The network for 'oocyte anterior posterior axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

oocyte anterior posterior axis specification

Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.

NameDescriptionProbabilityFunc Analog Organism
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide1.000
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.999
Ctnnb1catenin (cadherin associated protein), beta 10.997
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.965
Stx1asyntaxin 1A (brain)0.964
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.952
Snap25synaptosomal-associated protein 250.935
Apcadenomatosis polyposis coli0.919
Fusfusion, derived from t(12;16) malignant liposarcoma (human)0.905
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.903
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.852
Npm1nucleophosmin 10.809
Cct2chaperonin containing Tcp1, subunit 2 (beta)0.795
Gsk3bglycogen synthase kinase 3 beta0.784
Arid1bAT rich interactive domain 1B (SWI-like)0.780
Cct6achaperonin containing Tcp1, subunit 6a (zeta)0.775
Smad4MAD homolog 4 (Drosophila)0.738
Vamp2vesicle-associated membrane protein 20.720
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.686
Hspa8heat shock protein 80.660
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.655
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.645
Bicd2bicaudal D homolog 2 (Drosophila)0.627
Srsf2serine/arginine-rich splicing factor 20.599
SetSET nuclear oncogene0.591
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.585
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.579
Bmpr1abone morphogenetic protein receptor, type 1A0.579
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.565
Dlg4discs, large homolog 4 (Drosophila)0.562
Rac1RAS-related C3 botulinum substrate 10.540
Mtap2microtubule-associated protein 20.536
Ccnd1cyclin D10.535
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.530
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.524
Wdr1WD repeat domain 10.510
Vaspvasodilator-stimulated phosphoprotein0.496
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.493
Dlg2discs, large homolog 2 (Drosophila)0.486
Cops4COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)0.484
Eif4a1eukaryotic translation initiation factor 4A10.484
Vcpvalosin containing protein0.471
Ptges3prostaglandin E synthase 3 (cytosolic)0.466
2500003M10RikRIKEN cDNA 2500003M10 gene0.456
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.447
Eif5aeukaryotic translation initiation factor 5A0.435
Ap2a1adaptor protein complex AP-2, alpha 1 subunit0.432
Caprin1cell cycle associated protein 10.430
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.430
Erhenhancer of rudimentary homolog (Drosophila)0.428
Spnb2spectrin beta 20.418
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.388
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.371
Pdlim5PDZ and LIM domain 50.369
Cltcclathrin, heavy polypeptide (Hc)0.345
Actr3ARP3 actin-related protein 3 homolog (yeast)0.338
Dlg1discs, large homolog 1 (Drosophila)0.337
Hif1ahypoxia inducible factor 1, alpha subunit0.332
Snrpd1small nuclear ribonucleoprotein D10.323
Smad1MAD homolog 1 (Drosophila)0.308
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.290
Mapre1microtubule-associated protein, RP/EB family, member 10.290
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.289
Ccdc64coiled-coil domain containing 640.273
Tsc1tuberous sclerosis 10.263
Ddx3xDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked0.261
Kpnb1karyopherin (importin) beta 10.256
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.254
Ube2nubiquitin-conjugating enzyme E2N0.252
Prkczprotein kinase C, zeta0.252
Snrpbsmall nuclear ribonucleoprotein B0.252
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.251
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.247
Prmt1protein arginine N-methyltransferase 10.243
Shank2SH3/ankyrin domain gene 20.236
Nudcnuclear distribution gene C homolog (Aspergillus)0.233
Stx12syntaxin 120.226
Capzbcapping protein (actin filament) muscle Z-line, beta0.225
Cul3cullin 30.218
Maelmaelstrom homolog (Drosophila)0.215
G3bp1Ras-GTPase-activating protein SH3-domain binding protein 10.211
Tfdp2transcription factor Dp 20.211
Nf2neurofibromatosis 20.210
Arcactivity regulated cytoskeletal-associated protein0.206
1110004F10RikRIKEN cDNA 1110004F10 gene0.205
Prmt5protein arginine N-methyltransferase 50.204
Ewsr1Ewing sarcoma breakpoint region 10.198
Karslysyl-tRNA synthetase0.191
Nedd4neural precursor cell expressed, developmentally down-regulated 40.190
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.187
Pcbp1poly(rC) binding protein 10.186
Nap1l1nucleosome assembly protein 1-like 10.185
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.183
Inainternexin neuronal intermediate filament protein, alpha0.183
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
par-5Protein PAR-50.012
glh-1Protein GLH-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 30.981
ca15bcarbonic anhydrase XV b0.936
piwil2piwi-like 2 (Drosophila)0.842
piwil1piwi-like 1 (Drosophila)0.763
brca2breast cancer 2, early onset0.669
vasavasa homolog0.609
elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.557
orgoogenesis-related gene0.534
dazldaz-like gene0.506
dlg2discs, large (Drosophila) homolog 20.483
zorbaOrb/CPEB-related RNA-binding protein0.459
dlg1discs, large (Drosophila) homolog 10.398
tdrd1tudor domain containing 10.365
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.363
eef1geukaryotic translation elongation factor 1 gamma0.326
eif5aeukaryotic translation initiation factor 5A0.301
nudt9nudix (nucleoside diphosphate linked moiety X)-type motif 90.300
bucbucky ball0.245
rpl3ribosomal protein L30.240
pfn2profilin 20.239
snx6sorting nexin 60.236
rpl23aribosomal protein L23a0.235
dnddead end0.218
ilf2interleukin enhancer binding factor 20.216
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.207
krt8keratin 80.199
cpne1copine I0.192
rnf17ring finger protein 170.190
rap1bRAS related protein 1b0.183
rps4xribosomal protein S4, X-linked0.181
pak2ap21 (CDKN1A)-activated kinase 2a0.181
ef1aelongation factor 1-alpha0.181
hnrnpa0lheterogeneous nuclear ribonucleoprotein A0, like0.178
acsbg2acyl-CoA synthetase bubblegum family member 20.171
rpl4ribosomal protein L40.170
sfrs3bsplicing factor, arginine/serine-rich 3b0.170
tubg1tubulin, gamma 10.168
myl1myosin, light chain 1, alkali; skeletal, fast0.164
cct7chaperonin containing TCP1, subunit 7 (eta)0.161
rps2ribosomal protein S20.159
smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.159
ilkintegrin linked kinase0.157
dynlt3dynein, light chain, Tctex-type 30.157
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.152
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.148
stac3SH3 and cysteine rich domain 30.148
spsb1splA/ryanodine receptor domain and SOCS box containing 10.147
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.146
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.143
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.142
znf711zinc finger protein 7110.141
pdcd6ipprogrammed cell death 6 interacting protein0.139
mpzmyelin protein zero0.138
eif3ceukaryotic translation initiation factor 3, subunit C0.138
ck2bcasein kinase 2 beta0.137
tpt1tumor protein, translationally-controlled 10.135
rpl5bribosomal protein L5b0.134
pkm2apyruvate kinase, muscle, a0.131
rps9ribosomal protein S90.128
flot1bflotillin 1b0.126
gdf9growth differentiation factor 90.123
hnrnpa0heterogeneous nuclear ribonucleoprotein A00.120
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.119
prkd1protein kinase D10.118
rps24ribosomal protein S240.118
eif4a1aeukaryotic translation initiation factor 4A, isoform 1A0.118
esyt3extended synaptotagmin-like protein 30.116
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.115
eif4a1beukaryotic translation initiation factor 4A, isoform 1B0.110
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.108
rpl7aribosomal protein L7a0.107
tnnc2troponin C type 2 (fast)0.107
rpl36aribosomal protein L36A0.106
e2f5E2F transcription factor 50.105
rpl19ribosomal protein L190.100
copebcore promoter element binding protein0.100
rps10ribosomal protein S100.100
stmn2bstathmin-like 2b0.099
sf1splicing factor 10.099
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.098
tdrd7tudor domain containing 70.098
sybusyntabulin (syntaxin-interacting)0.097
tbpl2TATA box binding protein like 20.096
asz1ankyrin repeat, SAM and basic leucine zipper domain containing 10.094
il7rinterleukin 7 receptor0.094
eif3deukaryotic translation initiation factor 3, subunit D0.093
eif3beukaryotic translation initiation factor 3, subunit B0.092
acvr1bactivin A receptor, type IB0.088
gnao1aguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a0.088
rpl10ribosomal protein L100.087
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
BicDBicaudal D1.000
magomago nashi0.998
par-1CG8201 gene product from transcript CG8201-RA0.997
Src64BSrc oncogene at 64B0.992
slmbsupernumerary limbs0.989
Hel25EHelicase at 25E0.985
aPKCatypical protein kinase C0.983
CG6854CG6854 gene product from transcript CG6854-RC0.978
sec5CG8843 gene product from transcript CG8843-RA0.973
pitaCG3941 gene product from transcript CG3941-RA0.967
spn-Espindle E0.964
par-6CG5884 gene product from transcript CG5884-RA0.960
Dhc64CDynein heavy chain 64C0.944
traltrailer hitch0.938
TER94CG2331 gene product from transcript CG2331-RA0.911
sqhspaghetti squash0.903
me31Bmaternal expression at 31B0.901
KhcKinesin heavy chain0.879
Rac1CG2248 gene product from transcript CG2248-RA0.862
CG4771CG4771 gene product from transcript CG4771-RA0.840
CG11188CG11188 gene product from transcript CG11188-RA0.809
ChcClathrin heavy chain0.803
Gprk2G protein-coupled receptor kinase 20.801
DlicDynein light intermediate chain0.800
Dcp1Decapping protein 10.793
Cdc42CG12530 gene product from transcript CG12530-RA0.790
htshu li tai shao0.782
Fmr1CG6203 gene product from transcript CG6203-RC0.777
tho2CG31671 gene product from transcript CG31671-RA0.669
orboo18 RNA-binding protein0.662
cpacapping protein alpha0.656
SRPKCG8174 gene product from transcript CG8174-RA0.633
bratbrain tumor0.604
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.540
Rab6Rab-protein 60.486
CG10260CG10260 gene product from transcript CG10260-RB0.456
RpL10AbRibosomal protein L10Ab0.455
Rab5Rab-protein 50.454
JIL-1CG6297 gene product from transcript CG6297-RA0.425
spn-Aspindle A0.382
Tm1Tropomyosin 10.376
alpha-Specalpha Spectrin0.362
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.345
DpDP transcription factor0.322
CG17838CG17838 gene product from transcript CG17838-RA0.318
cupCG11181 gene product from transcript CG11181-RB0.315
Rab11Rab-protein 110.308
CSN5COP9 complex homolog subunit 50.302
Pi3K21BCG2699 gene product from transcript CG2699-RA0.292
spn-Bspindle B0.283
tauCG31057 gene product from transcript CG31057-RA0.282
spensplit ends0.271
Sop2Suppressor of profilin 20.270
beta-Specbeta Spectrin0.265
4EHPCG33100 gene product from transcript CG33100-RA0.262
Ets97DEts at 97D0.243
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism