The network for 'positive regulation of transcription from rna polymerase ii promoter involved in heart development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of transcription from rna polymerase ii promoter involved in heart development

Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.

NameDescriptionProbabilityFunc Analog Organism
SRFserum response factor (c-fos serum response element-binding transcription factor)1.000
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.999
MKL1megakaryoblastic leukemia (translocation) 10.984
BTF3basic transcription factor 30.971
MYOGmyogenin (myogenic factor 4)0.930
MYOD1myogenic differentiation 10.904
SMAD1SMAD family member 10.853
GATA4GATA binding protein 40.748
FUNDC2FUN14 domain containing 20.558
EIF3Heukaryotic translation initiation factor 3, subunit H0.455
NCOR2nuclear receptor corepressor 20.455
MKL2MKL/myocardin-like 20.367
NSA2NSA2 ribosome biogenesis homolog (S. cerevisiae)0.270
EIF3Eeukaryotic translation initiation factor 3, subunit E0.152
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.144
RPL36ALribosomal protein L36a-like0.128
RPL34ribosomal protein L340.079
SMAD7SMAD family member 70.070
TBX1T-box 10.054
RPL36Aribosomal protein L36a0.048
SOX18SRY (sex determining region Y)-box 180.045
TBX5T-box 50.044
SMAD6SMAD family member 60.043
PMLpromyelocytic leukemia0.042
ARandrogen receptor0.040
GATA5GATA binding protein 50.039
FOXF1forkhead box F10.039
TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor)0.037
SMURF1SMAD specific E3 ubiquitin protein ligase 10.034
MSX1msh homeobox 10.033
PYYpeptide YY0.033
FGF8fibroblast growth factor 8 (androgen-induced)0.031
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.029
SMAD4SMAD family member 40.027
ZHX1zinc fingers and homeoboxes 10.027
NSFN-ethylmaleimide-sensitive factor0.027
ARL15ADP-ribosylation factor-like 150.027
LBX1ladybird homeobox 10.026
IL2RBinterleukin 2 receptor, beta0.026
RPL26ribosomal protein L260.023
RPL17ribosomal protein L170.022
HOXD12homeobox D120.021
COL13A1collagen, type XIII, alpha 10.021
HOXD9homeobox D90.021
COL2A1collagen, type II, alpha 10.020
FGF3fibroblast growth factor 30.019
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.019
ASCC2activating signal cointegrator 1 complex subunit 20.019
CXCR6chemokine (C-X-C motif) receptor 60.018
BANPBTG3 associated nuclear protein0.017
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.017
SOX1SRY (sex determining region Y)-box 10.017
FOXE1forkhead box E1 (thyroid transcription factor 2)0.017
FGF18fibroblast growth factor 180.017
PABPC3poly(A) binding protein, cytoplasmic 30.017
HOXB13homeobox B130.017
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.017
PPARAperoxisome proliferator-activated receptor alpha0.016
HOXC11homeobox C110.016
USP13ubiquitin specific peptidase 13 (isopeptidase T-3)0.016
RPL35Aribosomal protein L35a0.016
KIR3DL2killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 20.016
VAX2ventral anterior homeobox 20.016
FOXF2forkhead box F20.016
EGR1early growth response 10.016
NFYAnuclear transcription factor Y, alpha0.015
SIX2SIX homeobox 20.015
LTKleukocyte receptor tyrosine kinase0.015
YAP1Yes-associated protein 10.015
IKZF3IKAROS family zinc finger 3 (Aiolos)0.015
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.015
ZNF33Bzinc finger protein 33B0.015
ELK1ELK1, member of ETS oncogene family0.015
DLL4delta-like 4 (Drosophila)0.015
NKX2-8NK2 homeobox 80.014
MYH6myosin, heavy chain 6, cardiac muscle, alpha0.014
COMPcartilage oligomeric matrix protein0.014
CSPG4chondroitin sulfate proteoglycan 40.014
GATA2GATA binding protein 20.014
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.014
CD7CD7 molecule0.014
EEF1B2eukaryotic translation elongation factor 1 beta 20.014
HOXA11homeobox A110.014
GTF2Igeneral transcription factor IIi0.014
PFDN5prefoldin subunit 50.014
RPL41ribosomal protein L410.014
PGRprogesterone receptor0.013
GNG11guanine nucleotide binding protein (G protein), gamma 110.013
NEDD9neural precursor cell expressed, developmentally down-regulated 90.013
HOXC8homeobox C80.013
DLX4distal-less homeobox 40.013
IRX5iroquois homeobox 50.013
FOXL1forkhead box L10.013
GATA3GATA binding protein 30.013
HOXD11homeobox D110.013
TBX2T-box 20.013
KLHL35kelch-like 35 (Drosophila)0.013
CHRDL2chordin-like 20.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pitx2paired-like homeodomain transcription factor 21.000
Fgfr2fibroblast growth factor receptor 20.999
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.999
Pax3paired box gene 30.996
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.995
Pax2paired box gene 20.993
Tbx3T-box 30.991
Fgf8fibroblast growth factor 80.990
Hoxa1homeobox A10.990
Eya1eyes absent 1 homolog (Drosophila)0.990
Chd7chromodomain helicase DNA binding protein 70.987
Otx2orthodenticle homolog 2 (Drosophila)0.986
Hand2heart and neural crest derivatives expressed transcript 20.985
Foxc1forkhead box C10.984
Bmp4bone morphogenetic protein 40.982
Foxc2forkhead box C20.982
Pitx1paired-like homeodomain transcription factor 10.982
Gli3GLI-Kruppel family member GLI30.981
Dlx5distal-less homeobox 50.979
Msx1homeobox, msh-like 10.979
Foxg1forkhead box G10.977
Tcfap2atranscription factor AP-2, alpha0.973
Prrx1paired related homeobox 10.958
Hand1heart and neural crest derivatives expressed transcript 10.954
Sox9SRY-box containing gene 90.928
Tbx5T-box 50.920
Scn5asodium channel, voltage-gated, type V, alpha0.885
Sall4sal-like 4 (Drosophila)0.875
Fgfr1fibroblast growth factor receptor 10.866
Fgf10fibroblast growth factor 100.856
Msx2homeobox, msh-like 20.826
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.814
Rargretinoic acid receptor, gamma0.798
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.762
Isl1ISL1 transcription factor, LIM/homeodomain0.750
Hoxa3homeobox A30.746
Rarbretinoic acid receptor, beta0.734
Tbx1T-box 10.732
Gbx2gastrulation brain homeobox 20.673
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.654
Gscgoosecoid homeobox0.651
Gja5gap junction protein, alpha 50.645
Vangl2vang-like 2 (van gogh, Drosophila)0.620
Runx2runt related transcription factor 20.613
Wt1Wilms tumor 1 homolog0.596
Prrx2paired related homeobox 20.581
Jag1jagged 10.573
Gata4GATA binding protein 40.560
Bmp7bone morphogenetic protein 70.548
Pax9paired box gene 90.498
Hoxa2homeobox A20.498
Zic3zinc finger protein of the cerebellum 30.496
Lhx1LIM homeobox protein 10.482
Efnb2ephrin B20.467
Hoxd11homeobox D110.461
Ror2receptor tyrosine kinase-like orphan receptor 20.453
Tbx4T-box 40.447
Lef1lymphoid enhancer binding factor 10.430
Sox2SRY-box containing gene 20.397
Zeb1zinc finger E-box binding homeobox 10.390
Lmx1aLIM homeobox transcription factor 1 alpha0.378
Lrp6low density lipoprotein receptor-related protein 60.375
Fgfr3fibroblast growth factor receptor 30.373
Smosmoothened homolog (Drosophila)0.372
Twist2twist homolog 2 (Drosophila)0.365
Gli2GLI-Kruppel family member GLI20.352
Vegfavascular endothelial growth factor A0.351
Rxraretinoid X receptor alpha0.329
Wnt3awingless-related MMTV integration site 3A0.322
Tcf21transcription factor 210.320
Otx1orthodenticle homolog 1 (Drosophila)0.312
Hoxa11homeobox A110.308
Hoxd3homeobox D30.304
Pou5f1POU domain, class 5, transcription factor 10.303
Ednraendothelin receptor type A0.302
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.298
Alx1ALX homeobox 10.285
Hoxa13homeobox A130.282
Sall1sal-like 1 (Drosophila)0.273
Tgfb2transforming growth factor, beta 20.237
Pbx1pre B-cell leukemia transcription factor 10.225
NanogNanog homeobox0.225
Hmx3H6 homeobox 30.224
Ighmbp2immunoglobulin mu binding protein 20.219
Gata6GATA binding protein 60.207
Rararetinoic acid receptor, alpha0.199
Gata3GATA binding protein 30.194
Sox11SRY-box containing gene 110.188
Pcsk5proprotein convertase subtilisin/kexin type 50.180
Dlx2distal-less homeobox 20.177
Mesp1mesoderm posterior 10.168
Fgf3fibroblast growth factor 30.162
Hoxd13homeobox D130.150
Trp63transformation related protein 630.149
Ptpn11protein tyrosine phosphatase, non-receptor type 110.146
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism