The network for 'positive regulation of calcium mediated signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of calcium mediated signaling

Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.

NameDescriptionProbabilityFunc Analog Organism
Ascl1achaete-scute complex homolog 1 (Drosophila)0.854
Neurod1neurogenic differentiation 10.685
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.587
Cd8aCD8 antigen, alpha chain0.563
Lcklymphocyte protein tyrosine kinase0.531
Inpp5dinositol polyphosphate-5-phosphatase D0.524
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.446
MecomMDS1 and EVI1 complex locus0.401
Cd4CD4 antigen0.373
Cd7CD7 antigen0.312
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.298
MefvMediterranean fever0.289
Pax6paired box gene 60.278
Cd247CD247 antigen0.258
Il2rginterleukin 2 receptor, gamma chain0.253
Neurog2neurogenin 20.231
Itgalintegrin alpha L0.226
Ptprcprotein tyrosine phosphatase, receptor type, C0.219
Neurod4neurogenic differentiation 40.201
Timp1tissue inhibitor of metalloproteinase 10.191
Aif1allograft inflammatory factor 10.179
AF251705cDNA sequence AF2517050.179
Prnpprion protein0.149
BC013712cDNA sequence BC0137120.125
TyrobpTYRO protein tyrosine kinase binding protein0.114
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.114
Lair1leukocyte-associated Ig-like receptor 10.111
Cd22CD22 antigen0.109
Tbxas1thromboxane A synthase 1, platelet0.105
ItkIL2-inducible T-cell kinase0.105
Nr5a1nuclear receptor subfamily 5, group A, member 10.103
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.101
Madcam1mucosal vascular addressin cell adhesion molecule 10.097
Cxcr3chemokine (C-X-C motif) receptor 30.095
Cd8b1CD8 antigen, beta chain 10.092
C3ar1complement component 3a receptor 10.088
Csf1rcolony stimulating factor 1 receptor0.088
Lcp2lymphocyte cytosolic protein 20.086
Isl1ISL1 transcription factor, LIM/homeodomain0.085
Rhohras homolog gene family, member H0.084
FaslFas ligand (TNF superfamily, member 6)0.077
Itgb1integrin beta 1 (fibronectin receptor beta)0.074
Snai1snail homolog 1 (Drosophila)0.074
Insm1insulinoma-associated 10.073
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.072
Il4interleukin 40.071
Nfam1Nfat activating molecule with ITAM motif 10.067
Cd28CD28 antigen0.066
Ncf1neutrophil cytosolic factor 10.066
Ciitaclass II transactivator0.064
Hckhemopoietic cell kinase0.064
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.063
Tgfb2transforming growth factor, beta 20.062
Ccr1chemokine (C-C motif) receptor 10.062
Batf3basic leucine zipper transcription factor, ATF-like 30.060
WasWiskott-Aldrich syndrome homolog (human)0.058
Nos3nitric oxide synthase 3, endothelial cell0.058
Kitkit oncogene0.058
Clec4eC-type lectin domain family 4, member e0.057
Hcsthematopoietic cell signal transducer0.056
Gata1GATA binding protein 10.054
Slc11a1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.053
Cd3eCD3 antigen, epsilon polypeptide0.053
Neurog3neurogenin 30.052
Pcdh12protocadherin 120.051
Dok3docking protein 30.050
Myo1fmyosin IF0.049
Sox11SRY-box containing gene 110.048
Gpr132G protein-coupled receptor 1320.048
Sh2d2aSH2 domain protein 2A0.048
Trem3triggering receptor expressed on myeloid cells 30.047
Dok2docking protein 20.047
Cst7cystatin F (leukocystatin)0.046
Cd244CD244 natural killer cell receptor 2B40.046
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.046
Kiss1KiSS-1 metastasis-suppressor0.046
Batfbasic leucine zipper transcription factor, ATF-like0.045
Pdcd1programmed cell death 10.043
Otx2orthodenticle homolog 2 (Drosophila)0.043
Arhgap9Rho GTPase activating protein 90.042
Gli2GLI-Kruppel family member GLI20.042
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.042
Tgfbr2transforming growth factor, beta receptor II0.042
Sept1septin 10.042
Cd19CD19 antigen0.041
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.040
Cx3cr1chemokine (C-X3-C) receptor 10.040
Itgaxintegrin alpha X0.040
Tcf21transcription factor 210.040
Ptpn11protein tyrosine phosphatase, non-receptor type 110.039
Mab21l2mab-21-like 2 (C. elegans)0.038
Mmp8matrix metallopeptidase 80.038
Sfpi1SFFV proviral integration 10.038
Klrg1killer cell lectin-like receptor subfamily G, member 10.038
Fesfeline sarcoma oncogene0.037
Cxcr2chemokine (C-X-C motif) receptor 20.037
Rap2bRAP2B, member of RAS oncogene family0.037
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.037
Gpsm3G-protein signalling modulator 3 (AGS3-like, C. elegans)0.036
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
LCKlymphocyte-specific protein tyrosine kinase0.998
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.908
CD247CD247 molecule0.873
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.832
PTPRCprotein tyrosine phosphatase, receptor type, C0.815
SYKspleen tyrosine kinase0.563
CCR5chemokine (C-C motif) receptor 50.531
LATlinker for activation of T cells0.484
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.125
PTPN22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.096
DSG2desmoglein 20.096
CCL2chemokine (C-C motif) ligand 20.092
CD2CD2 molecule0.064
CCL4chemokine (C-C motif) ligand 40.063
CTNND1catenin (cadherin-associated protein), delta 10.052
ITGB1BP3integrin beta 1 binding protein 30.050
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.042
IL8interleukin 80.041
CCL8chemokine (C-C motif) ligand 80.039
VAV1vav 1 guanine nucleotide exchange factor0.038
CCL5chemokine (C-C motif) ligand 50.032
CCR7chemokine (C-C motif) receptor 70.031
CCL13chemokine (C-C motif) ligand 130.030
DPP4dipeptidyl-peptidase 40.025
CD3DCD3d molecule, delta (CD3-TCR complex)0.025
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.023
CXCL13chemokine (C-X-C motif) ligand 130.022
IFNGinterferon, gamma0.022
SH2D1ASH2 domain containing 1A0.021
CXCL9chemokine (C-X-C motif) ligand 90.021
IDEinsulin-degrading enzyme0.020
CCL3chemokine (C-C motif) ligand 30.019
SH2D2ASH2 domain containing 2A0.018
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.018
CD8BCD8b molecule0.018
MMP12matrix metallopeptidase 12 (macrophage elastase)0.018
CD3GCD3g molecule, gamma (CD3-TCR complex)0.018
CXCL3chemokine (C-X-C motif) ligand 30.017
CXCL2chemokine (C-X-C motif) ligand 20.017
HMG20Ahigh mobility group 20A0.015
IL6interleukin 6 (interferon, beta 2)0.015
IGF2Rinsulin-like growth factor 2 receptor0.015
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.014
ICAM1intercellular adhesion molecule 10.013
PRKCQprotein kinase C, theta0.013
IL2RBinterleukin 2 receptor, beta0.013
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.012
IL1Binterleukin 1, beta0.012
UBASH3Bubiquitin associated and SH3 domain containing B0.011
TNFtumor necrosis factor0.011
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.011
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.011
CCR4chemokine (C-C motif) receptor 40.011
WASLWiskott-Aldrich syndrome-like0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism