IMP
Process View
The network for 'histone h4 k16 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
histone h4 k16 acetylation
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.953 | |
| Rbbp5 | retinoblastoma binding protein 5 | 0.934 | |
| Atg12 | autophagy-related 12 (yeast) | 0.906 | |
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.750 | |
| Kat2a | K(lysine) acetyltransferase 2A | 0.658 | |
| Ash2l | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.584 | |
| Trp53 | transformation related protein 53 | 0.581 | |
| Rnf44 | ring finger protein 44 | 0.352 | |
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.349 | |
| Atm | ataxia telangiectasia mutated homolog (human) | 0.340 | |
| Rere | arginine glutamic acid dipeptide (RE) repeats | 0.327 | |
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.311 | |
| Hcfc1 | host cell factor C1 | 0.299 | |
| Brca2 | breast cancer 2 | 0.292 | |
| Phf12 | PHD finger protein 12 | 0.246 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.245 | |
| Nolc1 | nucleolar and coiled-body phosphoprotein 1 | 0.224 | |
| Crebbp | CREB binding protein | 0.214 | |
| Trrap | transformation/transcription domain-associated protein | 0.210 | |
| Atg3 | autophagy-related 3 (yeast) | 0.161 | |
| Ubqln4 | ubiquilin 4 | 0.152 | |
| Ddx17 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 0.150 | |
| Wbp7 | WW domain binding protein 7 | 0.148 | |
| Clk1 | CDC-like kinase 1 | 0.144 | |
| D4Wsu53e | DNA segment, Chr 4, Wayne State University 53, expressed | 0.138 | |
| Macf1 | microtubule-actin crosslinking factor 1 | 0.136 | |
| Ubp1 | upstream binding protein 1 | 0.125 | |
| Atr | ataxia telangiectasia and Rad3 related | 0.122 | |
| Tnrc6c | trinucleotide repeat containing 6C | 0.119 | |
| Nbn | nibrin | 0.119 | |
| Zkscan3 | zinc finger with KRAB and SCAN domains 3 | 0.117 | |
| Fbxl3 | F-box and leucine-rich repeat protein 3 | 0.116 | |
| Pten | phosphatase and tensin homolog | 0.115 | |
| Nfya | nuclear transcription factor-Y alpha | 0.106 | |
| Acin1 | apoptotic chromatin condensation inducer 1 | 0.098 | |
| Ylpm1 | YLP motif containing 1 | 0.089 | |
| L3mbtl2 | l(3)mbt-like 2 (Drosophila) | 0.089 | |
| Med13l | mediator complex subunit 13-like | 0.086 | |
| Clk4 | CDC like kinase 4 | 0.076 | |
| Msl1 | male-specific lethal 1 homolog (Drosophila) | 0.071 | |
| Atg10 | autophagy-related 10 (yeast) | 0.064 | |
| Spen | SPEN homolog, transcriptional regulator (Drosophila) | 0.062 | |
| Dip2b | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.061 | |
| Tshz1 | teashirt zinc finger family member 1 | 0.059 | |
| Zfp740 | zinc finger protein 740 | 0.058 | |
| Tada2a | transcriptional adaptor 2A | 0.058 | |
| Usp48 | ubiquitin specific peptidase 48 | 0.056 | |
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.055 | |
| Mgea5 | meningioma expressed antigen 5 (hyaluronidase) | 0.055 | |
| Nf2 | neurofibromatosis 2 | 0.053 | |
| Cnot6l | CCR4-NOT transcription complex, subunit 6-like | 0.052 | |
| ND6 | NADH dehydrogenase subunit 6 | 0.051 | |
| Crebzf | CREB/ATF bZIP transcription factor | 0.051 | |
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.050 | |
| Clk2 | CDC-like kinase 2 | 0.049 | |
| Casc3 | cancer susceptibility candidate 3 | 0.048 | |
| Atxn7l3 | ataxin 7-like 3 | 0.047 | |
| Sf1 | splicing factor 1 | 0.047 | |
| Rnf111 | ring finger 111 | 0.047 | |
| Akap8l | A kinase (PRKA) anchor protein 8-like | 0.046 | |
| Smarcc2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.044 | |
| Gpatch8 | G patch domain containing 8 | 0.043 | |
| Camsap1 | calmodulin regulated spectrin-associated protein 1 | 0.043 | |
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.042 | |
| Cad | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.042 | |
| AW549877 | expressed sequence AW549877 | 0.041 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.041 | |
| Rbl2 | retinoblastoma-like 2 | 0.040 | |
| Rad51 | RAD51 homolog (S. cerevisiae) | 0.040 | |
| Fam193b | family with sequence similarity 193, member B | 0.039 | |
| D730040F13Rik | RIKEN cDNA D730040F13 gene | 0.039 | |
| Ep300 | E1A binding protein p300 | 0.039 | |
| Xpo5 | exportin 5 | 0.037 | |
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.036 | |
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.036 | |
| Csrp2bp | cysteine and glycine-rich protein 2 binding protein | 0.035 | |
| Dgcr2 | DiGeorge syndrome critical region gene 2 | 0.035 | |
| Ncor1 | nuclear receptor co-repressor 1 | 0.034 | |
| Zmynd11 | zinc finger, MYND domain containing 11 | 0.034 | |
| Men1 | multiple endocrine neoplasia 1 | 0.034 | |
| Ep400 | E1A binding protein p400 | 0.033 | |
| Ccnl2 | cyclin L2 | 0.033 | |
| Exosc10 | exosome component 10 | 0.032 | |
| Rmnd5a | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.032 | |
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.032 | |
| Npepps | aminopeptidase puromycin sensitive | 0.032 | |
| Smg7 | Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) | 0.031 | |
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.031 | |
| Anapc1 | anaphase promoting complex subunit 1 | 0.031 | |
| Pbx2 | pre B-cell leukemia transcription factor 2 | 0.031 | |
| Ifrd2 | interferon-related developmental regulator 2 | 0.029 | |
| Safb2 | scaffold attachment factor B2 | 0.029 | |
| Foxk2 | forkhead box K2 | 0.029 | |
| 2610027L16Rik | RIKEN cDNA 2610027L16 gene | 0.029 | |
| Zfc3h1 | zinc finger, C3H1-type containing | 0.028 | |
| Usp21 | ubiquitin specific peptidase 21 | 0.028 | |
| Setdb1 | SET domain, bifurcated 1 | 0.028 | |
| Mapk14 | mitogen-activated protein kinase 14 | 0.027 | |
| Dhx8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.027 | |
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.026 |
Loading network...
Drosophila melanogaster| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| msl-1 | male-specific lethal 1 | 0.981 | |
| mof | males absent on the first | 0.961 | |
| msl-2 | male-specific lethal 2 | 0.894 | |
| Hcf | Host cell factor | 0.775 | |
| msl-3 | male-specific lethal 3 | 0.542 | |
| Sir2 | CG5216 gene product from transcript CG5216-RA | 0.205 | |
| Chd1 | Chromodomain-helicase-DNA-binding protein 1 | 0.157 | |
| CG3363 | CG3363 gene product from transcript CG3363-RB | 0.122 | |
| dik | diskette | 0.119 | |
| brm | brahma | 0.114 | |
| Su(var)3-3 | Suppressor of variegation 3-3 | 0.112 | |
| Nipped-A | CG33554 gene product from transcript CG33554-RE | 0.112 | |
| ash1 | absent, small, or homeotic discs 1 | 0.107 | |
| Caf1 | Chromatin assembly factor 1 subunit | 0.090 | |
| CG9772 | CG9772 gene product from transcript CG9772-RB | 0.077 | |
| Atg6 | Autophagy-specific gene 6 | 0.069 | |
| krz | kurtz | 0.061 | |
| Tip60 | CG6121 gene product from transcript CG6121-RA | 0.051 | |
| EloA | Elongin A | 0.045 | |
| Scm | Sex comb on midleg | 0.044 | |
| g | garnet | 0.044 | |
| fs(1)h | female sterile (1) homeotic | 0.042 | |
| mle | maleless | 0.040 | |
| pr-set7 | CG3307 gene product from transcript CG3307-RC | 0.038 | |
| Sxl | Sex lethal | 0.037 | |
| her | hermaphrodite | 0.035 | |
| BRWD3 | CG31132 gene product from transcript CG31132-RA | 0.034 | |
| bon | bonus | 0.034 | |
| egg | eggless | 0.033 | |
| vir | virilizer | 0.032 | |
| Tao-1 | CG14217 gene product from transcript CG14217-RF | 0.027 | |
| ph-d | polyhomeotic distal | 0.026 | |
| CG14614 | CG14614 gene product from transcript CG14614-RA | 0.026 | |
| Rga | Regena | 0.023 | |
| CG5385 | CG5385 gene product from transcript CG5385-RA | 0.022 | |
| Pcaf | CG4107 gene product from transcript CG4107-RA | 0.022 | |
| Gmd | GDP-mannose 4,6-dehydratase | 0.021 | |
| Su(z)2 | Suppressor of zeste 2 | 0.021 | |
| CG11093 | CG11093 gene product from transcript CG11093-RB | 0.020 | |
| defl | deflated | 0.020 | |
| Snr1 | Snf5-related 1 | 0.019 | |
| Mocs2 | Molybdopterin synthase 2 | 0.019 | |
| sxc | super sex combs | 0.018 | |
| Dok | Downstream of kinase | 0.017 | |
| CTCF | CG8591 gene product from transcript CG8591-RA | 0.016 | |
| Su(z)12 | CG8013 gene product from transcript CG8013-RA | 0.016 | |
| sisA | sisterless A | 0.015 | |
| CG32711 | CG32711 gene product from transcript CG32711-RA | 0.015 | |
| hipk | homeodomain interacting protein kinase | 0.015 | |
| CG16908 | CG16908 gene product from transcript CG16908-RA | 0.014 | |
| Stam | Signal transducing adaptor molecule | 0.014 | |
| CG8090 | CG8090 gene product from transcript CG8090-RB | 0.014 | |
| CG9795 | CG9795 gene product from transcript CG9795-RD | 0.014 | |
| Atg9 | Autophagy-specific gene 9 | 0.014 | |
| Lk6 | CG17342 gene product from transcript CG17342-RA | 0.014 | |
| Atg7 | Autophagy-specific gene 7 | 0.013 | |
| tan | tantalus | 0.013 | |
| wapl | wings apart-like | 0.013 | |
| Pez | CG9493 gene product from transcript CG9493-RA | 0.013 | |
| CG10107 | CG10107 gene product from transcript CG10107-RA | 0.013 | |
| Tango6 | Transport and Golgi organization 6 | 0.013 | |
| ebi | CG4063 gene product from transcript CG4063-RA | 0.012 | |
| ksr | kinase suppressor of ras | 0.012 | |
| wda | will decrease acetylation | 0.012 | |
| ytr | yantar | 0.011 | |
| CG4699 | CG4699 gene product from transcript CG4699-RJ | 0.011 | |
| lid | little imaginal discs | 0.011 | |
| Vps4 | Vacuolar protein sorting 4 | 0.011 | |
| CG5591 | CG5591 gene product from transcript CG5591-RA | 0.011 | |
| CG4495 | CG4495 gene product from transcript CG4495-RA | 0.011 | |
| Atg18 | Autophagy-specific gene 18 | 0.011 | |
| B52 | CG10851 gene product from transcript CG10851-RB | 0.011 | |
| Krn | Keren | 0.011 | |
| Clic | Chloride intracellular channel | 0.010 | |
| key | kenny | 0.010 | |
| Su(var)3-7 | Suppressor of variegation 3-7 | 0.010 | |
| Bap170 | Brahma associated protein 170kD | 0.010 | |
| Pi4KIIalpha | CG2929 gene product from transcript CG2929-RC | 0.010 | |
| noi | noisette | 0.010 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.984 | |
| WDR5 | WD repeat domain 5 | 0.983 | |
| MYST3 | MYST histone acetyltransferase (monocytic leukemia) 3 | 0.606 | |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.486 | |
| MEN1 | multiple endocrine neoplasia I | 0.453 | |
| RBBP5 | retinoblastoma binding protein 5 | 0.342 | |
| MRFAP1 | Morf4 family associated protein 1 | 0.314 | |
| HIST1H3B | histone cluster 1, H3b | 0.247 | |
| MYST1 | MYST histone acetyltransferase 1 | 0.147 | |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.114 | |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) | 0.102 | |
| ATG3 | ATG3 autophagy related 3 homolog (S. cerevisiae) | 0.086 | |
| NBN | nibrin | 0.076 | |
| HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.074 | |
| MRFAP1L1 | Morf4 family associated protein 1-like 1 | 0.071 | |
| MORF4L2 | mortality factor 4 like 2 | 0.066 | |
| ATG12 | ATG12 autophagy related 12 homolog (S. cerevisiae) | 0.053 | |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) | 0.049 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.042 | |
| NINL | ninein-like | 0.040 | |
| INO80E | INO80 complex subunit E | 0.036 | |
| CXXC1 | CXXC finger protein 1 | 0.035 | |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.032 | |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.031 | |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.030 | |
| ZBTB17 | zinc finger and BTB domain containing 17 | 0.029 | |
| AFF1 | AF4/FMR2 family, member 1 | 0.028 | |
| AFF4 | AF4/FMR2 family, member 4 | 0.027 | |
| C20orf20 | chromosome 20 open reading frame 20 | 0.025 | |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.025 | |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.024 | |
| CREBBP | CREB binding protein | 0.024 | |
| ATG16L1 | ATG16 autophagy related 16-like 1 (S. cerevisiae) | 0.023 | |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 0.019 | |
| KIAA1377 | KIAA1377 | 0.019 | |
| MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.018 | |
| CDK11B | cyclin-dependent kinase 11B | 0.018 | |
| CCNT1 | cyclin T1 | 0.018 | |
| KAT5 | K(lysine) acetyltransferase 5 | 0.017 | |
| ATG7 | ATG7 autophagy related 7 homolog (S. cerevisiae) | 0.017 | |
| AR | androgen receptor | 0.016 | |
| SETD1A | SET domain containing 1A | 0.016 | |
| TP53 | tumor protein p53 | 0.016 | |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.016 | |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.015 | |
| PEX12 | peroxisomal biogenesis factor 12 | 0.015 | |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.015 | |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.013 | |
| SNAPIN | SNAP-associated protein | 0.013 | |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 0.013 | |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) | 0.013 | |
| CREBZF | CREB/ATF bZIP transcription factor | 0.013 | |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.012 | |
| THAP11 | THAP domain containing 11 | 0.012 | |
| ATM | ataxia telangiectasia mutated | 0.012 | |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.011 | |
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 0.010 | |
| RBM23 | RNA binding motif protein 23 | 0.010 |