The network for 'intestinal absorption' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intestinal absorption

Any process in which nutrients are taken up from the contents of the intestine.

NameDescriptionProbabilityFunc Analog Organism
Ppargperoxisome proliferator activated receptor gamma0.999
Apoeapolipoprotein E0.995
Leprleptin receptor0.995
Nos3nitric oxide synthase 3, endothelial cell0.976
Apoa1apolipoprotein A-I0.770
Abcg5ATP-binding cassette, sub-family G (WHITE), member 50.695
Lrp1low density lipoprotein receptor-related protein 10.552
Cav1caveolin 1, caveolae protein0.537
Plin1perilipin 10.486
Rxraretinoid X receptor alpha0.466
Cftrcystic fibrosis transmembrane conductance regulator homolog0.432
Nos1nitric oxide synthase 1, neuronal0.392
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.324
Pnpla2patatin-like phospholipase domain containing 20.316
Gata4GATA binding protein 40.309
Esr1estrogen receptor 1 (alpha)0.255
S100a10S100 calcium binding protein A10 (calpactin)0.227
Lyz2lysozyme 20.224
Ghrgrowth hormone receptor0.217
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.214
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.204
Slc7a9solute carrier family 7 (cationic amino acid transporter, y+ system), member 90.149
Apobapolipoprotein B0.137
Hnf4ahepatic nuclear factor 4, alpha0.129
Ldlrlow density lipoprotein receptor0.128
Scd1stearoyl-Coenzyme A desaturase 10.124
Apoa4apolipoprotein A-IV0.119
Otcornithine transcarbamylase0.117
Insrinsulin receptor0.112
Pparaperoxisome proliferator activated receptor alpha0.111
St14suppression of tumorigenicity 14 (colon carcinoma)0.109
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.108
Aldobaldolase B, fructose-bisphosphate0.107
Abcg8ATP-binding cassette, sub-family G (WHITE), member 80.104
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.103
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.098
Clrn3clarin 30.095
Slc12a1solute carrier family 12, member 10.093
Npc1Niemann Pick type C10.088
Nr1i2nuclear receptor subfamily 1, group I, member 20.088
Lpin1lipin 10.088
Slc4a4solute carrier family 4 (anion exchanger), member 40.085
Ptenphosphatase and tensin homolog0.084
Slc4a11solute carrier family 4, sodium bicarbonate transporter-like, member 110.083
Nr1i3nuclear receptor subfamily 1, group I, member 30.076
Vegfavascular endothelial growth factor A0.074
Spp2secreted phosphoprotein 20.072
Mep1bmeprin 1 beta0.071
Nr0b2nuclear receptor subfamily 0, group B, member 20.071
Cdhr5cadherin-related family member 50.070
Cideccell death-inducing DFFA-like effector c0.068
Apoc3apolipoprotein C-III0.068
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.067
Nos2nitric oxide synthase 2, inducible0.063
Trp53transformation related protein 530.063
S100a6S100 calcium binding protein A6 (calcyclin)0.061
Nfe2l2nuclear factor, erythroid derived 2, like 20.060
Agtr1aangiotensin II receptor, type 1a0.059
Cd36CD36 antigen0.058
Ptgs2prostaglandin-endoperoxide synthase 20.057
Tgfb1transforming growth factor, beta 10.056
Cd44CD44 antigen0.055
Acot12acyl-CoA thioesterase 120.054
Ptpn11protein tyrosine phosphatase, non-receptor type 110.053
Abhd5abhydrolase domain containing 50.053
Prap1proline-rich acidic protein 10.053
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.050
Slc4a1solute carrier family 4 (anion exchanger), member 10.050
Fbxl5F-box and leucine-rich repeat protein 50.050
Slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.049
Gucy2cguanylate cyclase 2c0.048
Nr1h4nuclear receptor subfamily 1, group H, member 40.047
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.043
Lifleukemia inhibitory factor0.042
Zg16zymogen granule protein 160.041
Vdrvitamin D receptor0.040
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.040
Sult1b1sulfotransferase family 1B, member 10.040
Vil1villin 10.039
Lipelipase, hormone sensitive0.039
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.038
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.038
Gata1GATA binding protein 10.038
Guca2bguanylate cyclase activator 2b (retina)0.038
Rdh16retinol dehydrogenase 160.038
Hnf4ghepatocyte nuclear factor 4, gamma0.037
Hgdhomogentisate 1, 2-dioxygenase0.037
Thrbthyroid hormone receptor beta0.036
Pklrpyruvate kinase liver and red blood cell0.036
Spink4serine peptidase inhibitor, Kazal type 40.036
Mmp9matrix metallopeptidase 90.035
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.034
Irs2insulin receptor substrate 20.034
Ins2insulin II0.033
Gcgroup specific component0.033
Golt1agolgi transport 1 homolog A (S. cerevisiae)0.033
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
anxa2aannexin A2a0.999
anxa1aannexin A1a0.999
krt4keratin 40.968
capns1acalpain, small subunit 1 a0.849
anxa1bannexin A1b0.723
fabp1b.1fatty acid binding protein 1b, tandem duplicate 10.716
apoa4apolipoprotein A-IV0.685
hbaa1hemoglobin alpha adult-10.674
fabp2fatty acid binding protein 2, intestinal0.586
capns1bcalpain, small subunit 1 b0.500
sepp1bselenoprotein P, plasma, 1b0.495
aco1aconitase 1, soluble0.425
ireb2iron-responsive element binding protein 20.378
anxa6annexin A60.362
apoblapolipoprotein B, like0.340
pck2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.316
pkp1plakophilin 10.286
pla2g12bphospholipase A2, group XIIB0.282
tagln2transgelin 20.282
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.260
apobapolipoprotein B0.254
apoa1apolipoprotein A-I0.250
s100a10bS100 calcium binding protein A10b0.224
anxa11aannexin A11a0.217
hnf4ahepatocyte nuclear factor 4, alpha0.201
pvalb9parvalbumin 90.182
perpPERP, TP53 apoptosis effector0.160
s100v2S100 calcium binding protein V20.153
col6a2collagen, type VI, alpha 20.151
slc27a2solute carrier family 27 (fatty acid transporter), member 20.138
anxa11bannexin A11b0.137
col19a1collagen, type XIX, alpha 10.137
anxa5bannexin A5b0.131
apoeaapolipoprotein Ea0.128
fevFEV (ETS oncogene family)0.127
uroduroporphyrinogen decarboxylase0.116
rbp2aretinol binding protein 2a, cellular0.110
zmat2zinc finger, matrin type 20.100
tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.090
mmp2matrix metalloproteinase 20.085
krt5keratin 50.084
pdzk1PDZ domain containing 10.082
cd63Cd63 antigen0.082
lgals3llectin, galactoside-binding, soluble, 3 (galectin 3)-like0.079
tpm3tropomyosin 30.077
tm4sf4transmembrane 4 L six family member 40.076
ctskcathepsin K0.076
snx5sorting nexin 50.074
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.069
capn9calpain 90.066
ptgs2aprostaglandin-endoperoxide synthase 2a0.066
stat3signal transduction and activation of transcription 30.065
fgbfibrinogen, B beta polypeptide0.064
hbbe1.1hemoglobin beta embryonic-1.10.061
acsl5acyl-CoA synthetase long-chain family member 50.059
sdprbserum deprivation response b0.059
timp2atissue inhibitor of metalloproteinase 2a0.058
b3gnt5aUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a0.057
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.056
aldobaldolase b, fructose-bisphosphate0.053
gsnbgelsolin b0.053
fbp1bfructose-1,6-bisphosphatase 1b0.053
aqp1a.1aquaporin 1a, tandem duplicate 10.052
slc26a1solute carrier family 26 (sulfate transporter), member 10.048
LOC569128hypothetical protein LOC5691280.047
tfectranscription factor EC0.047
cfl1cofilin 1 (non-muscle)0.046
tefthyrotroph embryonic factor0.045
gabarapaGABA(A) receptor-associated protein a0.044
kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.043
hbbe3hemoglobin beta embryonic-30.043
itih2inter-alpha (globulin) inhibitor H20.041
slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.041
nr0b2anuclear receptor subfamily 0, group B, member 2a0.041
zmynd11zinc finger, MYND domain containing 110.038
emilin1belastin microfibril interfacer 1b0.037
elovl1belongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b0.037
pgam2phosphoglycerate mutase 2 (muscle)0.037
hspb12heat shock protein, alpha-crystallin-related, b120.036
gmppbGDP-mannose pyrophosphorylase B0.036
gstalglutathione S-transferase, alpha-like0.035
gapdhglyceraldehyde-3-phosphate dehydrogenase0.033
foxi3aforkhead box I3a0.033
sult1st3sulfotransferase family 1, cytosolic sulfotransferase 30.032
gata5GATA-binding protein 50.031
col6a1collagen, type VI, alpha 10.031
cldncclaudin c0.031
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ABCG5ATP-binding cassette, sub-family G (WHITE), member 50.608
ABCG8ATP-binding cassette, sub-family G (WHITE), member 80.512
S100A10S100 calcium binding protein A100.206
CAV2caveolin 20.179
RXRAretinoid X receptor, alpha0.154
APOC3apolipoprotein C-III0.115
HRhairless homolog (mouse)0.083
EGFRepidermal growth factor receptor0.077
NCOA1nuclear receptor coactivator 10.072
PCSK9proprotein convertase subtilisin/kexin type 90.040
PRKCDBPprotein kinase C, delta binding protein0.039
MED25mediator complex subunit 250.034
ANXA1annexin A10.034
LCATlecithin-cholesterol acyltransferase0.033
SEC61GSec61 gamma subunit0.030
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.029
RUNX1runt-related transcription factor 10.027
RARAretinoic acid receptor, alpha0.027
SQLEsqualene epoxidase0.027
DMC1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.026
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.025
NCOA6nuclear receptor coactivator 60.024
PTENphosphatase and tensin homolog0.021
APOEapolipoprotein E0.019
PTPRFprotein tyrosine phosphatase, receptor type, F0.019
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.018
APOC1apolipoprotein C-I0.018
F2Rcoagulation factor II (thrombin) receptor0.017
TMSB10thymosin beta 100.017
AHNAKAHNAK nucleoprotein0.017
DHCR77-dehydrocholesterol reductase0.016
FGAfibrinogen alpha chain0.015
FOXO1forkhead box O10.015
TXNRD1thioredoxin reductase 10.014
PDIA3protein disulfide isomerase family A, member 30.013
APOA2apolipoprotein A-II0.013
TXNDC2thioredoxin domain containing 2 (spermatozoa)0.012
CTSBcathepsin B0.012
UFD1Lubiquitin fusion degradation 1 like (yeast)0.011
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.011
UBL5ubiquitin-like 50.011
LGALS3lectin, galactoside-binding, soluble, 30.011
APOA4apolipoprotein A-IV0.011
BRCA2breast cancer 2, early onset0.011
APOBapolipoprotein B (including Ag(x) antigen)0.010
PGFplacental growth factor0.010
ANXA5annexin A50.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.489
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.436
Prlrprolactin receptor0.240
Ltb4rleukotriene B4 receptor0.150
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.137
Spink1serine peptidase inhibitor, Kazal type 10.123
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.113
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.107
Tff3trefoil factor 3, intestinal0.087
Aqp7aquaporin 70.082
Nlrp6NLR family, pyrin domain containing 60.070
Acox2acyl-Coenzyme A oxidase 2, branched chain0.069
Krt20keratin 200.068
Aadacarylacetamide deacetylase (esterase)0.063
Upk3bluroplakin 3B-like0.060
Otcornithine carbamoyltransferase0.059
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.057
Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 10.057
Stra6stimulated by retinoic acid gene 60.052
Shhsonic hedgehog0.052
Amnamnionless homolog (mouse)0.052
Fabp1fatty acid binding protein 1, liver0.051
Hnf4ahepatocyte nuclear factor 4, alpha0.050
Ces1ecarboxylesterase 1E0.049
Impg1interphotoreceptor matrix proteoglycan 10.046
Tmigd1transmembrane and immunoglobulin domain containing 10.046
Abcg5ATP-binding cassette, subfamily G (WHITE), member 50.044
Dakdihydroxyacetone kinase 2 homolog (S. cerevisiae)0.042
Sec14l2SEC14-like 2 (S. cerevisiae)0.039
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.038
Rup2urinary protein 20.037
Vipr1vasoactive intestinal peptide receptor 10.037
Gjb1gap junction protein, beta 10.036
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.035
Acot12acyl-CoA thioesterase 120.035
Igsf1immunoglobulin superfamily, member 10.034
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.034
Mosc1MOCO sulphurase C-terminal domain containing 10.033
Ust5rintegral membrane transport protein UST5r0.032
Ccl11chemokine (C-C motif) ligand 110.032
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.032
Ifna1interferon-alpha 10.032
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.031
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.031
Apobapolipoprotein B0.031
Tsxtestis specific X-linked gene0.031
Clca4chloride channel accessory 40.031
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.031
Slco1a1solute carrier organic anion transporter family, member 1a10.031
Flt4fms-related tyrosine kinase 40.030
Ntn1netrin 10.030
Fgf1fibroblast growth factor 10.030
Defa7defensin alpha 70.029
Btbd17BTB (POZ) domain containing 170.029
Foxc1forkhead box C10.029
Cfdcomplement factor D (adipsin)0.029
Asgr2asialoglycoprotein receptor 20.029
Klks3kallikrein, submaxillary gland S30.029
Svs6seminal vesicle secretory protein 60.028
Wnt6wingless-type MMTV integration site family, member 60.028
Prl8a7prolactin family 8, subfamily a, member 70.027
UST4rintegral membrane transport protein UST4r0.027
Cideacell death-inducing DFFA-like effector a0.026
Chst3carbohydrate (chondroitin 6) sulfotransferase 30.026
Slc15a1solute carrier family 15 (oligopeptide transporter), member 10.026
Krt5keratin 50.025
Clrn3clarin 30.025
Nphs1nephrosis 1 homolog (human)0.024
Slc22a7solute carrier family 22 (organic anion transporter), member 70.024
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.024
Grb7growth factor receptor bound protein 70.024
Trib1tribbles homolog 1 (Drosophila)0.024
Thrspthyroid hormone responsive0.024
Il22ra2interleukin 22 receptor, alpha 20.024
Pate4prostate and testis expressed 40.024
Lama3laminin, alpha 30.023
Btnl7butyrophilin-like 70.023
Acot1acyl-CoA thioesterase 10.023
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.023
Pemtphosphatidylethanolamine N-methyltransferase0.023
Bmp7bone morphogenetic protein 70.023
Sostdc1sclerostin domain containing 10.022
Prl8a2prolactin family 8, subfamily a, member 20.022
Fabp6fatty acid binding protein 6, ileal0.021
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.021
Dmgdhdimethylglycine dehydrogenase0.021
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.021
Tpothyroid peroxidase0.020
Hao2hydroxyacid oxidase 2 (long chain)0.020
Slco1a4solute carrier organic anion transporter family, member 1a40.020
RGD1564878similar to natural killer cell protease 70.020
Cryba4crystallin, beta A40.020
C3ar1complement component 3a receptor 10.020
Spink8serine peptidase inhibitor, Kazal type 80.020
Mcpt9mast cell protease 90.020
Mogmyelin oligodendrocyte glycoprotein0.019
Grifingalectin-related inter-fiber protein0.019
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism