1p0.012
TRS65Trs65p0.012
PNS1Pns1p0.012
YMR295Chypothetical protein0.012
HXT3Hxt3p0.012
KIC1Kic1p0.011
PRM5Prm5p0.011
PPQ1Ppq1p0.011
OPY1Opy1p0.011
YIR035Chypothetical protein0.011
YLR194Chypothetical protein0.011
MGR1Mgr1p0.011
AIM25Aim25p0.010
GAT1Gat1p0.010
PAA1Paa1p0.010
YBR013Chypothetical protein0.010
CHA1Cha1p0.010