The network for 'guanosine containing compound catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

guanosine containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).

NameDescriptionProbabilityFunc Analog Organism
Epha4Eph receptor A40.996
Grb2growth factor receptor bound protein 20.986
Rac1RAS-related C3 botulinum substrate 10.980
Itsn1intersectin 1 (SH3 domain protein 1A)0.971
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.964
Efnb2ephrin B20.950
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.945
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.931
BrafBraf transforming gene0.910
Arrb2arrestin, beta 20.893
Ntf3neurotrophin 30.881
Bcl2B-cell leukemia/lymphoma 20.870
Plxna1plexin A10.852
Plxnb1plexin B10.841
Parvaparvin, alpha0.817
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.807
Dock1dedicator of cytokinesis 10.799
Igtpinterferon gamma induced GTPase0.798
Git1G protein-coupled receptor kinase-interactor 10.793
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.778
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.764
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.758
CblCasitas B-lineage lymphoma0.700
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.699
Spry2sprouty homolog 2 (Drosophila)0.697
Mapkap1mitogen-activated protein kinase associated protein 10.670
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.649
Spry4sprouty homolog 4 (Drosophila)0.641
Pxnpaxillin0.623
Vav1vav 1 oncogene0.622
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.622
Selplgselectin, platelet (p-selectin) ligand0.620
Drd2dopamine receptor D20.613
Eea1early endosome antigen 10.599
RgnefRho-guanine nucleotide exchange factor0.592
Gbp2guanylate binding protein 20.564
Ilkintegrin linked kinase0.560
Fscn1fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)0.559
Tmem30atransmembrane protein 30A0.559
Ptk2bPTK2 protein tyrosine kinase 2 beta0.553
BaxBCL2-associated X protein0.553
Plcg1phospholipase C, gamma 10.550
Ccl2chemokine (C-C motif) ligand 20.546
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.541
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.541
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.541
Prkccprotein kinase C, gamma0.538
Plxna3plexin A30.531
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.529
Ephb4Eph receptor B40.521
Cd44CD44 antigen0.521
Sox10SRY-box containing gene 100.507
Iigp1interferon inducible GTPase 10.501
Pik3cbphosphatidylinositol 3-kinase, catalytic, beta polypeptide0.498
Pdgfbplatelet derived growth factor, B polypeptide0.493
Rtknrhotekin0.490
Rasgrp1RAS guanyl releasing protein 10.485
Epha1Eph receptor A10.482
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.479
Chrm1cholinergic receptor, muscarinic 1, CNS0.475
Vaspvasodilator-stimulated phosphoprotein0.467
Tsc1tuberous sclerosis 10.466
Ccr2chemokine (C-C motif) receptor 20.454
Fgfr3fibroblast growth factor receptor 30.449
Uba3ubiquitin-like modifier activating enzyme 30.446
Ptpn13protein tyrosine phosphatase, non-receptor type 130.446
Klf7Kruppel-like factor 7 (ubiquitous)0.443
Stag2stromal antigen 20.442
Lama5laminin, alpha 50.431
Hmha1histocompatibility (minor) HA-10.430
Ephb2Eph receptor B20.426
Itga3integrin alpha 30.425
Ifi47interferon gamma inducible protein 470.424
Epb4.1l2erythrocyte protein band 4.1-like 20.420
Leprleptin receptor0.420
Kcnk2potassium channel, subfamily K, member 20.419
Tgtp2T-cell specific GTPase 20.419
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.407
Nrbp2nuclear receptor binding protein 20.405
Pnp2purine-nucleoside phosphorylase 20.402
Adrb1adrenergic receptor, beta 10.401
Bcrbreakpoint cluster region0.388
Irf1interferon regulatory factor 10.387
Ctnnb1catenin (cadherin associated protein), beta 10.386
Klklotho0.382
Dlg4discs, large homolog 4 (Drosophila)0.380
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.374
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.374
Pnpla2patatin-like phospholipase domain containing 20.373
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.369
Efnb1ephrin B10.368
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.363
Rapgef1Rap guanine nucleotide exchange factor (GEF) 10.362
Nf2neurofibromatosis 20.361
Sash3SAM and SH3 domain containing 30.361
Rap1aRAS-related protein-1a0.360
Lystlysosomal trafficking regulator0.360
Retret proto-oncogene0.359
Arhgap1Rho GTPase activating protein 10.357
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.354
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sem-5Protein SEM-50.657
lag-1Protein LAG-10.530
gpr-1Protein GPR-10.447
rgl-1Protein RGL-10.421
goa-1Protein GOA-10.420
etr-1Protein ETR-10.370
snf-1Protein SNF-10.334
mig-2Protein MIG-20.329
eor-2Protein EOR-20.291
itr-1Protein ITR-10.244
csnk-1Protein CSNK-10.236
sma-6Protein SMA-60.225
kin-2Protein KIN-20.212
cmd-1Protein CMD-10.204
madf-5Protein MADF-50.201
CELE_F47G4.4Protein F47G4.40.201
mtm-3Protein MTM-30.182
gpb-1Protein GPB-10.180
dpm-1Protein DPM-10.177
ced-10Protein CED-100.176
CELE_T10D4.6Protein T10D4.60.172
gly-7Protein GLY-70.169
dpf-3Protein DPF-30.162
ykt-6Protein YKT-60.161
gei-18Protein GEI-180.151
T23F11.1Protein T23F11.10.141
cyld-1Protein CYLD-10.140
sli-1Protein SLI-10.139
C11E4.6Protein C11E4.60.135
unc-62Protein UNC-620.129
unc-26Protein UNC-260.127
gar-3Protein GAR-30.116
lec-1Protein LEC-10.114
fhod-1Protein FHOD-10.114
unc-60Protein UNC-600.106
T04F8.6Protein T04F8.60.103
let-60Protein LET-600.099
F52G3.1Protein F52G3.10.098
tag-123Protein TAG-1230.098
tat-1Protein TAT-10.096
zoo-1Protein ZOO-10.094
stau-1Protein STAU-10.092
Y110A7A.4Protein Y110A7A.40.092
dpy-21Protein DPY-210.092
tpxl-1Protein TPXL-10.091
ddr-2Protein DDR-20.088
CELE_F53C11.5Protein F53C11.50.086
sup-17Protein SUP-170.085
rab-11.1Protein RAB-11.10.085
spd-2Protein SPD-20.085
rps-2Protein RPS-20.084
zfp-3Protein ZFP-30.084
pdl-1Protein PDL-10.084
CELE_W07A8.2Protein W07A8.20.082
ina-1Protein INA-10.082
unc-119Protein UNC-1190.080
smp-1Protein SMP-10.080
CELE_Y53F4B.5Protein Y53F4B.50.080
daf-19Protein DAF-190.078
klp-7Protein KLP-70.077
tag-335Protein TAG-3350.076
rars-2Protein RARS-20.075
unc-53Protein UNC-530.075
C18E9.2Protein C18E9.20.075
abts-1Protein ABTS-10.074
F35G2.1Protein F35G2.10.074
zfp-1Protein ZFP-10.073
pfn-2Protein PFN-20.073
mpk-1Protein MPK-10.072
C06G3.9Protein C06G3.90.071
vps-32.1Protein VPS-32.10.071
rpl-5Protein RPL-50.071
sam-10Protein SAM-100.070
egrh-1Protein EGRH-10.070
sto-4Protein STO-40.069
C27H2.2Protein C27H2.20.069
F54D12.4Protein F54D12.40.069
R10E12.2Protein R10E12.20.069
osm-5Protein OSM-50.067
rab-39Protein RAB-390.067
CELE_Y60A3A.9Protein Y60A3A.90.066
dgk-4Protein DGK-40.066
ulp-2Protein ULP-20.065
rab-5Protein RAB-50.064
dnj-16Protein DNJ-160.063
CELE_K08E7.6Protein K08E7.60.063
cgef-2Protein CGEF-20.063
gcs-1Protein GCS-10.062
svh-2Protein SVH-20.060
mrck-1Protein MRCK-10.059
CELE_F25B4.8Protein F25B4.80.058
apg-1Protein APG-10.058
cdk-1Protein CDK-10.058
unc-79Protein UNC-790.057
unc-71Protein UNC-710.057
stim-1Protein STIM-10.057
jbts-14Protein JBTS-140.056
unc-31Protein UNC-310.056
pat-3Protein PAT-30.056
upp-1Protein UPP-10.056
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pak2ap21 (CDKN1A)-activated kinase 2a0.602
bidaBH3 interacting domain death agonist0.577
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.375
arf5ADP-ribosylation factor 50.366
gsnagelsolin a0.358
copebcore promoter element binding protein0.319
plxnb2aplexin b2a0.316
nf1aneurofibromin 1a0.301
gna12guanine nucleotide binding protein (G protein) alpha 120.280
c10orf11c10orf11 homolog (H. sapiens)0.273
mcl1bmyeloid cell leukemia sequence 1b0.272
pvrl1bpoliovirus receptor-related 1b0.269
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.260
rab1aRAB1A, member RAS oncogene family0.249
zgc:56085zgc:560850.248
gnao1aguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a0.244
sept2septin 20.232
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.229
adrb2aadrenergic receptor, beta 2a0.228
zbtb4zinc finger and BTB domain containing 40.224
trpv4transient receptor potential cation channel, subfamily V, member 40.223
heatr3HEAT repeat containing 30.218
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.218
si:ch211-232m7.1si:ch211-232m7.10.216
cnn2calponin 20.216
iqgap1IQ motif containing GTPase activating protein 10.213
esyt3extended synaptotagmin-like protein 30.210
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.210
ppp3cbprotein phosphatase 3, catalytic subunit, beta isozyme0.210
tm9sf2transmembrane 9 superfamily member 20.204
bcl2B-cell leukemia/lymphoma 20.203
alcambactivated leukocyte cell adhesion molecule b0.198
pvrl1apoliovirus receptor-related 1a0.198
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.193
bactin2bactin20.178
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.176
LOC567131calcitonin gene-related peptide type 1 receptor-like0.172
atp1b3aATPase, Na+/K+ transporting, beta 3a polypeptide0.169
srprsignal recognition particle receptor (docking protein)0.168
rhoaaras homolog gene family, member Aa0.168
mecp2methyl CpG binding protein 20.166
arpc5aactin related protein 2/3 complex, subunit 5A0.166
s100a10aS100 calcium binding protein A10a0.164
pacsin3protein kinase C and casein kinase substrate in neurons 30.162
zgc:77517zgc:775170.161
s100bS100 calcium binding protein, beta (neural)0.159
stc1lstanniocalcin 1, like0.158
pobpartial optokinetic response b0.157
sbf1SET binding factor 10.155
arf2ADP-ribosylation factor 20.155
ccdc47coiled-coil domain containing 470.153
ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.149
dlg1discs, large (Drosophila) homolog 10.148
tmf1TATA element modulatory factor 10.145
tpm4tropomyosin 40.143
rtcd1RNA terminal phosphate cyclase domain 10.141
pfn1profilin 10.139
ppargperoxisome proliferator activated receptor gamma0.138
zeb1zinc finger E-box binding homeobox 10.137
tm9sf4transmembrane 9 superfamily protein member 40.136
zgc:63637zgc:636370.135
srmspermidine synthase0.132
sox11bSRY-box containing gene 11b0.129
dusp4dual specificity phosphatase 40.129
snx6sorting nexin 60.129
krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.129
grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.128
arpc5bactin related protein 2/3 complex, subunit 5B0.127
rap1bRAS related protein 1b0.126
trpa1btransient receptor potential cation channel, subfamily A, member 1b0.126
mcl1amyeloid cell leukemia sequence 1a0.125
nf1bneurofibromin 1b0.125
vps26blvacuolar protein sorting 26 homolog B, like0.124
zgc:153129zgc:1531290.123
sypl2bsynaptophysin-like 2b0.120
rock2arho-associated, coiled-coil containing protein kinase 2a0.120
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.118
gngt2bguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b0.116
ef1aelongation factor 1-alpha0.115
yrkYes-related kinase0.114
baxabcl2-associated X protein, a0.113
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.113
gro2groucho 20.113
ptrfbpolymerase I and transcript release factor b0.113
rab7RAB7, member RAS oncogene family0.111
zgc:63831zgc:638310.110
dopey1dopey family member 10.108
lrrn1leucine rich repeat neuronal 10.107
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.107
zgc:172028zgc:1720280.107
nfkbiznuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.105
atf3activating transcription factor 30.105
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.105
si:dkey-91i17.1si:dkey-91i17.10.103
zgc:56272zgc:562720.103
icnictacalcin0.102
ap3m2adaptor-related protein complex 3, mu 2 subunit0.102
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.102
cdkl1cyclin-dependent kinase-like 1 (CDC2-related kinase)0.102
pmaip1phorbol-12-myristate-13-acetate-induced protein 10.101
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.990
Pi3K92ECG4141 gene product from transcript CG4141-RB0.980
rlrolled0.858
drkdownstream of receptor kinase0.767
Ras85DRas oncogene at 85D0.756
benbendless0.744
Rho1CG8416 gene product from transcript CG8416-RB0.727
RhebCG1081 gene product from transcript CG1081-RA0.703
flwflapwing0.683
cnocanoe0.672
CG8155CG8155 gene product from transcript CG8155-RA0.664
mbcmyoblast city0.657
ttktramtrack0.622
PtenCG5671 gene product from transcript CG5671-RB0.585
Vps35Vacuolar protein sorting 350.544
Rab7Rab-protein 70.526
Stat92ESignal-transducer and activator of transcription protein at 92E0.507
Su(H)Suppressor of Hairless0.474
carcarnation0.454
mbtmushroom bodies tiny0.427
Syx7Syntaxin 70.415
rokRho-kinase0.387
AbiAbelson interacting protein0.378
Pk61CProtein kinase 61C0.368
SosSon of sevenless0.367
stumpsCG31317 gene product from transcript CG31317-RC0.365
dosdaughter of sevenless0.355
chicchickadee0.354
lgslegless0.354
bazbazooka0.318
dysdysfusion0.311
drprdraper0.306
Rab11Rab-protein 110.304
rapsrapsynoid0.296
synjsynaptojanin0.286
PknProtein kinase related to protein kinase N0.271
Gienovel GTPase indispensable for equal segregation of chromosomes0.271
TSG101tumor suppressor protein 1010.270
MtlMig-2-like0.260
S6kRPS6-p70-protein kinase0.256
pod1CG4532 gene product from transcript CG4532-RF0.253
Gyc-89DaGuanylyl cyclase at 89Da0.246
auxauxillin0.246
aveaveugle0.240
MoeMoesin0.234
MadMothers against dpp0.234
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.221
edlETS-domain lacking0.221
smosmoothened0.216
Gap69CGTPase-activating protein 69C0.216
ShcSHC-adaptor protein0.213
NaCP60ENa channel protein 60E0.211
PliPellino0.210
gekgenghis khan0.206
TlToll0.204
Ras64BRas oncogene at 64B0.203
Arf79FADP ribosylation factor 79F0.203
stgstring0.203
jebjelly belly0.200
RalaRas-related protein0.190
Rab6Rab-protein 60.180
klgklingon0.172
Pak3CG14895 gene product from transcript CG14895-RA0.170
didumdilute class unconventional myosin0.170
CG32772CG32772 gene product from transcript CG32772-RC0.163
Rbsn-5Rabenosyn-50.160
LnkCG17367 gene product from transcript CG17367-RC0.160
trptransient receptor potential0.159
ctaconcertina0.156
giggigas0.155
Vps16AVacuolar protein sorting 16A0.154
MTF-1Metal response element-binding Transcription Factor-10.153
dmdiminutive0.153
EphrinCG1862 gene product from transcript CG1862-RA0.151
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.148
Gyc-89DbGuanylyl cyclase at 89Db0.146
CG17082CG17082 gene product from transcript CG17082-RD0.146
WnkCG7177 gene product from transcript CG7177-RA0.142
armarmadillo0.137
l(2)k16918lethal (2) k169180.134
ninaEneither inactivation nor afterpotential E0.133
Galpha49BG protein alpha49B0.132
Rab2Rab-protein 20.132
futschCG34387 gene product from transcript CG34387-RC0.132
cpbcapping protein beta0.131
trioCG18214 gene product from transcript CG18214-RA0.127
PakPAK-kinase0.124
rheaCG6831 gene product from transcript CG6831-RA0.124
LanALaminin A0.123
kenken and barbie0.123
eglegalitarian0.123
SNF1ASNF1A/AMP-activated protein kinase0.120
p130CASCG1212 gene product from transcript CG1212-RA0.120
galectinCG11372 gene product from transcript CG11372-RA0.120
bbgbig bang0.120
G-ialpha65AG protein alphai subunit 65A0.118
Eip63EEcdysone-induced protein 63E0.118
CG12004CG12004 gene product from transcript CG12004-RC0.116
sevsevenless0.113
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.112
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
DNM2dynamin 20.999
SFNstratifin0.998
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.998
PTK2PTK2 protein tyrosine kinase 20.997
WDYHV1WDYHV motif containing 10.994
RAB5ARAB5A, member RAS oncogene family0.990
DNM1dynamin 10.989
OCRLoculocerebrorenal syndrome of Lowe0.988
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.988
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.986
SH3KBP1SH3-domain kinase binding protein 10.985
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.984
ITSN1intersectin 1 (SH3 domain protein)0.981
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.974
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.973
EGFRepidermal growth factor receptor0.971
NCK2NCK adaptor protein 20.968
GRB7growth factor receptor-bound protein 70.954
DOCK1dedicator of cytokinesis 10.947
S100A6S100 calcium binding protein A60.931
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.931
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.929
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.922
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.919
MARK3MAP/microtubule affinity-regulating kinase 30.916
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.904
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.894
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.894
ARRB1arrestin, beta 10.892
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.887
RHOAras homolog gene family, member A0.883
RIN3Ras and Rab interactor 30.880
EEA1early endosome antigen 10.877
BCL2L1BCL2-like 10.872
ADAM15ADAM metallopeptidase domain 150.858
ADRBK1adrenergic, beta, receptor kinase 10.853
SH3BP2SH3-domain binding protein 20.849
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)0.848
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.847
MDM2Mdm2 p53 binding protein homolog (mouse)0.844
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.832
S100A8S100 calcium binding protein A80.831
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.828
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.823
EEF1Geukaryotic translation elongation factor 1 gamma0.821
S100A11S100 calcium binding protein A110.820
ABI1abl-interactor 10.819
RAB1ARAB1A, member RAS oncogene family0.817
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.813
SH3RF1SH3 domain containing ring finger 10.804
PTK2BPTK2B protein tyrosine kinase 2 beta0.791
SEC24ASEC24 family, member A (S. cerevisiae)0.786
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.779
TSC2tuberous sclerosis 20.779
JUNjun proto-oncogene0.776
RHEBRas homolog enriched in brain0.746
STAT5Asignal transducer and activator of transcription 5A0.731
NCK1NCK adaptor protein 10.728
SOS1son of sevenless homolog 1 (Drosophila)0.718
ARL2ADP-ribosylation factor-like 20.701
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.701
RGS2regulator of G-protein signaling 2, 24kDa0.697
BCAR1breast cancer anti-estrogen resistance 10.696
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.695
TNK2tyrosine kinase, non-receptor, 20.683
NCKAP1NCK-associated protein 10.679
NCF2neutrophil cytosolic factor 20.679
GRB2growth factor receptor-bound protein 20.674
S100BS100 calcium binding protein B0.656
S100A9S100 calcium binding protein A90.651
RRAGARas-related GTP binding A0.642
CCR5chemokine (C-C motif) receptor 50.634
GIMAP7GTPase, IMAP family member 70.625
RABEP1rabaptin, RAB GTPase binding effector protein 10.622
CALM1calmodulin 1 (phosphorylase kinase, delta)0.619
ANKRD28ankyrin repeat domain 280.619
RABAC1Rab acceptor 1 (prenylated)0.609
SEPT2septin 20.600
ZMYND11zinc finger, MYND-type containing 110.596
RAB14RAB14, member RAS oncogene family0.595
SYNJ1synaptojanin 10.594
GOLGA2golgin A20.592
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.587
GDI2GDP dissociation inhibitor 20.583
TRAF3TNF receptor-associated factor 30.581
RANBP9RAN binding protein 90.581
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.574
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.572
RAP1BRAP1B, member of RAS oncogene family0.570
FNBP1formin binding protein 10.569
PAK4p21 protein (Cdc42/Rac)-activated kinase 40.560
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.553
SQSTM1sequestosome 10.544
PKN3protein kinase N30.540
MAP3K5mitogen-activated protein kinase kinase kinase 50.538
TSC1tuberous sclerosis 10.536
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Arl1ADP-ribosylation factor-like 10.417
Pja2praja 2, RING-H2 motif containing0.218
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.199
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.163
Pfn1profilin 10.163
Ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.158
Amphamphiphysin0.140
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.128
Epas1endothelial PAS domain protein 10.121
Arf4ADP-ribosylation factor 40.109
Gucy1b3guanylate cyclase 1, soluble, beta 30.109
Dlg1discs, large homolog 1 (Drosophila)0.104
Hrhairless0.103
Jarid1ajumonji, AT rich interactive domain 1A (Rbp2 like)0.094
RT1-DMaRT1 class II, locus DMa0.093
Jtbjumping translocation breakpoint0.089
Scn3bsodium channel, voltage-gated, type III, beta0.089
Dlg3discs, large homolog 3 (Drosophila)0.087
Tgfbr2transforming growth factor, beta receptor II0.084
Sdc3syndecan 30.083
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.078
Nckap1NCK-associated protein 10.078
Arpc2actin related protein 2/3 complex, subunit 20.077
SvopSV2 related protein0.077
Dapk3death-associated protein kinase 30.075
Hk1hexokinase 10.073
Sstr1somatostatin receptor 10.071
Mapre1microtubule-associated protein, RP/EB family, member 10.070
Stxbp5syntaxin binding protein 5 (tomosyn)0.068
Fgfr1Fibroblast growth factor receptor 10.068
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.067
Utrnutrophin0.067
Exoc5exocyst complex component 50.066
Dnm1dynamin 10.066
Rab1RAB1, member RAS oncogene family0.065
Rab18RAB18, member RAS oncogene family0.063
Snap23synaptosomal-associated protein 230.063
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.062
Zfp37zinc finger protein 370.061
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.060
Sh3gl2SH3-domain GRB2-like 20.058
Ralav-ral simian leukemia viral oncogene homolog A (ras related)0.058
Shank2SH3 and multiple ankyrin repeat domains 20.057
Eif5eukaryotic translation initiation factor 50.056
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.056
Dock9dedicator of cytokinesis 90.056
Pum1pumilio homolog 1 (Drosophila)0.056
Mtpnmyotrophin0.055
Dnm2dynamin 20.055
Brafv-raf murine sarcoma viral oncogene homolog B10.055
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.054
Gipc1GIPC PDZ domain containing family, member 10.054
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.053
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.053
Wdr7WD repeat domain 70.052
Cfpcomplement factor properdin0.051
Sept10septin 100.051
Sec11aSEC11 homolog A (S. cerevisiae)0.050
Prkchprotein kinase C, eta0.050
Pdp1pyruvate dehyrogenase phosphatase catalytic subunit 10.050
Rab5aRAB5A, member RAS oncogene family0.049
Dctn1dynactin 10.049
Cyth3cytohesin 30.049
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.048
Sox17SRY (sex determining region Y)-box 170.048
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.048
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.048
Cnp2',3'-cyclic nucleotide 3' phosphodiesterase0.047
TekTEK tyrosine kinase, endothelial0.047
Clpscolipase, pancreatic0.047
Psma3proteasome (prosome, macropain) subunit, alpha type 30.047
Ephb1Eph receptor B10.046
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.045
Pls3plastin 3 (T-isoform)0.045
Homer1homer homolog 1 (Drosophila)0.045
Sbf1SET binding factor 10.045
Usf2upstream transcription factor 2, c-fos interacting0.044
Bin1bridging integrator 10.044
Gria2glutamate receptor, ionotropic, AMPA 20.044
Eif4e2eukaryotic translation initiation factor 4E family member 20.044
Myo1cmyosin IC0.044
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.044
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.044
Cd8bCD8b molecule0.044
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.043
Mcpt4mast cell protease 40.043
Nr4a2nuclear receptor subfamily 4, group A, member 20.043
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.042
Camk4calcium/calmodulin-dependent protein kinase IV0.042
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.042
Itpkainositol 1,4,5-trisphosphate 3-kinase A0.042
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.041
Rab7aRAB7A, member RAS oncogene family0.041
Smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.041
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.041
Pdcd10programmed cell death 100.041
Akap12A kinase (PRKA) anchor protein 120.041
Epb41l1erythrocyte membrane protein band 4.1-like 10.041
Mertkc-mer proto-oncogene tyrosine kinase0.041
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.041
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RHO1Rho1p0.892
GDI1Gdi1p0.874
YIP3Yip3p0.688
YPT52Ypt52p0.661
STE5Ste5p0.644
SEC13Sec13p0.602
MKK1Mkk1p0.549
SUI3Sui3p0.532
AVO1Avo1p0.478
YPT6Ypt6p0.414
STE4Ste4p0.385
VPS15Vps15p0.344
SEC2Sec2p0.324
YPT31Ypt31p0.309
ACK1Ack1p0.283
YPT1Ypt1p0.277
GIC2Gic2p0.269
SEC16Sec16p0.266
ROM2Rom2p0.241
YPT10Ypt10p0.240
SEC24Sec24p0.240
YPT53Ypt53p0.224
SEC4Sec4p0.209
TOM1Tom1p0.207
PKC1Pkc1p0.174
BEM3Bem3p0.170
FAR1Far1p0.163
KOG1Kog1p0.155
SED5Sed5p0.151
IRA1Ira1p0.151
PEP5Pep5p0.145
TRS65Trs65p0.143
BUD6Bud6p0.138
STT4Stt4p0.134
TRS31Trs31p0.132
YLR257Whypothetical protein0.125
YHR127Whypothetical protein0.119
BET3Bet3p0.115
CDC24Cdc24p0.105
VPS17Vps17p0.103
TOR1Tor1p0.102
STE2Ste2p0.100
FYV8Fyv8p0.099
TSC11Tsc11p0.098
PEA2Pea2p0.098
VTI1Vti1p0.097
TRX1Trx1p0.094
CCT4Cct4p0.093
NOP7Nop7p0.092
KES1Kes1p0.090
IOC3Ioc3p0.090
VPS41Vps41p0.087
NIP7Nip7p0.087
BUL1Bul1p0.080
SSK2Ssk2p0.078
ELP4Elp4p0.078
ATG20Atg20p0.077
MON1Mon1p0.076
HSV2Hsv2p0.073
APM3Apm3p0.073
AFG3Afg3p0.072
RFC1Rfc1p0.072
KAP114Kap114p0.072
PIS1Pis1p0.071
ATG14Atg14p0.071
CDC42Cdc42p0.071
HLJ1Hlj1p0.069
KEL1Kel1p0.069
NOG2Nog2p0.068
YMR258Chypothetical protein0.068
STE20Ste20p0.068
YRB1Yrb1p0.067
YIP1Yip1p0.067
SMM1Smm1p0.067
RGD1Rgd1p0.066
SKM1Skm1p0.065
NSA2Nsa2p0.065
EXO84Exo84p0.063
RPM2Rpm2p0.062
SPA2Spa2p0.061
RER2Rer2p0.061
YIL055Chypothetical protein0.060
HYP2Hyp2p0.060
MDS3Mds3p0.060
PRS2Prs2p0.059
VPS21Vps21p0.058
CLN3Cln3p0.057
YJR084Whypothetical protein0.057
YPT7Ypt7p0.056
CHS1Chs1p0.056
APL4Apl4p0.055
YGL036Whypothetical protein0.055
RPN14Rpn14p0.054
YML002Whypothetical protein0.054
RRP9Rrp9p0.053
RRS1Rrs1p0.053
URA6Ura6p0.053
AKL1Akl1p0.053
NYV1Nyv1p0.052
YNL108Chypothetical protein0.051