The network for 'positive regulation of rac protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of rac protein signal transduction

Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.

NameDescriptionProbabilityFunc Analog Organism
Ptenphosphatase and tensin homolog0.983
Rb1retinoblastoma 10.788
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.670
Trp53transformation related protein 530.654
Apcadenomatosis polyposis coli0.492
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.481
Ptpn11protein tyrosine phosphatase, non-receptor type 110.480
BrafBraf transforming gene0.472
Ctnnb1catenin (cadherin associated protein), beta 10.416
Egfrepidermal growth factor receptor0.411
Smad4MAD homolog 4 (Drosophila)0.385
Hif1ahypoxia inducible factor 1, alpha subunit0.294
Raf1v-raf-leukemia viral oncogene 10.251
Nos3nitric oxide synthase 3, endothelial cell0.183
Mdm2transformed mouse 3T3 cell double minute 20.134
Cdkn1bcyclin-dependent kinase inhibitor 1B0.127
Hprthypoxanthine guanine phosphoribosyl transferase0.103
Chukconserved helix-loop-helix ubiquitous kinase0.086
Tmem123transmembrane protein 1230.084
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.079
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.072
Nr3c1nuclear receptor subfamily 3, group C, member 10.070
Lrrc58leucine rich repeat containing 580.065
Rasip1Ras interacting protein 10.058
Grb2growth factor receptor bound protein 20.058
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.058
Itga6integrin alpha 60.055
Nrasneuroblastoma ras oncogene0.054
Tgfbr1transforming growth factor, beta receptor I0.054
Kitkit oncogene0.054
Smad2MAD homolog 2 (Drosophila)0.051
Cdkn2acyclin-dependent kinase inhibitor 2A0.049
Esamendothelial cell-specific adhesion molecule0.047
Shc1src homology 2 domain-containing transforming protein C10.047
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.046
Mtpnmyotrophin0.045
Kitlkit ligand0.045
Shank3SH3/ankyrin domain gene 30.045
Engendoglin0.043
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.041
Osbpl11oxysterol binding protein-like 110.041
Nf2neurofibromatosis 20.039
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.034
Mapre1microtubule-associated protein, RP/EB family, member 10.033
Sav1salvador homolog 1 (Drosophila)0.032
Errfi1ERBB receptor feedback inhibitor 10.031
Egfl7EGF-like domain 70.030
Rab5aRAB5A, member RAS oncogene family0.028
Eif1aeukaryotic translation initiation factor 1A0.028
Agfg1ArfGAP with FG repeats 10.028
Dync1i2dynein cytoplasmic 1 intermediate chain 20.027
Sox18SRY-box containing gene 180.026
Meox2mesenchyme homeobox 20.026
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.026
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.025
Eif2ak3eukaryotic translation initiation factor 2 alpha kinase 30.024
Abi1abl-interactor 10.024
Rfwd2ring finger and WD repeat domain 20.022
Xpaxeroderma pigmentosum, complementation group A0.022
Rxraretinoid X receptor alpha0.022
C78339expressed sequence C783390.021
Ranbp9RAN binding protein 90.020
Ptpn12protein tyrosine phosphatase, non-receptor type 120.020
Vhlvon Hippel-Lindau tumor suppressor0.020
Nf1neurofibromatosis 10.019
Csnk2bcasein kinase 2, beta polypeptide0.018
Ptp4a2protein tyrosine phosphatase 4a20.018
Nus1nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)0.018
Cldn5claudin 50.018
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.018
Tgfbr2transforming growth factor, beta receptor II0.018
Stxbp3asyntaxin binding protein 3A0.018
Col1a1collagen, type I, alpha 10.018
Trim33tripartite motif-containing 330.017
Brca1breast cancer 10.017
Zfp131zinc finger protein 1310.017
Ppargperoxisome proliferator activated receptor gamma0.017
Nptnneuroplastin0.017
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.016
Gja1gap junction protein, alpha 10.016
Zzz3zinc finger, ZZ domain containing 30.015
S100a13S100 calcium binding protein A130.015
Vegfavascular endothelial growth factor A0.015
Dennd4cDENN/MADD domain containing 4C0.014
Ythdf3YTH domain family 30.014
Rint1RAD50 interactor 10.014
Mffmitochondrial fission factor0.014
BC020535cDNA sequence BC0205350.014
Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 20.014
Nbnnibrin0.014
Hivep1human immunodeficiency virus type I enhancer binding protein 10.013
Pik3cbphosphatidylinositol 3-kinase, catalytic, beta polypeptide0.013
Eea1early endosome antigen 10.013
Stk11serine/threonine kinase 110.013
Tgfb1transforming growth factor, beta 10.013
Rock1Rho-associated coiled-coil containing protein kinase 10.013
Usp33ubiquitin specific peptidase 330.013
Nomo1nodal modulator 10.012
Eltd1EGF, latrophilin seven transmembrane domain containing 10.012
Notch1Notch gene homolog 1 (Drosophila)0.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
robo3roundabout homolog 30.687
robo1roundabout homolog 10.557
neo1neogenin 10.114
cdh2cadherin 2, neuronal0.081
lhx2bLIM homeobox 2b0.074
rc3rabconnectin 30.058
isl2aislet2a0.047
lingo1bleucine rich repeat and Ig domain containing 1b0.043
znf703zinc finger protein 7030.037
dag1dystroglycan 10.037
syne1aspectrin repeat containing, nuclear envelope 1a0.024
appaamyloid beta (A4) precursor protein a0.024
ppp3r1bprotein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b0.023
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.021
midnmidnolin0.020
zic5zic family member 5 (odd-paired homolog, Drosophila)0.017
prkar1aaprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a0.016
rgmaRGM domain family, member A0.015
sox11aSRY-box containing gene 11a0.015
kal1aKallmann syndrome 1a sequence0.014
limk2LIM domain kinase 20.013
slc8a4asolute carrier family 8 (sodium/calcium exchanger), member 4a0.012
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.012
mycbp2MYC binding protein 20.012
dusp6dual specificity phosphatase 60.012
tbx2bT-box 2b0.012
fgfr2fibroblast growth factor receptor 20.011
pdlim7PDZ and LIM domain 70.011
appbamyloid beta (A4) precursor protein b0.011
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.011
sec23aSec23 homolog A (S. cerevisiae)0.011
irx1airoquois homeobox protein 1, a0.011
mbnl2muscleblind-like 2 (Drosophila)0.011
hk1hexokinase 10.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.071
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism