The network for 'kidney vasculature development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

kidney vasculature development

The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
VEGFAvascular endothelial growth factor A0.999
JAG1jagged 10.995
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.970
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.954
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.762
CFL1cofilin 1 (non-muscle)0.681
BMPR1Abone morphogenetic protein receptor, type IA0.636
NOTCH1notch 10.578
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.494
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.483
NOTCH3notch 30.430
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.360
TEKTEK tyrosine kinase, endothelial0.298
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.275
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.193
BMPR1Bbone morphogenetic protein receptor, type IB0.188
NRP1neuropilin 10.172
MYH11myosin, heavy chain 11, smooth muscle0.146
CFL2cofilin 2 (muscle)0.101
PKD1polycystic kidney disease 1 (autosomal dominant)0.097
PTPRBprotein tyrosine phosphatase, receptor type, B0.066
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.053
CAV1caveolin 1, caveolae protein, 22kDa0.051
DLL1delta-like 1 (Drosophila)0.049
SNAI1snail homolog 1 (Drosophila)0.049
NR4A1nuclear receptor subfamily 4, group A, member 10.043
BMP4bone morphogenetic protein 40.040
PGFplacental growth factor0.038
TPM1tropomyosin 1 (alpha)0.038
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.038
TRPC1transient receptor potential cation channel, subfamily C, member 10.037
PDGFCplatelet derived growth factor C0.035
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.035
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.035
PDGFAplatelet-derived growth factor alpha polypeptide0.032
PLCG1phospholipase C, gamma 10.025
TAOK1TAO kinase 10.023
EGR3early growth response 30.022
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.022
ANGPT2angiopoietin 20.021
ZFYVE9zinc finger, FYVE domain containing 90.021
IER2immediate early response 20.021
DVL3dishevelled, dsh homolog 3 (Drosophila)0.018
EGR2early growth response 20.017
COL2A1collagen, type II, alpha 10.017
JAG2jagged 20.016
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.016
TRIM63tripartite motif containing 630.015
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.015
PTGISprostaglandin I2 (prostacyclin) synthase0.013
CNN2calponin 20.012
STC1stanniocalcin 10.012
CD93CD93 molecule0.011
BBS10Bardet-Biedl syndrome 100.011
COL6A1collagen, type VI, alpha 10.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
osr2odd-skipped related 2 (Drosophila)0.995
kdrlkinase insert domain receptor like0.981
bmp2bbone morphogenetic protein 2b0.935
sox9aSRY-box containing gene 9a0.839
wt1awilms tumor 1a0.754
tbx5aT-box 5a0.750
hnf1baHNF1 homeobox Ba0.703
cdh2cadherin 2, neuronal0.644
aldh1a2aldehyde dehydrogenase 1 family, member A20.620
hand2heart and neural crest derivatives expressed transcript 20.555
mibmind bomb0.538
fli1afriend leukemia integration 1a0.473
notch1anotch homolog 1a0.439
foxc1aforkhead box C1a0.319
jag1bjagged 1b0.289
mecomMDS1 and EVI1 complex locus0.274
osr1odd-skipped related 1 (Drosophila)0.270
bmp4bone morphogenetic protein 40.267
tbx1T-box 10.264
jag2jagged 20.255
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.245
wt1bwilms tumor 1b0.241
aqp8a.1aquaporin 8a, tandem duplicate 10.229
myod1myogenic differentiation 10.217
ptgs1prostaglandin-endoperoxide synthase 10.177
neo1neogenin 10.173
wnt9awingless-type MMTV integration site family, member 9A0.163
hnf1bbHNF1 homeobox Bb0.132
cmybtranscription factor cmyb0.121
hhexhematopoietically expressed homeobox0.109
wnt2bbwingless-type MMTV integration site family, member 2Bb0.096
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.094
rereaarginine-glutamic acid dipeptide (RE) repeats a0.092
restRE1-silencing transcription factor0.090
aplnrbapelin receptor b0.088
foxa3forkhead box A30.086
cdh5cadherin 50.086
gja3gap junction protein, alpha 30.086
col2a1acollagen type II, alpha-1a0.084
tgfb3transforming growth factor, beta 30.083
foxj1aforkhead box J1a0.083
nrp1aneuropilin 1a0.075
klf4aKruppel-like transcription factor 4a0.073
vegfaavascular endothelial growth factor Aa0.068
krt4keratin 40.067
vegfcvascular endothelial growth factor c0.066
tfectranscription factor EC0.062
cx27.5connexin 27.50.062
gata1aGATA binding protein 1a0.062
ednraendothelin receptor type A0.061
cyp1b1cytochrome P450, family 1, subfamily B, polypeptide 10.060
sim1asingle-minded homolog 1a (Drosophila)0.060
lmx1b.1LIM homeobox transcription factor 1, beta 10.055
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.055
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.055
lrrc50leucine rich repeat containing 500.052
slc4a4asolute carrier family 4, member 4a0.049
plcg1phospholipase C, gamma 10.049
nrp2aneuropilin 2a0.049
per2period homolog 2 (Drosophila)0.048
runx3runt-related transcription factor 30.047
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.046
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.045
etv2ets variant gene 20.044
trpv4transient receptor potential cation channel, subfamily V, member 40.042
jam2bjunctional adhesion molecule 2b0.042
tll1tolloid-like 10.042
hoxa13ahomeo box A13a0.042
fstl1afollistatin-like 1a0.041
pcdh8protocadherin 80.041
satb2SATB homeobox 20.040
leprleptin receptor0.040
crb2acrumbs homolog 2a0.039
edn1endothelin 10.039
mpxmyeloid-specific peroxidase0.038
hey1hairy/enhancer-of-split related with YRPW motif 10.038
foxc1bforkhead box C1b0.037
vangl2vang-like 2 (van gogh, Drosophila)0.037
nkx2.3NK2 transcription factor related 30.036
klf2aKruppel-like factor 2a0.036
igf2binsulin-like growth factor 2b0.036
tbx22T-box 220.034
ptch1patched 10.034
tgfb2transforming growth factor, beta 20.034
brd2abromodomain-containing 2a0.034
emp2epithelial membrane protein 20.034
sema3hsemaphorin 3h0.034
hbae1hemoglobin alpha embryonic-10.033
tbx5bT-box 5b0.033
slit3slit (Drosophila) homolog 30.033
lmnalamin A0.032
gdnfglial cell derived neurotrophic factor0.031
adra2badrenergic, alpha-2B-, receptor0.031
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Kdrkinase insert domain protein receptor0.994
Vegfavascular endothelial growth factor A0.992
Shhsonic hedgehog0.989
Ctnnb1catenin (cadherin associated protein), beta 10.969
Tbx1T-box 10.959
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.926
Flt4FMS-like tyrosine kinase 40.905
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.902
Otx2orthodenticle homolog 2 (Drosophila)0.800
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.776
Bcl2B-cell leukemia/lymphoma 20.740
Nos3nitric oxide synthase 3, endothelial cell0.728
Meox2mesenchyme homeobox 20.681
Emx2empty spiracles homolog 2 (Drosophila)0.655
Fgfr2fibroblast growth factor receptor 20.650
Wt1Wilms tumor 1 homolog0.643
Foxa2forkhead box A20.587
Nkx2-1NK2 homeobox 10.581
Ptprbprotein tyrosine phosphatase, receptor type, B0.548
Msx1homeobox, msh-like 10.539
Gli3GLI-Kruppel family member GLI30.487
Notch2Notch gene homolog 2 (Drosophila)0.471
Pax2paired box gene 20.423
Csf1colony stimulating factor 1 (macrophage)0.416
Fgfr1fibroblast growth factor receptor 10.414
Dll1delta-like 1 (Drosophila)0.396
Cdh5cadherin 50.372
Tgfb2transforming growth factor, beta 20.371
Hand2heart and neural crest derivatives expressed transcript 20.369
Fgf8fibroblast growth factor 80.359
Bmp4bone morphogenetic protein 40.354
Itgb1integrin beta 1 (fibronectin receptor beta)0.345
Foxc2forkhead box C20.342
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.333
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.318
Otx1orthodenticle homolog 1 (Drosophila)0.316
Gata6GATA binding protein 60.303
Gdnfglial cell line derived neurotrophic factor0.302
Col4a3collagen, type IV, alpha 30.290
Flt1FMS-like tyrosine kinase 10.285
Sox18SRY-box containing gene 180.284
Lmx1bLIM homeobox transcription factor 1 beta0.283
Emx1empty spiracles homolog 1 (Drosophila)0.267
Ptenphosphatase and tensin homolog0.266
Tcf21transcription factor 210.261
Tgfbr2transforming growth factor, beta receptor II0.240
Cxcl12chemokine (C-X-C motif) ligand 120.236
Sox17SRY-box containing gene 170.223
Nab2Ngfi-A binding protein 20.220
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.213
FosFBJ osteosarcoma oncogene0.207
Lhx1LIM homeobox protein 10.190
Foxc1forkhead box C10.184
Hes1hairy and enhancer of split 1 (Drosophila)0.173
Pbx1pre B-cell leukemia transcription factor 10.164
Leprleptin receptor0.163
Runx2runt related transcription factor 20.159
Pdgfbplatelet derived growth factor, B polypeptide0.130
Shesrc homology 2 domain-containing transforming protein E0.122
Hmx3H6 homeobox 30.111
Smad6MAD homolog 6 (Drosophila)0.109
Ptgs2prostaglandin-endoperoxide synthase 20.107
Prrx1paired related homeobox 10.104
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.103
JunJun oncogene0.100
Tekendothelial-specific receptor tyrosine kinase0.099
Hes5hairy and enhancer of split 5 (Drosophila)0.098
Psen1presenilin 10.097
Acvrl1activin A receptor, type II-like 10.094
Jag1jagged 10.088
Tlx3T-cell leukemia, homeobox 30.085
Pax8paired box gene 80.084
Sox7SRY-box containing gene 70.080
Hand1heart and neural crest derivatives expressed transcript 10.080
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.077
Nfibnuclear factor I/B0.075
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.074
Lama5laminin, alpha 50.073
Nr2f2nuclear receptor subfamily 2, group F, member 20.072
Tbx2T-box 20.063
Ror2receptor tyrosine kinase-like orphan receptor 20.063
Egfl7EGF-like domain 70.061
Efnb2ephrin B20.060
Ddr2discoidin domain receptor family, member 20.060
Pax6paired box gene 60.059
Gas1growth arrest specific 10.058
Hes3hairy and enhancer of split 3 (Drosophila)0.058
Foxh1forkhead box H10.058
Egr1early growth response 10.056
Npr3natriuretic peptide receptor 30.056
Cd151CD151 antigen0.056
Ascl1achaete-scute complex homolog 1 (Drosophila)0.055
Tdgf1teratocarcinoma-derived growth factor 10.055
En1engrailed 10.054
Cldn5claudin 50.053
Smad3MAD homolog 3 (Drosophila)0.052
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Egr1early growth response 10.474
Egr2early growth response 20.455
Nfibnuclear factor I/B0.245
FosFBJ osteosarcoma oncogene0.225
Dusp6dual specificity phosphatase 60.172
Ddr2discoidin domain receptor tyrosine kinase 20.132
Wipf1WAS/WASL interacting protein family, member 10.131
Junbjun B proto-oncogene0.117
Egr3early growth response 30.099
Sod3superoxide dismutase 3, extracellular0.064
Il6interleukin 60.056
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.052
Clca5chloride channel calcium activated 50.046
Adh6aalcohol dehydrogenase 6A (class V)0.045
Fbln1fibulin 10.043
Gpc3glypican 30.042
Serpinb3serine protease inhibitor B30.040
Nr4a1nuclear receptor subfamily 4, group A, member 10.035
Col1a2collagen, type I, alpha 20.032
Foxs1forkhead box S10.032
Aebp1AE binding protein 10.031
Ccl6chemokine (C-C motif) ligand 60.028
Prelpproline/arginine-rich end leucine-rich repeat protein0.027
Cpxm1carboxypeptidase X (M14 family), member 10.026
Nos3nitric oxide synthase 3, endothelial cell0.026
Ptpn18protein tyrosine phosphatase, non-receptor type 180.026
Twist2twist homolog 2 (Drosophila)0.024
Anxa4annexin A40.023
Plac8placenta-specific 80.021
Gpr20G protein-coupled receptor 200.021
C4bcomplement component 4B (Chido blood group)0.018
Ltbp4latent transforming growth factor beta binding protein 40.018
Pxdnperoxidasin homolog (Drosophila)0.017
Cst7cystatin F (leukocystatin)0.017
Col5a1collagen, type V, alpha 10.016
Vwfvon Willebrand factor0.016
Lamb2laminin, beta 20.016
Fgafibrinogen alpha chain0.015
Add3adducin 3 (gamma)0.015
Loxl1lysyl oxidase-like 10.015
C1qtnf1C1q and tumor necrosis factor related protein 10.014
Lgals7lectin, galactoside-binding, soluble, 70.014
F13a1coagulation factor XIII, A1 polypeptide0.014
Myd88myeloid differentiation primary response gene 880.013
Igfbp7insulin-like growth factor binding protein 70.013
Il13ra1interleukin 13 receptor, alpha 10.013
C7complement component 70.011
Plauplasminogen activator, urokinase0.011
Cd4Cd4 molecule0.010
Htra3HtrA serine peptidase 30.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism