The network for 'retina homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retina homeostasis

A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.

NameDescriptionProbabilityFunc Analog Organism
Ush1gUsher syndrome 1G homolog (human)1.000
Pcdh15protocadherin 151.000
Cdh23cadherin 23 (otocadherin)0.999
Grxcr1glutaredoxin, cysteine rich 10.999
Bbs4Bardet-Biedl syndrome 4 (human)0.998
Ush1cUsher syndrome 1C homolog (human)0.991
Myo15myosin XV0.971
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.960
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.918
Pou4f3POU domain, class 4, transcription factor 30.900
Ptprqprotein tyrosine phosphatase, receptor type, Q0.882
Myo7amyosin VIIA0.877
LOC100503041PDZ domain-containing protein 7-like0.867
Gpr98G protein-coupled receptor 980.843
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.837
Bbs2Bardet-Biedl syndrome 2 (human)0.753
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.709
Tmc1transmembrane channel-like gene family 10.692
Ift88intraflagellar transport 88 homolog (Chlamydomonas)0.656
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.646
Nr2e1nuclear receptor subfamily 2, group E, member 10.569
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.568
S1pr2sphingosine-1-phosphate receptor 20.463
Bbs1Bardet-Biedl syndrome 1 (human)0.455
Gfi1growth factor independent 10.405
Try10trypsin 100.361
Hsp90b1heat shock protein 90, beta (Grp94), member 10.256
Hspa5heat shock protein 50.197
Dclk1doublecortin-like kinase 10.195
Iqcb1IQ calmodulin-binding motif containing 10.194
Tmprss3transmembrane protease, serine 30.182
Slc26a4solute carrier family 26, member 40.175
Ift57intraflagellar transport 57 homolog (Chlamydomonas)0.175
Actbactin, beta0.168
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.168
Eef1a1eukaryotic translation elongation factor 1 alpha 10.163
Crb2crumbs homolog 2 (Drosophila)0.157
Hspa8heat shock protein 80.156
H2-K1histocompatibility 2, K1, K region0.152
Rdh8retinol dehydrogenase 80.149
Slc26a5solute carrier family 26, member 50.147
Gdf5growth differentiation factor 50.120
Mks1Meckel syndrome, type 10.119
Arr3arrestin 3, retinal0.111
Myo6myosin VI0.111
Arl6ADP-ribosylation factor-like 60.108
Npc1Niemann Pick type C10.098
Tuba1atubulin, alpha 1A0.097
Kif3akinesin family member 3A0.093
Apoeapolipoprotein E0.083
Pde6gphosphodiesterase 6G, cGMP-specific, rod, gamma0.079
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.073
Bbs9Bardet-Biedl syndrome 9 (human)0.068
Ppiapeptidylprolyl isomerase A0.065
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.063
Scn8asodium channel, voltage-gated, type VIII, alpha0.059
Lrp1low density lipoprotein receptor-related protein 10.058
MkksMcKusick-Kaufman syndrome protein0.055
Abcg1ATP-binding cassette, sub-family G (WHITE), member 10.049
Cacna1fcalcium channel, voltage-dependent, alpha 1F subunit0.048
Tuba1btubulin, alpha 1B0.048
Magt1magnesium transporter 10.047
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.047
Cd177CD177 antigen0.047
Prss1protease, serine, 1 (trypsin 1)0.046
Oc90otoconin 900.041
BC027072cDNA sequence BC0270720.041
Tcp11t-complex protein 110.040
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.040
Hspa9heat shock protein 90.040
Kif9kinesin family member 90.040
Crxcone-rod homeobox containing gene0.039
Ubxn11UBX domain protein 110.038
Gnat1guanine nucleotide binding protein, alpha transducing 10.037
Lig4ligase IV, DNA, ATP-dependent0.037
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.036
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.036
Ttc8tetratricopeptide repeat domain 80.036
Thrbthyroid hormone receptor beta0.036
Cps1carbamoyl-phosphate synthetase 10.035
Stt3aSTT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)0.035
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.034
Ppm1nprotein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)0.034
Emx1empty spiracles homolog 1 (Drosophila)0.032
Dbidiazepam binding inhibitor0.032
Tulp1tubby like protein 10.031
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.031
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.030
Clrn1clarin 10.030
Tmsb4xthymosin, beta 4, X chromosome0.029
Makmale germ cell-associated kinase0.029
Wdr78WD repeat domain 780.028
Aipl1aryl hydrocarbon receptor-interacting protein-like 10.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ift88intraflagellar transport 88 homolog0.972
cc2d2acoiled-coil and C2 domain containing 2A0.932
kif17kinesin family member 170.615
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.560
ptch1patched 10.477
dync1h1dynein, cytoplasmic 1, heavy chain 10.430
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.360
gc3guanylyl cyclase 30.355
synj1synaptojanin 10.273
ef1aelongation factor 1-alpha0.231
epb41l5erythrocyte membrane protein band 4.1 like 50.191
tp63tumor protein p630.187
traf3ip1TNF receptor-associated factor 3 interacting protein 10.179
apoebapolipoprotein Eb0.168
dctn1adynactin 1a0.144
restRE1-silencing transcription factor0.131
bbs2Bardet-Biedl syndrome 20.129
ift52intraflagellar transport protein 520.088
aanat2arylalkylamine N-acetyltransferase0.084
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.083
ush1cUsher syndrome 1C (autosomal recessive, severe)0.078
hspa5heat shock protein 50.077
ttc21btetratricopeptide repeat domain 21B0.075
arl13bADP-ribosylation factor-like 13b0.071
foxa2forkhead box A20.070
pcnaproliferating cell nuclear antigen0.067
pdzd7aPDZ domain containing 7a0.059
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.052
wnt9awingless-type MMTV integration site family, member 9A0.052
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.050
sox32SRY-box containing gene 320.049
col8a1acollagen, type VIII, alpha 1a0.049
cluap1clusterin associated protein 10.047
chaf1bchromatin assembly factor 1, subunit B0.047
scinlascinderin like a0.047
crxcone-rod homeobox0.046
mespamesoderm posterior a0.039
cbr1lcarbonyl reductase 1-like0.036
tbpl2TATA box binding protein like 20.036
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.036
mmp9matrix metalloproteinase 90.035
igf2ainsulin-like growth factor 2a0.035
lrrc6leucine rich repeat containing 60.034
hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.034
mespbmesoderm posterior b0.033
ift172intraflagellar transport 1720.032
manfmesencephalic astrocyte-derived neurotrophic factor0.030
bbs5Bardet-Biedl syndrome 50.029
eomesaeomesodermin homolog a0.028
ift57intraflagellar transport protein 570.028
hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.027
col11a1bcollagen type XI alpha-1b and collagen, type XI, alpha 1b0.027
rhoaaras homolog gene family, member Aa0.027
tbpTATA box binding protein0.027
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.027
tbx2bT-box 2b0.026
leprleptin receptor0.025
wnt10awingless-type MMTV integration site family, member 10a0.025
jag1bjagged 1b0.024
cldniclaudin i0.024
ca7carbonic anhydrase VII0.023
sox9aSRY-box containing gene 9a0.023
camk2g2calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 20.022
mtormechanistic target of rapamycin (serine/threonine kinase)0.022
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.021
piwil2piwi-like 2 (Drosophila)0.021
rhoabras homolog gene family, member Ab0.021
tagln2transgelin 20.021
cacnb2bcalcium channel, voltage-dependent, beta 2b0.020
atoh7atonal homolog 70.020
lhx6LIM homeobox 60.020
tsc22d3TSC22 domain family, member 30.020
kif3bkinesin family member 3B0.019
actr1ARP1 actin-related protein 1, centractin (yeast)0.019
hoxa13ahomeo box A13a0.019
arl6ADP-ribosylation factor-like 60.018
lrrc50leucine rich repeat containing 500.018
pitx3paired-like homeodomain transcription factor 30.018
gpr126G protein-coupled receptor 1260.018
xbp1X-box binding protein 10.018
tbx3T-box 30.018
bbs7Bardet-Biedl syndrome 70.017
mst1rbmacrophage stimulating 1 receptor (c-met-related tyrosine kinase), b0.017
ift46intraflagellar transport protein 460.016
ptch2patched 20.016
irf11interferon regulatory factor 110.016
stk11serine/threonine kinase 110.016
grk7aG-protein-coupled receptor kinase 7a0.016
twsg1btwisted gastrulation homolog 1b (Drosophila)0.016
hhiphedgehog interacting protein0.016
hsp90b1heat shock protein 90, beta (grp94), member 10.015
frzbfrizzled-related protein0.015
muskmuscle, skeletal, receptor tyrosine kinase0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
trptransient receptor potential0.138
ninaEneither inactivation nor afterpotential E0.132
LysDLysozyme D0.058
LysBLysozyme B0.051
LysELysozyme E0.047
LysCLysozyme C0.043
rdgCretinal degeneration C0.025
Pph13PvuII-PstI homology 130.021
Rh3Rhodopsin 30.018
GM130CG11061 gene product from transcript CG11061-RB0.018
CG9014CG9014 gene product from transcript CG9014-RA0.017
Vha100-1CG1709 gene product from transcript CG1709-RF0.017
Prosalpha1Proteasome alpha1 subunit0.016
Jon65AiiiJonah 65Aiii0.013
Arr1Arrestin 10.013
Arr2Arrestin 20.013
inaCinactivation no afterpotential C0.013
retinophilinCG10233 gene product from transcript CG10233-RA0.013
SnapSoluble NSF attachment protein0.012
CG17633CG17633 gene product from transcript CG17633-RA0.012
CG17108CG17108 gene product from transcript CG17108-RA0.011
CG6751CG6751 gene product from transcript CG6751-RA0.011
ninaCneither inactivation nor afterpotential C0.010
CG13792CG13792 gene product from transcript CG13792-RA0.010
ASPPAnkyrin-repeat, SH3-domain, and Proline-rich-region containing Protein0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HLA-Bmajor histocompatibility complex, class I, B1.000
HLA-Cmajor histocompatibility complex, class I, C0.997
HLA-Amajor histocompatibility complex, class I, A0.995
HLA-Gmajor histocompatibility complex, class I, G0.957
KRT14keratin 140.909
HLA-Fmajor histocompatibility complex, class I, F0.828
KRT17keratin 170.826
HLA-Emajor histocompatibility complex, class I, E0.822
BBS2Bardet-Biedl syndrome 20.793
HSPB8heat shock 22kDa protein 80.744
CRYABcrystallin, alpha B0.689
TP63tumor protein p630.603
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.498
CFL1cofilin 1 (non-muscle)0.450
TFF1trefoil factor 10.447
BAG3BCL2-associated athanogene 30.407
ACTBactin, beta0.332
KRT18keratin 180.325
KRT6Bkeratin 6B0.297
CTNND1catenin (cadherin-associated protein), delta 10.291
EXOC7exocyst complex component 70.280
USH1CUsher syndrome 1C (autosomal recessive, severe)0.259
HSPB7heat shock 27kDa protein family, member 7 (cardiovascular)0.209
KRT16keratin 160.193
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.188
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.188
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.187
ALDOBaldolase B, fructose-bisphosphate0.163
DSG2desmoglein 20.156
SPRR1Bsmall proline-rich protein 1B0.154
HSPB2heat shock 27kDa protein 20.153
KLK10kallikrein-related peptidase 100.151
KRT15keratin 150.145
FTLferritin, light polypeptide0.145
KRT9keratin 90.145
TRIM29tripartite motif containing 290.142
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.138
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.137
C19orf50chromosome 19 open reading frame 500.134
IFITM2interferon induced transmembrane protein 2 (1-8D)0.130
KRT5keratin 50.130
IGL@immunoglobulin lambda locus0.129
DISC1disrupted in schizophrenia 10.125
ENAHenabled homolog (Drosophila)0.114
HSPB1heat shock 27kDa protein 10.108
USHBP1Usher syndrome 1C binding protein 10.107
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.104
APOA1apolipoprotein A-I0.102
CFL2cofilin 2 (muscle)0.100
KRT6Akeratin 6A0.098
ACTG1actin, gamma 10.096
KRT6Ckeratin 6C0.092
KRT19keratin 190.086
SPRR1Asmall proline-rich protein 1A0.081
G3BP1GTPase activating protein (SH3 domain) binding protein 10.080
DSG3desmoglein 30.076
KRT1keratin 10.073
FTH1ferritin, heavy polypeptide 10.072
PARK7Parkinson disease (autosomal recessive, early onset) 70.068
KLK7kallikrein-related peptidase 70.067
KLK5kallikrein-related peptidase 50.066
IGK@immunoglobulin kappa locus0.066
KRT75keratin 750.063
IFITM3interferon induced transmembrane protein 3 (1-8U)0.060
USH1GUsher syndrome 1G (autosomal recessive)0.060
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.058
PDIA6protein disulfide isomerase family A, member 60.058
MEOX2mesenchyme homeobox 20.057
MAP3K7mitogen-activated protein kinase kinase kinase 70.056
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.053
TBXA2Rthromboxane A2 receptor0.053
PLD3phospholipase D family, member 30.053
GABRPgamma-aminobutyric acid (GABA) A receptor, pi0.052
KRT4keratin 40.052
CEP290centrosomal protein 290kDa0.050
NPC2Niemann-Pick disease, type C20.047
DSG1desmoglein 10.046
CLIP1CAP-GLY domain containing linker protein 10.045
ALOX12arachidonate 12-lipoxygenase0.045
CRYBB2crystallin, beta B20.045
KLK3kallikrein-related peptidase 30.045
LY6Dlymphocyte antigen 6 complex, locus D0.044
KRT34keratin 340.044
ACTC1actin, alpha, cardiac muscle 10.044
MAFIPMAFF interacting protein0.042
CFDcomplement factor D (adipsin)0.042
PI3peptidase inhibitor 3, skin-derived0.041
GJB3gap junction protein, beta 3, 31kDa0.041
FOXI1forkhead box I10.040
RHCGRh family, C glycoprotein0.040
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism