The network for 'sperm motility' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sperm motility

Any process involved in the controlled movement of a sperm cell.

NameDescriptionProbabilityFunc Analog Organism
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.924
Pgk1phosphoglycerate kinase 10.908
Chrna9cholinergic receptor, nicotinic, alpha polypeptide 90.855
Aldoaaldolase A, fructose-bisphosphate0.834
Tpi1triosephosphate isomerase 10.662
Pkm2pyruvate kinase, muscle0.585
Pcsk4proprotein convertase subtilisin/kexin type 40.556
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.505
Gm5506predicted gene 55060.459
Tmem146transmembrane protein 1460.452
Akap4A kinase (PRKA) anchor protein 40.394
Gpi1glucose phosphate isomerase 10.387
Ryr1ryanodine receptor 1, skeletal muscle0.374
Gab1growth factor receptor bound protein 2-associated protein 10.361
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.359
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.349
Apoa1apolipoprotein A-I0.344
Atp1a4ATPase, Na+/K+ transporting, alpha 4 polypeptide0.342
Nab2Ngfi-A binding protein 20.336
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.288
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.257
Pfklphosphofructokinase, liver, B-type0.233
Allcallantoicase0.221
Akap3A kinase (PRKA) anchor protein 30.213
Cpeb3cytoplasmic polyadenylation element binding protein 30.210
Iqcb1IQ calmodulin-binding motif containing 10.203
Robo3roundabout homolog 3 (Drosophila)0.198
LOC100503041PDZ domain-containing protein 7-like0.190
Naa11N(alpha)-acetyltransferase 11, NatA catalytic subunit0.185
Alkanaplastic lymphoma kinase0.185
Drd4dopamine receptor D40.169
Chrna10cholinergic receptor, nicotinic, alpha polypeptide 100.167
Bsnbassoon0.150
Ecel1endothelin converting enzyme-like 10.144
Tulp2tubby-like protein 20.135
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.133
FosbFBJ osteosarcoma oncogene B0.131
Bmp8bbone morphogenetic protein 8b0.130
Tssk2testis-specific serine kinase 20.129
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.126
Ldhalactate dehydrogenase A0.116
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.114
Cdh23cadherin 23 (otocadherin)0.111
Pdha2pyruvate dehydrogenase E1 alpha 20.110
Dusp13dual specificity phosphatase 130.109
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.108
Il9interleukin 90.107
Nkx2-6NK2 transcription factor related, locus 6 (Drosophila)0.105
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.104
Syn1synapsin I0.104
Prm1protamine 10.103
Gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.102
Anxa2annexin A20.099
Fbxo15F-box protein 150.096
Brsk2BR serine/threonine kinase 20.096
FosFBJ osteosarcoma oncogene0.094
Dmrt1doublesex and mab-3 related transcription factor 10.091
Hsph1heat shock 105kDa/110kDa protein 10.090
Stk30serine/threonine kinase 300.089
Spag17sperm associated antigen 170.088
Hcn3hyperpolarization-activated, cyclic nucleotide-gated K+ 30.088
Aym1activator of yeast meiotic promoters 10.088
Npas1neuronal PAS domain protein 10.086
Inainternexin neuronal intermediate filament protein, alpha0.083
Stag3stromal antigen 30.083
Clcn1chloride channel 10.083
Nos1nitric oxide synthase 1, neuronal0.083
Acracrosin prepropeptide0.081
Dhhdesert hedgehog0.079
Cgaglycoprotein hormones, alpha subunit0.079
Catsper1cation channel, sperm associated 10.079
Dmc1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.078
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.078
Ptgs2prostaglandin-endoperoxide synthase 20.075
Hmgb4high-mobility group box 40.075
Rsph1radial spoke head 1 homolog (Chlamydomonas)0.073
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.073
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.073
Aff2AF4/FMR2 family, member 20.072
Stx1asyntaxin 1A (brain)0.072
Largelike-glycosyltransferase0.072
Stac2SH3 and cysteine rich domain 20.071
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.071
Ankrd36ankyrin repeat domain 360.071
Plac1placental specific protein 10.071
Anxa1annexin A10.070
Atcayataxia, cerebellar, Cayman type homolog (human)0.069
Lrrc46leucine rich repeat containing 460.068
Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 10.068
Amac1acyl-malonyl condensing enzyme 10.068
Oit1oncoprotein induced transcript 10.067
Myf6myogenic factor 60.066
Rhorhodopsin0.064
Btg2B-cell translocation gene 2, anti-proliferative0.064
Pdcd5programmed cell death 50.063
Gzmmgranzyme M (lymphocyte met-ase 1)0.063
Bcl2B-cell leukemia/lymphoma 20.063
Kif9kinesin family member 90.063
Kcnu1potassium channel, subfamily U, member 10.062
Ptprnprotein tyrosine phosphatase, receptor type, N0.062
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG34110CG34110 gene product from transcript CG34110-RC0.936
Roc1bCG16988 gene product from transcript CG16988-RA0.853
Pkd2Polycystic kidney disease gene-20.847
Prosalpha6TProteasome alpha6T subunit0.756
CG5155CG5155 gene product from transcript CG5155-RA0.623
NtlNeurotransmitter transporter-like0.533
Dpy-30L2Dpy-30-like 20.326
CG11253CG11253 gene product from transcript CG11253-RA0.270
CG10630CG10630 gene product from transcript CG10630-RA0.202
Cep135CG17081 gene product from transcript CG17081-RB0.152
CG7051CG7051 gene product from transcript CG7051-RA0.092
Cyt-c-dCytochrome c distal0.078
wtrwCG31284 gene product from transcript CG31284-RB0.063
eIF4E-3CG8023 gene product from transcript CG8023-RA0.055
CG13994CG13994 gene product from transcript CG13994-RA0.054
osm-1CG13809 gene product from transcript CG13809-RA0.049
CG12069CG12069 gene product from transcript CG12069-RA0.049
uncuncoordinated0.048
HtrA2CG8464 gene product from transcript CG8464-RA0.046
CG6308CG6308 gene product from transcript CG6308-RA0.035
CG6194CG6194 gene product from transcript CG6194-RA0.034
kl-3male fertility factor kl30.032
spag4sperm-associated antigen 40.031
CG40625CG40625 gene product from transcript CG40625-RB0.029
ana1anastral spindle 10.028
CG11885CG11885 gene product from transcript CG11885-RA0.025
mfrmisfire0.024
CG7781CG7781 gene product from transcript CG7781-RA0.023
Rrp6CG7292 gene product from transcript CG7292-RB0.023
comtcomatose0.022
CG1625CG1625 gene product from transcript CG1625-RB0.020
CG4288CG4288 gene product from transcript CG4288-RB0.018
CG4712CG4712 gene product from transcript CG4712-RB0.017
cp309CG33957 gene product from transcript CG33957-RB0.017
CG7795CG7795 gene product from transcript CG7795-RD0.017
Task6CG9637 gene product from transcript CG9637-RC0.016
CG5966CG5966 gene product from transcript CG5966-RA0.014
Tsp5DTetraspanin 5D0.014
HmrHybrid male rescue0.013
Cap-H2Chromosome associated protein H20.013
Klp68DKinesin-like protein at 68D0.013
AmaAmalgam0.012
ToporsTopoisomerase I-interacting protein0.012
Cpr56FCuticular protein 56F0.012
CG32685CG32685 gene product from transcript CG32685-RC0.011
CG13937CG13937 gene product from transcript CG13937-RD0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.624
SMURF1SMAD specific E3 ubiquitin protein ligase 10.327
HSPH1heat shock 105kDa/110kDa protein 10.327
HSPA8heat shock 70kDa protein 80.294
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.166
LIN9lin-9 homolog (C. elegans)0.158
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.075
PTPRJprotein tyrosine phosphatase, receptor type, J0.060
MYBL2v-myb myeloblastosis viral oncogene homolog (avian)-like 20.047
HSPE1heat shock 10kDa protein 1 (chaperonin 10)0.046
RANBP9RAN binding protein 90.040
RBL2retinoblastoma-like 2 (p130)0.040
ANXA1annexin A10.039
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.037
C3orf34chromosome 3 open reading frame 340.027
PTPN1protein tyrosine phosphatase, non-receptor type 10.024
S100A10S100 calcium binding protein A100.022
ITGB5integrin, beta 50.019
DVL3dishevelled, dsh homolog 3 (Drosophila)0.019
EIF5eukaryotic translation initiation factor 50.016
DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 60.015
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.014
FKBP4FK506 binding protein 4, 59kDa0.013
SLC28A1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.012
CD63CD63 molecule0.012
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.012
DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 10.012
BAG1BCL2-associated athanogene0.011
ANXA2annexin A20.011
HSPA4heat shock 70kDa protein 40.011
LIN52lin-52 homolog (C. elegans)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa5annexin A50.743
Anxa1annexin A10.209
S100a10S100 calcium binding protein A100.196
Itgb1integrin, beta 10.182
Anxa2annexin A20.147
Vimvimentin0.113
Capn2calpain 20.088
S100a11S100 calcium binding protein A11 (calizzarin)0.085
S100a6S100 calcium binding protein A60.043
Lgals3lectin, galactoside-binding, soluble, 30.035
Cd151CD151 molecule (Raph blood group)0.018
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.013
Cd9CD9 molecule0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism