The network for 'negative regulation of dna recombination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of dna recombination

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.

NameDescriptionProbabilityFunc Analog Organism
Hist1h2bchistone cluster 1, H2bc0.101
Card11caspase recruitment domain family, member 110.099
Trp53transformation related protein 530.093
Gli2GLI-Kruppel family member GLI20.086
Terf1telomeric repeat binding factor 10.081
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.076
Tcfcp2l1transcription factor CP2-like 10.056
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.053
Pou5f1POU domain, class 5, transcription factor 10.043
Xpaxeroderma pigmentosum, complementation group A0.042
Pgrmc1progesterone receptor membrane component 10.041
Brca2breast cancer 20.035
Ighimmunoglobulin heavy chain complex0.035
Ahraryl-hydrocarbon receptor0.032
Wdr75WD repeat domain 750.030
Stat5asignal transducer and activator of transcription 5A0.030
Stk11serine/threonine kinase 110.027
Chd1lchromodomain helicase DNA binding protein 1-like0.027
Itfg1integrin alpha FG-GAP repeat containing 10.026
Smad4MAD homolog 4 (Drosophila)0.023
Foxp2forkhead box P20.023
Foxp1forkhead box P10.023
Rc3h1RING CCCH (C3H) domains 10.021
Eri2exoribonuclease 20.021
Map3k14mitogen-activated protein kinase kinase kinase 140.020
TcraT-cell receptor alpha chain0.020
Men1multiple endocrine neoplasia 10.019
Tmem30atransmembrane protein 30A0.019
Exosc8exosome component 80.019
Nvlnuclear VCP-like0.019
Itm2bintegral membrane protein 2B0.018
Rttnrotatin0.018
Tpp1tripeptidyl peptidase I0.018
Ttc7tetratricopeptide repeat domain 70.017
Orc2origin recognition complex, subunit 20.017
Lrrc40leucine rich repeat containing 400.016
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.016
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.015
Dhfrdihydrofolate reductase0.015
Dsn1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)0.015
Tsntranslin0.014
Nptnneuroplastin0.014
Dutdeoxyuridine triphosphatase0.014
Shesrc homology 2 domain-containing transforming protein E0.014
MtbpMdm2, transformed 3T3 cell double minute p53 binding protein0.014
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.013
C78339expressed sequence C783390.013
Tnftumor necrosis factor0.013
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.013
Meox2mesenchyme homeobox 20.013
Cpsf3cleavage and polyadenylation specificity factor 30.012
Kdm1alysine (K)-specific demethylase 1A0.012
Zscan4bzinc finger and SCAN domain containing 4B0.012
Bach2BTB and CNC homology 20.012
Sox18SRY-box containing gene 180.012
Il4interleukin 40.012
Clcc1chloride channel CLIC-like 10.012
Rnf103ring finger protein 1030.011
Msh2mutS homolog 2 (E. coli)0.011
Pms2postmeiotic segregation increased 2 (S. cerevisiae)0.011
Tm2d2TM2 domain containing 20.010
Parnpoly(A)-specific ribonuclease (deadenylation nuclease)0.010
Pold3polymerase (DNA-directed), delta 3, accessory subunit0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
prg-2Protein PRG-20.109
pcaf-1Protein PCAF-10.051
B0035.6Protein B0035.60.047
acly-2Protein ACLY-20.042
rad-54Protein RAD-540.031
F31C3.3Protein F31C3.30.029
qns-1Protein QNS-10.023
K06A5.1Protein K06A5.10.022
F55A12.5Protein F55A12.50.022
M01A10.1Protein M01A10.10.021
glp-1Protein GLP-10.021
F22B3.4Protein F22B3.40.019
msh-6Protein MSH-60.018
glh-4Protein GLH-40.018
F28C6.4Protein F28C6.40.017
tag-315Protein TAG-3150.015
rme-2Protein RME-20.015
B0001.2Protein B0001.20.014
F33H2.2Protein F33H2.20.013
T23G4.3Protein T23G4.30.012
ani-2Protein ANI-20.012
sep-1Protein SEP-10.012
F46F11.6Protein F46F11.60.012
xnd-1Protein XND-10.012
meg-1Protein MEG-10.012
mtm-1Protein MTM-10.011
mrp-7Protein MRP-70.011
CELE_C36A4.5Protein C36A4.50.011
F25H5.5Protein F25H5.50.011
R10H10.7Protein R10H10.70.011
CELE_Y57A10A.13Protein Y57A10A.130.011
ztf-15Protein ZTF-150.011
age-1Protein AGE-10.011
htp-3Protein HTP-30.010
wrn-1Protein WRN-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
piwil1piwi-like 1 (Drosophila)0.904
nanos3nanos homolog 30.785
fanclFanconi anemia, complementation group L0.778
brca2breast cancer 2, early onset0.437
dnddead end0.364
blmBloom syndrome0.328
rnf17ring finger protein 170.303
tbpl2TATA box binding protein like 20.260
vasavasa homolog0.239
recql5RecQ protein-like 50.195
tdrd1tudor domain containing 10.191
otulOTU like protein0.177
hspb11heat shock protein, alpha-crystallin-related, b110.148
msh2mutS homolog 2 (E. coli)0.098
zgc:193933zgc:1939330.092
bmpr1bbbone morphogenetic protein receptor, type 1bb0.084
henmt1HEN1 methyltransferase homolog 1 (Arabidopsis)0.080
syce2synaptonemal complex central element protein 20.074
zorbaOrb/CPEB-related RNA-binding protein0.070
sycp3lsynaptonemal complex protein 3 like0.067
mre11ameiotic recombination 11 homolog A (S. cerevisiae)0.065
mlh1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.065
lsm14bLSM14B, SCD6 homolog B (S. cerevisiae)0.055
vtg1vitellogenin 10.051
setdb2SET domain, bifurcated 20.050
fasFas (TNF receptor superfamily, member 6)0.046
dnmt1DNA (cytosine-5-)-methyltransferase 10.046
bucbucky ball0.044
ercc2excision repair cross-complementing rodent repair deficiency, complementation group 20.043
amhanti-Mullerian hormone0.037
inppl1ainositol polyphosphate phosphatase-like 1a0.033
tdrd7tudor domain containing 70.032
asz1ankyrin repeat, SAM and basic leucine zipper domain containing 10.030
hspb2heat shock protein, alpha-crystallin-related, b20.030
zgc:92648zgc:926480.030
mcm4MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)0.029
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.029
zgc:66313zgc:663130.026
mybl2myeloblastosis oncogene-like 20.024
eomesaeomesodermin homolog a0.023
orgoogenesis-related gene0.023
cpa4carboxypeptidase A40.022
timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.021
epoerythropoietin0.021
si:ch211-1n9.7si:ch211-1n9.70.021
dlstdihydrolipoamide S-succinyltransferase0.020
zgc:103482zgc:1034820.020
scn1asodium channel, voltage-gated, type I, alpha0.020
cx45.6connexin 45.60.020
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.020
phophoenix0.018
msh6mutS homolog 6 (E. coli)0.017
zgc:110434zgc:1104340.017
setd6SET domain containing 60.017
npatnuclear protein, ataxia-telangiectasia locus0.017
trmt2atrm2 tRNA methyltransferase 2 homolog A (S. cerevisiae)0.016
hist2h3ca1histone 2, H3ca10.016
itga2bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)0.016
efna2ephrin A20.016
slc30a7solute carrier family 30 (zinc transporter), member 70.016
LOC555504novel protocadherin protein0.015
slc30a2solute carrier family 30 (zinc transporter), member 20.015
pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.015
lrig1leucine-rich repeats and immunoglobulin-like domains 10.015
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.015
bmpr1babone morphogenetic protein receptor, type 1ba0.014
efcab7EF-hand calcium binding domain 70.014
mpv17MpV17 transgene, murine homolog, glomerulosclerosis0.014
olig4oligodendrocyte transcription factor 40.014
map3k4mitogen activated protein kinase kinase kinase 40.014
rplp1ribosomal protein, large, P10.014
si:ch211-150a22.1si:ch211-150a22.10.013
si:dkeyp-69b9.5si:dkeyp-69b9.50.013
nup88nucleoporin 880.013
zgc:136925zgc:1369250.013
haus3HAUS augmin-like complex, subunit 30.013
cutl1cut-like 1 (Drosophila)0.013
zgc:64119zgc:641190.013
pdcd4bprogrammed cell death 4b0.013
senp6aSUMO1/sentrin specific peptidase 6a0.013
srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.012
mosv-mos Moloney murine sarcoma viral oncogene homolog0.012
bnc2basonuclin 20.012
med24mediator complex subunit 240.012
exosc8exosome component 80.012
zgc:112254zgc:1122540.012
rspo1R-spondin homolog (Xenopus laevis)0.012
hspb12heat shock protein, alpha-crystallin-related, b120.012
tubgcp3tubulin, gamma complex associated protein 30.012
si:dkey-109n11.1si:dkey-109n11.10.012
zgc:113518zgc:1135180.012
hsf2heat shock factor 20.012
adh5alcohol dehydrogenase 50.011
zgc:110137zgc:1101370.011
nr2e3nuclear receptor subfamily 2, group E, member 30.011
zfhx3zinc finger homeobox 30.011
rradRas-related associated with diabetes0.011
wdr24WD repeat domain 240.011
LOC572344hypothetical protein LOC5723440.011
cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
spn-Espindle E0.489
piwiCG6122 gene product from transcript CG6122-RA0.375
okrokra0.034
CG4771CG4771 gene product from transcript CG4771-RA0.031
CG5524CG5524 gene product from transcript CG5524-RA0.023
lokloki0.017
Brca2Breast cancer 2, early onset homolog0.016
Smc5CG32438 gene product from transcript CG32438-RE0.016
bambag of marbles0.013
armiarmitage0.013
stwlstonewall0.012
orboo18 RNA-binding protein0.012
swaswallow0.011
Nup160Nucleoporin 1600.010
zpgzero population growth0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MSH6mutS homolog 6 (E. coli)0.856
PMS2PMS2 postmeiotic segregation increased 2 (S. cerevisiae)0.665
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.388
EXO1exonuclease 10.113
ZNF830zinc finger protein 8300.088
THOC5THO complex 50.058
BRIP1BRCA1 interacting protein C-terminal helicase 10.055
MSH3mutS homolog 3 (E. coli)0.042
PNKPpolynucleotide kinase 3'-phosphatase0.035
CLSPNclaspin0.027
RAD1RAD1 homolog (S. pombe)0.027
RPA1replication protein A1, 70kDa0.024
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.022
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.019
CHEK1CHK1 checkpoint homolog (S. pombe)0.018
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.018
DTLdenticleless homolog (Drosophila)0.016
PMS1PMS1 postmeiotic segregation increased 1 (S. cerevisiae)0.016
SLX4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)0.013
NCOR2nuclear receptor corepressor 20.013
PCDH9protocadherin 90.013
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.011
NCAPGnon-SMC condensin I complex, subunit G0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RAD52Rad52p0.020
IRC8Irc8p0.015
RAD1Rad1p0.013
MSH3Msh3p0.013
SNT1Snt1p0.011
SRS2Srs2p0.011
RTF1Rtf1p0.011
RFA1Rfa1p0.011