The network for 'negative regulation of endothelial cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of endothelial cell development

Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.

NameDescriptionProbabilityFunc Analog Organism
TP63tumor protein p630.148
GFRA4GDNF family receptor alpha 40.080
HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 20.048
ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 20.045
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.034
NEUROD2neurogenic differentiation 20.033
CRHR2corticotropin releasing hormone receptor 20.032
RASGRP2RAS guanyl releasing protein 2 (calcium and DAG-regulated)0.031
RGS14regulator of G-protein signaling 140.031
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.029
NCR2natural cytotoxicity triggering receptor 20.027
FOXN1forkhead box N10.027
GRIA4glutamate receptor, ionotrophic, AMPA 40.027
PITPNM3PITPNM family member 30.026
CEACAM4carcinoembryonic antigen-related cell adhesion molecule 40.025
AVPR1Barginine vasopressin receptor 1B0.024
CHIAchitinase, acidic0.024
HBQ1hemoglobin, theta 10.023
GPR27G protein-coupled receptor 270.023
ZNF835zinc finger protein 8350.023
CD5CD5 molecule0.022
OLIG2oligodendrocyte lineage transcription factor 20.022
WNT1wingless-type MMTV integration site family, member 10.022
CD6CD6 molecule0.021
GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 10.021
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.020
P2RX2purinergic receptor P2X, ligand-gated ion channel, 20.020
GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 20.019
SLC30A3solute carrier family 30 (zinc transporter), member 30.019
PPAP2Bphosphatidic acid phosphatase type 2B0.019
TCL1BT-cell leukemia/lymphoma 1B0.019
ACAP1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.019
GPR12G protein-coupled receptor 120.018
TCL1AT-cell leukemia/lymphoma 1A0.018
CNTN2contactin 2 (axonal)0.018
GFRA3GDNF family receptor alpha 30.017
OPRL1opiate receptor-like 10.017
TNFSF8tumor necrosis factor (ligand) superfamily, member 80.017
FCHO1FCH domain only 10.017
CD7CD7 molecule0.017
JAK3Janus kinase 30.017
VPREB3pre-B lymphocyte 30.017
GJD2gap junction protein, delta 2, 36kDa0.017
P2RX1purinergic receptor P2X, ligand-gated ion channel, 10.016
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.016
LYL1lymphoblastic leukemia derived sequence 10.016
PDE6Gphosphodiesterase 6G, cGMP-specific, rod, gamma0.016
WNT7Awingless-type MMTV integration site family, member 7A0.016
FUT1fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)0.016
TKTL1transketolase-like 10.016
NXPH4neurexophilin 40.016
CEACAM3carcinoembryonic antigen-related cell adhesion molecule 30.016
KLF2Kruppel-like factor 2 (lung)0.016
DAB1disabled homolog 1 (Drosophila)0.015
GP1BAglycoprotein Ib (platelet), alpha polypeptide0.015
GRM6glutamate receptor, metabotropic 60.015
B3GNT4UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 40.014
TAC3tachykinin 30.014
PRODH2proline dehydrogenase (oxidase) 20.014
INAinternexin neuronal intermediate filament protein, alpha0.014
OPN1SWopsin 1 (cone pigments), short-wave-sensitive0.014
ICOSLGinducible T-cell co-stimulator ligand0.014
KIF17kinesin family member 170.014
CHIT1chitinase 1 (chitotriosidase)0.014
POU2F2POU class 2 homeobox 20.013
TRPM2transient receptor potential cation channel, subfamily M, member 20.013
ADAM11ADAM metallopeptidase domain 110.013
DENND1CDENN/MADD domain containing 1C0.013
CLCCharcot-Leyden crystal protein0.013
SLC22A14solute carrier family 22, member 140.013
SH2D3CSH2 domain containing 3C0.013
KCNA3potassium voltage-gated channel, shaker-related subfamily, member 30.013
RAB33ARAB33A, member RAS oncogene family0.013
POU3F1POU class 3 homeobox 10.013
CLEC1AC-type lectin domain family 1, member A0.013
STMN4stathmin-like 40.013
GPR15G protein-coupled receptor 150.013
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 20.013
RIC3resistance to inhibitors of cholinesterase 3 homolog (C. elegans)0.013
MC4Rmelanocortin 4 receptor0.013
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.013
FGF4fibroblast growth factor 40.012
GH2growth hormone 20.012
VSTM2AV-set and transmembrane domain containing 2A0.012
ARHGDIGRho GDP dissociation inhibitor (GDI) gamma0.012
COLEC12collectin sub-family member 120.012
MYL4myosin, light chain 4, alkali; atrial, embryonic0.012
CA6carbonic anhydrase VI0.012
GRAPGRB2-related adaptor protein0.012
NPYneuropeptide Y0.012
IL19interleukin 190.012
RLBP1retinaldehyde binding protein 10.012
GPR97G protein-coupled receptor 970.012
TRPM8transient receptor potential cation channel, subfamily M, member 80.012
GIMAP7GTPase, IMAP family member 70.012
HTR1A5-hydroxytryptamine (serotonin) receptor 1A0.012
KCNA2potassium voltage-gated channel, shaker-related subfamily, member 20.012
CXCR1chemokine (C-X-C motif) receptor 10.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism