The network for 'positive regulation of transporter activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of transporter activity

Any process that activates or increases the activity of a transporter.

NameDescriptionProbabilityFunc Analog Organism
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.554
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.226
Shhsonic hedgehog0.192
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.153
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.135
Ikbkginhibitor of kappaB kinase gamma0.122
Ldb3LIM domain binding 30.101
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.086
Kcnk3potassium channel, subfamily K, member 30.083
Pdx1pancreatic and duodenal homeobox 10.069
Fgfr2fibroblast growth factor receptor 20.063
Emx1empty spiracles homolog 1 (Drosophila)0.058
Homer1homer homolog 1 (Drosophila)0.056
Rac1RAS-related C3 botulinum substrate 10.055
Prkceprotein kinase C, epsilon0.052
Grb10growth factor receptor bound protein 100.051
Per3period homolog 3 (Drosophila)0.051
Ghgrowth hormone0.050
Chukconserved helix-loop-helix ubiquitous kinase0.046
Cyldcylindromatosis (turban tumor syndrome)0.044
Gata6GATA binding protein 60.043
Dlg4discs, large homolog 4 (Drosophila)0.040
Tcf21transcription factor 210.040
Stim1stromal interaction molecule 10.040
Dag1dystroglycan 10.039
Nkx2-1NK2 homeobox 10.038
Ptpn11protein tyrosine phosphatase, non-receptor type 110.036
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.035
Nkx3-2NK3 homeobox 20.034
Sox9SRY-box containing gene 90.034
Stim2stromal interaction molecule 20.031
Tbx5T-box 50.030
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.029
RoraRAR-related orphan receptor alpha0.029
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.029
Foxb2forkhead box B20.028
Fgf8fibroblast growth factor 80.028
Ikbkbinhibitor of kappaB kinase beta0.027
Apcadenomatosis polyposis coli0.027
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.027
Casq2calsequestrin 20.026
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.026
Adrb3adrenergic receptor, beta 30.025
Ryr2ryanodine receptor 2, cardiac0.025
Hbb-b1hemoglobin, beta adult major chain0.025
Tbx1T-box 10.024
Myh10myosin, heavy polypeptide 10, non-muscle0.023
Epas1endothelial PAS domain protein 10.023
Bmpr1abone morphogenetic protein receptor, type 1A0.023
Maptmicrotubule-associated protein tau0.023
Pygmmuscle glycogen phosphorylase0.023
Prkcdprotein kinase C, delta0.022
Foxe1forkhead box E10.022
Lrp2low density lipoprotein receptor-related protein 20.021
Spnb1spectrin beta 10.021
Smad6MAD homolog 6 (Drosophila)0.021
Spock2sparc/osteonectin, cwcv and kazal-like domains proteoglycan 20.021
Sh3gl2SH3-domain GRB2-like 20.021
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.021
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.020
Shc3src homology 2 domain-containing transforming protein C30.020
Fgf12fibroblast growth factor 120.019
Itpr1inositol 1,4,5-trisphosphate receptor 10.019
Eporerythropoietin receptor0.019
Mybpc3myosin binding protein C, cardiac0.019
Spna2spectrin alpha 20.019
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.019
Ednraendothelin receptor type A0.019
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.019
Hand2heart and neural crest derivatives expressed transcript 20.018
Vegfavascular endothelial growth factor A0.018
Nkx2-6NK2 transcription factor related, locus 6 (Drosophila)0.018
Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin0.018
Scn1asodium channel, voltage-gated, type I, alpha0.018
Trp63transformation related protein 630.018
Sparcl1SPARC-like 10.017
Dtnadystrobrevin alpha0.017
Plp1proteolipid protein (myelin) 10.017
Spnb2spectrin beta 20.017
Fgf10fibroblast growth factor 100.017
Smad7MAD homolog 7 (Drosophila)0.017
Kcnd2potassium voltage-gated channel, Shal-related family, member 20.017
Iqcb1IQ calmodulin-binding motif containing 10.017
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.017
Hpcal4hippocalcin-like 40.017
Nkx6-1NK6 homeobox 10.017
Zfpm2zinc finger protein, multitype 20.016
Spna1spectrin alpha 10.016
Btrcbeta-transducin repeat containing protein0.016
Kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.016
Ift88intraflagellar transport 88 homolog (Chlamydomonas)0.016
Rock2Rho-associated coiled-coil containing protein kinase 20.016
Camk2bcalcium/calmodulin-dependent protein kinase II, beta0.016
Azi25-azacytidine induced gene 20.016
Fgf4fibroblast growth factor 40.016
Mesp1mesoderm posterior 10.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Nrx-1Neurexin 10.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GSTM1glutathione S-transferase mu 10.995
GSTM2glutathione S-transferase mu 2 (muscle)0.982
S100BS100 calcium binding protein B0.922
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.701
GSTM4glutathione S-transferase mu 40.700
TBX5T-box 50.626
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.402
NOXA1NADPH oxidase activator 10.397
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.337
NCF1neutrophil cytosolic factor 10.329
DTNAdystrobrevin, alpha0.323
FYNFYN oncogene related to SRC, FGR, YES0.282
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 50.260
TRPC1transient receptor potential cation channel, subfamily C, member 10.244
KLHL3kelch-like 3 (Drosophila)0.220
WNK1WNK lysine deficient protein kinase 10.205
ORAI1ORAI calcium release-activated calcium modulator 10.155
ITPR2inositol 1,4,5-trisphosphate receptor, type 20.138
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.133
MYOZ1myozenin 10.114
RYR2ryanodine receptor 2 (cardiac)0.112
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.108
ADORA2Aadenosine A2a receptor0.095
PDLIM1PDZ and LIM domain 10.089
MDM2Mdm2 p53 binding protein homolog (mouse)0.086
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.086
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.085
CHUKconserved helix-loop-helix ubiquitous kinase0.084
PKD1polycystic kidney disease 1 (autosomal dominant)0.084
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.083
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.081
MPDZmultiple PDZ domain protein0.079
GSTM3glutathione S-transferase mu 3 (brain)0.079
SQSTM1sequestosome 10.077
PRDX1peroxiredoxin 10.076
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.074
TSC22D4TSC22 domain family, member 40.067
SSTR2somatostatin receptor 20.067
MAPTmicrotubule-associated protein tau0.066
ACTN4actinin, alpha 40.064
AKAP6A kinase (PRKA) anchor protein 60.064
MYO10myosin X0.061
SORBS2sorbin and SH3 domain containing 20.061
MAPK4mitogen-activated protein kinase 40.060
PKD2polycystic kidney disease 2 (autosomal dominant)0.058
AKT1v-akt murine thymoma viral oncogene homolog 10.057
ATXN1ataxin 10.056
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.056
TRPC3transient receptor potential cation channel, subfamily C, member 30.055
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.053
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.053
TRIM63tripartite motif containing 630.052
SSTR3somatostatin receptor 30.052
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.051
TRIM29tripartite motif containing 290.049
GNB2guanine nucleotide binding protein (G protein), beta polypeptide 20.047
SCNN1Bsodium channel, nonvoltage-gated 1, beta0.046
DCTN1dynactin 10.046
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.046
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.045
MMP23Bmatrix metallopeptidase 23B0.045
PDZK1PDZ domain containing 10.043
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.043
ACTN1actinin, alpha 10.041
SOD1superoxide dismutase 1, soluble0.039
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.039
CDCP1CUB domain containing protein 10.039
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.038
SH3RF1SH3 domain containing ring finger 10.038
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.038
TP53tumor protein p530.037
HMG20Ahigh mobility group 20A0.037
DTNBdystrobrevin, beta0.037
BAG3BCL2-associated athanogene 30.036
MYH9myosin, heavy chain 9, non-muscle0.036
AFF4AF4/FMR2 family, member 40.035
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.035
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.035
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.035
PRKCZprotein kinase C, zeta0.035
TPM4tropomyosin 40.034
OXSR1oxidative-stress responsive 10.034
CDC37cell division cycle 37 homolog (S. cerevisiae)0.033
SYNMsynemin, intermediate filament protein0.033
ITPR3inositol 1,4,5-trisphosphate receptor, type 30.033
GPRASP1G protein-coupled receptor associated sorting protein 10.032
ZNF71zinc finger protein 710.032
PGAM1phosphoglycerate mutase 1 (brain)0.032
CASP3caspase 3, apoptosis-related cysteine peptidase0.029
S100A1S100 calcium binding protein A10.029
CHRNA4cholinergic receptor, nicotinic, alpha 40.029
MYOM2myomesin (M-protein) 2, 165kDa0.028
DISC1disrupted in schizophrenia 10.028
CYBAcytochrome b-245, alpha polypeptide0.027
CREBBPCREB binding protein0.027
SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 10.026
ILKintegrin-linked kinase0.026
MAP7D1MAP7 domain containing 10.026
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa2annexin A20.258
S100a8S100 calcium binding protein A80.105
S100a9S100 calcium binding protein A90.098
Lgals3lectin, galactoside-binding, soluble, 30.075
S100a6S100 calcium binding protein A60.074
Anxa1annexin A10.051
S100a10S100 calcium binding protein A100.039
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.030
Fgf14fibroblast growth factor 140.029
Slc6a17solute carrier family 6 (neurotransmitter transporter), member 170.022
Hpcal4hippocalcin-like 40.019
Gria1glutamate receptor, ionotropic, AMPA 10.017
AhnakAHNAK nucleoprotein0.016
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.016
Psma3proteasome (prosome, macropain) subunit, alpha type 30.015
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.014
Adrb3adrenergic, beta-3-, receptor0.014
Timp1TIMP metallopeptidase inhibitor 10.014
Ppardperoxisome proliferator-activated receptor delta0.014
Hprt1hypoxanthine phosphoribosyltransferase 10.014
Aqp4aquaporin 40.014
Pgcprogastricsin (pepsinogen C)0.013
Mgpmatrix Gla protein0.013
Rph3arabphilin 3A0.013
Rims1regulating synaptic membrane exocytosis 10.013
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.013
Nlgn2neuroligin 20.012
Mgst3microsomal glutathione S-transferase 30.012
Plp2proteolipid protein 2 (colonic epithelium-enriched)0.012
Dlg4discs, large homolog 4 (Drosophila)0.012
Ctrcchymotrypsin C (caldecrin)0.012
Spt1salivary protein 10.012
S100a4S100 calcium-binding protein A40.012
Egr3early growth response 30.012
Pmp22peripheral myelin protein 220.011
Accn2amiloride-sensitive cation channel 2, neuronal0.011
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.011
Chrnb4cholinergic receptor, nicotinic, beta 40.011
Olr416olfactory receptor 4160.011
Kcnt1potassium channel, subfamily T, member 10.010
Syt8synaptotagmin VIII0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism