The network for 'rna phosphodiester bond hydrolysis exonucleolytic' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rna phosphodiester bond hydrolysis exonucleolytic

The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.

NameDescriptionProbabilityFunc Analog Organism
Cnot6CCR4-NOT transcription complex, subunit 60.435
Xpo1exportin 1, CRM1 homolog (yeast)0.163
Ndufaf4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 40.114
Dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.102
Cbfbcore binding factor beta0.085
Nup54nucleoporin 540.083
Msh6mutS homolog 6 (E. coli)0.081
Gspt1G1 to S phase transition 10.080
Nolc1nucleolar and coiled-body phosphoprotein 10.074
Rcor1REST corepressor 10.072
2410042D21RikRIKEN cDNA 2410042D21 gene0.067
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.065
Prps1l3phosphoribosyl pyrophosphate synthetase 1-like 30.058
G2e3G2/M-phase specific E3 ubiquitin ligase0.054
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.052
Utp6UTP6, small subunit (SSU) processome component, homolog (yeast)0.047
Actl6aactin-like 6A0.046
Cnot7CCR4-NOT transcription complex, subunit 70.044
Nupl1nucleoporin like 10.041
McmbpMCM (minichromosome maintenance deficient) binding protein0.040
Pbrm1polybromo 10.038
Dhx16DEAH (Asp-Glu-Ala-His) box polypeptide 160.035
Nipa2non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)0.034
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.034
Rqcd1rcd1 (required for cell differentiation) homolog 1 (S. pombe)0.032
Mbtd1mbt domain containing 10.029
Erbb2ipErbb2 interacting protein0.028
B230219D22RikRIKEN cDNA B230219D22 gene0.027
Pdss1prenyl (solanesyl) diphosphate synthase, subunit 10.027
Pum2pumilio 2 (Drosophila)0.027
Ddx21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.027
Ncapg2non-SMC condensin II complex, subunit G20.027
Lrrc40leucine rich repeat containing 400.025
Ppatphosphoribosyl pyrophosphate amidotransferase0.024
Fastkd5FAST kinase domains 50.024
Kpna3karyopherin (importin) alpha 30.024
Dbr1debranching enzyme homolog 1 (S. cerevisiae)0.023
Smc5structural maintenance of chromosomes 50.023
Pds5aPDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.023
Rbm12RNA binding motif protein 120.023
Ints2integrator complex subunit 20.023
Ppp1r8protein phosphatase 1, regulatory (inhibitor) subunit 80.022
Mis12MIS12 homolog (yeast)0.022
Etaa1Ewing's tumor-associated antigen 10.022
BccipBRCA2 and CDKN1A interacting protein0.021
B230308N11RikRIKEN cDNA B230308N11 gene0.021
1700029F09RikRIKEN cDNA 1700029F09 gene0.020
Rfx7regulatory factor X, 70.019
Zcchc11zinc finger, CCHC domain containing 110.019
Srsf10serine/arginine-rich splicing factor 100.019
Lin7clin-7 homolog C (C. elegans)0.019
Casp2caspase 20.018
Donsondownstream neighbor of SON0.018
Nup153nucleoporin 1530.018
Nudcd2NudC domain containing 20.018
Cpsf6cleavage and polyadenylation specific factor 60.017
Nufip1nuclear fragile X mental retardation protein interacting protein 10.017
Nup155nucleoporin 1550.017
Rfwd3ring finger and WD repeat domain 30.017
Smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.017
Nup35nucleoporin 350.016
Map3k1mitogen-activated protein kinase kinase kinase 10.016
Cul2cullin 20.016
Tipintimeless interacting protein0.016
Ptpn12protein tyrosine phosphatase, non-receptor type 120.016
Abce1ATP-binding cassette, sub-family E (OABP), member 10.015
Vps54vacuolar protein sorting 54 (yeast)0.015
Wdr36WD repeat domain 360.015
Acin1apoptotic chromatin condensation inducer 10.015
Sfswapsplicing factor, suppressor of white-apricot homolog (Drosophila)0.015
Abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 70.015
Rrp15ribosomal RNA processing 15 homolog (S. cerevisiae)0.015
Fastkd2FAST kinase domains 20.015
Eri1exoribonuclease 10.014
Cdc23CDC23 (cell division cycle 23, yeast, homolog)0.014
Rsl1d1ribosomal L1 domain containing 10.014
Rbbp8retinoblastoma binding protein 80.014
Gtf3c2general transcription factor IIIC, polypeptide 2, beta0.014
Rp2hretinitis pigmentosa 2 homolog (human)0.014
Eef1e1eukaryotic translation elongation factor 1 epsilon 10.014
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.014
Dckdeoxycytidine kinase0.014
Caprin1cell cycle associated protein 10.014
Xrcc5X-ray repair complementing defective repair in Chinese hamster cells 50.014
Rpp40ribonuclease P 40 subunit (human)0.014
Baz1abromodomain adjacent to zinc finger domain 1A0.014
Ddx39DEAD (Asp-Glu-Ala-Asp) box polypeptide 390.013
Isg20l2interferon stimulated exonuclease gene 20-like 20.013
Taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.013
Zfc3h1zinc finger, C3H1-type containing0.013
Thoc5THO complex 50.013
Phippleckstrin homology domain interacting protein0.013
Mlh1mutL homolog 1 (E. coli)0.013
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.013
Haus6HAUS augmin-like complex, subunit 60.013
Zfp280czinc finger protein 280C0.013
Srsf7serine/arginine-rich splicing factor 70.013
Phf6PHD finger protein 60.013
Mier3mesoderm induction early response 1, family member 30.012
Appbp2amyloid beta precursor protein (cytoplasmic tail) binding protein 20.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Hrb98DEHeterogeneous nuclear ribonucleoprotein at 98DE0.029
CG7845CG7845 gene product from transcript CG7845-RB0.024
l(3)05822lethal (3) 058220.022
CG4159CG4159 gene product from transcript CG4159-RA0.021
CG7611CG7611 gene product from transcript CG7611-RJ0.020
RanGapRan GTPase activating protein0.020
Mtr3CG8025 gene product from transcript CG8025-RA0.018
eIF6CG17611 gene product from transcript CG17611-RA0.017
Ars2CG7843 gene product from transcript CG7843-RA0.016
CG1943CG1943 gene product from transcript CG1943-RA0.015
borrborealin-related0.015
PtpmegCG1228 gene product from transcript CG1228-RD0.015
l(1)G0004lethal (1) G00040.014
CG11107CG11107 gene product from transcript CG11107-RA0.014
wacwee Augmin0.014
CG4887CG4887 gene product from transcript CG4887-RA0.014
Nop56CG13849 gene product from transcript CG13849-RA0.014
CG14543CG14543 gene product from transcript CG14543-RA0.014
Atg18Autophagy-specific gene 180.013
Art8Arginine methyltransferase 80.012
squsquash0.012
CG11583CG11583 gene product from transcript CG11583-RA0.012
kelkelch0.012
Ski6CG15481 gene product from transcript CG15481-RA0.012
CG9286CG9286 gene product from transcript CG9286-RA0.011
Sas10CG4202 gene product from transcript CG4202-RA0.011
Hsc70CbCG6603 gene product from transcript CG6603-RG0.011
CG1542CG1542 gene product from transcript CG1542-RA0.011
CG7006CG7006 gene product from transcript CG7006-RA0.011
Prp31CG6876 gene product from transcript CG6876-RA0.011
CG7275CG7275 gene product from transcript CG7275-RA0.011
CG4364CG4364 gene product from transcript CG4364-RA0.011
CG4038CG4038 gene product from transcript CG4038-RA0.010
Xe7CG2179 gene product from transcript CG2179-RA0.010
OteOtefin0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EXOSC3exosome component 31.000
EXOSC10exosome component 101.000
DIS3LDIS3 mitotic control homolog (S. cerevisiae)-like1.000
EXOSC7exosome component 70.999
EXOSC2exosome component 20.998
EXOSC1exosome component 10.998
EXOSC9exosome component 90.996
CNOT1CCR4-NOT transcription complex, subunit 10.988
EXOSC5exosome component 50.982
CNOT6CCR4-NOT transcription complex, subunit 60.980
EXOSC4exosome component 40.965
CNOT7CCR4-NOT transcription complex, subunit 70.944
BTG1B-cell translocation gene 1, anti-proliferative0.889
EXOSC8exosome component 80.872
DIS3DIS3 mitotic control homolog (S. cerevisiae)0.808
CNOT6LCCR4-NOT transcription complex, subunit 6-like0.383
CNOT8CCR4-NOT transcription complex, subunit 80.367
CNOT2CCR4-NOT transcription complex, subunit 20.257
PABPC1poly(A) binding protein, cytoplasmic 10.250
TNRC6Atrinucleotide repeat containing 6A0.153
TNRC6Btrinucleotide repeat containing 6B0.148
UPF2UPF2 regulator of nonsense transcripts homolog (yeast)0.148
CNOT10CCR4-NOT transcription complex, subunit 100.122
CNOT3CCR4-NOT transcription complex, subunit 30.108
MPHOSPH6M-phase phosphoprotein 60.108
TOB1transducer of ERBB2, 10.060
PAN2PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.039
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.034
RQCD1RCD1 required for cell differentiation1 homolog (S. pombe)0.024
XPO7exportin 70.018
TARDBPTAR DNA binding protein0.017
BTG2BTG family, member 20.017
MOCS3molybdenum cofactor synthesis 30.013
GFM2G elongation factor, mitochondrial 20.011
PAIP2poly(A) binding protein interacting protein 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RRP45Rrp45p0.983
CSL4Csl4p0.954
RRP46Rrp46p0.902
MTR3Mtr3p0.809
RRP40Rrp40p0.788
SKI7Ski7p0.786
DIS3Dis3p0.661
RRP42Rrp42p0.617
MPP6Mpp6p0.614
SKI6Ski6p0.606
RRP4Rrp4p0.551
CAF40Caf40p0.334
RRP6Rrp6p0.233
THG1Thg1p0.201
RRP43Rrp43p0.152
RPF1Rpf1p0.151
LRP1Lrp1p0.121
DBP5Dbp5p0.078
YIR035Chypothetical protein0.060
POP6Pop6p0.046
URA3Ura3p0.042
AIR1Air1p0.036
IMD2Imd2p0.035
YLR264C-Ahypothetical protein0.035
SRD1Srd1p0.034
NRD1Nrd1p0.034
MEX67Mex67p0.033
ARG8Arg8p0.031
MER1Mer1p0.030
SCC2Scc2p0.029
YLR162Whypothetical protein0.028
LEU2Leu2p0.028
SNU13Snu13p0.027
NIP7Nip7p0.027
YIL151Chypothetical protein0.027
ARP10Arp10p0.026
YOL038C-Ahypothetical protein0.026
PRS2Prs2p0.026
FSH1Fsh1p0.025
RPL8BRpl8bp0.025
CLU1Clu1p0.025
MPT5Mpt5p0.025
HOHop0.024
YLR042Chypothetical protein0.023
HXT3Hxt3p0.023
CRP1Crp1p0.022
PAB1Pab1p0.022
YPR157Whypothetical protein0.021
RRP15Rrp15p0.021
YAR068Whypothetical protein0.021
ATP6Atp6p0.021
SWC7Swc7p0.021
YJL181Whypothetical protein0.020
CUP1-1Cup1-1p0.020
BSC1Bsc1p0.019
YBR013Chypothetical protein0.019
CIC1Cic1p0.019
AUA1Aua1p0.018
FMT1Fmt1p0.018
ADH2Adh2p0.018
HPF1Hpf1p0.018
ZPS1Zps1p0.018
MF(ALPHA)2Mf(alpha)2p0.018
IZH4Izh4p0.017
SCM4Scm4p0.017
PTR2Ptr2p0.017
RRN5Rrn5p0.017
OPT2Opt2p0.017
YOL013W-Ahypothetical protein0.017
TAD2Tad2p0.017
YPR096Chypothetical protein0.016
NRG2Nrg2p0.016
TSC3Tsc3p0.016
RPL39Rpl39p0.016
YLR363W-Ahypothetical protein0.016
YLR040Chypothetical protein0.016
STD1Std1p0.016
COS12Cos12p0.016
CHA1Cha1p0.016
YJL107Chypothetical protein0.015
NOP10Nop10p0.015
CPD1Cpd1p0.015
UPS3Ups3p0.015
RPS4BRps4bp0.015
TIM50Tim50p0.015
YAL037C-Ahypothetical protein0.015
BNA4Bna4p0.015
YAR066Whypothetical protein0.015
SUP35Sup35p0.015
URA6Ura6p0.015
GYL1Gyl1p0.015
RNP1Rnp1p0.015
DIC1Dic1p0.014
YAL064Whypothetical protein0.014
SPS4Sps4p0.014
DIF1Dif1p0.014
PAP2Pap2p0.014
SPL2Spl2p0.014
SUT2Sut2p0.014
PTI1Pti1p0.014