The network for 'low density lipoprotein particle remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

low density lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.

NameDescriptionProbabilityFunc Analog Organism
Apoa1apolipoprotein A-I0.967
Apoeapolipoprotein E0.543
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.458
Apobapolipoprotein B0.379
Hnf4ahepatic nuclear factor 4, alpha0.058
Aldobaldolase B, fructose-bisphosphate0.058
Lyz2lysozyme 20.055
F2coagulation factor II0.040
Apoc3apolipoprotein C-III0.039
Fgbfibrinogen beta chain0.038
Apoa2apolipoprotein A-II0.035
Serpinc1serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 10.034
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.032
Npc1Niemann Pick type C10.031
Cyp2c70cytochrome P450, family 2, subfamily c, polypeptide 700.031
Gcgrglucagon receptor0.027
Ahsgalpha-2-HS-glycoprotein0.026
Dmgdhdimethylglycine dehydrogenase precursor0.026
Plgplasminogen0.025
Nos3nitric oxide synthase 3, endothelial cell0.023
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.023
Fggfibrinogen gamma chain0.022
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.022
Gcgroup specific component0.020
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.020
Ambpalpha 1 microglobulin/bikunin0.019
Apomapolipoprotein M0.019
F10coagulation factor X0.018
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.017
F12coagulation factor XII (Hageman factor)0.015
Mt1metallothionein 10.015
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.014
Abcg8ATP-binding cassette, sub-family G (WHITE), member 80.013
Ldlrlow density lipoprotein receptor0.013
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.013
Pltpphospholipid transfer protein0.013
Kcnj9potassium inwardly-rectifying channel, subfamily J, member 90.012
Lrp1low density lipoprotein receptor-related protein 10.012
Ppargperoxisome proliferator activated receptor gamma0.012
Cdhr5cadherin-related family member 50.012
Apoa5apolipoprotein A-V0.012
Azgp1alpha-2-glycoprotein 1, zinc0.011
Atp13a2ATPase type 13A20.011
Rxraretinoid X receptor alpha0.011
C9complement component 90.011
Apoc4apolipoprotein C-IV0.011
Prnpprion protein0.011
Scd1stearoyl-Coenzyme A desaturase 10.011
Cyp46a1cytochrome P450, family 46, subfamily a, polypeptide 10.010
Pipoxpipecolic acid oxidase0.010
Cdk5r2cyclin-dependent kinase 5, regulatory subunit 2 (p39)0.010
Asgr2asialoglycoprotein receptor 20.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
A2Malpha-2-macroglobulin0.663
HPhaptoglobin0.120
APOC1apolipoprotein C-I0.080
ALBalbumin0.078
APOA1apolipoprotein A-I0.071
APOC2apolipoprotein C-II0.027
RPL18Aribosomal protein L18a0.016
MDKmidkine (neurite growth-promoting factor 2)0.015
APOBapolipoprotein B (including Ag(x) antigen)0.012
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism