The network for 'endonucleolytic cleavage involved in rrna processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endonucleolytic cleavage involved in rrna processing

Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.

NameDescriptionProbabilityFunc Analog Organism
Gnl3guanine nucleotide binding protein-like 3 (nucleolar)0.758
Mybbp1aMYB binding protein (P160) 1a0.705
Wdr43WD repeat domain 430.615
Grwd1glutamate-rich WD repeat containing 10.510
Nop2NOP2 nucleolar protein homolog (yeast)0.414
Polr1bpolymerase (RNA) I polypeptide B0.264
Ddx21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.253
Rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.233
Utp20UTP20, small subunit (SSU) processome component, homolog (yeast)0.233
Eedembryonic ectoderm development0.225
Rrp9RRP9, small subunit (SSU) processome component, homolog (yeast)0.220
Tsr1TSR1, 20S rRNA accumulation, homolog (yeast)0.213
Ppanpeter pan homolog (Drosophila)0.200
Pprc1peroxisome proliferative activated receptor, gamma, coactivator-related 10.190
Smyd5SET and MYND domain containing 50.173
Mettl1methyltransferase like 10.172
Srmspermidine synthase0.163
Wdr46WD repeat domain 460.162
Ftsj3FtsJ homolog 3 (E. coli)0.158
Tex10testis expressed gene 100.136
Fam203afamily with sequence similarity 203, member A0.124
Pwp2PWP2 periodic tryptophan protein homolog (yeast)0.109
Rbm19RNA binding motif protein 190.108
Byslbystin-like0.096
Tbrg4transforming growth factor beta regulated gene 40.089
CebpzCCAAT/enhancer binding protein zeta0.084
Rrp15ribosomal RNA processing 15 homolog (S. cerevisiae)0.082
D19Bwg1357eDNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed0.072
Rrp1bribosomal RNA processing 1 homolog B (S. cerevisiae)0.069
Suz12suppressor of zeste 12 homolog (Drosophila)0.067
Nsun2NOL1/NOP2/Sun domain family member 20.065
Ccdc86coiled-coil domain containing 860.064
Cirh1acirrhosis, autosomal recessive 1A (human)0.063
Polr1apolymerase (RNA) I polypeptide A0.055
Elac2elaC homolog 2 (E. coli)0.055
2610027L16RikRIKEN cDNA 2610027L16 gene0.052
Eif1aeukaryotic translation initiation factor 1A0.049
Spata5spermatogenesis associated 50.048
Xpo5exportin 50.048
Nop14NOP14 nucleolar protein homolog (yeast)0.047
Pus7lpseudouridylate synthase 7 homolog (S. cerevisiae)-like0.040
Heatr1HEAT repeat containing 10.040
Pus1pseudouridine synthase 10.040
Noc4lnucleolar complex associated 4 homolog (S. cerevisiae)0.040
Ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.039
Brix1BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)0.038
Ddx51DEAD (Asp-Glu-Ala-Asp) box polypeptide 510.037
Gtpbp4GTP binding protein 40.036
Pdcd11programmed cell death 110.032
Nol8nucleolar protein 80.032
Ighimmunoglobulin heavy chain complex0.031
Bop1block of proliferation 10.030
Varsvalyl-tRNA synthetase0.028
Dnttip2deoxynucleotidyltransferase, terminal, interacting protein 20.028
Gnl2guanine nucleotide binding protein-like 2 (nucleolar)0.027
Noc3lnucleolar complex associated 3 homolog (S. cerevisiae)0.026
Dph2DPH2 homolog (S. cerevisiae)0.025
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.025
Zfp259zinc finger protein 2590.025
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.025
Eif3beukaryotic translation initiation factor 3, subunit B0.025
Kat2aK(lysine) acetyltransferase 2A0.025
Ddx20DEAD (Asp-Glu-Ala-Asp) box polypeptide 200.024
Ipo4importin 40.022
Nop56NOP56 ribonucleoprotein homolog (yeast)0.022
Nolc1nucleolar and coiled-body phosphoprotein 10.021
Aenapoptosis enhancing nuclease0.020
Mki67ipMki67 (FHA domain) interacting nucleolar phosphoprotein0.019
Btaf1BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)0.018
Dis3DIS3 mitotic control homolog (S. cerevisiae)0.018
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.018
Rbm34RNA binding motif protein 340.017
Imp4IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.017
Ino80eINO80 complex subunit E0.016
Ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.016
Exosc10exosome component 100.016
Dcaf13DDB1 and CUL4 associated factor 130.016
Trp53transformation related protein 530.016
Sdad1SDA1 domain containing 10.016
Rrs1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.015
Naa15N(alpha)-acetyltransferase 15, NatA auxiliary subunit0.015
Nufip1nuclear fragile X mental retardation protein interacting protein 10.014
Nubp1nucleotide binding protein 10.014
Atp13a1ATPase type 13A10.014
Ddx54DEAD (Asp-Glu-Ala-Asp) box polypeptide 540.014
Ccar1cell division cycle and apoptosis regulator 10.014
Mphosph10M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)0.013
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.013
Wdr75WD repeat domain 750.013
Tomm40translocase of outer mitochondrial membrane 40 homolog (yeast)0.012
Dohhdeoxyhypusine hydroxylase/monooxygenase0.012
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.012
Zzz3zinc finger, ZZ domain containing 30.012
Polr3apolymerase (RNA) III (DNA directed) polypeptide A0.011
Rcl1RNA terminal phosphate cyclase-like 10.011
Adrm1adhesion regulating molecule 10.011
Thoc5THO complex 50.011
Eif3aeukaryotic translation initiation factor 3, subunit A0.010
Ltv1LTV1 homolog (S. cerevisiae)0.010
Nle1notchless homolog 1 (Drosophila)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_C24H12.4Protein C24H12.40.860
W07E6.2Protein W07E6.20.760
tag-184Protein TAG-1840.727
rbd-1Protein RBD-10.713
F27C1.6Protein F27C1.60.705
K07H8.10Protein K07H8.100.643
CELE_T26G10.1Protein T26G10.10.553
Y53C12B.1Protein Y53C12B.10.510
pro-1Protein PRO-10.476
K07C5.4Protein K07C5.40.455
K12H4.3Protein K12H4.30.425
wdr-46Protein WDR-460.407
dao-5Protein DAO-50.393
ZK512.2Protein ZK512.20.388
ZK546.14Protein ZK546.140.372
CELE_T06E6.1Protein T06E6.10.367
rha-2Protein RHA-20.364
ZK792.5Protein ZK792.50.335
F54C9.9Protein F54C9.90.334
CELE_F23B12.7Protein F23B12.70.312
tag-151Protein TAG-1510.289
let-716Protein LET-7160.283
mrps-18CProtein MRPS-18C0.270
Y45F10D.7Protein Y45F10D.70.267
F55F8.2Protein F55F8.20.264
nol-1Protein NOL-10.251
nath-10Protein NATH-100.246
CELE_F53F4.11Protein F53F4.110.238
K04C2.2Protein K04C2.20.229
F09F7.3Protein F09F7.30.226
R02F2.7Protein R02F2.70.217
puf-12Protein PUF-120.214
fib-1Protein FIB-10.213
C53H9.2Protein C53H9.20.197
F58B3.4Protein F58B3.40.192
W04C9.4Protein W04C9.40.167
ZK686.2Protein ZK686.20.145
H06I04.3Protein H06I04.30.134
Y48G1A.4Protein Y48G1A.40.131
CELE_Y54H5A.1Protein Y54H5A.10.130
F49D11.10Protein F49D11.100.119
rrbs-1Protein RRBS-10.116
F25B5.5Protein F25B5.50.109
nol-5Protein NOL-50.107
CELE_Y48B6A.1Protein Y48B6A.10.105
R05D11.4Protein R05D11.40.102
lpd-2Protein LPD-20.101
C18A3.3Protein C18A3.30.100
C47E12.7Protein C47E12.70.093
tag-124Protein TAG-1240.088
Y66H1A.4Protein Y66H1A.40.087
ZK430.7Protein ZK430.70.087
T08B2.5Protein T08B2.50.084
ZK1127.4Protein ZK1127.40.082
C05C8.2Protein C05C8.20.073
K01G5.5Protein K01G5.50.068
Y46E12BL.2Protein Y46E12BL.20.068
toe-1Protein TOE-10.066
K05C4.5Protein K05C4.50.066
F18C12.3Protein F18C12.30.060
Y37E11B.5Protein Y37E11B.50.054
F13H8.2Protein F13H8.20.054
rpb-2Protein RPB-20.052
CELE_ZK795.3Protein ZK795.30.052
pro-2Protein PRO-20.051
T20B12.3Protein T20B12.30.050
C37H5.5Protein C37H5.50.050
CELE_Y52B11A.10Protein Y52B11A.100.048
tut-1Protein TUT-10.048
ngp-1Protein NGP-10.044
Y48E1A.1Protein Y48E1A.10.039
ears-1Protein EARS-10.039
eif-3.BProtein EIF-3.B0.037
F11A10.7Protein F11A10.70.036
Y73E7A.2Protein Y73E7A.20.034
glh-1Protein GLH-10.034
Y94H6A.5Protein Y94H6A.50.034
CELE_T04A8.6Protein T04A8.60.033
nst-1Protein NST-10.033
Y23H5B.6Protein Y23H5B.60.033
CELE_Y54E5B.2Protein Y54E5B.20.032
F55F8.3Protein F55F8.30.032
ama-1Protein AMA-10.032
lpd-6Protein LPD-60.030
T10B5.3Protein T10B5.30.030
ruvb-2Protein RUVB-20.029
T12E12.3Protein T12E12.30.028
F55A3.2Protein F55A3.20.028
dis-3Protein DIS-30.028
prmt-7Protein PRMT-70.027
fust-1Protein FUST-10.027
abcf-3Protein ABCF-30.024
egl-45Protein EGL-450.023
acin-1Protein ACIN-10.023
CELE_F07E5.5Protein F07E5.50.022
fbf-2Protein FBF-20.021
T23D8.3Protein T23D8.30.019
C44E4.4Protein C44E4.40.019
Y71G12B.8Protein Y71G12B.80.019
B0024.11Protein B0024.110.018
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
NOP1Nop1p0.967
FAF1Faf1p0.962
UTP18Utp18p0.941
SOF1Sof1p0.938
ENP1Enp1p0.916
BFR2Bfr2p0.896
ECM16Ecm16p0.891
MRD1Mrd1p0.865
MPP10Mpp10p0.862
KRR1Krr1p0.858
DIP2Dip2p0.813
KRE33Kre33p0.756
ENP2Enp2p0.754
UBP10Ubp10p0.740
IMP3Imp3p0.726
NOP8Nop8p0.700
UTP8Utp8p0.616
ESF2Esf2p0.600
UTP7Utp7p0.594
BUD21Bud21p0.579
UTP13Utp13p0.579
UTP11Utp11p0.569
BMS1Bms1p0.542
UTP4Utp4p0.540
NOP14Nop14p0.538
UTP25Utp25p0.526
SLX9Slx9p0.498
UTP23Utp23p0.486
RRP5Rrp5p0.442
UTP10Utp10p0.430
UTP21Utp21p0.411
UTP30Utp30p0.396
TRM112Trm112p0.391
NAN1Nan1p0.369
ESF1Esf1p0.368
PXR1Pxr1p0.347
RRP36Rrp36p0.346
SAS10Sas10p0.330
UTP9Utp9p0.325
IMP4Imp4p0.298
RRP14Rrp14p0.282
RPS17ARps17ap0.262
RRP12Rrp12p0.261
EMG1Emg1p0.256
LCP5Lcp5p0.250
NOP6Nop6p0.240
RPS18BRps18bp0.230
RIO2Rio2p0.230
NOP2Nop2p0.211
PWP2Pwp2p0.210
RIO1Rio1p0.201
RRP9Rrp9p0.197
TSR1Tsr1p0.188
GAR1Gar1p0.182
NOB1Nob1p0.157
RRP7Rrp7p0.152
NOP56Nop56p0.144
EBP2Ebp2p0.144
RIX7Rix7p0.143
PNO1Pno1p0.124
UTP14Utp14p0.120
DHR2Dhr2p0.119
RPS28BRps28bp0.116
EFG1Efg1p0.115
RPL22ARpl22ap0.115
FYV7Fyv7p0.114
RRP3Rrp3p0.112
URA2Ura2p0.106
NSA2Nsa2p0.104
LRP1Lrp1p0.102
UTP15Utp15p0.099
SRP21Srp21p0.093
FUN12Fun12p0.092
RPS30BRps30bp0.092
MTR3Mtr3p0.089
GLN1Gln1p0.087
SGD1Sgd1p0.086
CBF5Cbf5p0.085
GRC3Grc3p0.085
RPF1Rpf1p0.084
PRS2Prs2p0.083
RET1Ret1p0.081
NOC4Noc4p0.081
RPP2ARpp2ap0.079
RCL1Rcl1p0.078
FCF1Fcf1p0.078
NSP1Nsp1p0.077
DED1Ded1p0.074
RPL37ARpl37ap0.073
RPS4ARps4ap0.072
ROK1Rok1p0.072
RPS21ARps21ap0.072
RPA43Rpa43p0.072
RSA4Rsa4p0.071
FCF2Fcf2p0.070
RPS29ARps29ap0.070
NOP9Nop9p0.068
PRS3Prs3p0.068
UTP20Utp20p0.067
PRP28Prp28p0.067