The network for 'protein neddylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein neddylation

Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.

NameDescriptionProbabilityFunc Analog Organism
Vbp1von Hippel-Lindau binding protein 10.837
Psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.665
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.454
Cetn3centrin 30.450
Arl1ADP-ribosylation factor-like 10.296
Uba3ubiquitin-like modifier activating enzyme 30.273
Cacybpcalcyclin binding protein0.231
Ube2e1ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast)0.225
Mffmitochondrial fission factor0.192
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.141
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.102
Ergic2ERGIC and golgi 20.099
Cetn2centrin 20.090
Mterfd1MTERF domain containing 10.079
Sumo1SMT3 suppressor of mif two 3 homolog 1 (yeast)0.077
Spcs1signal peptidase complex subunit 1 homolog (S. cerevisiae)0.075
Sept7septin 70.064
Tceb1transcription elongation factor B (SIII), polypeptide 10.064
Vdac3voltage-dependent anion channel 30.064
Paip2polyadenylate-binding protein-interacting protein 20.055
Fkbp3FK506 binding protein 30.055
Snrnp27small nuclear ribonucleoprotein 27 (U4/U6.U5)0.054
Cwc15CWC15 homolog (S. cerevisiae)0.054
Dync1i2dynein cytoplasmic 1 intermediate chain 20.054
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.051
Psmb7proteasome (prosome, macropain) subunit, beta type 70.048
Pcmt1protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.046
Pdcl3phosducin-like 30.046
SarnpSAP domain containing ribonucleoprotein0.045
Ube2aubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae)0.042
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.040
IkIK cytokine0.039
Bcap29B-cell receptor-associated protein 290.036
Zfp51zinc finger protein 510.036
Tbcatubulin cofactor A0.035
Rab5aRAB5A, member RAS oncogene family0.035
C1dC1D nuclear receptor co-repressor0.034
Psma2proteasome (prosome, macropain) subunit, alpha type 20.033
Psmb5proteasome (prosome, macropain) subunit, beta type 50.033
Scocshort coiled-coil protein0.032
Nae1NEDD8 activating enzyme E1 subunit 10.032
Srp14signal recognition particle 140.032
Rad17RAD17 homolog (S. pombe)0.031
Zranb2zinc finger, RAN-binding domain containing 20.027
Ccdc90bcoiled-coil domain containing 90B0.026
Orc4origin recognition complex, subunit 40.023
SsbSjogren syndrome antigen B0.023
Criptcysteine-rich PDZ-binding protein0.023
Hras1Harvey rat sarcoma virus oncogene 10.022
Med21mediator complex subunit 210.022
Csnk2bcasein kinase 2, beta polypeptide0.022
Mmadhcmethylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria0.022
Txndc9thioredoxin domain containing 90.022
RhebRas homolog enriched in brain0.022
Gtf2a2general transcription factor II A, 20.019
Cul4acullin 4A0.019
Pompproteasome maturation protein0.019
Rab28RAB28, member RAS oncogene family0.019
Taf9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.019
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.018
Gtf2e2general transcription factor II E, polypeptide 2 (beta subunit)0.018
Fyttd1forty-two-three domain containing 10.018
Itgb1bp1integrin beta 1 binding protein 10.017
Ccng1cyclin G10.017
1110004F10RikRIKEN cDNA 1110004F10 gene0.017
1810035L17RikRIKEN cDNA 1810035L17 gene0.017
2410004B18RikRIKEN cDNA 2410004B18 gene0.017
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.016
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.016
Znrd1zinc ribbon domain containing, 10.015
Dctn3dynactin 30.015
Dlddihydrolipoamide dehydrogenase0.014
Zfp644zinc finger protein 6440.014
0610009D07RikRIKEN cDNA 0610009D07 gene0.013
Rab18RAB18, member RAS oncogene family0.013
FastkFas-activated serine/threonine kinase0.013
Tmem30atransmembrane protein 30A0.013
Zfp639zinc finger protein 6390.012
Vps29vacuolar protein sorting 29 (S. pombe)0.012
Vapavesicle-associated membrane protein, associated protein A0.012
6330577E15RikRIKEN cDNA 6330577E15 gene0.012
Mrps33mitochondrial ribosomal protein S330.012
Tbcbtubulin folding cofactor B0.012
Polr2kpolymerase (RNA) II (DNA directed) polypeptide K0.011
Immp1lIMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)0.011
Mrpl32mitochondrial ribosomal protein L320.011
Hiat1hippocampus abundant gene transcript 10.011
Pkm2pyruvate kinase, muscle0.011
Pin1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 10.011
Fam103a1family with sequence similarity 103, member A10.011
Rab11aRAB11a, member RAS oncogene family0.010
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.010
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.010
Mrpl20mitochondrial ribosomal protein L200.010
2900010J23RikRIKEN cDNA 2900010J23 gene0.010
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.010
Fis1fission 1 (mitochondrial outer membrane) homolog (yeast)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sac-1Protein SAC-10.102
F56A8.5Protein F56A8.50.096
smo-1Protein SMO-10.076
CELE_C34D4.4Protein C34D4.40.050
snr-3Protein SNR-30.037
pabp-2Protein PABP-20.037
ubc-18Protein UBC-180.036
perm-3Protein PERM-30.034
his-68Protein HIS-680.029
rbx-1Protein RBX-10.029
F35H10.5Protein F35H10.50.028
C35D10.13Protein C35D10.130.026
ZK632.10Protein ZK632.100.022
his-45Protein HIS-450.022
atg-18Protein ATG-180.020
ubc-3Protein UBC-30.020
F39B2.3Protein F39B2.30.019
dpy-30Protein DPY-300.019
lsm-5Protein LSM-50.019
rab-10Protein RAB-100.018
tag-322Protein TAG-3220.018
mdt-18Protein MDT-180.016
ftr-1Protein FTR-10.016
rpa-2Protein RPA-20.016
his-48Protein HIS-480.015
rab-6.1Protein RAB-6.10.015
T01G9.2Protein T01G9.20.015
C01A2.5Protein C01A2.50.015
F54C4.4Protein F54C4.40.014
F08G12.2Protein F08G12.20.014
F10G8.6Protein F10G8.60.014
skr-2Protein SKR-20.014
mdf-1Protein MDF-10.013
CELE_C01G6.4Protein C01G6.40.012
baf-1Protein BAF-10.012
T26A5.8Protein T26A5.80.012
F37B4.10Protein F37B4.100.012
C48B6.9Protein C48B6.90.012
rom-1Protein ROM-10.011
emb-1Protein EMB-10.011
rpb-7Protein RPB-70.011
mag-1Protein MAG-10.011
F22B5.10Protein F22B5.100.011
cyn-12Protein CYN-120.011
C02F5.3Protein C02F5.30.010
C01G5.6Protein C01G5.60.010
C16C8.11Protein C16C8.110.010
F59E10.3Protein F59E10.30.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
asf1anti-silencing factor 10.075
Rpt4CG3455 gene product from transcript CG3455-RA0.028
RpII33RNA polymerase II 33kD subunit0.021
Cbp20cap binding protein 200.021
Dim1CG3058 gene product from transcript CG3058-RA0.020
Rpn7CG5378 gene product from transcript CG5378-RA0.019
Rpt1CG1341 gene product from transcript CG1341-RA0.018
Rpn12CG4157 gene product from transcript CG4157-RA0.016
Pros54Proteasome 54kD subunit0.016
Uch-L3Ubiquitin C-terminal hydrolase0.015
RnpS1RNA-binding protein S10.015
CSN7COP9 complex homolog subunit 70.014
Mfap1Microfibril-associated protein 10.014
Bap55Brahma associated protein 55kD0.014
Rpn9CG10230 gene product from transcript CG10230-RB0.014
Nedd8CG10679 gene product from transcript CG10679-RA0.014
pontpontin0.013
CG9548CG9548 gene product from transcript CG9548-RA0.013
ublubiquitin like0.012
CG13779CG13779 gene product from transcript CG13779-RA0.012
TfIIEalphaTranscription factor IIEalpha0.012
Nurf-38Nucleosome remodeling factor - 38kD0.012
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.011
Rpn6Proteasome p44.5 subunit0.011
SelDSelenide,water dikinase0.010
Rbsn-5Rabenosyn-50.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CUL1cullin 11.000
RBX1ring-box 1, E3 ubiquitin protein ligase0.998
NEDD8neural precursor cell expressed, developmentally down-regulated 80.979
UBE2Mubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)0.518
CUL5cullin 50.401
BTRCbeta-transducin repeat containing0.123
FBXW2F-box and WD repeat domain containing 20.101
FBXW11F-box and WD repeat domain containing 110.089
CUL2cullin 20.076
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.076
SKP1S-phase kinase-associated protein 10.074
NUB1negative regulator of ubiquitin-like proteins 10.058
FBXO33F-box protein 330.043
CAND1cullin-associated and neddylation-dissociated 10.033
SKP2S-phase kinase-associated protein 2 (p45)0.033
FBXW7F-box and WD repeat domain containing 70.028
FBXO4F-box protein 40.025
CDC34cell division cycle 34 homolog (S. cerevisiae)0.013
RPL11ribosomal protein L110.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmb3proteasome (prosome, macropain) subunit, beta type 30.030
LOC100361944hypothetical protein LOC1003619440.029
RanRAN, member RAS oncogene family0.024
Serinc1serine incorporator 10.019
Rtcd1RNA terminal phosphate cyclase domain 10.015
Mterfd1MTERF domain containing 10.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism