The network for 'regulation of dna damage checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dna damage checkpoint

Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.

NameDescriptionProbabilityFunc Analog Organism
Arntlaryl hydrocarbon receptor nuclear translocator-like1.000
Per2period homolog 2 (Drosophila)1.000
Clockcircadian locomotor output cycles kaput1.000
Per1period homolog 1 (Drosophila)0.916
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.377
Csnk1ecasein kinase 1, epsilon0.230
Arid1aAT rich interactive domain 1A (SWI-like)0.107
Trim28tripartite motif-containing 280.096
Ewsr1Ewing sarcoma breakpoint region 10.096
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.091
Trraptransformation/transcription domain-associated protein0.083
Cdk9cyclin-dependent kinase 9 (CDC2-related kinase)0.080
Usp2ubiquitin specific peptidase 20.071
CrebbpCREB binding protein0.062
Brd2bromodomain containing 20.055
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.051
Gm12372predicted gene 123720.050
Ssrp1structure specific recognition protein 10.047
Srsf4serine/arginine-rich splicing factor 40.037
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.037
Pcid2PCI domain containing 20.033
Pum1pumilio 1 (Drosophila)0.032
Mitfmicrophthalmia-associated transcription factor0.032
U2af1U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 10.032
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.029
Anapc5anaphase-promoting complex subunit 50.029
Cdk4cyclin-dependent kinase 40.029
Rfc3replication factor C (activator 1) 30.028
Cdkn2aipnlCDKN2A interacting protein N-terminal like0.028
Ofd1oral-facial-digital syndrome 1 gene homolog (human)0.028
Refbp2RNA and export factor binding protein 20.027
Lrrc40leucine rich repeat containing 400.027
Cks1bCDC28 protein kinase 1b0.027
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.026
H2afyH2A histone family, member Y0.026
Impdh2inosine 5'-phosphate dehydrogenase 20.026
Thoc4THO complex 40.026
Eif2c2eukaryotic translation initiation factor 2C, 20.025
Asxl1additional sex combs like 1 (Drosophila)0.024
Reps1RalBP1 associated Eps domain containing protein0.023
Cwc27CWC27 spliceosome-associated protein homolog (S. cerevisiae)0.023
Chd4chromodomain helicase DNA binding protein 40.022
Zfp317zinc finger protein 3170.021
Edc4enhancer of mRNA decapping 40.021
Srsf9serine/arginine-rich splicing factor 90.021
Rfc2replication factor C (activator 1) 20.020
Npas2neuronal PAS domain protein 20.020
Ankrd28ankyrin repeat domain 280.020
Rnf8ring finger protein 80.019
Gmnngeminin0.018
Phf16PHD finger protein 160.018
Pabpn1poly(A) binding protein, nuclear 10.018
Dcaf15DDB1 and CUL4 associated factor 150.018
Srrm2serine/arginine repetitive matrix 20.018
Rpa1replication protein A10.018
Tubgcp2tubulin, gamma complex associated protein 20.018
Dmap1DNA methyltransferase 1-associated protein 10.017
Safb2scaffold attachment factor B20.017
Arpc4actin related protein 2/3 complex, subunit 40.017
Puf60poly-U binding splicing factor 600.017
Atrataxia telangiectasia and Rad3 related0.017
Hdac3histone deacetylase 30.017
Fam192afamily with sequence similarity 192, member A0.016
Qser1glutamine and serine rich 10.015
Prkcaprotein kinase C, alpha0.015
Fubp3far upstream element (FUSE) binding protein 30.015
Cry1cryptochrome 1 (photolyase-like)0.015
Rpl3ribosomal protein L30.015
Mib1mindbomb homolog 1 (Drosophila)0.015
Parp2poly (ADP-ribose) polymerase family, member 20.015
Fastkd2FAST kinase domains 20.015
Tstd2thiosulfate sulfurtransferase (rhodanese)-like domain containing 20.015
Prpf6PRP6 pre-mRNA splicing factor 6 homolog (yeast)0.015
Rcc2regulator of chromosome condensation 20.015
Hmgb3high mobility group box 30.015
Mta2metastasis-associated gene family, member 20.014
Grsf1G-rich RNA sequence binding factor 10.014
Vps16vacuolar protein sorting 16 (yeast)0.014
Prpf3PRP3 pre-mRNA processing factor 3 homolog (yeast)0.014
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.014
Ncapg2non-SMC condensin II complex, subunit G20.014
Mum1melanoma associated antigen (mutated) 10.014
Hdac1histone deacetylase 10.014
Zc3hc1zinc finger, C3HC type 10.014
Irs2insulin receptor substrate 20.014
Srrtserrate RNA effector molecule homolog (Arabidopsis)0.014
Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 30.014
Dmxl1Dmx-like 10.014
Tle3transducin-like enhancer of split 3, homolog of Drosophila E(spl)0.014
Xab2XPA binding protein 20.014
Safbscaffold attachment factor B0.014
Klhl2kelch-like 2, Mayven (Drosophila)0.014
Dbr1debranching enzyme homolog 1 (S. cerevisiae)0.014
Csnk1dcasein kinase 1, delta0.013
Dnajc9DnaJ (Hsp40) homolog, subfamily C, member 90.013
Dnmt1DNA methyltransferase (cytosine-5) 10.013
Xpo6exportin 60.013
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.013
Snrpbsmall nuclear ribonucleoprotein B0.013
Smad1MAD homolog 1 (Drosophila)0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.997
THOC4THO complex 40.930
THOC1THO complex 10.859
THOC5THO complex 50.525
THOC2THO complex 20.226
RPA1replication protein A1, 70kDa0.110
CHTOPchromatin target of PRMT10.027
CUL2cullin 20.027
DDB1damage-specific DNA binding protein 1, 127kDa0.026
STRN4striatin, calmodulin binding protein 40.025
THOC6THO complex 6 homolog (Drosophila)0.021
CCNT1cyclin T10.020
RFWD2ring finger and WD repeat domain 20.018
THOC7THO complex 7 homolog (Drosophila)0.015
PPM1Fprotein phosphatase, Mg2+/Mn2+ dependent, 1F0.014
JMJD6jumonji domain containing 60.014
CUL1cullin 10.014
TUBA1Btubulin, alpha 1b0.014
PPP4R2protein phosphatase 4, regulatory subunit 20.010
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.010
ZNF830zinc finger protein 8300.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism