The network for 'positive regulation of peptidyl serine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of peptidyl serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

NameDescriptionProbabilityFunc Analog Organism
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.997
EGFRepidermal growth factor receptor0.993
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.980
SH3KBP1SH3-domain kinase binding protein 10.966
CAV1caveolin 1, caveolae protein, 22kDa0.948
GRB2growth factor receptor-bound protein 20.902
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.898
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.855
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.847
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.834
BIRC3baculoviral IAP repeat containing 30.820
SH2D4ASH2 domain containing 4A0.693
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.668
SHC1SHC (Src homology 2 domain containing) transforming protein 10.616
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.595
PTPN1protein tyrosine phosphatase, non-receptor type 10.574
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.542
VEGFAvascular endothelial growth factor A0.517
AXLAXL receptor tyrosine kinase0.511
WASLWiskott-Aldrich syndrome-like0.462
WIPF1WAS/WASL interacting protein family, member 10.431
PRDX1peroxiredoxin 10.415
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.390
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.378
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.352
IQGAP1IQ motif containing GTPase activating protein 10.323
BRAFv-raf murine sarcoma viral oncogene homolog B10.317
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.297
NTRK1neurotrophic tyrosine kinase, receptor, type 10.290
MAGEA11melanoma antigen family A, 110.287
IGF1Rinsulin-like growth factor 1 receptor0.261
LRRK2leucine-rich repeat kinase 20.260
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.252
NRP1neuropilin 10.238
SYKspleen tyrosine kinase0.219
LATlinker for activation of T cells0.212
IRS1insulin receptor substrate 10.212
BCAR1breast cancer anti-estrogen resistance 10.194
PRKCZprotein kinase C, zeta0.192
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.191
ACTBactin, beta0.188
TRAF1TNF receptor-associated factor 10.175
SQSTM1sequestosome 10.172
INSRinsulin receptor0.171
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.170
CASP8caspase 8, apoptosis-related cysteine peptidase0.161
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.157
BCL2L1BCL2-like 10.152
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.149
FYNFYN oncogene related to SRC, FGR, YES0.147
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.139
PCDHA4protocadherin alpha 40.139
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.136
NTRK3neurotrophic tyrosine kinase, receptor, type 30.133
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.131
HDAC7histone deacetylase 70.129
TRAF3TNF receptor-associated factor 30.128
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.124
TEKTEK tyrosine kinase, endothelial0.120
GHRgrowth hormone receptor0.114
NTRK2neurotrophic tyrosine kinase, receptor, type 20.112
PDGFCplatelet derived growth factor C0.110
PLAURplasminogen activator, urokinase receptor0.109
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.106
MAPTmicrotubule-associated protein tau0.097
LRP6low density lipoprotein receptor-related protein 60.096
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.095
ANGPT1angiopoietin 10.094
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.083
IL6Rinterleukin 6 receptor0.083
METmet proto-oncogene (hepatocyte growth factor receptor)0.082
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.081
SORBS2sorbin and SH3 domain containing 20.078
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.077
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.076
LIMK1LIM domain kinase 10.074
PTENphosphatase and tensin homolog0.073
ARRB1arrestin, beta 10.072
FASFas (TNF receptor superfamily, member 6)0.069
TESK1testis-specific kinase 10.068
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.066
PTPRBprotein tyrosine phosphatase, receptor type, B0.064
CRMP1collapsin response mediator protein 10.063
DLG1discs, large homolog 1 (Drosophila)0.063
MPDZmultiple PDZ domain protein0.063
ITSN1intersectin 1 (SH3 domain protein)0.062
PLEKHA1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 10.060
CDK11Bcyclin-dependent kinase 11B0.060
YAP1Yes-associated protein 10.060
TNFAIP3tumor necrosis factor, alpha-induced protein 30.059
MAP3K5mitogen-activated protein kinase kinase kinase 50.058
PLCG1phospholipase C, gamma 10.058
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.058
ARRB2arrestin, beta 20.057
FLNAfilamin A, alpha0.056
CCL14chemokine (C-C motif) ligand 140.055
NTF4neurotrophin 40.055
SSTR2somatostatin receptor 20.054
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
grl-7Protein GRL-70.014
C49F8.3Protein C49F8.30.011
gst-36Protein GST-360.011
T27A1.5Protein T27A1.50.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.926
Ptgs2prostaglandin-endoperoxide synthase 20.905
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.855
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.835
Retret proto-oncogene0.678
Apcadenomatosis polyposis coli0.636
Bcl2B-cell leukemia/lymphoma 20.628
BaxBCL2-associated X protein0.619
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.578
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.533
Ntf3neurotrophin 30.510
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.447
Nos3nitric oxide synthase 3, endothelial cell0.415
Dkk1dickkopf homolog 1 (Xenopus laevis)0.373
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.361
Gsk3bglycogen synthase kinase 3 beta0.359
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.359
Ptenphosphatase and tensin homolog0.342
Ccl2chemokine (C-C motif) ligand 20.331
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.328
Bdnfbrain derived neurotrophic factor0.305
Pax2paired box gene 20.292
Gab1growth factor receptor bound protein 2-associated protein 10.249
Nr2f1nuclear receptor subfamily 2, group F, member 10.239
Rac1RAS-related C3 botulinum substrate 10.232
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.218
Il1r1interleukin 1 receptor, type I0.213
Akt1thymoma viral proto-oncogene 10.211
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.210
Ren1renin 1 structural0.200
Vegfavascular endothelial growth factor A0.193
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.188
Nrg1neuregulin 10.188
Smad3MAD homolog 3 (Drosophila)0.185
Il6stinterleukin 6 signal transducer0.184
Itgb1integrin beta 1 (fibronectin receptor beta)0.179
BrafBraf transforming gene0.167
Tlr4toll-like receptor 40.167
Gdnfglial cell line derived neurotrophic factor0.166
Rargretinoic acid receptor, gamma0.164
Lhx1LIM homeobox protein 10.162
Kdrkinase insert domain protein receptor0.159
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.157
Ptprbprotein tyrosine phosphatase, receptor type, B0.149
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.145
Arpc4actin related protein 2/3 complex, subunit 40.140
Nos2nitric oxide synthase 2, inducible0.138
Wnt4wingless-related MMTV integration site 40.138
Leprleptin receptor0.127
Gpc3glypican 30.118
Pou3f3POU domain, class 3, transcription factor 30.112
Actbactin, beta0.106
Vdrvitamin D receptor0.106
Esr2estrogen receptor 2 (beta)0.101
Trp53transformation related protein 530.096
Ptpn11protein tyrosine phosphatase, non-receptor type 110.095
Emid2EMI domain containing 20.091
Hoxa1homeobox A10.090
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.090
Wt1Wilms tumor 1 homolog0.085
Stat3signal transducer and activator of transcription 30.085
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.085
Irs1insulin receptor substrate 10.082
Ntf5neurotrophin 50.081
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.076
Fzd1frizzled homolog 1 (Drosophila)0.075
Agtr1aangiotensin II receptor, type 1a0.075
Phox2apaired-like homeobox 2a0.072
Ppargperoxisome proliferator activated receptor gamma0.068
Notch2Notch gene homolog 2 (Drosophila)0.068
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.065
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.064
Hspb8heat shock protein 80.063
Capn1calpain 10.063
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.062
Bmpr1abone morphogenetic protein receptor, type 1A0.061
Cdh5cadherin 50.061
Itsn1intersectin 1 (SH3 domain protein 1A)0.061
Fgf18fibroblast growth factor 180.059
Ror1receptor tyrosine kinase-like orphan receptor 10.059
Kitkit oncogene0.057
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.057
Efna4ephrin A40.056
Grb2growth factor receptor bound protein 20.055
C1ql1complement component 1, q subcomponent-like 10.055
RictorRPTOR independent companion of MTOR, complex 20.055
Apoeapolipoprotein E0.054
Batfbasic leucine zipper transcription factor, ATF-like0.053
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.053
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.051
Cskc-src tyrosine kinase0.050
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.049
Rararetinoic acid receptor, alpha0.049
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.048
Tgfb1transforming growth factor, beta 10.048
Fzd4frizzled homolog 4 (Drosophila)0.048
Mapkapk2MAP kinase-activated protein kinase 20.048
Ednrbendothelin receptor type B0.047
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism