The network for 'gpi anchor metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gpi anchor metabolic process

The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.

NameDescriptionProbabilityFunc Analog Organism
Immp1lIMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)0.538
5730494N06RikRIKEN cDNA 5730494N06 gene0.488
1110058L19RikRIKEN cDNA 1110058L19 gene0.126
Atp5sATP synthase, H+ transporting, mitochondrial F0 complex, subunit s0.118
Pvalbparvalbumin0.100
Srp14signal recognition particle 140.094
1810030N24RikRIKEN cDNA 1810030N24 gene0.081
Acyp1acylphosphatase 1, erythrocyte (common) type0.070
Cstf2cleavage stimulation factor, 3' pre-RNA subunit 20.064
Eef1a2eukaryotic translation elongation factor 1 alpha 20.060
Fam103a1family with sequence similarity 103, member A10.055
Tmem218transmembrane protein 2180.054
1500031L02RikRIKEN cDNA 1500031L02 gene0.052
Rnf7ring finger protein 70.050
Fntafarnesyltransferase, CAAX box, alpha0.045
Pex7peroxisomal biogenesis factor 70.044
Pigophosphatidylinositol glycan anchor biosynthesis, class O0.043
Anlnanillin, actin binding protein0.039
Tmem128transmembrane protein 1280.037
Isca1iron-sulfur cluster assembly 1 homolog (S. cerevisiae)0.037
Paip2polyadenylate-binding protein-interacting protein 20.036
0610007C21RikRIKEN cDNA 0610007C21 gene0.034
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.034
2310044H10RikRIKEN cDNA 2310044H10 gene0.033
Ints1integrator complex subunit 10.033
Pigfphosphatidylinositol glycan anchor biosynthesis, class F0.033
Polr3kpolymerase (RNA) III (DNA directed) polypeptide K0.033
Lyrm2LYR motif containing 20.032
H47histocompatibility 470.032
Tuba8tubulin, alpha 80.031
Wdr20aWD repeat domain 20A0.031
Atad3aATPase family, AAA domain containing 3A0.029
Pygmmuscle glycogen phosphorylase0.028
Arl3ADP-ribosylation factor-like 30.028
Zmiz2zinc finger, MIZ-type containing 20.028
Polr2kpolymerase (RNA) II (DNA directed) polypeptide K0.027
Tprgltransformation related protein 63 regulated like0.027
2410022L05RikRIKEN cDNA 2410022L05 gene0.027
Tcaptitin-cap0.025
Hps4Hermansky-Pudlak syndrome 4 homolog (human)0.023
1110005A03RikRIKEN cDNA 1110005A03 gene0.023
Camlcalcium modulating ligand0.022
0610037P05RikRIKEN cDNA 0610037P05 gene0.022
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.022
Rnf123ring finger protein 1230.021
Brp44brain protein 440.021
Med31mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)0.021
Pdcd2programmed cell death 20.021
Actr6ARP6 actin-related protein 6 homolog (yeast)0.020
March6membrane-associated ring finger (C3HC4) 60.020
Bnip3BCL2/adenovirus E1B interacting protein 30.020
2700097O09RikRIKEN cDNA 2700097O09 gene0.020
Srp19signal recognition particle 190.019
Ube2tubiquitin-conjugating enzyme E2T (putative)0.019
Fitm1fat storage-inducing transmembrane protein 10.019
Tomm7translocase of outer mitochondrial membrane 7 homolog (yeast)0.018
1110059E24RikRIKEN cDNA 1110059E24 gene0.018
Gstm5glutathione S-transferase, mu 50.018
Pfn2profilin 20.017
Haus3HAUS augmin-like complex, subunit 30.017
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.017
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.016
Creld2cysteine-rich with EGF-like domains 20.016
Sdf2stromal cell derived factor 20.016
Uchl5ubiquitin carboxyl-terminal esterase L50.016
TctaT-cell leukemia translocation altered gene0.016
Hsbp1heat shock factor binding protein 10.016
Hiat1hippocampus abundant gene transcript 10.016
Vti1bvesicle transport through interaction with t-SNAREs 1B homolog0.015
Man2c1mannosidase, alpha, class 2C, member 10.015
Yipf5Yip1 domain family, member 50.015
1700025K23RikRIKEN cDNA 1700025K23 gene0.015
Mutedmuted0.015
1700029F09RikRIKEN cDNA 1700029F09 gene0.015
BC023829cDNA sequence BC0238290.015
Rbm15RNA binding motif protein 150.015
Tm2d2TM2 domain containing 20.014
2700060E02RikRIKEN cDNA 2700060E02 gene0.014
Gemin6gem (nuclear organelle) associated protein 60.014
Unc50unc-50 homolog (C. elegans)0.014
Snip1Smad nuclear interacting protein 10.014
Criptcysteine-rich PDZ-binding protein0.014
Spcs1signal peptidase complex subunit 1 homolog (S. cerevisiae)0.014
Slc30a5solute carrier family 30 (zinc transporter), member 50.014
1110067D22RikRIKEN cDNA 1110067D22 gene0.014
Ndfip1Nedd4 family interacting protein 10.013
Slc25a14solute carrier family 25 (mitochondrial carrier, brain), member 140.013
Tab3TGF-beta activated kinase 1/MAP3K7 binding protein 30.013
Asb11ankyrin repeat and SOCS box-containing 110.013
Tbc1d19TBC1 domain family, member 190.013
Krt10keratin 100.013
Nup35nucleoporin 350.013
2610002J02RikRIKEN cDNA 2610002J02 gene0.013
Ptgdsprostaglandin D2 synthase (brain)0.013
Rg9mtd3RNA (guanine-9-) methyltransferase domain containing 30.013
Cpoxcoproporphyrinogen oxidase0.013
Pam16presequence translocase-asssociated motor 16 homolog (S. cerevisiae)0.013
Snx14sorting nexin 140.012
Tsg101tumor susceptibility gene 1010.012
Ap4s1adaptor-related protein complex AP-4, sigma 10.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nkd1naked cuticle homolog 1 (Drosophila)0.092
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GPAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)0.761
PIGTphosphatidylinositol glycan anchor biosynthesis, class T0.461
SEP1515 kDa selenoprotein0.115
TSTA3tissue specific transplantation antigen P35B0.098
PIGSphosphatidylinositol glycan anchor biosynthesis, class S0.048
CUTAcutA divalent cation tolerance homolog (E. coli)0.040
G6PC3glucose 6 phosphatase, catalytic, 30.033
PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 10.031
SCAND1SCAN domain containing 10.031
SLMO2slowmo homolog 2 (Drosophila)0.027
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.019
MMADHCmethylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria0.017
GSSglutathione synthetase0.015
RAB1BRAB1B, member RAS oncogene family0.015
BCAS2breast carcinoma amplified sequence 20.015
GANABglucosidase, alpha; neutral AB0.014
POLR2Kpolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa0.014
CCDC59coiled-coil domain containing 590.014
C1DC1D nuclear receptor corepressor0.012
SNRPB2small nuclear ribonucleoprotein polypeptide B0.012
CRY1cryptochrome 1 (photolyase-like)0.011
PMVKphosphomevalonate kinase0.011
PFDN4prefoldin subunit 40.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
LAS21Las21p0.989
GAB1Gab1p0.966
GPI17Gpi17p0.920
GAA1Gaa1p0.862
GWT1Gwt1p0.763
PER1Per1p0.548
GPI2Gpi2p0.482
ALG6Alg6p0.241
GUP1Gup1p0.232
GPI11Gpi11p0.229
ARV1Arv1p0.223
ERD2Erd2p0.221
GPI16Gpi16p0.198
GPI13Gpi13p0.183
GPI1Gpi1p0.181
CHS7Chs7p0.178
SEC59Sec59p0.170
YJR015Whypothetical protein0.169
SPF1Spf1p0.136
ALG11Alg11p0.116
OST2Ost2p0.108
RFT1Rft1p0.088
CNE1Cne1p0.086
YGL140Chypothetical protein0.083
MCD4Mcd4p0.081
MST27Mst27p0.081
BIG1Big1p0.073
PFA4Pfa4p0.071
PMT3Pmt3p0.061
OSH7Osh7p0.060
KRE2Kre2p0.059
YJR012Chypothetical protein0.059
ROT2Rot2p0.056
SVP26Svp26p0.056
YLR036Chypothetical protein0.055
GPI19Gpi19p0.053
BST1Bst1p0.053
SPT14Spt14p0.052
LHS1Lhs1p0.048
SFT1Sft1p0.048
AXL2Axl2p0.047
YER186Chypothetical protein0.047
SRD1Srd1p0.045
YHR078Whypothetical protein0.043
EMP24Emp24p0.042
BET3Bet3p0.042
AVT5Avt5p0.041
YAR028Whypothetical protein0.040
ELO1Elo1p0.040
ERV15Erv15p0.039
SMP3Smp3p0.039
YAR068Whypothetical protein0.039
LEU2Leu2p0.039
YLR162Whypothetical protein0.038
AGE1Age1p0.037
YSC83Ysc83p0.037
QNS1Qns1p0.037
SPL2Spl2p0.037
VCX1Vcx1p0.036
YLR264C-Ahypothetical protein0.036
YOL038C-Ahypothetical protein0.035
YOR385Whypothetical protein0.034
PPQ1Ppq1p0.034
LDB16Ldb16p0.034
ARP10Arp10p0.033
YNL040Whypothetical protein0.033
YAR066Whypothetical protein0.032
MER1Mer1p0.032
DIE2Die2p0.032
CWH43Cwh43p0.032
PHS1Phs1p0.032
YPR071Whypothetical protein0.031
ALG1Alg1p0.031
RCE1Rce1p0.031
ARG8Arg8p0.031
UPS3Ups3p0.031
TSC3Tsc3p0.031
RDS3Rds3p0.030
OPT2Opt2p0.030
CPD1Cpd1p0.030
DFG10Dfg10p0.030
CTR2Ctr2p0.029
VBA5Vba5p0.029
RRI1Rri1p0.029
FMT1Fmt1p0.029
FAU1Fau1p0.029
ZPS1Zps1p0.028
ATP6Atp6p0.028
NEO1Neo1p0.028
TAD2Tad2p0.028
YCH1Ych1p0.028
AUA1Aua1p0.027
ERI1Eri1p0.027
PFA5Pfa5p0.027
YPR157Whypothetical protein0.027
MID1Mid1p0.027
YLR042Chypothetical protein0.027
SNF11Snf11p0.027
YPR153Whypothetical protein0.027
HAC1Hac1p0.027