The network for 'histone h4 k16 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h4 k16 acetylation

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.

NameDescriptionProbabilityFunc Analog Organism
Arid1aAT rich interactive domain 1A (SWI-like)0.953
Rbbp5retinoblastoma binding protein 50.934
Atg12autophagy-related 12 (yeast)0.906
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.750
Kat2aK(lysine) acetyltransferase 2A0.658
Ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.584
Trp53transformation related protein 530.581
Rnf44ring finger protein 440.352
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.349
Atmataxia telangiectasia mutated homolog (human)0.340
Rerearginine glutamic acid dipeptide (RE) repeats0.327
Sin3atranscriptional regulator, SIN3A (yeast)0.311
Hcfc1host cell factor C10.299
Brca2breast cancer 20.292
Phf12PHD finger protein 120.246
Mdm2transformed mouse 3T3 cell double minute 20.245
Nolc1nucleolar and coiled-body phosphoprotein 10.224
CrebbpCREB binding protein0.214
Trraptransformation/transcription domain-associated protein0.210
Atg3autophagy-related 3 (yeast)0.161
Ubqln4ubiquilin 40.152
Ddx17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.150
Wbp7WW domain binding protein 70.148
Clk1CDC-like kinase 10.144
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.138
Macf1microtubule-actin crosslinking factor 10.136
Ubp1upstream binding protein 10.125
Atrataxia telangiectasia and Rad3 related0.122
Tnrc6ctrinucleotide repeat containing 6C0.119
Zkscan3zinc finger with KRAB and SCAN domains 30.117
Fbxl3F-box and leucine-rich repeat protein 30.116
Ptenphosphatase and tensin homolog0.115
Nfyanuclear transcription factor-Y alpha0.106
Acin1apoptotic chromatin condensation inducer 10.098
Ylpm1YLP motif containing 10.089
L3mbtl2l(3)mbt-like 2 (Drosophila)0.089
Med13lmediator complex subunit 13-like0.086
Clk4CDC like kinase 40.076
Msl1male-specific lethal 1 homolog (Drosophila)0.071
Atg10autophagy-related 10 (yeast)0.064
SpenSPEN homolog, transcriptional regulator (Drosophila)0.062
Dip2bDIP2 disco-interacting protein 2 homolog B (Drosophila)0.061
Tshz1teashirt zinc finger family member 10.059
Zfp740zinc finger protein 7400.058
Tada2atranscriptional adaptor 2A0.058
Usp48ubiquitin specific peptidase 480.056
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.055
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.055
Nf2neurofibromatosis 20.053
Cnot6lCCR4-NOT transcription complex, subunit 6-like0.052
ND6NADH dehydrogenase subunit 60.051
CrebzfCREB/ATF bZIP transcription factor0.051
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.050
Clk2CDC-like kinase 20.049
Casc3cancer susceptibility candidate 30.048
Atxn7l3ataxin 7-like 30.047
Sf1splicing factor 10.047
Rnf111ring finger 1110.047
Akap8lA kinase (PRKA) anchor protein 8-like0.046
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.044
Gpatch8G patch domain containing 80.043
Camsap1calmodulin regulated spectrin-associated protein 10.043
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.042
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.042
AW549877expressed sequence AW5498770.041
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.041
Rbl2retinoblastoma-like 20.040
Rad51RAD51 homolog (S. cerevisiae)0.040
Fam193bfamily with sequence similarity 193, member B0.039
D730040F13RikRIKEN cDNA D730040F13 gene0.039
Ep300E1A binding protein p3000.039
Xpo5exportin 50.037
Asxl1additional sex combs like 1 (Drosophila)0.036
Huwe1HECT, UBA and WWE domain containing 10.036
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.035
Dgcr2DiGeorge syndrome critical region gene 20.035
Ncor1nuclear receptor co-repressor 10.034
Zmynd11zinc finger, MYND domain containing 110.034
Men1multiple endocrine neoplasia 10.034
Ep400E1A binding protein p4000.033
Ccnl2cyclin L20.033
Exosc10exosome component 100.032
Rmnd5arequired for meiotic nuclear division 5 homolog A (S. cerevisiae)0.032
Cdc7cell division cycle 7 (S. cerevisiae)0.032
Npeppsaminopeptidase puromycin sensitive0.032
Smg7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)0.031
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.031
Anapc1anaphase promoting complex subunit 10.031
Pbx2pre B-cell leukemia transcription factor 20.031
Ifrd2interferon-related developmental regulator 20.029
Safb2scaffold attachment factor B20.029
Foxk2forkhead box K20.029
2610027L16RikRIKEN cDNA 2610027L16 gene0.029
Zfc3h1zinc finger, C3H1-type containing0.028
Usp21ubiquitin specific peptidase 210.028
Setdb1SET domain, bifurcated 10.028
Mapk14mitogen-activated protein kinase 140.027
Dhx8DEAH (Asp-Glu-Ala-His) box polypeptide 80.027
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
msl-1male-specific lethal 10.981
mofmales absent on the first0.961
msl-2male-specific lethal 20.894
HcfHost cell factor0.775
msl-3male-specific lethal 30.542
Sir2CG5216 gene product from transcript CG5216-RA0.205
Chd1Chromodomain-helicase-DNA-binding protein 10.157
CG3363CG3363 gene product from transcript CG3363-RB0.122
Su(var)3-3Suppressor of variegation 3-30.112
Nipped-ACG33554 gene product from transcript CG33554-RE0.112
ash1absent, small, or homeotic discs 10.107
Caf1Chromatin assembly factor 1 subunit0.090
CG9772CG9772 gene product from transcript CG9772-RB0.077
Atg6Autophagy-specific gene 60.069
Tip60CG6121 gene product from transcript CG6121-RA0.051
EloAElongin A0.045
ScmSex comb on midleg0.044
fs(1)hfemale sterile (1) homeotic0.042
pr-set7CG3307 gene product from transcript CG3307-RC0.038
SxlSex lethal0.037
BRWD3CG31132 gene product from transcript CG31132-RA0.034
Tao-1CG14217 gene product from transcript CG14217-RF0.027
ph-dpolyhomeotic distal0.026
CG14614CG14614 gene product from transcript CG14614-RA0.026
CG5385CG5385 gene product from transcript CG5385-RA0.022
PcafCG4107 gene product from transcript CG4107-RA0.022
GmdGDP-mannose 4,6-dehydratase0.021
Su(z)2Suppressor of zeste 20.021
CG11093CG11093 gene product from transcript CG11093-RB0.020
Snr1Snf5-related 10.019
Mocs2Molybdopterin synthase 20.019
sxcsuper sex combs0.018
DokDownstream of kinase0.017
CTCFCG8591 gene product from transcript CG8591-RA0.016
Su(z)12CG8013 gene product from transcript CG8013-RA0.016
sisAsisterless A0.015
CG32711CG32711 gene product from transcript CG32711-RA0.015
hipkhomeodomain interacting protein kinase0.015
CG16908CG16908 gene product from transcript CG16908-RA0.014
StamSignal transducing adaptor molecule0.014
CG8090CG8090 gene product from transcript CG8090-RB0.014
CG9795CG9795 gene product from transcript CG9795-RD0.014
Atg9Autophagy-specific gene 90.014
Lk6CG17342 gene product from transcript CG17342-RA0.014
Atg7Autophagy-specific gene 70.013
waplwings apart-like0.013
PezCG9493 gene product from transcript CG9493-RA0.013
CG10107CG10107 gene product from transcript CG10107-RA0.013
Tango6Transport and Golgi organization 60.013
ebiCG4063 gene product from transcript CG4063-RA0.012
ksrkinase suppressor of ras0.012
wdawill decrease acetylation0.012
CG4699CG4699 gene product from transcript CG4699-RJ0.011
lidlittle imaginal discs0.011
Vps4Vacuolar protein sorting 40.011
CG5591CG5591 gene product from transcript CG5591-RA0.011
CG4495CG4495 gene product from transcript CG4495-RA0.011
Atg18Autophagy-specific gene 180.011
B52CG10851 gene product from transcript CG10851-RB0.011
ClicChloride intracellular channel0.010
Su(var)3-7Suppressor of variegation 3-70.010
Bap170Brahma associated protein 170kD0.010
Pi4KIIalphaCG2929 gene product from transcript CG2929-RC0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.984
WDR5WD repeat domain 50.983
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.606
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.486
MEN1multiple endocrine neoplasia I0.453
RBBP5retinoblastoma binding protein 50.342
MRFAP1Morf4 family associated protein 10.314
HIST1H3Bhistone cluster 1, H3b0.247
MYST1MYST histone acetyltransferase 10.147
MBIPMAP3K12 binding inhibitory protein 10.114
MGEA5meningioma expressed antigen 5 (hyaluronidase)0.102
ATG3ATG3 autophagy related 3 homolog (S. cerevisiae)0.086
HCFC1host cell factor C1 (VP16-accessory protein)0.074
MRFAP1L1Morf4 family associated protein 1-like 10.071
MORF4L2mortality factor 4 like 20.066
ATG12ATG12 autophagy related 12 homolog (S. cerevisiae)0.053
BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)0.049
SIN3ASIN3 homolog A, transcription regulator (yeast)0.042
INO80EINO80 complex subunit E0.036
CXXC1CXXC finger protein 10.035
VPS72vacuolar protein sorting 72 homolog (S. cerevisiae)0.032
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.031
CALCOCO2calcium binding and coiled-coil domain 20.030
ZBTB17zinc finger and BTB domain containing 170.029
AFF1AF4/FMR2 family, member 10.028
AFF4AF4/FMR2 family, member 40.027
C20orf20chromosome 20 open reading frame 200.025
CSNK2A2casein kinase 2, alpha prime polypeptide0.025
PHC2polyhomeotic homolog 2 (Drosophila)0.024
CREBBPCREB binding protein0.024
ATG16L1ATG16 autophagy related 16-like 1 (S. cerevisiae)0.023
PPIEpeptidylprolyl isomerase E (cyclophilin E)0.019
MLL2myeloid/lymphoid or mixed-lineage leukemia 20.018
CDK11Bcyclin-dependent kinase 11B0.018
CCNT1cyclin T10.018
KAT5K(lysine) acetyltransferase 50.017
ATG7ATG7 autophagy related 7 homolog (S. cerevisiae)0.017
ARandrogen receptor0.016
SETD1ASET domain containing 1A0.016
TP53tumor protein p530.016
PLEKHA5pleckstrin homology domain containing, family A member 50.016
CHD8chromodomain helicase DNA binding protein 80.015
PEX12peroxisomal biogenesis factor 120.015
WDFY3WD repeat and FYVE domain containing 30.015
EPC2enhancer of polycomb homolog 2 (Drosophila)0.013
SNAPINSNAP-associated protein0.013
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.013
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.013
CREBZFCREB/ATF bZIP transcription factor0.013
UHRF2ubiquitin-like with PHD and ring finger domains 20.012
THAP11THAP domain containing 110.012
ATMataxia telangiectasia mutated0.012
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.011
DMAP1DNA methyltransferase 1 associated protein 10.010
RBM23RNA binding motif protein 230.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism