The network for 'macromolecule localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecule localization

Any process in which a macromolecule is transported to, or maintained in, a specific location.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.369
mig-5Protein MIG-50.360
atn-1Protein ATN-10.341
vab-3Protein VAB-30.333
egl-18Protein EGL-180.315
chc-1Protein CHC-10.312
unc-83Protein UNC-830.308
nhr-45Protein NHR-450.307
D1081.8Protein D1081.80.296
ubq-1Protein UBQ-10.285
rpl-4Protein RPL-40.284
unc-112Protein UNC-1120.282
unc-104Protein UNC-1040.279
rskn-2Protein RSKN-20.261
acy-1Protein ACY-10.259
abt-4Protein ABT-40.258
nphp-4Protein NPHP-40.256
unc-52Protein UNC-520.256
egl-8Protein EGL-80.256
vha-8Protein VHA-80.253
egl-44Protein EGL-440.249
sma-6Protein SMA-60.247
viln-1Protein VILN-10.233
prg-1Protein PRG-10.233
mut-16Protein MUT-160.230
sar-1Protein SAR-10.230
pat-3Protein PAT-30.229
xpo-2Protein XPO-20.227
plc-3Protein PLC-30.226
bli-4Protein BLI-40.226
sad-1Protein SAD-10.226
egl-46Protein EGL-460.226
npp-7Protein NPP-70.224
glt-1Protein GLT-10.224
ptr-14Protein PTR-140.223
F08B12.1Protein F08B12.10.222
T27A3.1Protein T27A3.10.221
col-157Protein COL-1570.221
gld-1Protein GLD-10.220
C05D11.7Protein C05D11.70.218
sqt-1Protein SQT-10.218
unc-6Protein UNC-60.217
nstp-2Protein NSTP-20.217
R166.2Protein R166.20.216
dnc-2Protein DNC-20.216
epg-4Protein EPG-40.215
ima-2Protein IMA-20.214
his-64Protein HIS-640.212
sams-1Protein SAMS-10.212
mua-6Protein MUA-60.212
pes-7Protein PES-70.210
pas-2Protein PAS-20.210
hpo-28Protein HPO-280.209
C46C11.3Protein C46C11.30.207
sma-9Protein SMA-90.206
ZC449.5Protein ZC449.50.206
scd-1Protein SCD-10.205
lin-36Protein LIN-360.205
osm-5Protein OSM-50.204
egl-21Protein EGL-210.204
plc-1Protein PLC-10.204
F19B6.1Protein F19B6.10.201
unc-9Protein UNC-90.201
pkg-1Protein PKG-10.201
sem-4Protein SEM-40.201
elt-6Protein ELT-60.200
lag-1Protein LAG-10.198
che-2Protein CHE-20.198
mtm-3Protein MTM-30.197
sas-4Protein SAS-40.197
C10E2.6Protein C10E2.60.197
glo-4Protein GLO-40.197
lbp-2Protein LBP-20.197
zyg-8Protein ZYG-80.197
skr-2Protein SKR-20.197
F57B10.4Protein F57B10.40.196
abl-1Protein ABL-10.196
set-1Protein SET-10.196
unc-10Protein UNC-100.196
C16D9.4Protein C16D9.40.195
cyk-4Protein CYK-40.195
mig-2Protein MIG-20.195
egal-1Protein EGAL-10.194
npp-1Protein NPP-10.193
tol-1Protein TOL-10.193
mcm-5Protein MCM-50.193
col-117Protein COL-1170.193
pmk-3Protein PMK-30.193
B0495.8Protein B0495.80.193
Y54E5A.7Protein Y54E5A.70.193
npp-19Protein NPP-190.192
hlh-1Protein HLH-10.192
col-180Protein COL-1800.192
camt-1Protein CAMT-10.192
mat-3Protein MAT-30.191
R90.1Protein R90.10.191
let-268Protein LET-2680.191
cul-2Protein CUL-20.191
egg-6Protein EGG-60.190
chd-7Protein CHD-70.190
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pkd2polycystic kidney disease 20.788
sox3SRY-box containing gene 30.595
nanos3nanos homolog 30.337
raraaretinoic acid receptor, alpha a0.327
alcambactivated leukocyte cell adhesion molecule b0.311
tpm4tropomyosin 40.289
gpiaglucose phosphate isomerase a0.255
cnn2calponin 20.247
arnt2aryl hydrocarbon receptor nuclear translocator 20.227
flot2aflotillin 2a0.220
rpl13aribosomal protein L13a0.208
wnt4awingless-type MMTV integration site family, member 4a0.192
cx39.9connexin 39.90.184
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.178
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.175
anxa1aannexin A1a0.175
rab1aRAB1A, member RAS oncogene family0.175
shhasonic hedgehog a0.173
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.162
lef1lymphocyte enhancer binding factor 10.152
trim3atripartite motif-containing 3a0.147
cdh1cadherin 1, epithelial0.146
arpc5aactin related protein 2/3 complex, subunit 5A0.142
col8a1acollagen, type VIII, alpha 1a0.140
egr1early growth response 10.138
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.138
dlg1discs, large (Drosophila) homolog 10.138
strapserine/threonine kinase receptor associated protein0.134
fezf2FEZ family zinc finger 20.134
mibmind bomb0.133
fgfr1afibroblast growth factor receptor 1a0.130
ccnb1cyclin B10.124
oprm1opioid receptor, mu 10.123
ccm2cerebral cavernous malformation 20.121
prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.120
efnb2aephrin B2a0.119
psen1presenilin 10.119
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.118
s1pr2sphingosine-1-phosphate receptor 20.118
wnt11rwingless-type MMTV integration site family, member 11, related0.118
has2hyaluronan synthase 20.118
wlswntless homolog (Drosophila)0.117
per2period homolog 2 (Drosophila)0.115
ef1aelongation factor 1-alpha0.114
pacsin3protein kinase C and casein kinase substrate in neurons 30.112
sec23aSec23 homolog A (S. cerevisiae)0.110
dag1dystroglycan 10.108
fhlafour and a half LIM domains a0.105
nkx2.2aNK2 transcription factor related 2a0.104
tfectranscription factor EC0.102
sept2septin 20.101
plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.101
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.101
ssrp1astructure specific recognition protein 1a0.100
wnt11wingless-type MMTV integration site family, member 110.099
gapdhglyceraldehyde-3-phosphate dehydrogenase0.099
grhl2bgrainyhead-like 2b (Drosophila)0.098
eif3haeukaryotic translation initiation factor 3, subunit H, a0.098
pobpartial optokinetic response b0.097
mef2amyocyte enhancer factor 2a0.096
ppargperoxisome proliferator activated receptor gamma0.095
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.094
copacoatomer protein complex, subunit alpha0.094
acvr1bactivin A receptor, type IB0.093
fgf3fibroblast growth factor 30.092
ube2naubiquitin-conjugating enzyme E2Na0.091
rarabretinoic acid receptor, alpha b0.090
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.090
fzd7bfrizzled homolog 7b0.089
ywhag13-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 10.089
atp6v1b2ATPase, H+ transporting, lysosomal V1 subunit B20.088
chd7chromodomain helicase DNA binding protein 70.087
prrc1proline-rich coiled-coil 10.086
pax7apaired box gene 7a0.086
cct7chaperonin containing TCP1, subunit 7 (eta)0.086
traf4atnf receptor-associated factor 4a0.085
pabpc1apoly A binding protein, cytoplasmic 1 a0.085
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.085
esr2bestrogen receptor 2b0.084
rag1recombination activating gene 10.084
yap1Yes-associated protein 10.083
igf1insulin-like growth factor 10.082
elk4ELK4, ETS-domain protein0.082
axin1axin 10.081
nup50nucleoporin 500.080
satb2SATB homeobox 20.080
ptbp1apolypyrimidine tract binding protein 1a0.080
pbx4pre-B-cell leukemia transcription factor 40.080
adcyap1aadenylate cyclase activating polypeptide 1a0.078
ptmaaprothymosin, alpha a0.078
krt4keratin 40.077
slit3slit (Drosophila) homolog 30.077
ncor1nuclear receptor co-repressor 10.076
st3gal2lST3 beta-galactoside alpha-2,3-sialyltransferase 2, like0.076
wnt10awingless-type MMTV integration site family, member 10a0.076
atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.076
notch2notch homolog 20.076
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pfn1profilin 10.906
Dnm1ldynamin 1-like0.796
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.709
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.662
Gria2glutamate receptor, ionotropic, AMPA 20.657
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.651
Dlgap3discs, large (Drosophila) homolog-associated protein 30.638
Stip1stress-induced phosphoprotein 10.634
Dynll1dynein light chain LC8-type 10.634
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.623
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.581
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.561
Hsph1heat shock 105/110 protein 10.560
Snap25synaptosomal-associated protein 250.542
Cd44Cd44 molecule0.516
Stx1asyntaxin 1A (brain)0.497
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.495
Ppp2r2cprotein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform0.494
Rab6aRAB6A, member RAS oncogene family0.492
Actbactin, beta0.475
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.475
RragaRas-related GTP binding A0.470
Syt4synaptotagmin IV0.467
Arpc1bactin related protein 2/3 complex, subunit 1B0.455
Syngr2synaptogyrin 20.454
Stx12syntaxin 120.451
Dlg1discs, large homolog 1 (Drosophila)0.443
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.434
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.430
Cd36CD36 molecule (thrombospondin receptor)0.429
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.427
Actr3ARP3 actin-related protein 3 homolog (yeast)0.425
Arf1ADP-ribosylation factor 10.424
Wisp1WNT1 inducible signaling pathway protein 10.409
OgtO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.408
Rhobras homolog gene family, member B0.403
Lmnalamin A0.399
Ppp3cbprotein phosphatase 3, catalytic subunit, beta isoform0.398
Nrxn1neurexin 10.395
Stat6signal transducer and activator of transcription 60.392
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.378
Nfianuclear factor I/A0.377
Timp3TIMP metallopeptidase inhibitor 30.373
Ptprcprotein tyrosine phosphatase, receptor type, C0.371
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.369
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.365
Cbscystathionine beta synthase0.364
Myl6lmyosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like0.358
Rhoaras homolog gene family, member A0.357
Kif1bkinesin family member 1B0.356
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.356
Itpr2inositol 1,4,5-triphosphate receptor, type 20.346
Prrx1paired related homeobox 10.343
Jak1Janus kinase 10.342
Myadmmyeloid-associated differentiation marker0.340
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.335
Pmfbp1polyamine modulated factor 1 binding protein 10.334
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.329
Syn1synapsin I0.327
Pdk4pyruvate dehydrogenase kinase, isozyme 40.325
Ccl4chemokine (C-C motif) ligand 40.318
Tnftumor necrosis factor (TNF superfamily, member 2)0.317
S1pr2sphingosine-1-phosphate receptor 20.316
Wdr1WD repeat domain 10.315
Accn2amiloride-sensitive cation channel 2, neuronal0.314
Tpm3tropomyosin 3, gamma0.312
WaslWiskott-Aldrich syndrome-like0.306
Ptafrplatelet-activating factor receptor0.299
Anxa2annexin A20.298
Bglapbone gamma-carboxyglutamate (gla) protein0.294
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.291
Ideinsulin degrading enzyme0.289
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.286
Myo1cmyosin IC0.283
Mpeg1macrophage expressed 10.283
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.282
Vps35vacuolar protein sorting 35 homolog (S. cerevisiae)0.279
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.277
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.277
Nlrp6NLR family, pyrin domain containing 60.276
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.270
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.270
Rap1bRAP1B, member of RAS oncogene family0.268
Ptger2prostaglandin E receptor 2 (subtype EP2)0.268
Rab7aRAB7A, member RAS oncogene family0.267
Picalmphosphatidylinositol binding clathrin assembly protein0.265
RGD1560925similar to 2610034M16Rik protein0.265
Casp12caspase 120.265
Eif4heukaryotic translation initiation factor 4H0.263
Mapk1mitogen activated protein kinase 10.259
Ccr5chemokine (C-C motif) receptor 50.257
Nrasneuroblastoma ras oncogene0.252
Ccl2chemokine (C-C motif) ligand 20.252
Grip1glutamate receptor interacting protein 10.251
Il1ainterleukin 1 alpha0.250
Wdfy1WD repeat and FYVE domain containing 10.250
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism