The network for 'sensory perception of bitter taste' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sensory perception of bitter taste

The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

NameDescriptionProbabilityFunc Analog Organism
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.992
Grip1glutamate receptor interacting protein 10.621
Dlg4discs, large homolog 4 (Drosophila)0.533
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.339
CblCasitas B-lineage lymphoma0.183
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.108
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.081
Gria3glutamate receptor, ionotropic, AMPA3 (alpha 3)0.068
Itpr2inositol 1,4,5-triphosphate receptor 20.046
Itpr3inositol 1,4,5-triphosphate receptor 30.043
Exoc4exocyst complex component 40.038
Stat3signal transducer and activator of transcription 30.037
Cacng2calcium channel, voltage-dependent, gamma subunit 20.024
Homer1homer homolog 1 (Drosophila)0.024
Tgfb1transforming growth factor, beta 10.022
Plp1proteolipid protein (myelin) 10.020
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.019
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.018
Cdk14cyclin-dependent kinase 140.015
Fliiflightless I homolog (Drosophila)0.013
Pcp2Purkinje cell protein 2 (L7)0.012
Thrathyroid hormone receptor alpha0.012
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.011
Olfr17olfactory receptor 170.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-36Protein EGL-360.095
plc-3Protein PLC-30.091
pdf-1Protein PDF-10.078
pkg-1Protein PKG-10.073
pdfr-1Protein PDFR-10.070
CELE_Y53F4B.5Protein Y53F4B.50.060
gsp-1Protein GSP-10.057
glr-5Protein GLR-50.043
let-23Protein LET-230.036
unc-32Protein UNC-320.035
sir-2.2Protein SIR-2.20.033
pes-7Protein PES-70.033
eat-16Protein EAT-160.032
egl-5Protein EGL-50.029
gpb-1Protein GPB-10.027
cccp-1Protein CCCP-10.026
cal-2Protein CAL-20.025
CELE_M176.5Protein M176.50.025
tax-6Protein TAX-60.025
C01H6.2Protein C01H6.20.024
C03A3.2Protein C03A3.20.023
glr-1Protein GLR-10.022
csnk-1Protein CSNK-10.022
ZK596.3Protein ZK596.30.021
let-607Protein LET-6070.021
grk-2Protein GRK-20.020
goa-1Protein GOA-10.019
vab-8Protein VAB-80.019
math-4Protein MATH-40.019
math-27Protein MATH-270.018
tag-89Protein TAG-890.017
unc-54Protein UNC-540.017
C45G9.6Protein C45G9.60.017
lrp-1Protein LRP-10.016
egl-2Protein EGL-20.016
gpa-16Protein GPA-160.016
catp-5Protein CATP-50.015
gpr-1Protein GPR-10.015
lin-7Protein LIN-70.015
zig-6Protein ZIG-60.014
daf-11Protein DAF-110.014
ZK131.11Protein ZK131.110.014
Y48C3A.5Protein Y48C3A.50.014
unc-29Protein UNC-290.013
acr-15Protein ACR-150.013
odr-1Protein ODR-10.013
F37B12.1Protein F37B12.10.013
eat-4Protein EAT-40.013
math-3Protein MATH-30.012
egl-8Protein EGL-80.012
unc-7Protein UNC-70.012
nmtn-1Protein NMTN-10.012
kcnl-2Protein KCNL-20.012
bar-1Protein BAR-10.012
slo-2Protein SLO-20.011
plc-1Protein PLC-10.011
daf-16Protein DAF-160.011
nhr-136Protein NHR-1360.011
R08E3.2Protein R08E3.20.011
F33C8.4Protein F33C8.40.011
unc-15Protein UNC-150.011
unc-53Protein UNC-530.011
zfh-2Protein ZFH-20.011
ncx-4Protein NCX-40.011
ggr-3Protein GGR-30.010
npr-1Protein NPR-10.010
cutl-22Protein CUTL-220.010
F46B6.6Protein F46B6.60.010
M04C3.1Protein M04C3.10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HLA-Cmajor histocompatibility complex, class I, C1.000
HLA-Fmajor histocompatibility complex, class I, F1.000
HLA-Bmajor histocompatibility complex, class I, B1.000
HLA-Gmajor histocompatibility complex, class I, G0.997
HLA-Amajor histocompatibility complex, class I, A0.996
HLA-Emajor histocompatibility complex, class I, E0.991
TAPBPTAP binding protein (tapasin)0.668
TFF1trefoil factor 10.628
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.390
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.298
LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein0.212
TPP1tripeptidyl peptidase I0.194
CST3cystatin C0.131
SPDEFSAM pointed domain containing ets transcription factor0.085
TAPBPLTAP binding protein-like0.074
CST2cystatin SA0.070
CTSDcathepsin D0.056
CFDcomplement factor D (adipsin)0.052
ISG20interferon stimulated exonuclease gene 20kDa0.044
PGCPplasma glutamate carboxypeptidase0.041
CST4cystatin S0.041
MAN2B1mannosidase, alpha, class 2B, member 10.040
SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 40.039
CD81CD81 molecule0.038
HCP5HLA complex P50.038
TCN2transcobalamin II0.034
IRF1interferon regulatory factor 10.034
NPC2Niemann-Pick disease, type C20.033
CTSAcathepsin A0.033
CTSBcathepsin B0.032
GAAglucosidase, alpha; acid0.030
IL32interleukin 320.029
P2RX4purinergic receptor P2X, ligand-gated ion channel, 40.028
NUCB1nucleobindin 10.028
PLD3phospholipase D family, member 30.025
HK3hexokinase 3 (white cell)0.024
CST1cystatin SN0.023
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.023
NSFN-ethylmaleimide-sensitive factor0.022
IFITM3interferon induced transmembrane protein 3 (1-8U)0.021
FCGRTFc fragment of IgG, receptor, transporter, alpha0.021
TNFSF12-TNFSF13TNFSF12-TNFSF13 readthrough0.021
MYO1Fmyosin IF0.021
SLC22A2solute carrier family 22 (organic cation transporter), member 20.021
CD300CCD300c molecule0.021
TMEM140transmembrane protein 1400.020
CTSOcathepsin O0.020
BATF2basic leucine zipper transcription factor, ATF-like 20.020
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.020
PBXIP1pre-B-cell leukemia homeobox interacting protein 10.019
CACNA1Icalcium channel, voltage-dependent, T type, alpha 1I subunit0.019
BTN3A1butyrophilin, subfamily 3, member A10.019
DNASE2deoxyribonuclease II, lysosomal0.019
FSCN3fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)0.019
SCGB2A2secretoglobin, family 2A, member 20.019
GRIA1glutamate receptor, ionotropic, AMPA 10.018
SIGLEC7sialic acid binding Ig-like lectin 70.017
OR1F1olfactory receptor, family 1, subfamily F, member 10.017
RRHretinal pigment epithelium-derived rhodopsin homolog0.017
SARDHsarcosine dehydrogenase0.017
GPR12G protein-coupled receptor 120.016
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.016
DMBT1deleted in malignant brain tumors 10.016
BTN3A3butyrophilin, subfamily 3, member A30.016
CST5cystatin D0.015
OASL2'-5'-oligoadenylate synthetase-like0.015
PRG3proteoglycan 30.015
LAIR1leukocyte-associated immunoglobulin-like receptor 10.015
RNASELribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)0.014
EPHX1epoxide hydrolase 1, microsomal (xenobiotic)0.014
GPR52G protein-coupled receptor 520.014
OR10H3olfactory receptor, family 10, subfamily H, member 30.014
ODF1outer dense fiber of sperm tails 10.014
TCTN2tectonic family member 20.013
BTNL8butyrophilin-like 80.013
TAS2R50taste receptor, type 2, member 500.013
ABP1amiloride binding protein 1 (amine oxidase (copper-containing))0.013
RNASET2ribonuclease T20.013
GABRR2gamma-aminobutyric acid (GABA) receptor, rho 20.013
TRANK1tetratricopeptide repeat and ankyrin repeat containing 10.013
CLPScolipase, pancreatic0.013
MRGPRX1MAS-related GPR, member X10.013
TAP2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.013
NINJ1ninjurin 10.013
DEFA6defensin, alpha 6, Paneth cell-specific0.013
IL10RBinterleukin 10 receptor, beta0.012
SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi10.012
TBXAS1thromboxane A synthase 1 (platelet)0.012
TRIM38tripartite motif containing 380.012
CSF3Rcolony stimulating factor 3 receptor (granulocyte)0.012
RARRES3retinoic acid receptor responder (tazarotene induced) 30.012
C15orf2chromosome 15 open reading frame 20.012
PI15peptidase inhibitor 150.012
CHRNGcholinergic receptor, nicotinic, gamma0.012
TAS2R4taste receptor, type 2, member 40.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ddx3xDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.021
Cd4Cd4 molecule0.021
Ccr4chemokine (C-C motif) receptor 40.021
Tas2r107taste receptor, type 2, member 1070.020
Stag3stromal antigen 30.020
Tas2r123taste receptor, type 2, member 1230.020
Acmsdaminocarboxymuconate semialdehyde decarboxylase0.019
Ccl22chemokine (C-C motif) ligand 220.019
Ptprdprotein tyrosine phosphatase, receptor type, D0.017
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.016
RGD1562844similar to serine (or cysteine) proteinase inhibitor, clade B, member 90.016
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.016
Ces2ccarboxylesterase 2C0.016
Vat1vesicle amine transport protein 1 homolog (T californica)0.016
Serpinb12serpin peptidase inhibitor, clade B (ovalbumin), member 120.016
Gpr149G protein-coupled receptor 1490.015
Cx3cr1chemokine (C-X3-C motif) receptor 10.015
Tmem45btransmembrane protein 45b0.015
Akt2v-akt murine thymoma viral oncogene homolog 20.015
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.015
Tas2r121taste receptor, type 2, member 1210.015
Mogmyelin oligodendrocyte glycoprotein0.015
Bcl2l10BCL2-like 10 (apoptosis facilitator)0.014
Duox2dual oxidase 20.014
Ido1indoleamine 2,3-dioxygenase 10.014
Cyp2b21cytochrome P450, family 2, subfamily b, polypeptide 210.014
Phox2apaired-like homeobox 2a0.014
Cysltr2cysteinyl leukotriene receptor 20.014
Mfrpmembrane frizzled-related protein0.014
Ust5rintegral membrane transport protein UST5r0.014
Sypl2synaptophysin-like 20.014
Magt1magnesium transporter 10.014
Ctsqcathepsin Q0.014
Vom1r101vomeronasal 1 receptor 1010.014
Prl7a4prolactin family 7, subfamily a, member 40.014
Accn5amiloride-sensitive cation channel 5, intestinal0.014
Prl3c1Prolactin family 3, subfamily c, member 10.014
Dbil5diazepam binding inhibitor-like 50.014
Inhbcinhibin beta C0.014
Fgf11fibroblast growth factor 110.014
Cacng7calcium channel, voltage-dependent, gamma subunit 70.013
Tas2r118taste receptor, type 2, member 1180.013
Gpr173G-protein coupled receptor 1730.013
Prl7d1prolactin family 7, subfamily d, member 10.013
C8bcomplement component 8, beta polypeptide0.013
Prss21protease, serine, 210.013
Sval2seminal vesicle antigen-like 20.013
Bmp15bone morphogenetic protein 150.013
Ly6g6elymphocyte antigen 6 complex, locus G6E0.013
Pcyt1bphosphate cytidylyltransferase 1, choline, beta0.013
Rap1bRAP1B, member of RAS oncogene family0.013
Gucy1b3guanylate cyclase 1, soluble, beta 30.013
Ush1cUsher syndrome 1C homolog (human)0.013
Syt4synaptotagmin IV0.013
Slc22a9solute carrier family 22 (organic anion transporter), member 90.013
Itpr1inositol 1,4,5-triphosphate receptor, type 10.013
Myo1dmyosin ID0.013
Foxc1forkhead box C10.013
Toretrispanning orphan0.013
Chrna10cholinergic receptor, nicotinic, alpha 100.013
Capn13calpain 130.013
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.013
Kcnv1potassium channel, subfamily V, member 10.013
Trpm8transient receptor potential cation channel, subfamily M, member 80.013
Klhl6kelch-like 6 (Drosophila)0.013
Slc5a7solute carrier family 5 (choline transporter), member 70.013
Lamb2laminin, beta 20.013
Osbp2oxysterol binding protein 20.012
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.012
Slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.012
Ccl28chemokine (C-C motif) ligand 280.012
Arhgef9Cdc42 guanine nucleotide exchange factor (GEF) 90.012
Icosinducible T-cell co-stimulator0.012
Gdf9growth differentiation factor 90.012
Il8rainterleukin 8 receptor, alpha0.012
Flt1FMS-related tyrosine kinase 10.012
Fgf15fibroblast growth factor 150.012
Clic4chloride intracellular channel 40.012
Csn3casein kappa0.012
Robo2roundabout homolog 2 (Drosophila)0.012
Rbp3retinol binding protein 3, interstitial0.012
Hrh4histamine receptor H40.012
Slco1b3solute carrier organic anion transporter family, member 1b30.012
Vom1r102vomeronasal 1 receptor 1020.012
Zbp1Z-DNA binding protein 10.012
Prl7a3prolactin family 7, subfamily a, member 30.012
Prl2b1Prolactin family 2, subfamily b, member 10.012
Il17finterleukin 17F0.012
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.012
Dnase2bdeoxyribonuclease II beta0.012
Ntsr2neurotensin receptor 20.012
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.012
Sorbs3sorbin and SH3 domain containing 30.012
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.012
Hrchistidine rich calcium binding protein0.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism