The network for 'positive regulation of heat generation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of heat generation

Any process that activates or increases the rate or extent of heat generation.

NameDescriptionProbabilityFunc Analog Organism
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.969
Map3k14mitogen-activated protein kinase kinase kinase 140.842
Ltalymphotoxin A0.813
Tnftumor necrosis factor0.747
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.309
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.273
Ptgs2prostaglandin-endoperoxide synthase 20.148
Ltblymphotoxin B0.133
Casp4caspase 4, apoptosis-related cysteine peptidase0.125
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.107
Il7interleukin 70.096
Cxcl13chemokine (C-X-C motif) ligand 130.088
Ikzf1IKAROS family zinc finger 10.083
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.079
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.077
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.061
Cxcr5chemokine (C-X-C motif) receptor 50.058
Il1binterleukin 1 beta0.040
Ifnginterferon gamma0.032
Il6interleukin 60.028
Il1r1interleukin 1 receptor, type I0.026
Toxthymocyte selection-associated high mobility group box0.026
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.020
Cd40CD40 antigen0.017
Nos2nitric oxide synthase 2, inducible0.017
Il1ainterleukin 1 alpha0.017
Il4interleukin 40.016
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.016
Socs1suppressor of cytokine signaling 10.014
Ccr1chemokine (C-C motif) receptor 10.013
Cd40lgCD40 ligand0.012
Rem1rad and gem related GTP binding protein 10.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Il1binterleukin 1 beta0.297
Ccl2chemokine (C-C motif) ligand 20.095
Ccl3chemokine (C-C motif) ligand 30.057
Ccl4chemokine (C-C motif) ligand 40.056
Cd14CD14 molecule0.042
Xcl1chemokine (C motif) ligand 10.023
Prf1perforin 1 (pore forming protein)0.023
Klrd1killer cell lectin-like receptor, subfamily D, member 10.023
RT1-BaRT1 class II, locus Ba0.015
Cxcl10chemokine (C-X-C motif) ligand 100.014
Il1ainterleukin 1 alpha0.014
Tlr2toll-like receptor 20.013
Fcn1ficolin (collagen/fibrinogen domain containing) 10.012
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.012
Tgm1transglutaminase 1, K polypeptide0.012
Tlr7toll-like receptor 70.011
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.011
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism