The network for 'triglyceride rich lipoprotein particle remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

triglyceride rich lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.

NameDescriptionProbabilityFunc Analog Organism
Apoa1apolipoprotein A-I0.841
F12coagulation factor XII (Hageman factor)0.294
Nos3nitric oxide synthase 3, endothelial cell0.178
Apoc4apolipoprotein C-IV0.173
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.148
Ambpalpha 1 microglobulin/bikunin0.135
Lyz2lysozyme 20.131
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.129
Ldlrlow density lipoprotein receptor0.116
Apobapolipoprotein B0.112
Gcgrglucagon receptor0.112
F2coagulation factor II0.106
Leprleptin receptor0.104
Ahsgalpha-2-HS-glycoprotein0.104
Prodh2proline dehydrogenase (oxidase) 20.083
Plgplasminogen0.070
Ppargperoxisome proliferator activated receptor gamma0.064
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.061
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.058
Apomapolipoprotein M0.057
Apoa2apolipoprotein A-II0.052
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.049
Mt1metallothionein 10.045
Scd1stearoyl-Coenzyme A desaturase 10.045
Asgr2asialoglycoprotein receptor 20.043
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.038
Serpinc1serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 10.038
Fggfibrinogen gamma chain0.037
FasFas (TNF receptor superfamily member 6)0.035
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.034
Hgdhomogentisate 1, 2-dioxygenase0.033
Npc1Niemann Pick type C10.031
Aldobaldolase B, fructose-bisphosphate0.030
Hnf4ahepatic nuclear factor 4, alpha0.030
Rdh7retinol dehydrogenase 70.030
Lrp1low density lipoprotein receptor-related protein 10.029
Pzppregnancy zone protein0.027
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.027
Ptenphosphatase and tensin homolog0.025
Fgbfibrinogen beta chain0.024
Apoc3apolipoprotein C-III0.023
Dmgdhdimethylglycine dehydrogenase precursor0.023
Mbl2mannose-binding lectin (protein C) 20.021
Procprotein C0.019
Gcgroup specific component0.019
Itih1inter-alpha trypsin inhibitor, heavy chain 10.017
Apoa4apolipoprotein A-IV0.017
Rxraretinoid X receptor alpha0.017
Fgafibrinogen alpha chain0.017
Ghrgrowth hormone receptor0.016
Cps1carbamoyl-phosphate synthetase 10.016
Tgfb1transforming growth factor, beta 10.016
C3complement component 30.016
Itih4inter alpha-trypsin inhibitor, heavy chain 40.016
Lpin1lipin 10.015
Mmp9matrix metallopeptidase 90.015
Azgp1alpha-2-glycoprotein 1, zinc0.015
Abhd5abhydrolase domain containing 50.014
Hamphepcidin antimicrobial peptide0.014
Soat2sterol O-acyltransferase 20.014
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.014
Prnpprion protein0.014
Ces1ccarboxylesterase 1C0.013
Agxtalanine-glyoxylate aminotransferase0.013
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.013
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.013
Serpind1serine (or cysteine) peptidase inhibitor, clade D, member 10.013
Sstr3somatostatin receptor 30.013
Habp2hyaluronic acid binding protein 20.012
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.012
Hpxhemopexin0.012
Klf15Kruppel-like factor 150.011
H1fooH1 histone family, member O, oocyte-specific0.011
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.011
Apoc1apolipoprotein C-I0.011
Nos1nitric oxide synthase 1, neuronal0.011
Mosc1MOCO sulphurase C-terminal domain containing 10.011
C8gcomplement component 8, gamma polypeptide0.011
Cdhr5cadherin-related family member 50.011
Cyp2c70cytochrome P450, family 2, subfamily c, polypeptide 700.010
Nr0b2nuclear receptor subfamily 0, group B, member 20.010
Lect2leukocyte cell-derived chemotaxin 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
APOA1apolipoprotein A-I1.000
ALBalbumin0.999
HPhaptoglobin0.976
APOC1apolipoprotein C-I0.789
LCATlecithin-cholesterol acyltransferase0.711
A2Malpha-2-macroglobulin0.666
APOA2apolipoprotein A-II0.637
APOC3apolipoprotein C-III0.412
FGAfibrinogen alpha chain0.203
APOC2apolipoprotein C-II0.146
TTRtransthyretin0.087
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.043
APOBapolipoprotein B (including Ag(x) antigen)0.039
MDKmidkine (neurite growth-promoting factor 2)0.037
AHSGalpha-2-HS-glycoprotein0.032
TXNDC2thioredoxin domain containing 2 (spermatozoa)0.031
ECSITECSIT homolog (Drosophila)0.025
PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)0.020
RPL18Aribosomal protein L18a0.020
APOEapolipoprotein E0.019
FAM83Cfamily with sequence similarity 83, member C0.013
PLTPphospholipid transfer protein0.011
C1QCcomplement component 1, q subcomponent, C chain0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism