IMP
Process View
The network for 'regulation of dna damage checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of dna damage checkpoint
Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 1.000 | |
| Per2 | period homolog 2 (Drosophila) | 1.000 | |
| Clock | circadian locomotor output cycles kaput | 1.000 | |
| Per1 | period homolog 1 (Drosophila) | 0.916 | |
| Sirt1 | sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) | 0.377 | |
| Csnk1e | casein kinase 1, epsilon | 0.230 | |
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.107 | |
| Trim28 | tripartite motif-containing 28 | 0.096 | |
| Ewsr1 | Ewing sarcoma breakpoint region 1 | 0.096 | |
| Mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.091 | |
| Trrap | transformation/transcription domain-associated protein | 0.083 | |
| Cdk9 | cyclin-dependent kinase 9 (CDC2-related kinase) | 0.080 | |
| Usp2 | ubiquitin specific peptidase 2 | 0.071 | |
| Crebbp | CREB binding protein | 0.062 | |
| Brd2 | bromodomain containing 2 | 0.055 | |
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.051 | |
| Gm12372 | predicted gene 12372 | 0.050 | |
| Ssrp1 | structure specific recognition protein 1 | 0.047 | |
| Srsf4 | serine/arginine-rich splicing factor 4 | 0.037 | |
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.037 | |
| Pcid2 | PCI domain containing 2 | 0.033 | |
| Pum1 | pumilio 1 (Drosophila) | 0.032 | |
| Mitf | microphthalmia-associated transcription factor | 0.032 | |
| U2af1 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 | 0.032 | |
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.029 | |
| Anapc5 | anaphase-promoting complex subunit 5 | 0.029 | |
| Cdk4 | cyclin-dependent kinase 4 | 0.029 | |
| Rfc3 | replication factor C (activator 1) 3 | 0.028 | |
| Cdkn2aipnl | CDKN2A interacting protein N-terminal like | 0.028 | |
| Ofd1 | oral-facial-digital syndrome 1 gene homolog (human) | 0.028 | |
| Refbp2 | RNA and export factor binding protein 2 | 0.027 | |
| Lrrc40 | leucine rich repeat containing 40 | 0.027 | |
| Cks1b | CDC28 protein kinase 1b | 0.027 | |
| Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.026 | |
| H2afy | H2A histone family, member Y | 0.026 | |
| Impdh2 | inosine 5'-phosphate dehydrogenase 2 | 0.026 | |
| Thoc4 | THO complex 4 | 0.026 | |
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 0.025 | |
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.024 | |
| Reps1 | RalBP1 associated Eps domain containing protein | 0.023 | |
| Cwc27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | 0.023 | |
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.022 | |
| Zfp317 | zinc finger protein 317 | 0.021 | |
| Edc4 | enhancer of mRNA decapping 4 | 0.021 | |
| Srsf9 | serine/arginine-rich splicing factor 9 | 0.021 | |
| Rfc2 | replication factor C (activator 1) 2 | 0.020 | |
| Npas2 | neuronal PAS domain protein 2 | 0.020 | |
| Ankrd28 | ankyrin repeat domain 28 | 0.020 | |
| Rnf8 | ring finger protein 8 | 0.019 | |
| Gmnn | geminin | 0.018 | |
| Phf16 | PHD finger protein 16 | 0.018 | |
| Pabpn1 | poly(A) binding protein, nuclear 1 | 0.018 | |
| Dcaf15 | DDB1 and CUL4 associated factor 15 | 0.018 | |
| Srrm2 | serine/arginine repetitive matrix 2 | 0.018 | |
| Rpa1 | replication protein A1 | 0.018 | |
| Tubgcp2 | tubulin, gamma complex associated protein 2 | 0.018 | |
| Dmap1 | DNA methyltransferase 1-associated protein 1 | 0.017 | |
| Safb2 | scaffold attachment factor B2 | 0.017 | |
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.017 | |
| Puf60 | poly-U binding splicing factor 60 | 0.017 | |
| Atr | ataxia telangiectasia and Rad3 related | 0.017 | |
| Hdac3 | histone deacetylase 3 | 0.017 | |
| Fam192a | family with sequence similarity 192, member A | 0.016 | |
| Qser1 | glutamine and serine rich 1 | 0.015 | |
| Prkca | protein kinase C, alpha | 0.015 | |
| Fubp3 | far upstream element (FUSE) binding protein 3 | 0.015 | |
| Cry1 | cryptochrome 1 (photolyase-like) | 0.015 | |
| Rpl3 | ribosomal protein L3 | 0.015 | |
| Mib1 | mindbomb homolog 1 (Drosophila) | 0.015 | |
| Parp2 | poly (ADP-ribose) polymerase family, member 2 | 0.015 | |
| Fastkd2 | FAST kinase domains 2 | 0.015 | |
| Tstd2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | 0.015 | |
| Prpf6 | PRP6 pre-mRNA splicing factor 6 homolog (yeast) | 0.015 | |
| Rcc2 | regulator of chromosome condensation 2 | 0.015 | |
| Hmgb3 | high mobility group box 3 | 0.015 | |
| Mta2 | metastasis-associated gene family, member 2 | 0.014 | |
| Grsf1 | G-rich RNA sequence binding factor 1 | 0.014 | |
| Vps16 | vacuolar protein sorting 16 (yeast) | 0.014 | |
| Prpf3 | PRP3 pre-mRNA processing factor 3 homolog (yeast) | 0.014 | |
| Lsm2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.014 | |
| Ncapg2 | non-SMC condensin II complex, subunit G2 | 0.014 | |
| Mum1 | melanoma associated antigen (mutated) 1 | 0.014 | |
| Hdac1 | histone deacetylase 1 | 0.014 | |
| Zc3hc1 | zinc finger, C3HC type 1 | 0.014 | |
| Irs2 | insulin receptor substrate 2 | 0.014 | |
| Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.014 | |
| Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.014 | |
| Dmxl1 | Dmx-like 1 | 0.014 | |
| Tle3 | transducin-like enhancer of split 3, homolog of Drosophila E(spl) | 0.014 | |
| Xab2 | XPA binding protein 2 | 0.014 | |
| Safb | scaffold attachment factor B | 0.014 | |
| Klhl2 | kelch-like 2, Mayven (Drosophila) | 0.014 | |
| Dbr1 | debranching enzyme homolog 1 (S. cerevisiae) | 0.014 | |
| Csnk1d | casein kinase 1, delta | 0.013 | |
| Dnajc9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.013 | |
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.013 | |
| Xpo6 | exportin 6 | 0.013 | |
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.013 | |
| Snrpb | small nuclear ribonucleoprotein B | 0.013 | |
| Smad1 | MAD homolog 1 (Drosophila) | 0.013 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.997 | |
| THOC4 | THO complex 4 | 0.930 | |
| THOC1 | THO complex 1 | 0.859 | |
| THOC5 | THO complex 5 | 0.525 | |
| THOC2 | THO complex 2 | 0.226 | |
| RPA1 | replication protein A1, 70kDa | 0.110 | |
| CHTOP | chromatin target of PRMT1 | 0.027 | |
| CUL2 | cullin 2 | 0.027 | |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.026 | |
| STRN4 | striatin, calmodulin binding protein 4 | 0.025 | |
| THOC6 | THO complex 6 homolog (Drosophila) | 0.021 | |
| CCNT1 | cyclin T1 | 0.020 | |
| RFWD2 | ring finger and WD repeat domain 2 | 0.018 | |
| THOC7 | THO complex 7 homolog (Drosophila) | 0.015 | |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | 0.014 | |
| JMJD6 | jumonji domain containing 6 | 0.014 | |
| CUL1 | cullin 1 | 0.014 | |
| TUBA1B | tubulin, alpha 1b | 0.014 | |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.010 | |
| FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | 0.010 | |
| ZNF830 | zinc finger protein 830 | 0.010 |