The network for 'phagolysosome assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

phagolysosome assembly

The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.

NameDescriptionProbabilityFunc Analog Organism
Ush1gUsher syndrome 1G homolog (human)0.769
Ush1cUsher syndrome 1C homolog (human)0.756
Cdh23cadherin 23 (otocadherin)0.353
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.330
Pcdh15protocadherin 150.176
Tbx10T-box 100.099
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.065
S1pr2sphingosine-1-phosphate receptor 20.064
Pou4f3POU domain, class 4, transcription factor 30.056
Myo15myosin XV0.055
Grxcr1glutaredoxin, cysteine rich 10.050
Rab3il1RAB3A interacting protein (rabin3)-like 10.048
Ctszcathepsin Z0.046
Asah1N-acylsphingosine amidohydrolase 10.045
Gpr98G protein-coupled receptor 980.045
Mfsd1major facilitator superfamily domain containing 10.038
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.034
Sat1spermidine/spermine N1-acetyl transferase 10.032
Dscr3Down syndrome critical region gene 30.029
Tbxas1thromboxane A synthase 1, platelet0.029
Hmha1histocompatibility (minor) HA-10.028
Myo6myosin VI0.027
5033414D02RikRIKEN cDNA 5033414D02 gene0.027
Col16a1collagen, type XVI, alpha 10.026
Renbprenin binding protein0.026
Anxa4annexin A40.026
RragcRas-related GTP binding C0.025
Slc26a5solute carrier family 26, member 50.025
Vps35vacuolar protein sorting 350.025
Dpp7dipeptidylpeptidase 70.024
S1pr3sphingosine-1-phosphate receptor 30.024
Snx6sorting nexin 60.024
Spg21spastic paraplegia 21 homolog (human)0.023
Hexbhexosaminidase B0.023
Gfi1growth factor independent 10.022
Mfap5microfibrillar associated protein 50.022
Stx7syntaxin 70.021
Snap23synaptosomal-associated protein 230.021
Lyl1lymphoblastomic leukemia 10.020
Fundc1FUN14 domain containing 10.020
Galk2galactokinase 20.019
Ptgirprostaglandin I receptor (IP)0.019
Ankrd2ankyrin repeat domain 2 (stretch responsive muscle)0.018
Spsb2splA/ryanodine receptor domain and SOCS box containing 20.018
Gata1GATA binding protein 10.018
Ptprqprotein tyrosine phosphatase, receptor type, Q0.018
Alg10basparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)0.018
Npc2Niemann Pick type C20.018
Hexahexosaminidase A0.018
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.017
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.017
Arhgap9Rho GTPase activating protein 90.017
Col14a1collagen, type XIV, alpha 10.017
Bocbiregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein0.016
Leprotleptin receptor overlapping transcript0.016
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.016
Adcy4adenylate cyclase 40.016
0610031J06RikRIKEN cDNA 0610031J06 gene0.016
Cnot6lCCR4-NOT transcription complex, subunit 6-like0.016
Mmp23matrix metallopeptidase 230.015
Il10rbinterleukin 10 receptor, beta0.015
Tspan32tetraspanin 320.015
Capn6calpain 60.015
Aldh3b1aldehyde dehydrogenase 3 family, member B10.015
Slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.015
Ltc4sleukotriene C4 synthase0.015
Laptm5lysosomal-associated protein transmembrane 50.015
Mfap4microfibrillar-associated protein 40.015
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.014
Cmtm3CKLF-like MARVEL transmembrane domain containing 30.014
Gpr50G-protein-coupled receptor 500.014
Sdcbpsyndecan binding protein0.014
Snx14sorting nexin 140.014
Scpep1serine carboxypeptidase 10.013
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.013
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.013
Rap1bRAS related protein 1b0.013
Vps26avacuolar protein sorting 26 homolog A (yeast)0.013
Psmd10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.013
Cdrt4CMT1A duplicated region transcript 40.013
Fermt3fermitin family homolog 3 (Drosophila)0.013
Gpsm3G-protein signalling modulator 3 (AGS3-like, C. elegans)0.013
Naglualpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)0.013
Clec11aC-type lectin domain family 11, member a0.013
Cybacytochrome b-245, alpha polypeptide0.012
Trpv2transient receptor potential cation channel, subfamily V, member 20.012
Mab21l2mab-21-like 2 (C. elegans)0.012
Lgals8lectin, galactose binding, soluble 80.012
Il27rainterleukin 27 receptor, alpha0.012
Tmietransmembrane inner ear0.012
Stx4asyntaxin 4A (placental)0.012
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.012
Ptger1prostaglandin E receptor 1 (subtype EP1)0.012
Tmem176btransmembrane protein 176B0.012
Ephx1epoxide hydrolase 1, microsomal0.012
Campcathelicidin antimicrobial peptide0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
arpc1bactin related protein 2/3 complex, subunit 1B0.125
snx5sorting nexin 50.107
lrrc33leucine rich repeat containing 330.063
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.060
ctszcathepsin Z0.056
ptpn6protein tyrosine phosphatase, non-receptor type 60.035
cpne1copine I0.030
gmfgglia maturation factor, gamma0.027
sept2septin 20.023
snx4sorting nexin 40.022
cotl1coactosin-like 1 (Dictyostelium)0.019
cxcr3.2chemokine (C-X-C motif) receptor 3.20.016
pfn2profilin 20.016
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.016
ptprcprotein tyrosine phosphatase, receptor type, C0.015
atp6v1fATPase, H+ transporting, V1 subunit F0.015
copb1coatomer protein complex, subunit beta 10.014
psat1phosphoserine aminotransferase 10.014
wipi1WD repeat domain, phosphoinositide interacting 10.014
LOC100151049lysosomal-associated protein transmembrane 50.013
elovl1belongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b0.013
arcn1larchain 1 like0.012
atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.012
rab5cRAB5C, member RAS oncogene family0.012
copb2coatomer protein complex, subunit beta 20.012
pgdphosphogluconate hydrogenase0.011
fscn1fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)0.011
cltcaclathrin, heavy polypeptide a (Hc)0.011
vps35vacuolar protein sorting 35 (yeast)0.010
creb3l3lcAMP responsive element binding protein 3-like 3 like0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rab2Rab-protein 20.466
Rab6Rab-protein 60.424
Rab7Rab-protein 70.234
CG12004CG12004 gene product from transcript CG12004-RC0.116
locolocomotion defects0.043
RalaRas-related protein0.031
RhebCG1081 gene product from transcript CG1081-RA0.021
CG8974CG8974 gene product from transcript CG8974-RD0.020
Tis11Tis11 homolog0.017
TMS1CG4672 gene product from transcript CG4672-RA0.015
Vps16AVacuolar protein sorting 16A0.013
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.012
Mpk2CG5475 gene product from transcript CG5475-RB0.012
CG6364CG6364 gene product from transcript CG6364-RB0.012
CG15309CG15309 gene product from transcript CG15309-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SNX6sorting nexin 60.914
DNM2dynamin 20.375
VPS33Bvacuolar protein sorting 33 homolog B (yeast)0.369
RAB5ARAB5A, member RAS oncogene family0.330
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.240
GDI2GDP dissociation inhibitor 20.181
SNX33sorting nexin 330.157
GOLGA2golgin A20.155
ITSN1intersectin 1 (SH3 domain protein)0.149
OCRLoculocerebrorenal syndrome of Lowe0.147
FNBP1formin binding protein 10.131
GRB2growth factor receptor-bound protein 20.123
SH3KBP1SH3-domain kinase binding protein 10.083
ATF2activating transcription factor 20.079
FASLGFas ligand (TNF superfamily, member 6)0.053
TPM4tropomyosin 40.043
ADAM15ADAM metallopeptidase domain 150.039
EEA1early endosome antigen 10.032
AP1G1adaptor-related protein complex 1, gamma 1 subunit0.026
WASLWiskott-Aldrich syndrome-like0.019
PACSIN2protein kinase C and casein kinase substrate in neurons 20.019
RAB1ARAB1A, member RAS oncogene family0.018
VPS41vacuolar protein sorting 41 homolog (S. cerevisiae)0.017
DNM1dynamin 10.016
RAB1BRAB1B, member RAS oncogene family0.013
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.012
RAB6ARAB6A, member RAS oncogene family0.012
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.011
RAB11ARAB11A, member RAS oncogene family0.011
ARF4ADP-ribosylation factor 40.010
SH3GL2SH3-domain GRB2-like 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism