The network for 'sorbitol biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sorbitol biosynthetic process

The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Mgst2microsomal glutathione S-transferase 20.267
Tuba1ctubulin, alpha 1C0.249
Psmb5proteasome (prosome, macropain) subunit, beta type 50.207
Pgam1phosphoglycerate mutase 1 (brain)0.154
Oaz1ornithine decarboxylase antizyme 10.136
Rplp2ribosomal protein, large P20.126
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.118
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.101
Dapk3death-associated protein kinase 30.076
Rpn1ribophorin I0.076
Ppargperoxisome proliferator-activated receptor gamma0.067
Aldh6a1aldehyde dehydrogenase 6 family, member A10.061
Slc35b1solute carrier family 35, member B10.057
Anxa2annexin A20.056
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.049
Akr1c12aldo-keto reductase family 1, member C120.046
Mosc1MOCO sulphurase C-terminal domain containing 10.046
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.042
Adh1alcohol dehydrogenase 1 (class I)0.036
Mup5major urinary protein 50.035
Fabp12fatty acid binding protein 120.034
Anks4bankyrin repeat and sterile alpha motif domain containing 4B0.031
Slc17a1solute carrier family 17 (sodium phosphate), member 10.030
Prdx2peroxiredoxin 20.029
Nat1N-acetyltransferase 10.029
Pdzk1PDZ domain containing 10.029
Slco1b3solute carrier organic anion transporter family, member 1b30.028
Rnf207ring finger protein 2070.027
Ghrgrowth hormone receptor0.027
Acmsdaminocarboxymuconate semialdehyde decarboxylase0.026
Ephx1epoxide hydrolase 1, microsomal0.025
Slc17a3solute carrier family 17 (sodium phosphate), member 30.023
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.023
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.022
As3mtarsenic (+3 oxidation state) methyltransferase0.022
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.022
LOC688473similar to 40S ribosomal protein S20.021
G6pdglucose-6-phosphate dehydrogenase0.021
Fmo2flavin containing monooxygenase 20.021
Il15interleukin 150.021
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.020
Gsta5glutathione S-transferase Yc2 subunit0.019
Hint3histidine triad nucleotide binding protein 30.019
Akr1c19aldo-keto reductase family 1, member C190.019
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.019
Akr1c14aldo-keto reductase family 1, member C140.019
Acsm2acyl-CoA synthetase medium-chain family member 20.018
Cyp2c7cytochrome P450, family 2, subfamily c, polypeptide 70.018
Dpm2dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit0.018
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.018
Cd36CD36 molecule (thrombospondin receptor)0.018
Ftlferritin, light polypeptide0.017
Nat8N-acetyltransferase 80.017
Tas2r105taste receptor, type 2, member 1050.017
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.016
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.016
Lratlecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)0.016
Cyp2j4cytochrome P450, family 2, subfamily j, polypeptide 40.016
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.015
Slc40a1solute carrier family 39 (iron-regulated transporter), member 10.015
Bphlbiphenyl hydrolase-like (serine hydrolase)0.015
Sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.014
Cyb5acytochrome b5 type A (microsomal)0.014
Tmem66transmembrane protein 660.014
Prl7a4prolactin family 7, subfamily a, member 40.014
Gpx4glutathione peroxidase 40.014
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.013
Bbox1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 10.013
LOC100360843ribosomal protein S19-like0.013
Pbldphenazine biosynthesis-like protein domain containing0.013
Otcornithine carbamoyltransferase0.013
Shroom1shroom family member 10.012
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.012
UST4rintegral membrane transport protein UST4r0.012
Calm1calmodulin 10.012
Ces1ccarboxylesterase 1C0.012
Pex11aperoxisomal biogenesis factor 11 alpha0.012
Aadacarylacetamide deacetylase (esterase)0.012
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.012
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.011
Mrpl16mitochondrial ribosomal protein L160.011
Akr1cl1aldo-keto reductase family 1, member C-like 10.011
Kif16bkinesin family member 16B0.010
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.010
Otud1OTU domain containing 10.010
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.010
Hmox1heme oxygenase (decycling) 10.010
Rbp7retinol binding protein 7, cellular0.010
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism