The network for 'spindle assembly involved in meiosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spindle assembly involved in meiosis

The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.

NameDescriptionProbabilityFunc Analog Organism
Cdc25ccell division cycle 25 homolog C (S. pombe)0.991
Cdk1cyclin-dependent kinase 10.966
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.956
Ccnb1cyclin B10.916
Birc5baculoviral IAP repeat-containing 50.839
Prc1protein regulator of cytokinesis 10.829
Kif20akinesin family member 20A0.772
Ccnb2cyclin B20.743
Ccna2cyclin A20.733
Kif22kinesin family member 220.638
Kif23kinesin family member 230.634
Trim59tripartite motif-containing 590.551
Racgap1Rac GTPase-activating protein 10.504
Cdca8cell division cycle associated 80.487
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.431
Ckap2cytoskeleton associated protein 20.394
H2afxH2A histone family, member X0.370
Fam64afamily with sequence similarity 64, member A0.362
Tacc3transforming, acidic coiled-coil containing protein 30.342
Kif11kinesin family member 110.331
Aurkbaurora kinase B0.322
Ccnfcyclin F0.307
Smc4structural maintenance of chromosomes 40.304
Smc2structural maintenance of chromosomes 20.294
Top2atopoisomerase (DNA) II alpha0.268
Kif2ckinesin family member 2C0.224
Cdca5cell division cycle associated 50.222
Capza1capping protein (actin filament) muscle Z-line, alpha 10.220
Dlgap5discs, large (Drosophila) homolog-associated protein 50.206
Plk1polo-like kinase 1 (Drosophila)0.196
Kif4kinesin family member 40.176
Anlnanillin, actin binding protein0.157
Cdc25bcell division cycle 25 homolog B (S. pombe)0.156
Hmgb2high mobility group box 20.155
Ube2cubiquitin-conjugating enzyme E2C0.137
Mxd3Max dimerization protein 30.131
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.127
Ncaphnon-SMC condensin I complex, subunit H0.127
Aurkaaurora kinase A0.123
Mis18bp1MIS18 binding protein 10.120
Cenpacentromere protein A0.119
Gtse1G two S phase expressed protein 10.117
Spag5sperm associated antigen 50.116
Hmmrhyaluronan mediated motility receptor (RHAMM)0.114
Gsg2germ cell-specific gene 20.112
TtkTtk protein kinase0.112
Cdca2cell division cycle associated 20.110
Plk4polo-like kinase 4 (Drosophila)0.110
C330027C09RikRIKEN cDNA C330027C09 gene0.108
Mki67antigen identified by monoclonal antibody Ki 670.100
Incenpinner centromere protein0.092
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.082
Rrm2ribonucleotide reductase M20.080
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.078
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.075
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.068
Trip13thyroid hormone receptor interactor 130.068
H2afzH2A histone family, member Z0.067
Lmnb1lamin B10.067
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.066
Ckap2lcytoskeleton associated protein 2-like0.061
Ect2ect2 oncogene0.060
Ncapd2non-SMC condensin I complex, subunit D20.058
Ube2tubiquitin-conjugating enzyme E2T (putative)0.057
Adam10a disintegrin and metallopeptidase domain 100.055
Rasa1RAS p21 protein activator 10.055
Cenpkcentromere protein K0.054
Fcho1FCH domain only 10.053
Cks2CDC28 protein kinase regulatory subunit 20.048
Dtldenticleless homolog (Drosophila)0.047
Ccdc99coiled-coil domain containing 990.046
Kpna2karyopherin (importin) alpha 20.044
E2f8E2F transcription factor 80.042
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.040
Pola1polymerase (DNA directed), alpha 10.038
Top2btopoisomerase (DNA) II beta0.038
Chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)0.037
Cdc25acell division cycle 25 homolog A (S. pombe)0.036
Lims1LIM and senescent cell antigen-like domains 10.036
Pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.035
Fam83dfamily with sequence similarity 83, member D0.034
Ncapgnon-SMC condensin I complex, subunit G0.033
Mastlmicrotubule associated serine/threonine kinase-like0.033
Tcf19transcription factor 190.032
Hnrpllheterogeneous nuclear ribonucleoprotein L-like0.032
Maptmicrotubule-associated protein tau0.032
Cenpfcentromere protein F0.031
Foxm1forkhead box M10.031
Cdkn3cyclin-dependent kinase inhibitor 30.031
Iqgap3IQ motif containing GTPase activating protein 30.030
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.029
Stag1stromal antigen 10.029
Casc5cancer susceptibility candidate 50.029
Cenpncentromere protein N0.029
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.029
Ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.028
Sh3bgrlSH3-binding domain glutamic acid-rich protein like0.028
StilScl/Tal1 interrupting locus0.027
Rpa3replication protein A30.027
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ccnb1cyclin B10.968
aurkbaurora kinase B0.789
sass6spindle assembly 6 homolog (C. elegans)0.700
pou5f1POU domain, class 5, transcription factor 10.535
btg2B-cell translocation gene 20.531
plk1polo-like kinase 1 (Drosophila)0.431
kif23kinesin family member 230.390
aurkaaurora kinase A0.253
ccna2cyclin A20.233
gmnngeminin, DNA replication inhibitor0.202
top2atopoisomerase (DNA) II alpha0.184
vasavasa homolog0.147
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.123
lrmplymphoid-restricted membrane protein0.110
ccnb2cyclin B20.108
ccnecyclin E0.107
smad5MAD homolog 5 (Drosophila)0.105
eomesaeomesodermin homolog a0.095
tp53tumor protein p530.085
dusp1dual specificity phosphatase 10.080
unguracil-DNA glycosylase0.076
dhfrdihydrofolate reductase0.061
chaf1bchromatin assembly factor 1, subunit B0.060
LOC100000332e3 ubiquitin-protein ligase RNF182-like0.055
ndr1nodal-related 10.052
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.051
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.050
mpped2metallophosphoesterase domain containing 20.049
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.046
krt18keratin 180.044
bucbucky ball0.040
nedd1neural precursor cell expressed, developmentally down-regulated 10.039
ncapd2non-SMC condensin I complex, subunit D20.038
limk2LIM domain kinase 20.038
hn1lhematological and neurological expressed 1-like0.037
scube2signal peptide, CUB domain, EGF-like 20.036
stilTAL1 (SCL) interrupting locus0.036
sox19bSRY-box containing gene 19b0.035
hspa5heat shock protein 50.034
gng5guanine nucleotide binding protein (G protein), gamma 50.034
pmaip1phorbol-12-myristate-13-acetate-induced protein 10.033
ncapgnon-SMC condensin I complex, subunit G0.032
gins3GINS complex subunit 30.032
nusap1nucleolar and spindle associated protein 10.031
suv39h1bsuppressor of variegation 3-9 homolog 1b0.031
dtldenticleless homolog (Drosophila)0.031
dnmt1DNA (cytosine-5-)-methyltransferase 10.031
prrc1proline-rich coiled-coil 10.030
polr2apolymerase (RNA) II (DNA directed) polypeptide A0.029
prkciprotein kinase C, iota0.028
dnddead end0.028
sarsseryl-tRNA synthetase0.027
LOC797832similar to signal peptide, CUB domain, EGF-like 10.027
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.027
cdc20cell division cycle 20 homolog0.027
ints6integrator complex subunit 60.027
smc4structural maintenance of chromosomes 40.025
krit1KRIT1, ankyrin repeat containing0.025
hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.025
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.024
mychmyelocytomatosis oncogene homolog0.024
odc1ornithine decarboxylase 10.024
mosv-mos Moloney murine sarcoma viral oncogene homolog0.024
sybusyntabulin (syntaxin-interacting)0.024
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.024
plk4polo-like kinase 4 (Drosophila)0.023
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.023
maxmyc-associated factor X0.022
ca15bcarbonic anhydrase XV b0.022
glulbglutamate-ammonia ligase (glutamine synthase) b0.021
sox11bSRY-box containing gene 11b0.021
e2f5E2F transcription factor 50.021
eef2beukaryotic translation elongation factor 2b0.020
cdc25cell division cycle 25 homolog0.020
m6prmannose-6-phosphate receptor (cation dependent)0.019
pppde1PPPDE peptidase domain containing 10.019
znf711zinc finger protein 7110.019
LOC554173abnormal spindles0.019
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.019
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.018
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.018
cbsbcystathionine-beta-synthase b0.018
csrnp1acysteine-serine-rich nuclear protein 1a0.018
pglyrp2peptidoglycan recognition protein 20.018
rtkn2rhotekin 20.018
slc25a22solute carrier family 25 (mitochondrial carrier: glutamate), member 220.017
LOC557270eukaryotic translation initiation factor 3, subunit F-like0.017
htra1aHtrA serine peptidase 1a0.017
ppp1cblprotein phosphatase 1, catalytic subunit, beta isoform, like0.016
msh6mutS homolog 6 (E. coli)0.016
narno arches0.016
arl6ip1ADP-ribosylation factor-like 6 interacting protein 10.016
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ncdnon-claret disjunctional1.000
poloCG12306 gene product from transcript CG12306-RA0.995
BubR1Bub1-related kinase0.973
gammaTub37Cgamma-Tubulin at 37C0.946
Klp10ACG1453 gene product from transcript CG1453-RA0.914
Cks30ACyclin-dependent kinase subunit 30A0.889
marsCG17064 gene product from transcript CG17064-RB0.816
Grip71CG10346 gene product from transcript CG10346-RA0.794
Klp61FKinesin-like protein at 61F0.747
Klp3AKinesin-like protein at 3A0.659
spd-2spindle defective 20.273
Spc25CG7242 gene product from transcript CG7242-RA0.262
larpLa related protein0.252
Syx13Syntaxin 130.248
Klp67AKinesin-like protein at 67A0.240
CycBCyclin B0.211
msd1mitotic spindle density 10.177
Grip163CG5688 gene product from transcript CG5688-RA0.151
mei-S332meiotic from via Salaria 3320.144
CG4680CG4680 gene product from transcript CG4680-RA0.126
Sgt1CG9617 gene product from transcript CG9617-RA0.125
Cenp-CCG31258 gene product from transcript CG31258-RA0.097
mit(1)15mitotic 150.094
aspabnormal spindle0.085
dpadisc proliferation abnormal0.083
AxsAbnormal X segregation0.083
nodno distributive disjunction0.075
Nek2CG17256 gene product from transcript CG17256-RA0.074
Fs(2)KetFemale sterile (2) Ketel0.058
gammaTub23Cgamma-Tubulin at 23C0.052
ana3anastral spindle 30.052
MybMyb oncogene-like0.038
piepineapple eye0.036
Mis12CG18156 gene product from transcript CG18156-RA0.035
Grip128CG9201 gene product from transcript CG9201-RB0.035
Cdc37CG12019 gene product from transcript CG12019-RA0.034
c(3)Gcrossover suppressor on 3 of Gowen0.034
CycB3Cyclin B30.032
O-fut1O-fucosyltransferase 10.027
ordorientation disruptor0.024
rodrough deal0.022
Orc5Origin recognition complex subunit 50.022
tacctransforming acidic coiled-coil protein0.022
Psf2CG18013 gene product from transcript CG18013-RA0.021
betaTub56Dbeta-Tubulin at 56D0.021
mei-217CG33935 gene product from transcript CG33935-RC0.020
wacwee Augmin0.020
ranCG1404 gene product from transcript CG1404-RB0.019
CycECyclin E0.018
CG6719CG6719 gene product from transcript CG6719-RA0.017
pngpan gu0.017
spn-Espindle E0.017
sanseparation anxiety0.017
Grip75CG6176 gene product from transcript CG6176-RA0.016
ana2anastral spindle 20.016
CG8605CG8605 gene product from transcript CG8605-RA0.015
Orc2Origin recognition complex subunit 20.015
PsiP-element somatic inhibitor0.015
pex1peroxin 10.015
Tap42Two A-associated protein of 42kDa0.014
mei-218meiotic 2180.014
spn-Aspindle A0.014
alphaTub67Calpha-Tubulin at 67C0.013
nopono poles0.013
rtettetracycline resistance0.012
pex13peroxin 130.012
lkb1CG9374 gene product from transcript CG9374-RJ0.012
Cap-H2Chromosome associated protein H20.012
fwdfour wheel drive0.012
Cdc27CG8610 gene product from transcript CG8610-RA0.011
Grip84gamma-tubulin ring protein 840.011
CycACyclin A0.011
c(2)Mcrossover suppressor on 2 of Manheim0.011
pds5CG17509 gene product from transcript CG17509-RA0.010
Cep135CG17081 gene product from transcript CG17081-RB0.010
InvadolysinCG3953 gene product from transcript CG3953-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism