The network for 'pole plasm assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pole plasm assembly

Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.

NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 11.000
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide1.000
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)1.000
Apcadenomatosis polyposis coli0.999
Stx1asyntaxin 1A (brain)0.999
Dlg4discs, large homolog 4 (Drosophila)0.995
Gsk3bglycogen synthase kinase 3 beta0.992
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.990
Snap25synaptosomal-associated protein 250.979
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.976
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.958
Hif1ahypoxia inducible factor 1, alpha subunit0.953
Fusfusion, derived from t(12;16) malignant liposarcoma (human)0.937
Hspa8heat shock protein 80.936
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.926
Vamp2vesicle-associated membrane protein 20.926
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.920
Smad4MAD homolog 4 (Drosophila)0.919
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.899
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.874
Htthuntingtin0.865
Inainternexin neuronal intermediate filament protein, alpha0.778
Bmpr1abone morphogenetic protein receptor, type 1A0.761
Ptenphosphatase and tensin homolog0.756
Mapre1microtubule-associated protein, RP/EB family, member 10.747
Ccnd1cyclin D10.740
Tsc1tuberous sclerosis 10.709
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.693
Cdkn1bcyclin-dependent kinase inhibitor 1B0.676
Dlg2discs, large homolog 2 (Drosophila)0.670
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.668
Nedd4neural precursor cell expressed, developmentally down-regulated 40.668
Stx12syntaxin 120.668
Cltcclathrin, heavy polypeptide (Hc)0.667
Dlg1discs, large homolog 1 (Drosophila)0.637
Nf1neurofibromatosis 10.629
Mtap2microtubule-associated protein 20.618
Bicd2bicaudal D homolog 2 (Drosophila)0.612
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.596
Psen1presenilin 10.590
Rb1retinoblastoma 10.575
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.570
SetSET nuclear oncogene0.568
Spnb2spectrin beta 20.562
Ccdc64coiled-coil domain containing 640.558
Itgb1integrin beta 1 (fibronectin receptor beta)0.555
Prmt5protein arginine N-methyltransferase 50.543
Cct6achaperonin containing Tcp1, subunit 6a (zeta)0.541
Prkceprotein kinase C, epsilon0.537
Smad1MAD homolog 1 (Drosophila)0.516
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.507
Eif5aeukaryotic translation initiation factor 5A0.507
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.498
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.486
Thbs1thrombospondin 10.456
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform0.453
Nrcamneuron-glia-CAM-related cell adhesion molecule0.435
Kif5akinesin family member 5A0.434
Maelmaelstrom homolog (Drosophila)0.408
Pum1pumilio 1 (Drosophila)0.405
Kdm1alysine (K)-specific demethylase 1A0.400
BrafBraf transforming gene0.394
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.379
Mdm2transformed mouse 3T3 cell double minute 20.376
Cct2chaperonin containing Tcp1, subunit 2 (beta)0.373
Dlgap1discs, large (Drosophila) homolog-associated protein 10.373
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.369
Cdkn2acyclin-dependent kinase inhibitor 2A0.355
Ptges3prostaglandin E synthase 3 (cytosolic)0.348
Arcactivity regulated cytoskeletal-associated protein0.343
Sult4a1sulfotransferase family 4A, member 10.343
SrcRous sarcoma oncogene0.340
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.340
Nudcnuclear distribution gene C homolog (Aspergillus)0.332
Dnm1dynamin 10.329
Rpgrip1lRpgrip1-like0.328
Ddx3xDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked0.326
Bsnbassoon0.307
Vcpvalosin containing protein0.306
2500003M10RikRIKEN cDNA 2500003M10 gene0.303
Trp53transformation related protein 530.297
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.295
Eif4heukaryotic translation initiation factor 4H0.295
Clstn1calsyntenin 10.289
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.284
Srsf2serine/arginine-rich splicing factor 20.280
Snrpd1small nuclear ribonucleoprotein D10.279
Stxbp1syntaxin binding protein 10.277
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.271
Appamyloid beta (A4) precursor protein0.265
Tsc2tuberous sclerosis 20.265
Cdk4cyclin-dependent kinase 40.260
Snrpbsmall nuclear ribonucleoprotein B0.260
Aplp2amyloid beta (A4) precursor-like protein 20.258
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.258
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.253
Ewsr1Ewing sarcoma breakpoint region 10.252
Msh2mutS homolog 2 (E. coli)0.252
Tbcatubulin cofactor A0.249
Kif5ckinesin family member 5C0.246
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
par-5Protein PAR-50.893
glh-1Protein GLH-10.646
Y65B4BR.5Protein Y65B4BR.50.635
tba-2Protein TBA-20.582
snr-4Protein SNR-40.487
pas-3Protein PAS-30.404
mcm-2Protein MCM-20.369
pgl-1Protein PGL-10.366
rars-1Protein RARS-10.356
lbp-9Protein LBP-90.355
par-2Protein PAR-20.347
ucr-2.3Protein UCR-2.30.332
glh-4Protein GLH-40.310
tbb-2Protein TBB-20.304
snr-3Protein SNR-30.286
CELE_C01G10.8Protein C01G10.80.254
R07E5.7Protein R07E5.70.235
klp-15Protein KLP-150.234
prg-2Protein PRG-20.222
ina-1Protein INA-10.205
prg-1Protein PRG-10.203
CELE_C17H12.13Protein C17H12.130.198
rpl-11.1Protein RPL-11.10.198
rpl-25.2Protein RPL-25.20.196
icd-1Protein ICD-10.193
R12C12.6Protein R12C12.60.187
pbs-4Protein PBS-40.184
rpl-7Protein RPL-70.183
tbb-1Protein TBB-10.179
imb-3Protein IMB-30.175
K06A5.1Protein K06A5.10.167
xpo-2Protein XPO-20.165
ife-1Protein IFE-10.163
eef-1A.1Protein EEF-1A.10.162
hsp-1Protein HSP-10.157
arx-7Protein ARX-70.156
rpt-3Protein RPT-30.155
wago-4Protein WAGO-40.142
rpl-6Protein RPL-60.139
rec-8Protein REC-80.138
cbd-1Protein CBD-10.138
cgh-1Protein CGH-10.136
rpa-2Protein RPA-20.120
CELE_Y57G11C.3Protein Y57G11C.30.116
CELE_Y54E10BR.5Protein Y54E10BR.50.116
T28D9.1Protein T28D9.10.115
npl-4.2Protein NPL-4.20.112
pbs-6Protein PBS-60.103
goa-1Protein GOA-10.096
K07H8.3Protein K07H8.30.096
CELE_C18C4.5Protein C18C4.50.094
chc-1Protein CHC-10.094
CELE_Y14H12B.2Protein Y14H12B.20.092
gba-3Protein GBA-30.092
zif-1Protein ZIF-10.089
csnk-1Protein CSNK-10.089
rpl-12Protein RPL-120.088
btf-1Protein BTF-10.086
pas-4Protein PAS-40.086
K07C5.3Protein K07C5.30.084
rpl-3Protein RPL-30.083
rps-2Protein RPS-20.082
rpl-4Protein RPL-40.080
rpt-5Protein RPT-50.079
rpl-2Protein RPL-20.079
rps-6Protein RPS-60.076
snr-2Protein SNR-20.075
W08E12.7Protein W08E12.70.074
unc-116Protein UNC-1160.074
rpl-15Protein RPL-150.074
rpl-13Protein RPL-130.072
pab-1Protein PAB-10.071
rpb-8Protein RPB-80.070
dnj-5Protein DNJ-50.070
spk-1Protein SPK-10.067
CELE_Y14H12B.1Protein Y14H12B.10.067
pas-2Protein PAS-20.067
gpb-1Protein GPB-10.067
rho-1Protein RHO-10.066
mog-2Protein MOG-20.066
mac-1Protein MAC-10.064
R186.7Protein R186.70.064
hlh-30Protein HLH-300.061
iff-1Protein IFF-10.061
mcm-4Protein MCM-40.061
cst-2Protein CST-20.060
usp-14Protein USP-140.059
csr-1Protein CSR-10.059
CELE_Y18D10A.11Protein Y18D10A.110.059
CELE_C16C10.4Protein C16C10.40.059
cct-1Protein CCT-10.059
F31C3.3Protein F31C3.30.058
wago-1Protein WAGO-10.058
F56D2.6Protein F56D2.60.057
rack-1Protein RACK-10.057
rla-0Protein RLA-00.057
pqn-87Protein PQN-870.056
perm-1Protein PERM-10.055
klc-2Protein KLC-20.055
F10G8.8Protein F10G8.80.054
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 31.000
piwil1piwi-like 1 (Drosophila)0.999
piwil2piwi-like 2 (Drosophila)0.975
dazldaz-like gene0.954
zgc:103482zgc:1034820.686
dlg2discs, large (Drosophila) homolog 20.657
ilf2interleukin enhancer binding factor 20.642
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.630
orgoogenesis-related gene0.621
elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.607
ef1aelongation factor 1-alpha0.557
dnddead end0.539
ca15bcarbonic anhydrase XV b0.517
brca2breast cancer 2, early onset0.512
fanclFanconi anemia, complementation group L0.400
rnf17ring finger protein 170.336
vasavasa homolog0.328
eef1geukaryotic translation elongation factor 1 gamma0.320
snx6sorting nexin 60.302
zorbaOrb/CPEB-related RNA-binding protein0.297
cltcbclathrin, heavy polypeptide b (Hc)0.287
elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.271
eif4a1aeukaryotic translation initiation factor 4A, isoform 1A0.268
ube2naubiquitin-conjugating enzyme E2Na0.261
spsb1splA/ryanodine receptor domain and SOCS box containing 10.255
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.242
hk1hexokinase 10.239
tdrd1tudor domain containing 10.238
znf711zinc finger protein 7110.236
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.233
bucbucky ball0.229
rpl3ribosomal protein L30.226
rpl4ribosomal protein L40.220
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.218
eif5aeukaryotic translation initiation factor 5A0.214
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.213
sfrs3bsplicing factor, arginine/serine-rich 3b0.210
snrpd3lsmall nuclear ribonucleoprotein D3 polypeptide, like0.206
ck2bcasein kinase 2 beta0.205
zgc:193933zgc:1939330.203
smu1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.201
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.201
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.201
tdrd7tudor domain containing 70.198
asz1ankyrin repeat, SAM and basic leucine zipper domain containing 10.197
hnrnpa0heterogeneous nuclear ribonucleoprotein A00.196
tpm4tropomyosin 40.196
rps4xribosomal protein S4, X-linked0.193
rpl23aribosomal protein L23a0.192
si:ch1073-351m12.1si:ch1073-351m12.10.189
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.181
zgc:77366zgc:773660.174
cntn1acontactin 1a0.171
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.167
nclnucleolin0.162
pobpartial optokinetic response b0.161
tpt1tumor protein, translationally-controlled 10.160
pfn2profilin 20.157
gdf9growth differentiation factor 90.153
flot1bflotillin 1b0.150
actr10actin-related protein 10 homolog (S. cerevisiae)0.147
magohmago-nashi homolog, proliferation-associated (Drosophila)0.146
psen1presenilin 10.143
mpzmyelin protein zero0.142
tubg1tubulin, gamma 10.138
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.138
usp5ubiquitin specific protease 50.135
bactin1bactin10.132
zgc:56005zgc:560050.132
cct7chaperonin containing TCP1, subunit 7 (eta)0.131
LOC561889granulito0.130
dynlt3dynein, light chain, Tctex-type 30.130
pak2ap21 (CDKN1A)-activated kinase 2a0.128
g3bp1GTPase activating protein (SH3 domain) binding protein 10.125
sf1splicing factor 10.125
henmt1HEN1 methyltransferase homolog 1 (Arabidopsis)0.124
si:ch211-67f24.5si:ch211-67f24.50.123
grcc10gene rich cluster, C10 gene0.123
zgc:112425zgc:1124250.122
rpl5bribosomal protein L5b0.122
stk25bserine/threonine kinase 25b0.122
arf2ADP-ribosylation factor 20.121
prkd1protein kinase D10.121
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.119
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.117
acvr1bactivin A receptor, type IB0.116
rspo1R-spondin homolog (Xenopus laevis)0.116
esyt3extended synaptotagmin-like protein 30.115
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.114
api5apoptosis inhibitor 50.113
hnrnpuheterogeneous nuclear ribonucleoprotein U0.111
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.111
hspa8heat shock protein 80.109
ewsr1bEwing sarcoma breakpoint region 1b0.107
srisorcin0.106
il13ra2interleukin 13 receptor, alpha 20.106
hnrnpl2heterogeneous nuclear ribonucleoprotein L20.104
celf1cugbp, Elav-like family member 10.104
rap1bRAS related protein 1b0.103
sybusyntabulin (syntaxin-interacting)0.103
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
BicDBicaudal D1.000
par-1CG8201 gene product from transcript CG8201-RA1.000
sqdsquid1.000
aPKCatypical protein kinase C0.999
bazbazooka0.999
KhcKinesin heavy chain0.999
TER94CG2331 gene product from transcript CG2331-RA0.997
Cdc42CG12530 gene product from transcript CG12530-RA0.997
oskoskar0.991
LamLamin0.991
DlicDynein light intermediate chain0.991
Dhc64CDynein heavy chain 64C0.991
sec5CG8843 gene product from transcript CG8843-RA0.990
vasvasa0.985
gloglorund0.981
Src64BSrc oncogene at 64B0.973
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.972
Hel25EHelicase at 25E0.971
tsutsunagi0.971
staustaufen0.970
SRPKCG8174 gene product from transcript CG8174-RA0.964
vlsvalois0.963
magomago nashi0.955
par-6CG5884 gene product from transcript CG5884-RA0.952
CG11188CG11188 gene product from transcript CG11188-RA0.944
CG6854CG6854 gene product from transcript CG6854-RC0.942
maelmaelstrom0.927
rokRho-kinase0.906
ecdecdysoneless0.899
tudtudor0.897
tho2CG31671 gene product from transcript CG31671-RA0.895
piwiCG6122 gene product from transcript CG6122-RA0.892
aretarrest0.891
Dcp1Decapping protein 10.888
sqhspaghetti squash0.878
Atx2Ataxin-20.867
Sop2Suppressor of profilin 20.840
spn-Espindle E0.825
eghegghead0.818
me31Bmaternal expression at 31B0.794
Nup154Nucleoporin 1540.793
slmbsupernumerary limbs0.785
CG10260CG10260 gene product from transcript CG10260-RB0.766
bratbrain tumor0.761
pitaCG3941 gene product from transcript CG3941-RA0.742
Tm1Tropomyosin 10.735
shgshotgun0.714
bcdbicoid0.688
Pi3K21BCG2699 gene product from transcript CG2699-RA0.643
spirspire0.631
cpacapping protein alpha0.612
Eip75BEcdysone-induced protein 75B0.599
alpha-Specalpha Spectrin0.592
Lis-1Lissencephaly-10.566
belbelle0.556
traltrailer hitch0.536
aubaubergine0.527
eggeggless0.510
RpL10AbRibosomal protein L10Ab0.500
htshu li tai shao0.495
krimpkrimper0.490
orboo18 RNA-binding protein0.461
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.457
mtrmmatrimony0.456
pumpumilio0.448
CG17838CG17838 gene product from transcript CG17838-RA0.444
saxsaxophone0.443
mxcmulti sex combs0.435
Mi-2CG8103 gene product from transcript CG8103-RA0.407
nosnanos0.400
Pabp2CG2163 gene product from transcript CG2163-RA0.395
CG4771CG4771 gene product from transcript CG4771-RA0.394
ChcClathrin heavy chain0.394
csulcapsuleen0.381
hbhunchback0.357
psqpipsqueak0.345
mirrmirror0.344
grkgurken0.336
liclicorne0.327
ensensconsin0.315
Ets97DEts at 97D0.309
exuexuperantia0.307
crbcrumbs0.293
dcodiscs overgrown0.272
ttktramtrack0.236
Btk29ABtk family kinase at 29A0.231
qmquemao0.221
RopRas opposite0.221
deldeadlock0.219
spn-FCG12114 gene product from transcript CG12114-RA0.215
dapdacapo0.211
lwrlesswright0.209
jagnjagunal0.209
lsnlarsen0.200
smt3CG4494 gene product from transcript CG4494-RA0.193
Rab5Rab-protein 50.179
HtrA2CG8464 gene product from transcript CG8464-RA0.175
Fmr1CG6203 gene product from transcript CG6203-RC0.172
CG4415CG4415 gene product from transcript CG4415-RA0.169
CG4420CG4420 gene product from transcript CG4420-RA0.169
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism