The network for 'regulation of dna methylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dna methylation

Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

NameDescriptionProbabilityFunc Analog Organism
Trim24tripartite motif-containing 240.839
Ezh2enhancer of zeste homolog 2 (Drosophila)0.690
Dnmt3aDNA methyltransferase 3A0.640
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.555
Dnmt3bDNA methyltransferase 3B0.524
Kdm2blysine (K)-specific demethylase 2B0.475
Ncoa3nuclear receptor coactivator 30.475
Pou5f1POU domain, class 5, transcription factor 10.363
Dnmt3lDNA (cytosine-5-)-methyltransferase 3-like0.317
Apcadenomatosis polyposis coli0.293
Zfp760zinc finger protein 7600.286
Cd40CD40 antigen0.274
Trp53transformation related protein 530.271
Ighimmunoglobulin heavy chain complex0.215
RybpRING1 and YY1 binding protein0.182
Ptgs2prostaglandin-endoperoxide synthase 20.171
Hellshelicase, lymphoid specific0.166
Brca2breast cancer 20.158
A530054K11RikRIKEN cDNA A530054K11 gene0.156
Runx1runt related transcription factor 10.146
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.134
Hdac1histone deacetylase 10.124
Ergavian erythroblastosis virus E-26 (v-ets) oncogene related0.116
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.115
Zfp748zinc finger protein 7480.106
Zfp58zinc finger protein 580.099
Rsl1regulator of sex limited protein 10.095
Zfp759zinc finger protein 7590.094
NanogNanog homeobox0.094
Cbx1chromobox homolog 1 (Drosophila HP1 beta)0.091
Zfp455zinc finger protein 4550.087
Rnf2ring finger protein 20.087
Chaf1achromatin assembly factor 1, subunit A (p150)0.086
Ctnnb1catenin (cadherin associated protein), beta 10.080
Zfp418zinc finger protein 4180.078
Zfp709zinc finger protein 7090.077
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.074
Zfp229zinc finger protein0.073
Cbx3chromobox homolog 3 (Drosophila HP1 gamma)0.071
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.070
Csnk2a1casein kinase 2, alpha 1 polypeptide0.070
Zfp874bzinc finger protein 874b0.070
2610044O15RikRIKEN cDNA 2610044O15 gene0.068
Pik3r3phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)0.067
Axin1axin 10.063
Bcl6B-cell leukemia/lymphoma 60.058
Zfp317zinc finger protein 3170.057
Zfp429zinc finger protein 4290.057
Zfp790zinc finger protein 7900.055
Gsk3bglycogen synthase kinase 3 beta0.053
Stmn1stathmin 10.051
Cxcr4chemokine (C-X-C motif) receptor 40.050
Gm5595predicted gene 55950.049
Kbtbd7kelch repeat and BTB (POZ) domain containing 70.048
Zfp738zinc finger protein 7380.047
Zfp708zinc finger protein 7080.047
Zfp595zinc finger protein 5950.046
BlnkB-cell linker0.043
BtkBruton agammaglobulinemia tyrosine kinase0.042
Pik3cbphosphatidylinositol 3-kinase, catalytic, beta polypeptide0.040
Zfp87zinc finger protein 870.040
AI987944expressed sequence AI9879440.038
BrafBraf transforming gene0.038
Sufusuppressor of fused homolog (Drosophila)0.038
2610008E11RikRIKEN cDNA 2610008E11 gene0.036
Sin3atranscriptional regulator, SIN3A (yeast)0.035
Tnfsf15tumor necrosis factor (ligand) superfamily, member 150.035
D030056L22RikRIKEN cDNA D030056L22 gene0.035
Atrataxia telangiectasia and Rad3 related0.035
Zfp846zinc finger protein 8460.033
Arid4aAT rich interactive domain 4A (RBP1-like)0.030
Zfp952zinc finger protein 9520.029
Zfp273zinc finger protein 2730.028
Zfp39zinc finger protein 390.027
Zfp677zinc finger protein 6770.027
Fpgtfucose-1-phosphate guanylyltransferase0.026
Zfp74zinc finger protein 740.026
MgaMAX gene associated0.025
Ppwd1peptidylprolyl isomerase domain and WD repeat containing 10.024
Zfp953zinc finger protein 9530.024
Asb13ankyrin repeat and SOCS box-containing 130.024
Zfp329zinc finger protein 3290.024
Senp8SUMO/sentrin specific peptidase 80.024
Ccnd1cyclin D10.024
Rbbp9retinoblastoma binding protein 90.023
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.023
AI597479expressed sequence AI5974790.023
Zfp84zinc finger protein 840.023
Tstd2thiosulfate sulfurtransferase (rhodanese)-like domain containing 20.023
Zfp667zinc finger protein 6670.023
Hist1h3ghistone cluster 1, H3g0.022
Dnmt1DNA methyltransferase (cytosine-5) 10.022
2810422O20RikRIKEN cDNA 2810422O20 gene0.021
Zbtb33zinc finger and BTB domain containing 330.021
Htthuntingtin0.021
Gm5141predicted gene 51410.020
Lig4ligase IV, DNA, ATP-dependent0.020
BcorBCL6 interacting corepressor0.020
Fam82bfamily with sequence similarity 82, member B0.020
Dckdeoxycytidine kinase0.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mpxmyeloid-specific peroxidase0.227
lcp1lymphocyte cytosolic plastin 10.206
lyzlysozyme0.134
oepone-eyed pinhead0.101
lmnb1lamin B10.084
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.061
nanos3nanos homolog 30.042
prlprolactin0.038
whsc1Wolf-Hirschhorn syndrome candidate 10.035
ndr1nodal-related 10.034
coro1acoronin, actin binding protein, 1A0.034
irx3biroquois homeobox protein 3b0.032
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.032
mmp9matrix metalloproteinase 90.030
foxn4forkhead box N40.029
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.029
mmp13amatrix metalloproteinase 13a0.027
ikzf1IKAROS family zinc finger 1 (Ikaros)0.026
otpborthopedia homolog b0.024
nkx2.2aNK2 transcription factor related 2a0.024
usp1ubiquitin specific protease 10.023
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.022
ssbp3bsingle stranded DNA binding protein 3b0.022
hnf1baHNF1 homeobox Ba0.021
hbae1hemoglobin alpha embryonic-10.021
pou3f3bPOU class 3 homeobox 3b0.021
pomcaproopiomelanocortin a0.020
nr2f2nuclear receptor subfamily 2, group F, member 20.020
marcksbmyristoylated alanine rich protein kinase C substrate b0.020
nkx2.1aNK2 homeobox 1a0.020
rfc1replication factor C (activator 1) 10.019
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.019
pola1polymerase (DNA directed), alpha 10.019
mosv-mos Moloney murine sarcoma viral oncogene homolog0.018
siah2lseven in absentia homolog 2 (Drosophila)-like0.018
gata2aGATA-binding protein 2a0.018
lhx3LIM homeobox 30.018
mtpmicrosomal triglyceride transfer protein0.018
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.018
pou3f2POU class 3 homeobox 20.018
drd2ldopamine receptor D2 like0.017
LOC567638hypothetical LOC5676380.016
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.016
nr2f1anuclear receptor subfamily 2, group F, member 1a0.016
atad5aATPase family, AAA domain containing 5a0.016
drldraculin0.016
ascl1aachaete-scute complex-like 1a (Drosophila)0.016
chaf1bchromatin assembly factor 1, subunit B0.016
aldobaldolase b, fructose-bisphosphate0.015
tyrtyrosinase0.015
pax6apaired box gene 6a0.014
ckap5cytoskeleton associated protein 50.014
scube2signal peptide, CUB domain, EGF-like 20.014
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.014
sass6spindle assembly 6 homolog (C. elegans)0.013
eomesaeomesodermin homolog a0.013
ptproprotein tyrosine phosphatase, receptor type, O0.013
olig4oligodendrocyte transcription factor 40.013
tshbthyroid stimulating hormone, beta subunit0.013
sephs1selenophosphate synthetase 10.013
cbx1achromobox homolog 1a (HP1 beta homolog Drosophila)0.013
ncf1neutrophil cytosolic factor 10.012
rif1RAP1 interacting factor homolog (yeast)0.012
lhx1bLIM homeobox 1b0.012
suv39h1asuppressor of variegation 3-9 homolog 1a0.012
suv39h1bsuppressor of variegation 3-9 homolog 1b0.012
bonbonnie and clyde0.012
ilf3ainterleukin enhancer binding factor 3a0.012
vangl2vang-like 2 (van gogh, Drosophila)0.012
krt18keratin 180.011
gro2groucho 20.011
mcm4MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)0.011
cebp1CCAAT/enhancer binding protein (C/EBP) 10.011
ehmt2euchromatic histone-lysine N-methyltransferase 20.011
prdm9PR domain containing 90.011
ripk2receptor-interacting serine-threonine kinase 20.011
dharmadharma0.010
hbbe1.1hemoglobin beta embryonic-1.10.010
rhogbras homolog gene family, member Gb0.010
ctnnd2bcatenin (cadherin-associated protein), delta 2b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Su(var)205Suppressor of variegation 2050.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CBX5chromobox homolog 50.970
UHRF1ubiquitin-like with PHD and ring finger domains 10.566
PCNAproliferating cell nuclear antigen0.351
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.318
CBX3chromobox homolog 30.286
PARP1poly (ADP-ribose) polymerase 10.212
HIST1H3Bhistone cluster 1, H3b0.168
RPA2replication protein A2, 32kDa0.136
CBX1chromobox homolog 10.129
RPA1replication protein A1, 70kDa0.107
LBRlamin B receptor0.106
REREarginine-glutamic acid dipeptide (RE) repeats0.086
RBBP7retinoblastoma binding protein 70.064
EHMT1euchromatic histone-lysine N-methyltransferase 10.060
MBD1methyl-CpG binding domain protein 10.057
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.044
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.042
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.037
EEDembryonic ectoderm development0.036
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.035
CHAF1Achromatin assembly factor 1, subunit A (p150)0.033
SUZ12suppressor of zeste 12 homolog (Drosophila)0.030
RBBP4retinoblastoma binding protein 40.028
MSH6mutS homolog 6 (E. coli)0.027
LRIF1ligand dependent nuclear receptor interacting factor 10.026
SETDB1SET domain, bifurcated 10.026
IRS1insulin receptor substrate 10.025
PRRC2Bproline-rich coiled-coil 2B0.023
AXIN1axin 10.022
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.021
H2AFVH2A histone family, member V0.021
POLD3polymerase (DNA-directed), delta 3, accessory subunit0.019
EZH2enhancer of zeste homolog 2 (Drosophila)0.018
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.017
DDIT3DNA-damage-inducible transcript 30.016
HDAC1histone deacetylase 10.016
NRIP1nuclear receptor interacting protein 10.016
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.015
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.015
POGZpogo transposable element with ZNF domain0.015
TRIB1tribbles homolog 1 (Drosophila)0.014
ADNPactivity-dependent neuroprotector homeobox0.014
PLOD3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.014
TTI1Tel2 interacting protein 1 homolog (S. pombe)0.013
HMGA1high mobility group AT-hook 10.012
DNMT1DNA (cytosine-5-)-methyltransferase 10.012
ANP32Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.012
RARAretinoic acid receptor, alpha0.011
DUTdeoxyuridine triphosphatase0.011
CARM1coactivator-associated arginine methyltransferase 10.011
EGR1early growth response 10.011
DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 90.010
HMGN1high mobility group nucleosome binding domain 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anapc5anaphase-promoting complex subunit 50.100
Junbjun B proto-oncogene0.053
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.045
Adprhl2ADP-ribosylhydrolase like 20.042
Cobra1cofactor of BRCA10.033
Trim28tripartite motif-containing 280.029
Sec24bSEC24 family, member B (S. cerevisiae)0.021
Sart3squamous cell carcinoma antigen recognized by T-cells 30.020
Sympksymplekin0.020
Eif3beukaryotic translation initiation factor 3, subunit B0.020
Lsm14aLSM14A, SCD6 homolog A (S. cerevisiae)0.018
Rbm42RNA binding motif protein 420.018
Hcfc1host cell factor C10.017
Errfi1ERBB receptor feedback inhibitor 10.017
Phf12PHD finger protein 120.016
Scribscribbled homolog (Drosophila)0.015
Wizwidely-interspaced zinc finger motifs0.014
Tgs1trimethylguanosine synthase homolog (S. cerevisiae)0.013
Ralav-ral simian leukemia viral oncogene homolog A (ras related)0.013
Bat1HLA-B associated transcript 10.012
Lrrc47leucine rich repeat containing 470.011
CebpdCCAAT/enhancer binding protein (C/EBP), delta0.011
Eif2c2eukaryotic translation initiation factor 2C, 20.011
Guk1guanylate kinase 10.010
Aarsd1alanyl-tRNA synthetase domain containing 10.010
Ctbp1C-terminal binding protein 10.010
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism