The network for 'physiological muscle hypertrophy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

physiological muscle hypertrophy

The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.

NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.905
Apcadenomatosis polyposis coli0.754
Axin1axin 10.617
Agtr1aangiotensin II receptor, type 1a0.360
Leprleptin receptor0.298
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.176
Lrrk2leucine-rich repeat kinase 20.153
Lrp6low density lipoprotein receptor-related protein 60.136
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.132
Egfrepidermal growth factor receptor0.119
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.112
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.108
Epas1endothelial PAS domain protein 10.092
Gsk3bglycogen synthase kinase 3 beta0.089
Hif1ahypoxia inducible factor 1, alpha subunit0.088
Kif1bkinesin family member 1B0.068
Vav3vav 3 oncogene0.065
Ncoa1nuclear receptor coactivator 10.062
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.055
Mef2amyocyte enhancer factor 2A0.054
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.051
Ppargperoxisome proliferator activated receptor gamma0.049
Itgbl1integrin, beta-like 10.049
Vegfavascular endothelial growth factor A0.048
Hivep2human immunodeficiency virus type I enhancer binding protein 20.048
Smad3MAD homolog 3 (Drosophila)0.045
Srpxsushi-repeat-containing protein0.042
Slc23a2solute carrier family 23 (nucleobase transporters), member 20.039
Kcne4potassium voltage-gated channel, Isk-related subfamily, gene 40.039
Apoeapolipoprotein E0.039
Agtr2angiotensin II receptor, type 20.038
Col16a1collagen, type XVI, alpha 10.037
Adamts2a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20.037
Mtmr1myotubularin related protein 10.036
Scn7asodium channel, voltage-gated, type VII, alpha0.036
BrafBraf transforming gene0.036
Ptgs2prostaglandin-endoperoxide synthase 20.033
Tgfb1transforming growth factor, beta 10.032
Meox2mesenchyme homeobox 20.031
Cpzcarboxypeptidase Z0.031
Vav2vav 2 oncogene0.030
Igf1insulin-like growth factor 10.030
Hoxd8homeobox D80.029
Tfpi2tissue factor pathway inhibitor 20.028
Slc14a2solute carrier family 14 (urea transporter), member 20.027
Mapk9mitogen-activated protein kinase 90.027
Il6stinterleukin 6 signal transducer0.027
Egln3EGL nine homolog 3 (C. elegans)0.027
Adrb2adrenergic receptor, beta 20.026
Kpna1karyopherin (importin) alpha 10.026
Vdrvitamin D receptor0.026
Col6a3collagen, type VI, alpha 30.026
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.026
Adam17a disintegrin and metallopeptidase domain 170.026
Ror2receptor tyrosine kinase-like orphan receptor 20.026
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.025
Fbxo43F-box protein 430.025
Tcf7l2transcription factor 7-like 2, T-cell specific, HMG-box0.025
Col11a1collagen, type XI, alpha 10.024
Thbs2thrombospondin 20.024
Arntlaryl hydrocarbon receptor nuclear translocator-like0.024
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.024
Nf2neurofibromatosis 20.023
Wnk4WNK lysine deficient protein kinase 40.023
Slc12a1solute carrier family 12, member 10.023
Hipk3homeodomain interacting protein kinase 30.023
Gsk3aglycogen synthase kinase 3 alpha0.022
Fcnaficolin A0.022
Bmpr1abone morphogenetic protein receptor, type 1A0.022
Arid1bAT rich interactive domain 1B (SWI-like)0.022
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)0.022
Pde4dphosphodiesterase 4D, cAMP specific0.021
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.021
Angpt4angiopoietin 40.021
Gatad2bGATA zinc finger domain containing 2B0.020
Tnxbtenascin XB0.020
Atp8a1ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 10.020
Cxcl12chemokine (C-X-C motif) ligand 120.020
Crhcorticotropin releasing hormone0.019
Pcmtd1protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 10.019
Col4a4collagen, type IV, alpha 40.019
Nos3nitric oxide synthase 3, endothelial cell0.019
Dkk2dickkopf homolog 2 (Xenopus laevis)0.019
Crhr1corticotropin releasing hormone receptor 10.019
Pcsk5proprotein convertase subtilisin/kexin type 50.019
C1scomplement component 1, s subcomponent0.018
Rab10RAB10, member RAS oncogene family0.018
Cyp11b1cytochrome P450, family 11, subfamily b, polypeptide 10.018
Camk2dcalcium/calmodulin-dependent protein kinase II, delta0.017
Klhl24kelch-like 24 (Drosophila)0.017
Fibinfin bud initiation factor homolog (zebrafish)0.017
Pnpla2patatin-like phospholipase domain containing 20.017
C1qtnf3C1q and tumor necrosis factor related protein 30.017
Adam18a disintegrin and metallopeptidase domain 180.017
Fgf7fibroblast growth factor 70.017
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100362824caveolin 2-like0.041
Cav2caveolin 20.039
Rup2urinary protein 20.037
Vom2r27vomeronasal 2 receptor, 270.023
Cav1caveolin 1, caveolae protein0.023
Apohapolipoprotein H (beta-2-glycoprotein I)0.017
Spp2secreted phosphoprotein 20.016
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.016
Akr1c18aldo-keto reductase family 1, member C180.015
Procprotein C0.015
Lifleukemia inhibitory factor0.014
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.012
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.012
Nos3nitric oxide synthase 3, endothelial cell0.012
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.011
Cckarcholecystokinin A receptor0.011
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.011
Fdft1farnesyl diphosphate farnesyl transferase 10.011
Gria1glutamate receptor, ionotropic, AMPA 10.011
Hnmthistamine N-methyltransferase0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism