The network for 'dna repair' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dna repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

NameDescriptionProbabilityFunc Analog Organism
Brca1breast cancer 11.000
Brca2breast cancer 21.000
Msh2mutS homolog 2 (E. coli)0.999
Atmataxia telangiectasia mutated homolog (human)0.999
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.998
Cdt1chromatin licensing and DNA replication factor 10.998
Rev1REV1 homolog (S. cerevisiae)0.996
Prim1DNA primase, p49 subunit0.994
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.973
Wdhd1WD repeat and HMG-box DNA binding protein 10.973
Smc3structural maintenace of chromosomes 30.971
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.969
Orc1origin recognition complex, subunit 10.969
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.965
Timelesstimeless homolog (Drosophila)0.955
Trp53transformation related protein 530.947
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.938
Hellshelicase, lymphoid specific0.930
Mdm4transformed mouse 3T3 cell double minute 40.927
Gmnngeminin0.926
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.925
E2f1E2F transcription factor 10.925
Pou5f1POU domain, class 5, transcription factor 10.921
Parp1poly (ADP-ribose) polymerase family, member 10.912
Nbnnibrin0.872
Terf1telomeric repeat binding factor 10.863
Ssrp1structure specific recognition protein 10.863
Dtldenticleless homolog (Drosophila)0.861
Ewsr1Ewing sarcoma breakpoint region 10.842
Mybl2myeloblastosis oncogene-like 20.812
Cdca5cell division cycle associated 50.803
Rad51RAD51 homolog (S. cerevisiae)0.797
Fancd2Fanconi anemia, complementation group D20.770
Cdk4cyclin-dependent kinase 40.763
Suz12suppressor of zeste 12 homolog (Drosophila)0.754
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.751
Rfc1replication factor C (activator 1) 10.738
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.736
Rttnrotatin0.734
Chek1checkpoint kinase 1 homolog (S. pombe)0.716
Dnmt1DNA methyltransferase (cytosine-5) 10.716
Pcnaproliferating cell nuclear antigen0.713
Mms22lMMS22-like, DNA repair protein0.705
Trim28tripartite motif-containing 280.686
Mlh1mutL homolog 1 (E. coli)0.684
Ep400E1A binding protein p4000.681
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.679
SkilSKI-like0.679
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.665
Xpaxeroderma pigmentosum, complementation group A0.662
Hdac1histone deacetylase 10.654
Sgol1shugoshin-like 1 (S. pombe)0.647
Foxo3forkhead box O30.642
Rfc2replication factor C (activator 1) 20.631
Siva1SIVA1, apoptosis-inducing factor0.630
Polepolymerase (DNA directed), epsilon0.620
Parp2poly (ADP-ribose) polymerase family, member 20.610
H2afzH2A histone family, member Z0.587
Supt16hsuppressor of Ty 16 homolog (S. cerevisiae)0.586
Anapc5anaphase-promoting complex subunit 50.582
Rfc4replication factor C (activator 1) 40.576
Rad54lRAD54 like (S. cerevisiae)0.575
Hspa14heat shock protein 140.565
Mcm10minichromosome maintenance deficient 10 (S. cerevisiae)0.554
Pnp2purine-nucleoside phosphorylase 20.552
WrnWerner syndrome homolog (human)0.546
Cenpkcentromere protein K0.539
Arid1bAT rich interactive domain 1B (SWI-like)0.524
BlmBloom syndrome, RecQ helicase-like0.521
Fen1flap structure specific endonuclease 10.514
Smc2structural maintenance of chromosomes 20.513
2700029M09RikRIKEN cDNA 2700029M09 gene0.512
Ncaphnon-SMC condensin I complex, subunit H0.508
Ezh2enhancer of zeste homolog 2 (Drosophila)0.507
CtcfCCCTC-binding factor0.501
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.498
Topbp1topoisomerase (DNA) II binding protein 10.497
H2afxH2A histone family, member X0.490
Ube2tubiquitin-conjugating enzyme E2T (putative)0.478
Kntc1kinetochore associated 10.473
Hat1histone aminotransferase 10.471
Smc1astructural maintenance of chromosomes 1A0.469
Lig1ligase I, DNA, ATP-dependent0.466
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.466
Syce2synaptonemal complex central element protein 20.454
Mre11ameiotic recombination 11 homolog A (S. cerevisiae)0.451
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.443
Pold3polymerase (DNA-directed), delta 3, accessory subunit0.437
Ncapd3non-SMC condensin II complex, subunit D30.432
Caprin2caprin family member 20.427
Pfn1profilin 10.421
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.418
Paip2polyadenylate-binding protein-interacting protein 20.416
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.416
Pole2polymerase (DNA directed), epsilon 2 (p59 subunit)0.413
Mis18bp1MIS18 binding protein 10.413
Tcfcp2l1transcription factor CP2-like 10.412
Rpa1replication protein A10.412
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.407
Hdac6histone deacetylase 60.407
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
his-16Protein HIS-160.872
his-3Protein HIS-30.847
his-1Protein HIS-10.635
his-47Protein HIS-470.598
his-42Protein HIS-420.484
his-45Protein HIS-450.442
F10C2.4Protein F10C2.40.336
his-5Protein HIS-50.298
hcp-4Protein HCP-40.248
his-2Protein HIS-20.226
his-39Protein HIS-390.213
F52B5.3Protein F52B5.30.208
his-9Protein HIS-90.201
dcr-1Protein DCR-10.199
npl-4.2Protein NPL-4.20.179
his-7Protein HIS-70.176
his-30Protein HIS-300.175
his-51Protein HIS-510.168
htz-1Protein HTZ-10.167
knl-1Protein KNL-10.159
gon-4Protein GON-40.158
his-64Protein HIS-640.153
tim-1Protein TIM-10.152
brd-1Protein BRD-10.145
mcm-5Protein MCM-50.144
polq-1Protein POLQ-10.144
cku-80Protein CKU-800.143
his-50Protein HIS-500.139
nasp-1Protein NASP-10.131
his-48Protein HIS-480.128
CELE_Y75B8A.25Protein Y75B8A.250.128
C32E8.5Protein C32E8.50.122
his-52Protein HIS-520.119
ima-2Protein IMA-20.117
ndc-80Protein NDC-800.116
his-46Protein HIS-460.113
his-38Protein HIS-380.106
his-63Protein HIS-630.105
his-61Protein HIS-610.095
CELE_K08F4.1Protein K08F4.10.094
his-31Protein HIS-310.094
orc-5Protein ORC-50.090
pme-3Protein PME-30.089
his-29Protein HIS-290.088
his-68Protein HIS-680.087
aly-2Protein ALY-20.081
his-26Protein HIS-260.080
his-62Protein HIS-620.079
pas-1Protein PAS-10.078
CELE_C29A12.1Protein C29A12.10.078
D1081.6Protein D1081.60.077
mis-12Protein MIS-120.074
spd-2Protein SPD-20.073
pabp-2Protein PABP-20.073
his-44Protein HIS-440.071
his-4Protein HIS-40.071
his-33Protein HIS-330.070
F54E12.2Protein F54E12.20.070
kle-2Protein KLE-20.069
B0412.3Protein B0412.30.067
Y55D9A.2Protein Y55D9A.20.067
D2085.4Protein D2085.40.066
msh-6Protein MSH-60.065
F25H5.5Protein F25H5.50.063
pme-1Protein PME-10.063
mbtr-1Protein MBTR-10.062
Y47D3A.29Protein Y47D3A.290.062
CELE_Y41E3.11Protein Y41E3.110.061
F33H2.5Protein F33H2.50.060
F32E10.5Protein F32E10.50.060
hcp-6Protein HCP-60.058
dpf-3Protein DPF-30.054
mac-1Protein MAC-10.054
mcm-6Protein MCM-60.054
his-6Protein HIS-60.053
H14E04.2Protein H14E04.20.053
C02F5.6Protein C02F5.60.053
F10B5.8Protein F10B5.80.052
his-14Protein HIS-140.052
pcn-1Protein PCN-10.052
icp-1Protein ICP-10.051
dcn-1Protein DCN-10.051
Y47D3A.28Protein Y47D3A.280.051
hsr-9Protein HSR-90.050
Y48G1C.1Protein Y48G1C.10.050
prp-8Protein PRP-80.049
mes-4Protein MES-40.047
H21P03.2Protein H21P03.20.047
CELE_C39E9.12Protein C39E9.120.047
C50F2.3Protein C50F2.30.047
snrp-200Protein SNRP-2000.046
npp-14Protein NPP-140.046
Y110A7A.9Protein Y110A7A.90.046
mcm-7Protein MCM-70.046
crn-3Protein CRN-30.045
moc-2Protein MOC-20.045
mrp-7Protein MRP-70.045
capg-2Protein CAPG-20.045
T14B4.1Protein T14B4.10.045
CELE_Y75B12B.1Protein Y75B12B.10.045
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wdhd1WD repeat and HMG-box DNA binding protein 10.248
pola2polymerase (DNA directed), alpha 20.245
wdr76WD repeat domain 760.089
chek1CHK1 checkpoint homolog (S. pombe)0.087
slbpstem-loop binding protein0.061
ddb2damage-specific DNA binding protein 20.060
naspnuclear autoantigenic sperm protein (histone-binding)0.058
fen1flap structure-specific endonuclease 10.056
cry5cryptochrome 50.052
pcnaproliferating cell nuclear antigen0.042
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.036
brca2breast cancer 2, early onset0.035
hat1histone acetyltransferase 10.032
palb2partner and localizer of BRCA20.032
si:dkey-258f14.5si:dkey-258f14.50.029
dnmt1DNA (cytosine-5-)-methyltransferase 10.027
zgc:101661zgc:1016610.023
fanclFanconi anemia, complementation group L0.023
hirip3HIRA interacting protein 30.022
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.022
tefthyrotroph embryonic factor0.021
dutdUTP pyrophosphatase0.021
gins2GINS complex subunit 20.020
suv39h1bsuppressor of variegation 3-9 homolog 1b0.018
ube2iubiquitin-conjugating enzyme E2I0.018
vcpvalosin containing protein0.018
xpcxeroderma pigmentosum, complementation group C0.018
sass6spindle assembly 6 homolog (C. elegans)0.018
zgc:56197zgc:561970.018
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.018
fanciFanconi anemia, complementation group I0.018
per2period homolog 2 (Drosophila)0.017
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae)0.016
blmhbleomycin hydrolase0.016
rfc5replication factor C (activator 1) 50.016
pola1polymerase (DNA directed), alpha 10.016
mybl2myeloblastosis oncogene-like 20.014
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.014
hellshelicase, lymphoid-specific0.013
cry-dashcryptochrome DASH0.013
msh2mutS homolog 2 (E. coli)0.013
cdk2cyclin-dependent kinase 20.013
hmgb2bhigh-mobility group box 2b0.013
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.012
hoxa13ahomeo box A13a0.012
traipTRAF-interacting protein0.012
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.012
eif4heukaryotic translation initiation factor 4h0.012
asf1bbASF1 anti-silencing function 1 homolog Bb0.011
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.011
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.011
paxip1PAX interacting (with transcription-activation domain) protein 10.010
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.010
rap1aRAP1A, member of RAS oncogene family0.010
psmb3proteasome (prosome, macropain) subunit, beta type, 30.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mus205mutagen-sensitive 2050.999
rad50CG6339 gene product from transcript CG6339-RD0.999
hayhaywire0.997
okrokra0.996
DNApol-etaCG7143 gene product from transcript CG7143-RA0.995
lokloki0.986
Brca2Breast cancer 2, early onset homolog0.981
mus101mutagen-sensitive 1010.979
RpA-70Replication Protein A 700.977
E(z)Enhancer of zeste0.949
mus209mutagen-sensitive 2090.943
RecQ5homolog of RecQ0.937
Rev1CG12189 gene product from transcript CG12189-RA0.937
Mcm2Minichromosome maintenance 20.929
mus201mutagen-sensitive 2010.887
Smc5CG32438 gene product from transcript CG32438-RE0.884
CG5524CG5524 gene product from transcript CG5524-RA0.877
mus210mutagen-sensitive 2100.870
IrbpInverted repeat-binding protein0.816
Ercc1CG10215 gene product from transcript CG10215-RA0.804
RfC4Replication factor C subunit 40.794
mei-41meiotic 410.724
CG9576CG9576 gene product from transcript CG9576-RA0.715
p53CG33336 gene product from transcript CG33336-RB0.682
Mcm3Minichromosome maintenance 30.657
tefutelomere fusion0.635
mus308mutagen-sensitive 3080.620
mus304mutagen-sensitive 3040.617
grogroucho0.554
Mlh1CG11482 gene product from transcript CG11482-RA0.550
Mcm7Minichromosome maintenance 70.539
RnrLRibonucleoside diphosphate reductase large subunit0.526
fzyfizzy0.495
spn-Bspindle B0.493
Lig4Ligase40.480
Rpn3Regulatory particle non-ATPase 30.463
RPA2Replication protein A20.395
mei-9meiotic 90.390
Rpn1CG7762 gene product from transcript CG7762-RA0.373
SsrpStructure specific recognition protein0.367
skpACG16983 gene product from transcript CG16983-RD0.364
CG14814CG14814 gene product from transcript CG14814-RA0.360
DNApol-alpha73DNA polymerase alpha 73kD0.352
Rpn9CG10230 gene product from transcript CG10230-RB0.352
WRNexoWRN exonuclease0.348
nbsCG6754 gene product from transcript CG6754-RC0.338
mus301mutagen-sensitive 3010.335
Mcm5Minichromosome maintenance 50.334
mspsmini spindles0.316
CG5003CG5003 gene product from transcript CG5003-RA0.310
mofmales absent on the first0.305
Fancd2CG17269 gene product from transcript CG17269-RA0.299
spn-Espindle E0.291
stwlstonewall0.282
RfC38Replication factor C 38kD subunit0.276
ik2IkappaB kinase-like 20.275
CG5602CG5602 gene product from transcript CG5602-RA0.265
CG8142CG8142 gene product from transcript CG8142-RA0.264
CSN4COP9 complex homolog subunit 40.263
Cks30ACyclin-dependent kinase subunit 30A0.256
CDC45LCG3658 gene product from transcript CG3658-RA0.250
mre11meiotic recombination 110.246
Tfb1CG8151 gene product from transcript CG8151-RB0.241
Psf1CG9187 gene product from transcript CG9187-RA0.240
CG13350CG13350 gene product from transcript CG13350-RA0.234
mus309mutagen-sensitive 3090.207
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.203
Jafrac1thioredoxin peroxidase 10.200
l(2)dtllethal-(2)-denticleless0.198
Ku80CG18801 gene product from transcript CG18801-RA0.192
eastenhanced adult sensory threshold0.175
Cul-3Cullin-30.173
D1D1 chromosomal protein0.172
ranshiCG9793 gene product from transcript CG9793-RA0.169
ash2absent, small, or homeotic discs 20.168
Pros54Proteasome 54kD subunit0.167
RfC3Replication factor C subunit 30.166
Hus1-likeCG2525 gene product from transcript CG2525-RA0.164
dre4CG1828 gene product from transcript CG1828-RB0.162
CG2694CG2694 gene product from transcript CG2694-RA0.162
His2AvHistone H2A variant0.156
Chrac-14CG13399 gene product from transcript CG13399-RA0.155
RecQ4CG7487 gene product from transcript CG7487-RA0.151
CG5924CG5924 gene product from transcript CG5924-RA0.150
sleslender lobes0.142
mad2CG17498 gene product from transcript CG17498-RA0.142
droshaCG8730 gene product from transcript CG8730-RA0.141
BRWD3CG31132 gene product from transcript CG31132-RA0.140
HmgDHigh mobility group protein D0.135
mus312mutagen-sensitive 3120.132
CkIIbetaCasein kinase II beta subunit0.132
Bap55Brahma associated protein 55kD0.123
spn-Aspindle A0.123
CG14965CG14965 gene product from transcript CG14965-RA0.123
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.122
CG5931CG5931 gene product from transcript CG5931-RA0.122
Rpt1CG1341 gene product from transcript CG1341-RA0.119
CG4771CG4771 gene product from transcript CG4771-RA0.119
MED17Mediator complex subunit 170.119
desat1CG5887 gene product from transcript CG5887-RA0.119
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BRCA1breast cancer 1, early onset1.000
PCNAproliferating cell nuclear antigen1.000
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)1.000
TP53tumor protein p531.000
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 41.000
BLMBloom syndrome, RecQ helicase-like1.000
PARP1poly (ADP-ribose) polymerase 11.000
H2AFXH2A histone family, member X1.000
MDM2Mdm2 p53 binding protein homolog (mouse)1.000
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)1.000
FANCAFanconi anemia, complementation group A1.000
FEN1flap structure-specific endonuclease 10.999
MDC1mediator of DNA-damage checkpoint 10.999
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.999
MSH6mutS homolog 6 (E. coli)0.999
CHEK1CHK1 checkpoint homolog (S. pombe)0.998
NBNnibrin0.998
RAD50RAD50 homolog (S. cerevisiae)0.997
RAD18RAD18 homolog (S. cerevisiae)0.997
RPA1replication protein A1, 70kDa0.996
BRCA2breast cancer 2, early onset0.996
DTLdenticleless homolog (Drosophila)0.995
HIST1H3Dhistone cluster 1, H3d0.994
SLX4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)0.994
CHEK2CHK2 checkpoint homolog (S. pombe)0.992
RAD51CRAD51 homolog C (S. cerevisiae)0.990
HIST1H2BGhistone cluster 1, H2bg0.988
BARD1BRCA1 associated RING domain 10.987
HIST1H2BDhistone cluster 1, H2bd0.987
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.982
RFC2replication factor C (activator 1) 2, 40kDa0.982
RAD1RAD1 homolog (S. pombe)0.980
FGFR2fibroblast growth factor receptor 20.980
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.979
CHAF1Achromatin assembly factor 1, subunit A (p150)0.978
EXO1exonuclease 10.978
XRCC1X-ray repair complementing defective repair in Chinese hamster cells 10.974
C19orf39chromosome 19 open reading frame 390.973
CREBBPCREB binding protein0.972
RB1retinoblastoma 10.972
GINS2GINS complex subunit 2 (Psf2 homolog)0.970
RPA3replication protein A3, 14kDa0.967
HIST1H1Chistone cluster 1, H1c0.967
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.965
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.959
MCM5minichromosome maintenance complex component 50.958
UCHL5ubiquitin carboxyl-terminal hydrolase L50.958
WRNWerner syndrome, RecQ helicase-like0.957
BRCC3BRCA1/BRCA2-containing complex, subunit 30.957
DDB1damage-specific DNA binding protein 1, 127kDa0.952
RAD23BRAD23 homolog B (S. cerevisiae)0.951
HIST1H2AEhistone cluster 1, H2ae0.948
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 40.948
ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 60.942
GTF2H1general transcription factor IIH, polypeptide 1, 62kDa0.938
RFC5replication factor C (activator 1) 5, 36.5kDa0.936
MCM2minichromosome maintenance complex component 20.936
SMC1Astructural maintenance of chromosomes 1A0.935
HIST1H2BFhistone cluster 1, H2bf0.930
HIST1H2AChistone cluster 1, H2ac0.928
EP300E1A binding protein p3000.923
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.921
APTXaprataxin0.911
RPA2replication protein A2, 32kDa0.908
ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.908
POLD3polymerase (DNA-directed), delta 3, accessory subunit0.906
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.900
CDC6cell division cycle 6 homolog (S. cerevisiae)0.899
MCM6minichromosome maintenance complex component 60.899
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.892
PLK1polo-like kinase 10.890
POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa0.885
RFC4replication factor C (activator 1) 4, 37kDa0.885
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.882
UBCubiquitin C0.880
HIST2H2BEhistone cluster 2, H2be0.880
HDAC1histone deacetylase 10.878
HIST1H2BIhistone cluster 1, H2bi0.876
PNKPpolynucleotide kinase 3'-phosphatase0.874
XPCxeroderma pigmentosum, complementation group C0.874
POLHpolymerase (DNA directed), eta0.871
CHD4chromodomain helicase DNA binding protein 40.868
BRIP1BRCA1 interacting protein C-terminal helicase 10.854
HIST1H2BEhistone cluster 1, H2be0.854
MTA1metastasis associated 10.849
RNF11ring finger protein 110.845
ACTL6Aactin-like 6A0.840
CDK2cyclin-dependent kinase 20.838
MCM4minichromosome maintenance complex component 40.837
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.828
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)0.815
CDT1chromatin licensing and DNA replication factor 10.809
DAXXdeath-domain associated protein0.808
E2F1E2F transcription factor 10.807
HIST1H2BHhistone cluster 1, H2bh0.802
FANCD2Fanconi anemia, complementation group D20.799
CCNE1cyclin E10.797
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.796
RAD51AP1RAD51 associated protein 10.787
RAD51L3RAD51-like 3 (S. cerevisiae)0.780
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Actbactin, beta0.022
Actg1actin, gamma 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
POL30Pol30p1.000
RAD9Rad9p1.000
RAD1Rad1p1.000
RFA1Rfa1p1.000
RAD18Rad18p0.999
RAD53Rad53p0.999
SRS2Srs2p0.999
CTF4Ctf4p0.999
RAD5Rad5p0.999
RAD54Rad54p0.999
MSH6Msh6p0.998
RAD24Rad24p0.998
RAD50Rad50p0.997
RAD27Rad27p0.997
ELG1Elg1p0.997
REV3Rev3p0.997
RAD23Rad23p0.997
SMC6Smc6p0.996
HHF1Hhf1p0.995
MSH2Msh2p0.994
XRS2Xrs2p0.992
RAD14Rad14p0.990
YAF9Yaf9p0.990
DDC1Ddc1p0.988
EAF1Eaf1p0.987
RAD52Rad52p0.985
APN1Apn1p0.985
SMC5Smc5p0.984
EAF5Eaf5p0.984
RAD10Rad10p0.984
RAD57Rad57p0.983
MLH1Mlh1p0.983
SGS1Sgs1p0.980
POL31Pol31p0.980
POL12Pol12p0.979
RAD4Rad4p0.970
MUS81Mus81p0.970
DUN1Dun1p0.969
RAD16Rad16p0.968
ARP4Arp4p0.967
RAD17Rad17p0.967
SLD5Sld5p0.967
NSE3Nse3p0.967
CDC45Cdc45p0.957
ASF1Asf1p0.955
MRC1Mrc1p0.955
POL2Pol2p0.950
MRE11Mre11p0.946
SWC4Swc4p0.945
EPL1Epl1p0.942
RPN1Rpn1p0.939
RAD51Rad51p0.938
MMS21Mms21p0.936
RTF1Rtf1p0.928
PMS1Pms1p0.918
MEC3Mec3p0.916
DNL4Dnl4p0.914
MCM2Mcm2p0.911
ESA1Esa1p0.908
SHU1Shu1p0.907
PSF1Psf1p0.905
RTT107Rtt107p0.897
MCM4Mcm4p0.889
NTG2Ntg2p0.887
PSY3Psy3p0.881
RTT109Rtt109p0.874
MCM5Mcm5p0.870
POL3Pol3p0.861
MEC1Mec1p0.854
CSM3Csm3p0.847
HTB1Htb1p0.845
SPT16Spt16p0.843
RAD3Rad3p0.823
MCM6Mcm6p0.820
LIF1Lif1p0.818
RAD7Rad7p0.818
NPL6Npl6p0.818
RAD59Rad59p0.812
INO80Ino80p0.810
POL1Pol1p0.807
MCM3Mcm3p0.804
GIN4Gin4p0.802
RAD6Rad6p0.797
NTG1Ntg1p0.794
SWI3Swi3p0.790
RSC8Rsc8p0.788
POL32Pol32p0.783
POB3Pob3p0.782
HTA1Hta1p0.778
UBR1Ubr1p0.771
EAF7Eaf7p0.767
SSL1Ssl1p0.763
DMC1Dmc1p0.757
PIF1Pif1p0.738
SLX8Slx8p0.737
TOP3Top3p0.727
DEF1Def1p0.727
YAP1Yap1p0.721
MPH1Mph1p0.711
IRR1Irr1p0.706