The network for 'regulation of nitric oxide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of nitric oxide biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

NameDescriptionProbabilityFunc Analog Organism
Tlr4toll-like receptor 40.866
Lyz2lysozyme 20.754
Leprleptin receptor0.612
Nos2nitric oxide synthase 2, inducible0.608
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.564
Il6interleukin 60.540
Nos1nitric oxide synthase 1, neuronal0.513
Tnftumor necrosis factor0.486
Klrk1killer cell lectin-like receptor subfamily K, member 10.479
Myd88myeloid differentiation primary response gene 880.478
Klra9killer cell lectin-like receptor subfamily A, member 90.370
Ccr2chemokine (C-C motif) receptor 20.355
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.269
Ccl2chemokine (C-C motif) ligand 20.237
Vdrvitamin D receptor0.233
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.212
Tlr2toll-like receptor 20.176
Il10interleukin 100.176
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.147
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.129
AF251705cDNA sequence AF2517050.122
H2-Q7histocompatibility 2, Q region locus 70.117
Ncr1natural cytotoxicity triggering receptor 10.098
Csf1colony stimulating factor 1 (macrophage)0.094
Socs1suppressor of cytokine signaling 10.078
H2-D1histocompatibility 2, D region locus 10.073
Mmp9matrix metallopeptidase 90.071
Tgfb1transforming growth factor, beta 10.071
Cd44CD44 antigen0.070
Cav1caveolin 1, caveolae protein0.070
Il1ainterleukin 1 alpha0.068
Ren1renin 1 structural0.063
FaslFas ligand (TNF superfamily, member 6)0.063
H2-K1histocompatibility 2, K1, K region0.063
Ppargperoxisome proliferator activated receptor gamma0.061
Insrinsulin receptor0.061
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.061
Pyhin1pyrin and HIN domain family, member 10.054
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.052
Ptenphosphatase and tensin homolog0.049
Nos3nitric oxide synthase 3, endothelial cell0.048
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.048
B2mbeta-2 microglobulin0.046
Cd14CD14 antigen0.042
Map3k8mitogen-activated protein kinase kinase kinase 80.041
Klrc1killer cell lectin-like receptor subfamily C, member 10.038
Gzmkgranzyme K0.038
Klra3killer cell lectin-like receptor, subfamily A, member 30.037
Lair1leukocyte-associated Ig-like receptor 10.036
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.035
Smad3MAD homolog 3 (Drosophila)0.035
Ptrfpolymerase I and transcript release factor0.033
Arandrogen receptor0.032
Klra7killer cell lectin-like receptor, subfamily A, member 70.032
TapbpTAP binding protein0.032
Ccr5chemokine (C-C motif) receptor 50.030
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.030
Gzmagranzyme A0.030
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.030
Bcar1breast cancer anti-estrogen resistance 10.029
Gzmbgranzyme B0.029
Bcl3B-cell leukemia/lymphoma 30.028
Dmddystrophin, muscular dystrophy0.028
Irg1immunoresponsive gene 10.028
Slfn2schlafen 20.028
Clec4eC-type lectin domain family 4, member e0.028
Cxcl9chemokine (C-X-C motif) ligand 90.027
Cxcl1chemokine (C-X-C motif) ligand 10.027
Casp4caspase 4, apoptosis-related cysteine peptidase0.026
Hspa8heat shock protein 80.026
Stat6signal transducer and activator of transcription 60.025
Nr3c1nuclear receptor subfamily 3, group C, member 10.025
Ms4a4cmembrane-spanning 4-domains, subfamily A, member 4C0.024
Aoahacyloxyacyl hydrolase0.024
Meox2mesenchyme homeobox 20.024
Ccl3chemokine (C-C motif) ligand 30.024
Il18rapinterleukin 18 receptor accessory protein0.024
Saa4serum amyloid A 40.023
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.023
Klrd1killer cell lectin-like receptor, subfamily D, member 10.023
Fpr3formyl peptide receptor 30.023
Cxcl10chemokine (C-X-C motif) ligand 100.023
Cxcl2chemokine (C-X-C motif) ligand 20.023
Il7rinterleukin 7 receptor0.023
Slfn1schlafen 10.023
Il1rninterleukin 1 receptor antagonist0.023
Akt1thymoma viral proto-oncogene 10.023
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.022
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.022
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.022
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.021
CblbCasitas B-lineage lymphoma b0.020
Slc12a1solute carrier family 12, member 10.020
Agtr1aangiotensin II receptor, type 1a0.020
Itgb1integrin beta 1 (fibronectin receptor beta)0.020
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.020
F2rl2coagulation factor II (thrombin) receptor-like 20.019
Clec4dC-type lectin domain family 4, member d0.019
Slfn4schlafen 40.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.388
S6kRPS6-p70-protein kinase0.065
Akt1CG4006 gene product from transcript CG4006-RA0.064
InRInsulin-like receptor0.043
chicoCG5686 gene product from transcript CG5686-RB0.031
Atg1Autophagy-specific gene 10.020
TpiTriose phosphate isomerase0.019
foxoforkhead box, sub-group O0.018
drddrop dead0.017
Pk61CProtein kinase 61C0.016
DreddDeath related ced-3/Nedd2-like protein0.012
Ras85DRas oncogene at 85D0.011
RhebCG1081 gene product from transcript CG1081-RA0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.999
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.977
TNFAIP3tumor necrosis factor, alpha-induced protein 30.851
IL1R1interleukin 1 receptor, type I0.775
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.750
IRAK2interleukin-1 receptor-associated kinase 20.540
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.494
TICAM2toll-like receptor adaptor molecule 20.298
IL1Binterleukin 1, beta0.251
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.246
PTPN1protein tyrosine phosphatase, non-receptor type 10.244
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.244
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.234
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.199
TNIP1TNFAIP3 interacting protein 10.196
INSRinsulin receptor0.189
KLF4Kruppel-like factor 4 (gut)0.170
IGF1Rinsulin-like growth factor 1 receptor0.166
TNIP2TNFAIP3 interacting protein 20.134
IL1RAPinterleukin 1 receptor accessory protein0.119
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.088
CAV1caveolin 1, caveolae protein, 22kDa0.083
NCF1neutrophil cytosolic factor 10.080
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.079
KLF6Kruppel-like factor 60.078
MAP3K8mitogen-activated protein kinase kinase kinase 80.077
NOXA1NADPH oxidase activator 10.074
IL8interleukin 80.065
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.063
PRKCZprotein kinase C, zeta0.057
IL10RAinterleukin 10 receptor, alpha0.056
BCAR1breast cancer anti-estrogen resistance 10.056
DLG2discs, large homolog 2 (Drosophila)0.044
CTBP1C-terminal binding protein 10.044
PKD1polycystic kidney disease 1 (autosomal dominant)0.044
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.043
BCL3B-cell CLL/lymphoma 30.040
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.034
STAT5Asignal transducer and activator of transcription 5A0.034
DUSP1dual specificity phosphatase 10.034
MPDZmultiple PDZ domain protein0.033
CCL20chemokine (C-C motif) ligand 200.030
LY96lymphocyte antigen 960.030
IL1RNinterleukin 1 receptor antagonist0.029
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.029
IFNGR1interferon gamma receptor 10.029
EGR2early growth response 20.029
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.028
FOSFBJ murine osteosarcoma viral oncogene homolog0.028
IL1R2interleukin 1 receptor, type II0.026
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.025
FOSL2FOS-like antigen 20.025
TRPC1transient receptor potential cation channel, subfamily C, member 10.024
BIRC3baculoviral IAP repeat containing 30.024
SSTR2somatostatin receptor 20.024
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.023
NTRK1neurotrophic tyrosine kinase, receptor, type 10.023
JUNBjun B proto-oncogene0.023
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.023
SH2D1ASH2 domain containing 1A0.022
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.021
SOCS1suppressor of cytokine signaling 10.021
GHRgrowth hormone receptor0.021
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.021
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.020
MATKmegakaryocyte-associated tyrosine kinase0.020
DDR2discoidin domain receptor tyrosine kinase 20.019
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.019
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.019
MYLK2myosin light chain kinase 20.019
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.019
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.018
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.018
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.018
PPP5Cprotein phosphatase 5, catalytic subunit0.018
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.017
EPORerythropoietin receptor0.017
ICAM1intercellular adhesion molecule 10.017
FYNFYN oncogene related to SRC, FGR, YES0.016
DLG1discs, large homolog 1 (Drosophila)0.016
SH3RF1SH3 domain containing ring finger 10.016
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.016
APPamyloid beta (A4) precursor protein0.015
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.015
MAP2K4mitogen-activated protein kinase kinase 40.015
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.015
PLAURplasminogen activator, urokinase receptor0.015
IRS1insulin receptor substrate 10.015
NAMPTnicotinamide phosphoribosyltransferase0.015
SMAD3SMAD family member 30.014
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.014
NFIL3nuclear factor, interleukin 3 regulated0.014
CARD11caspase recruitment domain family, member 110.014
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.014
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.013
PRKCDprotein kinase C, delta0.013
CXCL2chemokine (C-X-C motif) ligand 20.012
IL6interleukin 6 (interferon, beta 2)0.012
FTH1ferritin, heavy polypeptide 10.012
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.029
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.026
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.023
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.019
Eef2eukaryotic translation elongation factor 20.018
Arf6ADP-ribosylation factor 60.015
Spp2secreted phosphoprotein 20.014
Cx3cl1chemokine (C-X3-C motif) ligand 10.014
Ccr2chemokine (C-C motif) receptor 20.014
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.013
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.013
Irs1insulin receptor substrate 10.013
Irf1interferon regulatory factor 10.013
C4bpacomplement component 4 binding protein, alpha0.013
Hsph1heat shock 105/110 protein 10.012
Hspb1heat shock protein 10.012
Cd2Cd2 molecule0.012
Fmnl1formin-like 10.012
Arrb1arrestin, beta 10.012
Rgs14regulator of G-protein signaling 140.011
Odf3bouter dense fiber of sperm tails 3B0.011
Foxa3forkhead box A30.011
Apoa5apolipoprotein A-V0.011
AhnakAHNAK nucleoprotein0.011
Mbl1mannose-binding lectin (protein A) 10.011
Hist1h1ahistone cluster 1, H1a0.011
Hk1hexokinase 10.011
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.011
Fgafibrinogen alpha chain0.010
LOC293989cytochrome P450-like0.010
Agtr1aangiotensin II receptor, type 1a0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism