The network for 'regulation of centriole replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of centriole replication

Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.

NameDescriptionProbabilityFunc Analog Organism
FARSAphenylalanyl-tRNA synthetase, alpha subunit0.165
RPL18ribosomal protein L180.074
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.070
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.057
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.056
STOML2stomatin (EPB72)-like 20.053
SRSF1serine/arginine-rich splicing factor 10.051
RPL8ribosomal protein L80.030
ILF3interleukin enhancer binding factor 3, 90kDa0.029
RPL23ribosomal protein L230.028
RUVBL2RuvB-like 2 (E. coli)0.026
MRPS2mitochondrial ribosomal protein S20.025
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.023
EBNA1BP2EBNA1 binding protein 20.023
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.020
SYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting protein0.019
SRSF3serine/arginine-rich splicing factor 30.018
SNRPBsmall nuclear ribonucleoprotein polypeptides B and B10.016
ATP5G1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)0.015
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.015
CCT2chaperonin containing TCP1, subunit 2 (beta)0.015
HNRNPRheterogeneous nuclear ribonucleoprotein R0.014
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.014
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.014
CYC1cytochrome c-10.013
TOMM40translocase of outer mitochondrial membrane 40 homolog (yeast)0.013
NDUFB2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa0.012
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.012
TRA2Btransformer 2 beta homolog (Drosophila)0.012
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.012
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.012
MCM7minichromosome maintenance complex component 70.012
CBX3chromobox homolog 30.011
MCM5minichromosome maintenance complex component 50.011
MRPL4mitochondrial ribosomal protein L40.011
WDR77WD repeat domain 770.011
DDX18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.011
PRMT5protein arginine methyltransferase 50.011
LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.011
PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)0.010
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.010
DHX15DEAH (Asp-Glu-Ala-His) box polypeptide 150.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
EgfrEpidermal growth factor receptor0.130
phlpole hole0.091
HopHsp70/Hsp90 organizing protein homolog0.028
Rpd3CG7471 gene product from transcript CG7471-RA0.027
Aos1CG12276 gene product from transcript CG12276-RA0.024
TorTarget of rapamycin0.021
Rho1CG8416 gene product from transcript CG8416-RB0.020
BEAF-32Boundary element-associated factor of 32kD0.019
Fas2Fasciclin 20.019
EcREcdysone receptor0.017
CG18292CG18292 gene product from transcript CG18292-RA0.014
Rac1CG2248 gene product from transcript CG2248-RA0.013
CG9797CG9797 gene product from transcript CG9797-RA0.011
ctpcut up0.011
slmbsupernumerary limbs0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smc2structural maintenance of chromosomes 20.417
Ect2ect2 oncogene0.383
Anlnanillin, actin binding protein0.270
Trim59tripartite motif-containing 590.264
Smc4structural maintenance of chromosomes 40.231
Per1period homolog 1 (Drosophila)0.136
Per2period homolog 2 (Drosophila)0.133
Cstf2cleavage stimulation factor, 3' pre-RNA subunit 20.112
C330027C09RikRIKEN cDNA C330027C09 gene0.103
Cdc7cell division cycle 7 (S. cerevisiae)0.102
Kif2akinesin family member 2A0.088
Hnrpllheterogeneous nuclear ribonucleoprotein L-like0.088
Spag5sperm associated antigen 50.082
Ncapg2non-SMC condensin II complex, subunit G20.080
Shcbp1Shc SH2-domain binding protein 10.064
Prc1protein regulator of cytokinesis 10.060
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.058
Prim2DNA primase, p58 subunit0.057
Haus6HAUS augmin-like complex, subunit 60.051
Ccnb1cyclin B10.050
Usp1ubiquitin specific peptidase 10.045
Ezh2enhancer of zeste homolog 2 (Drosophila)0.045
2610039C10RikRIKEN cDNA 2610039C10 gene0.045
Hellshelicase, lymphoid specific0.040
Pola1polymerase (DNA directed), alpha 10.037
Racgap1Rac GTPase-activating protein 10.036
RecqlRecQ protein-like0.034
Dckdeoxycytidine kinase0.033
Lancl2LanC (bacterial lantibiotic synthetase component C)-like 20.032
Lin9lin-9 homolog (C. elegans)0.032
Dsn1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)0.031
Rbbp8retinoblastoma binding protein 80.030
Brca1breast cancer 10.030
Wdhd1WD repeat and HMG-box DNA binding protein 10.030
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.029
BlmBloom syndrome, RecQ helicase-like0.029
Rad18RAD18 homolog (S. cerevisiae)0.029
Topbp1topoisomerase (DNA) II binding protein 10.029
Chek1checkpoint kinase 1 homolog (S. pombe)0.026
Kif11kinesin family member 110.025
MtbpMdm2, transformed 3T3 cell double minute p53 binding protein0.024
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.024
Trip13thyroid hormone receptor interactor 130.022
Ncbp2nuclear cap binding protein subunit 20.021
Sass6spindle assembly 6 homolog (C. elegans)0.020
Adssadenylosuccinate synthetase, non muscle0.019
Wee1WEE 1 homolog 1 (S. pombe)0.019
DekDEK oncogene (DNA binding)0.018
Ckap5cytoskeleton associated protein 50.018
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.017
Slbpstem-loop binding protein0.017
Ccna2cyclin A20.017
ZwilchZwilch, kinetochore associated, homolog (Drosophila)0.016
Brca2breast cancer 20.016
Dnajc10DnaJ (Hsp40) homolog, subfamily C, member 100.016
Ncapgnon-SMC condensin I complex, subunit G0.016
Cry2cryptochrome 2 (photolyase-like)0.015
Mns1meiosis-specific nuclear structural protein 10.015
Ctnnb1catenin (cadherin associated protein), beta 10.015
Rad51ap1RAD51 associated protein 10.014
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.014
Rad51RAD51 homolog (S. cerevisiae)0.014
Csnk1ecasein kinase 1, epsilon0.014
Tipintimeless interacting protein0.014
Pdk3pyruvate dehydrogenase kinase, isoenzyme 30.013
Ncaphnon-SMC condensin I complex, subunit H0.013
Prim1DNA primase, p49 subunit0.013
Psip1PC4 and SFRS1 interacting protein 10.013
Usp2ubiquitin specific peptidase 20.013
Myef2myelin basic protein expression factor 2, repressor0.013
Donsondownstream neighbor of SON0.012
Mre11ameiotic recombination 11 homolog A (S. cerevisiae)0.012
2700029M09RikRIKEN cDNA 2700029M09 gene0.012
Phtf1putative homeodomain transcription factor 10.012
TtkTtk protein kinase0.011
4930534B04RikRIKEN cDNA 4930534B04 gene0.011
Ube2tubiquitin-conjugating enzyme E2T (putative)0.011
Apcadenomatosis polyposis coli0.011
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.011
Rrm1ribonucleotide reductase M10.011
Nrasneuroblastoma ras oncogene0.011
Tpx2TPX2, microtubule-associated protein homolog (Xenopus laevis)0.010
Arl6ADP-ribosylation factor-like 60.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism