The network for 'positive regulation of cell cycle process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell cycle process

Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

NameDescriptionProbabilityFunc Analog Organism
CDK2cyclin-dependent kinase 21.000
EGFRepidermal growth factor receptor0.992
TP53tumor protein p530.976
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.968
RB1retinoblastoma 10.966
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.965
CDC20cell division cycle 20 homolog (S. cerevisiae)0.965
CCND1cyclin D10.897
CCNA2cyclin A20.891
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.887
SKP2S-phase kinase-associated protein 2 (p45)0.832
E2F1E2F transcription factor 10.806
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.790
AURKBaurora kinase B0.783
MDM2Mdm2 p53 binding protein homolog (mouse)0.771
CDC27cell division cycle 27 homolog (S. cerevisiae)0.770
CDK6cyclin-dependent kinase 60.763
RBL1retinoblastoma-like 1 (p107)0.757
CASP3caspase 3, apoptosis-related cysteine peptidase0.743
NCF1neutrophil cytosolic factor 10.728
EP300E1A binding protein p3000.725
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.708
CHEK2CHK2 checkpoint homolog (S. pombe)0.700
BRCA1breast cancer 1, early onset0.697
GRB10growth factor receptor-bound protein 100.695
CBX5chromobox homolog 50.680
RXRAretinoid X receptor, alpha0.655
GSK3Bglycogen synthase kinase 3 beta0.627
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.625
CDK1cyclin-dependent kinase 10.624
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.614
E2F7E2F transcription factor 70.596
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.569
CCNB1cyclin B10.555
MAP3K5mitogen-activated protein kinase kinase kinase 50.548
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.538
JUPjunction plakoglobin0.534
TAL1T-cell acute lymphocytic leukemia 10.495
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.494
KRT14keratin 140.490
CASP2caspase 2, apoptosis-related cysteine peptidase0.489
CCNE1cyclin E10.488
XIAPX-linked inhibitor of apoptosis0.479
CCNB2cyclin B20.472
MCM7minichromosome maintenance complex component 70.469
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.461
RACGAP1Rac GTPase activating protein 10.447
NOTCH1notch 10.443
PLK1polo-like kinase 10.434
ARHGAP10Rho GTPase activating protein 100.430
E2F8E2F transcription factor 80.428
CDC6cell division cycle 6 homolog (S. cerevisiae)0.426
CDT1chromatin licensing and DNA replication factor 10.422
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.419
CKS1BCDC28 protein kinase regulatory subunit 1B0.417
CDCA8cell division cycle associated 80.382
BIRC5baculoviral IAP repeat containing 50.379
ORC2origin recognition complex, subunit 20.377
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.365
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.361
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.333
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.331
CDC45cell division cycle 45 homolog (S. cerevisiae)0.326
CCND3cyclin D30.322
ACTN2actinin, alpha 20.321
SKP1S-phase kinase-associated protein 10.321
FASLGFas ligand (TNF superfamily, member 6)0.317
APAF1apoptotic peptidase activating factor 10.312
CDC26cell division cycle 26 homolog (S. cerevisiae)0.308
PTPN1protein tyrosine phosphatase, non-receptor type 10.308
CAV1caveolin 1, caveolae protein, 22kDa0.302
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.299
RAD51CRAD51 homolog C (S. cerevisiae)0.295
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.292
UBE2Cubiquitin-conjugating enzyme E2C0.288
PAX3paired box 30.288
C19orf39chromosome 19 open reading frame 390.285
CDKN3cyclin-dependent kinase inhibitor 30.283
CD80CD80 molecule0.276
HDAC1histone deacetylase 10.275
CHEK1CHK1 checkpoint homolog (S. pombe)0.273
CCR2chemokine (C-C motif) receptor 20.272
CD86CD86 molecule0.262
RBX1ring-box 1, E3 ubiquitin protein ligase0.254
STAG2stromal antigen 20.245
CCL5chemokine (C-C motif) ligand 50.244
STON2stonin 20.243
CDK9cyclin-dependent kinase 90.239
NRP1neuropilin 10.235
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.234
UHRF2ubiquitin-like with PHD and ring finger domains 20.234
LIN9lin-9 homolog (C. elegans)0.233
FOXM1forkhead box M10.233
SMAD2SMAD family member 20.226
VHLvon Hippel-Lindau tumor suppressor0.223
JAK2Janus kinase 20.219
LRDDleucine-rich repeats and death domain containing0.219
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.216
TPBGtrophoblast glycoprotein0.215
CASP8caspase 8, apoptosis-related cysteine peptidase0.212
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
trr-1Protein TRR-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dapdacapo0.786
Akt1CG4006 gene product from transcript CG4006-RA0.683
CycBCyclin B0.560
bskbasket0.424
malphaE(spl) region transcript malpha0.348
HLHmbetaE(spl) region transcript mbeta0.318
aspabnormal spindle0.228
armarmadillo0.211
dupdouble parked0.186
HLHmdeltaE(spl) region transcript mdelta0.183
HLHm5E(spl) region transcript m50.177
CycECyclin E0.175
HLHmgammaE(spl) region transcript mgamma0.163
Kmn1kinetochore Mis12-Ndc80 network component 10.157
pblpebble0.145
aopanterior open0.141
MadMothers against dpp0.122
twstwins0.118
spispitz0.118
bazbazooka0.107
stgstring0.105
egeagle0.100
dmdiminutive0.099
SoxNSoxNeuro0.093
NetBNetrin-B0.090
myoglianinCG1838 gene product from transcript CG1838-RD0.089
ari-2ariadne 20.087
numbCG3779 gene product from transcript CG3779-RB0.086
dshdishevelled0.086
BicDBicaudal D0.086
HLHm7E(spl) region transcript m70.083
bratbrain tumor0.081
ttktramtrack0.081
CycACyclin A0.079
spn-Bspindle B0.077
orboo18 RNA-binding protein0.076
ChroChromator0.075
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.074
Psf2CG18013 gene product from transcript CG18013-RA0.073
nejnejire0.073
DetDeterin0.071
ctaconcertina0.069
Su(H)Suppressor of Hairless0.066
gishgilgamesh0.065
trctricornered0.063
glugluon0.063
mbcmyoblast city0.063
shnschnurri0.061
G-oalpha47AG protein oalpha 47A0.059
pimpimples0.057
E(spl)Enhancer of split0.057
Stat92ESignal-transducer and activator of transcription protein at 92E0.052
Fs(2)KetFemale sterile (2) Ketel0.052
ftz-f1ftz transcription factor 10.051
vasvasa0.051
Lis-1Lissencephaly-10.047
HLHm3E(spl) region transcript m30.047
rapretina aberrant in pattern0.046
JIL-1CG6297 gene product from transcript CG6297-RA0.046
S6kRPS6-p70-protein kinase0.046
cdc2CG5363 gene product from transcript CG5363-RA0.046
tkvthickveins0.045
Orc2Origin recognition complex subunit 20.045
emcextra macrochaetae0.041
pitaCG3941 gene product from transcript CG3941-RA0.041
Kr-h1Kruppel homolog 10.040
chbchromosome bows0.040
Tao-1CG14217 gene product from transcript CG14217-RF0.037
hthhomothorax0.036
latlatheo0.036
l(1)dd4lethal (1) discs degenerate 40.036
ovoCG6824 gene product from transcript CG6824-RE0.036
Syx1ASyntaxin 1A0.036
CG9772CG9772 gene product from transcript CG9772-RB0.035
sosine oculis0.035
stilstand still0.035
Cks85ACyclin-dependent kinase subunit 85A0.034
belbelle0.034
PvrPDGF- and VEGF-receptor related0.033
scribscribbled0.032
mod(mdg4)modifier of mdg40.032
rhirhino0.032
DNApol-alpha50DNA polymerase alpha 50kD0.031
CG11071CG11071 gene product from transcript CG11071-RA0.031
M6CG7540 gene product from transcript CG7540-RA0.030
ird5immune response deficient 50.030
escextra sexcombs0.030
Taspase1Taspase 10.029
BobABrother of Bearded A0.029
scscute0.029
CblCG7037 gene product from transcript CG7037-RB0.029
ranshiCG9793 gene product from transcript CG9793-RA0.029
Vsx2CG33980 gene product from transcript CG33980-RA0.028
par-1CG8201 gene product from transcript CG8201-RA0.028
Cul-5Cullin-50.028
quaquail0.027
ImpIGF-II mRNA-binding protein0.027
cidcentromere identifier0.027
Top1Topoisomerase 10.027
Cdc27CG8610 gene product from transcript CG8610-RA0.027
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.995
Ctnnb1catenin (cadherin associated protein), beta 10.946
Neurod1neurogenic differentiation 10.909
Shhsonic hedgehog0.884
Ptpn11protein tyrosine phosphatase, non-receptor type 110.869
CblCasitas B-lineage lymphoma0.834
Pax6paired box gene 60.750
Pax3paired box gene 30.729
Cdk2cyclin-dependent kinase 20.689
Ascl1achaete-scute complex homolog 1 (Drosophila)0.678
Notch2Notch gene homolog 2 (Drosophila)0.627
Pitx2paired-like homeodomain transcription factor 20.572
Gli3GLI-Kruppel family member GLI30.541
Tcf3transcription factor 30.508
Pkd1polycystic kidney disease 1 homolog0.461
Hand1heart and neural crest derivatives expressed transcript 10.452
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.446
Hoxd13homeobox D130.434
Hdac1histone deacetylase 10.389
Otx2orthodenticle homolog 2 (Drosophila)0.381
Sox2SRY-box containing gene 20.379
Rac1RAS-related C3 botulinum substrate 10.366
Plk1polo-like kinase 1 (Drosophila)0.358
Neurog2neurogenin 20.346
Cdk4cyclin-dependent kinase 40.336
Kdrkinase insert domain protein receptor0.326
Stag1stromal antigen 10.313
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.289
Gdf5growth differentiation factor 50.274
Hes1hairy and enhancer of split 1 (Drosophila)0.273
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.270
Ccnb1cyclin B10.264
Grb10growth factor receptor bound protein 100.263
Ccnd1cyclin D10.249
Hoxa13homeobox A130.249
Rb1retinoblastoma 10.241
Id1inhibitor of DNA binding 10.238
Alx4aristaless-like homeobox 40.237
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.237
Mdm2transformed mouse 3T3 cell double minute 20.234
Sox11SRY-box containing gene 110.232
Smad6MAD homolog 6 (Drosophila)0.232
Emx1empty spiracles homolog 1 (Drosophila)0.220
Adam17a disintegrin and metallopeptidase domain 170.220
Pthlhparathyroid hormone-like peptide0.215
Vegfavascular endothelial growth factor A0.209
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.198
Fgfr2fibroblast growth factor receptor 20.196
Nos3nitric oxide synthase 3, endothelial cell0.192
Dab1disabled homolog 1 (Drosophila)0.190
Tcf4transcription factor 40.186
Isl1ISL1 transcription factor, LIM/homeodomain0.185
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.184
Cdkn2acyclin-dependent kinase inhibitor 2A0.181
Lhx3LIM homeobox protein 30.179
Ccna2cyclin A20.172
Ccne1cyclin E10.172
Sox9SRY-box containing gene 90.171
Fgfr1fibroblast growth factor receptor 10.169
Ptf1apancreas specific transcription factor, 1a0.168
Gata4GATA binding protein 40.166
Csf1colony stimulating factor 1 (macrophage)0.165
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.163
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.153
Plcg1phospholipase C, gamma 10.152
Dkk1dickkopf homolog 1 (Xenopus laevis)0.152
Rag1recombination activating gene 10.150
Ptenphosphatase and tensin homolog0.148
Arid1aAT rich interactive domain 1A (SWI-like)0.147
Acanaggrecan0.146
Myf5myogenic factor 50.146
Pax7paired box gene 70.146
Brca1breast cancer 10.143
Tmpothymopoietin0.140
Onecut1one cut domain, family member 10.140
Id3inhibitor of DNA binding 30.135
Gab1growth factor receptor bound protein 2-associated protein 10.134
Wnt3awingless-related MMTV integration site 3A0.132
Axin1axin 10.131
Apcadenomatosis polyposis coli0.130
Ccnb2cyclin B20.128
Pou3f3POU domain, class 3, transcription factor 30.128
Mdm4transformed mouse 3T3 cell double minute 40.128
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.126
Lef1lymphoid enhancer binding factor 10.126
Foxc1forkhead box C10.126
Jag1jagged 10.124
Meox2mesenchyme homeobox 20.122
Ccnd2cyclin D20.122
Pax9paired box gene 90.119
Tbx3T-box 30.119
Bmp7bone morphogenetic protein 70.117
Lrp6low density lipoprotein receptor-related protein 60.116
Srsf2serine/arginine-rich splicing factor 20.115
Dnm1dynamin 10.115
Psen1presenilin 10.114
Gsk3bglycogen synthase kinase 3 beta0.112
En1engrailed 10.112
Wfikkn2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.110
H2afxH2A histone family, member X0.108
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CLB5Clb5p0.314
PFS1Pfs1p0.261
ARP8Arp8p0.236
RTS1Rts1p0.130
CTF4Ctf4p0.117
SIN3Sin3p0.104
VID24Vid24p0.100
CLB2Clb2p0.099
GLN3Gln3p0.099
CDC28Cdc28p0.094
BEM3Bem3p0.081
CKS1Cks1p0.080
MIG2Mig2p0.078
PDS1Pds1p0.076
CDH1Cdh1p0.075
CDC14Cdc14p0.067
TPK1Tpk1p0.065
RAD53Rad53p0.065
AFT1Aft1p0.062
NSE4Nse4p0.059
CDC20Cdc20p0.059
CDC6Cdc6p0.059
HHO1Hho1p0.059
GCR2Gcr2p0.058
HAL5Hal5p0.057
CLB1Clb1p0.056
YAK1Yak1p0.056
YPL014Whypothetical protein0.055
APC2Apc2p0.050
VHS1Vhs1p0.049
CLB3Clb3p0.049
PIN4Pin4p0.049
CSR2Csr2p0.048
PSP2Psp2p0.047
MIG3Mig3p0.047
ROX1Rox1p0.047
SLK19Slk19p0.046
YKR075Chypothetical protein0.046
MMS21Mms21p0.046
RAD54Rad54p0.046
MAD2Mad2p0.045
CDC16Cdc16p0.045
CSM1Csm1p0.044
PHM8Phm8p0.044
NSE1Nse1p0.043
HSL1Hsl1p0.043
CDC27Cdc27p0.043
VPS27Vps27p0.042
HXT3Hxt3p0.042
CBK1Cbk1p0.042
PRP45Prp45p0.041
TAO3Tao3p0.041
CLB6Clb6p0.040
CPR7Cpr7p0.040
MIG1Mig1p0.039
SAC7Sac7p0.038
HSF1Hsf1p0.038
RAD55Rad55p0.038
KCS1Kcs1p0.038
SLD3Sld3p0.037
PSF2Psf2p0.037
RFC5Rfc5p0.037
POG1Pog1p0.036
IRA1Ira1p0.036
IRC15Irc15p0.036
MCM4Mcm4p0.035
CDC4Cdc4p0.035
YDR506Chypothetical protein0.034
KRE29Kre29p0.033
APC4Apc4p0.033
CYR1Cyr1p0.033
CDC24Cdc24p0.033
SLG1Slg1p0.032
YLR297Whypothetical protein0.032
IES1Ies1p0.031
GAT2Gat2p0.031
MUS81Mus81p0.031
CAM1Cam1p0.030
SEC16Sec16p0.030
HST3Hst3p0.030
FKH2Fkh2p0.030
ATG29Atg29p0.029
VIK1Vik1p0.029
DCC1Dcc1p0.029
YKL187Chypothetical protein0.029
IML1Iml1p0.028
CLB4Clb4p0.028
ATG2Atg2p0.028
CAT8Cat8p0.028
TYE7Tye7p0.028
CHK1Chk1p0.028
YTA7Yta7p0.027
VMA4Vma4p0.027
NBL1Nbl1p0.027
ORC1Orc1p0.027
FKH1Fkh1p0.026
SWI5Swi5p0.026
CTI6Cti6p0.026
PBS2Pbs2p0.026
RAD7Rad7p0.026