The network for 'negative regulation of nitric oxide synthase biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of nitric oxide synthase biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.

NameDescriptionProbabilityFunc Analog Organism
Gstm1glutathione S-transferase, mu 10.825
Ces1dcarboxylesterase 1D0.447
Tmem205transmembrane protein 2050.401
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.398
Gm3776predicted gene 37760.337
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.287
Atp5dATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit0.255
Gstt1glutathione S-transferase, theta 10.230
Pgls6-phosphogluconolactonase0.154
Gsta2glutathione S-transferase, alpha 2 (Yc2)0.128
Cbr1carbonyl reductase 10.124
Ednraendothelin receptor type A0.124
Adh1alcohol dehydrogenase 1 (class I)0.089
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.087
Gsta4glutathione S-transferase, alpha 40.075
Ednrbendothelin receptor type B0.065
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.053
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.052
Inmtindolethylamine N-methyltransferase0.051
Gsta3glutathione S-transferase, alpha 30.050
Trpv4transient receptor potential cation channel, subfamily V, member 40.048
Apoc1apolipoprotein C-I0.043
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.042
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.033
Edf1endothelial differentiation-related factor 10.033
Mpzl2myelin protein zero-like 20.033
Selenbp1selenium binding protein 10.032
Ece1endothelin converting enzyme 10.030
Sult1d1sulfotransferase family 1D, member 10.030
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.029
Gstk1glutathione S-transferase kappa 10.027
Gstm6glutathione S-transferase, mu 60.026
Gstm2glutathione S-transferase, mu 20.025
Aassaminoadipate-semialdehyde synthase0.024
Rbp4retinol binding protein 4, plasma0.021
Eci1enoyl-Coenzyme A delta isomerase 10.019
Prdx6peroxiredoxin 60.019
Pirpirin0.019
Cyb5cytochrome b-50.017
Sordsorbitol dehydrogenase0.017
Gstm3glutathione S-transferase, mu 30.017
Gsto1glutathione S-transferase omega 10.016
Aox1aldehyde oxidase 10.016
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.015
Hint2histidine triad nucleotide binding protein 20.015
Chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.015
BC004004cDNA sequence BC0040040.014
Grhprglyoxylate reductase/hydroxypyruvate reductase0.013
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.013
Nqo1NAD(P)H dehydrogenase, quinone 10.013
Cmblcarboxymethylenebutenolidase-like (Pseudomonas)0.012
Ces1gcarboxylesterase 1G0.012
Ndufv3NADH dehydrogenase (ubiquinone) flavoprotein 30.012
Gpx4glutathione peroxidase 40.012
Fxyd1FXYD domain-containing ion transport regulator 10.011
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.011
Ces1ecarboxylesterase 1E0.011
Pon1paraoxonase 10.011
Ephx1epoxide hydrolase 1, microsomal0.010
Slc25a39solute carrier family 25, member 390.010
Fmo1flavin containing monooxygenase 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
DERL1Der1-like domain family, member 10.331
HERPUD1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 10.076
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.023
VCPvalosin containing protein0.015
MANFmesencephalic astrocyte-derived neurotrophic factor0.013
SLC35B1solute carrier family 35, member B10.013
DERL2Der1-like domain family, member 20.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gtf2bgeneral transcription factor IIB0.014
Polr2gpolymerase (RNA) II (DNA directed) polypeptide G0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism