The network for 'regulation of peptidyl serine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of peptidyl serine phosphorylation

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.

NameDescriptionProbabilityFunc Analog Organism
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.997
SMAD3SMAD family member 30.988
TRAF1TNF receptor-associated factor 10.837
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.754
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.696
SH3KBP1SH3-domain kinase binding protein 10.695
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.684
SMAD2SMAD family member 20.676
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.657
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.602
VEGFAvascular endothelial growth factor A0.572
CAV1caveolin 1, caveolae protein, 22kDa0.565
SH2D4ASH2 domain containing 4A0.522
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.502
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.488
BIRC3baculoviral IAP repeat containing 30.418
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.398
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.363
SMURF2SMAD specific E3 ubiquitin protein ligase 20.362
SMAD1SMAD family member 10.348
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.338
NCF1neutrophil cytosolic factor 10.333
BRAFv-raf murine sarcoma viral oncogene homolog B10.326
EGFRepidermal growth factor receptor0.314
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.302
NRP1neuropilin 10.287
BCL2L1BCL2-like 10.283
TEKTEK tyrosine kinase, endothelial0.270
CDC37cell division cycle 37 homolog (S. cerevisiae)0.260
AXLAXL receptor tyrosine kinase0.231
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.222
DTNAdystrobrevin, alpha0.220
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.218
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.216
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.210
PRDX1peroxiredoxin 10.209
LRP6low density lipoprotein receptor-related protein 60.209
NR4A3nuclear receptor subfamily 4, group A, member 30.206
NOXA1NADPH oxidase activator 10.206
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.204
MAPTmicrotubule-associated protein tau0.204
FHL1four and a half LIM domains 10.203
FYNFYN oncogene related to SRC, FGR, YES0.194
PRKCZprotein kinase C, zeta0.194
BIRC2baculoviral IAP repeat containing 20.194
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.187
ANGPT2angiopoietin 20.186
NTRK1neurotrophic tyrosine kinase, receptor, type 10.179
IL8interleukin 80.177
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.165
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.165
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.160
SMAD5SMAD family member 50.154
SMAD7SMAD family member 70.152
ARRB2arrestin, beta 20.151
BAK1BCL2-antagonist/killer 10.150
MAGEA11melanoma antigen family A, 110.147
YAP1Yes-associated protein 10.146
ANGPT1angiopoietin 10.144
BADBCL2-associated agonist of cell death0.132
SHC1SHC (Src homology 2 domain containing) transforming protein 10.131
TGFBR1transforming growth factor, beta receptor 10.130
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.127
PTPRNprotein tyrosine phosphatase, receptor type, N0.125
SH3RF1SH3 domain containing ring finger 10.124
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.117
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.111
WIPF1WAS/WASL interacting protein family, member 10.105
NGFnerve growth factor (beta polypeptide)0.103
LATlinker for activation of T cells0.102
IL6Rinterleukin 6 receptor0.102
ENGendoglin0.098
DLG1discs, large homolog 1 (Drosophila)0.094
CDK11Bcyclin-dependent kinase 11B0.093
SQSTM1sequestosome 10.088
PRKCAprotein kinase C, alpha0.084
PDGFCplatelet derived growth factor C0.081
MSNmoesin0.079
GHRgrowth hormone receptor0.079
TESK1testis-specific kinase 10.078
BDNFbrain-derived neurotrophic factor0.076
VAC14Vac14 homolog (S. cerevisiae)0.076
NCF2neutrophil cytosolic factor 20.075
YY1YY1 transcription factor0.073
ARRB1arrestin, beta 10.073
SMAD4SMAD family member 40.069
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.069
PDE4DIPphosphodiesterase 4D interacting protein0.067
SKIv-ski sarcoma viral oncogene homolog (avian)0.066
NTF3neurotrophin 30.065
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.065
KSR1kinase suppressor of ras 10.061
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.061
METmet proto-oncogene (hepatocyte growth factor receptor)0.061
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.060
CXXC5CXXC finger protein 50.059
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.059
FBXO7F-box protein 70.059
MAP2K1mitogen-activated protein kinase kinase 10.058
IQGAP1IQ motif containing GTPase activating protein 10.058
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smad3MAD homolog 3 (Drosophila)0.996
Nos3nitric oxide synthase 3, endothelial cell0.996
Apcadenomatosis polyposis coli0.989
Ptenphosphatase and tensin homolog0.980
Ptgs2prostaglandin-endoperoxide synthase 20.977
Ctnnb1catenin (cadherin associated protein), beta 10.974
Smad4MAD homolog 4 (Drosophila)0.963
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.949
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.924
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.906
Leprleptin receptor0.879
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.875
Nos2nitric oxide synthase 2, inducible0.875
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.847
Ren1renin 1 structural0.821
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.821
Axin1axin 10.818
BaxBCL2-associated X protein0.788
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.742
Arrb2arrestin, beta 20.722
Nr3c1nuclear receptor subfamily 3, group C, member 10.716
Sfrp1secreted frizzled-related protein 10.702
Pax2paired box gene 20.678
Nos1nitric oxide synthase 1, neuronal0.632
Bcl2B-cell leukemia/lymphoma 20.631
Gsk3bglycogen synthase kinase 3 beta0.628
Dkk1dickkopf homolog 1 (Xenopus laevis)0.538
Stat3signal transducer and activator of transcription 30.530
Gab1growth factor receptor bound protein 2-associated protein 10.523
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.464
Wt1Wilms tumor 1 homolog0.426
Tgfb1transforming growth factor, beta 10.402
Kdrkinase insert domain protein receptor0.394
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.391
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.378
Retret proto-oncogene0.358
Rac1RAS-related C3 botulinum substrate 10.353
Arrb1arrestin, beta 10.350
Wnt5awingless-related MMTV integration site 5A0.347
Smad1MAD homolog 1 (Drosophila)0.332
Bdnfbrain derived neurotrophic factor0.330
Agtr1aangiotensin II receptor, type 1a0.326
Esr1estrogen receptor 1 (alpha)0.325
Il6stinterleukin 6 signal transducer0.323
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.301
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.300
BrafBraf transforming gene0.289
Ank1ankyrin 1, erythroid0.265
Fzd1frizzled homolog 1 (Drosophila)0.254
Fgfr3fibroblast growth factor receptor 30.243
Vegfavascular endothelial growth factor A0.243
Pgrprogesterone receptor0.239
Erbb2ipErbb2 interacting protein0.237
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.232
Il10interleukin 100.228
Klhl24kelch-like 24 (Drosophila)0.227
Stk11serine/threonine kinase 110.225
Actbactin, beta0.218
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.216
Pax8paired box gene 80.211
Flt4FMS-like tyrosine kinase 40.203
Vdrvitamin D receptor0.190
Rnf111ring finger 1110.189
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.187
Kitlkit ligand0.186
Drd2dopamine receptor D20.185
Arpc4actin related protein 2/3 complex, subunit 40.183
Wnt6wingless-related MMTV integration site 60.181
Sfrp2secreted frizzled-related protein 20.176
RictorRPTOR independent companion of MTOR, complex 20.173
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.172
Smurf2SMAD specific E3 ubiquitin protein ligase 20.172
FasFas (TNF receptor superfamily member 6)0.170
Pecam1platelet/endothelial cell adhesion molecule 10.165
Ptprbprotein tyrosine phosphatase, receptor type, B0.165
Lhx1LIM homeobox protein 10.161
Cav1caveolin 1, caveolae protein0.161
Foxa2forkhead box A20.159
Bmpr1abone morphogenetic protein receptor, type 1A0.159
Lrrk2leucine-rich repeat kinase 20.155
Esr2estrogen receptor 2 (beta)0.153
Nfe2l2nuclear factor, erythroid derived 2, like 20.152
Prkg1protein kinase, cGMP-dependent, type I0.150
Nr2f1nuclear receptor subfamily 2, group F, member 10.150
Cfl1cofilin 1, non-muscle0.149
Cdh5cadherin 50.149
En1engrailed 10.146
Grb2growth factor receptor bound protein 20.145
Bdkrb2bradykinin receptor, beta 20.141
Il1r1interleukin 1 receptor, type I0.141
Irs1insulin receptor substrate 10.138
Kitkit oncogene0.131
Spry4sprouty homolog 4 (Drosophila)0.130
Smurf1SMAD specific E3 ubiquitin protein ligase 10.130
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.129
Dvl2dishevelled 2, dsh homolog (Drosophila)0.124
Inpp5dinositol polyphosphate-5-phosphatase D0.124
Ghrgrowth hormone receptor0.123
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.121
Ror1receptor tyrosine kinase-like orphan receptor 10.121
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism