The network for 'retinoid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retinoid metabolic process

The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.

NameDescriptionProbabilityFunc Analog Organism
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.987
Lratlecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)0.944
Stra6stimulated by retinoic acid gene 60.935
Rhorhodopsin0.629
Apohapolipoprotein H0.584
Aadacarylacetamide deacetylase (esterase)0.519
Abca4ATP-binding cassette, sub-family A (ABC1), member 40.394
Tcf7transcription factor 7, T-cell specific0.354
Nr1i2nuclear receptor subfamily 1, group I, member 20.350
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.346
Prph2peripherin 20.342
Edn2endothelin 20.339
Ahsgalpha-2-HS-glycoprotein0.337
Gsta3glutathione S-transferase, alpha 30.336
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.325
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.323
Apobapolipoprotein B0.290
Rdh16retinol dehydrogenase 160.290
Adh4alcohol dehydrogenase 4 (class II), pi polypeptide0.290
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.271
Ttrtransthyretin0.269
Slc22a1solute carrier family 22 (organic cation transporter), member 10.252
Crabp2cellular retinoic acid binding protein II0.249
Pparaperoxisome proliferator activated receptor alpha0.242
Cdhr5cadherin-related family member 50.238
Iydiodotyrosine deiodinase0.232
Slc17a1solute carrier family 17 (sodium phosphate), member 10.222
Ces2ecarboxylesterase 2E0.216
Mbl2mannose-binding lectin (protein C) 20.214
Cyp26c1cytochrome P450, family 26, subfamily c, polypeptide 10.213
Asgr2asialoglycoprotein receptor 20.201
Wnt5awingless-related MMTV integration site 5A0.201
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.199
Acaa2acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)0.197
Mdkmidkine0.197
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.196
Rbp1retinol binding protein 1, cellular0.195
Clcnkachloride channel Ka0.188
Ces1ccarboxylesterase 1C0.185
Apoa1apolipoprotein A-I0.177
H1fooH1 histone family, member O, oocyte-specific0.175
Agxtalanine-glyoxylate aminotransferase0.174
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.172
Nr1i3nuclear receptor subfamily 1, group I, member 30.170
Klkb1kallikrein B, plasma 10.165
Rdh7retinol dehydrogenase 70.162
Paplnpapilin, proteoglycan-like sulfated glycoprotein0.160
Cyp2c70cytochrome P450, family 2, subfamily c, polypeptide 700.157
Hgdhomogentisate 1, 2-dioxygenase0.154
Elovl3elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 30.152
Lama1laminin, alpha 10.151
Cdx2caudal type homeobox 20.150
F12coagulation factor XII (Hageman factor)0.146
Crabp1cellular retinoic acid binding protein I0.146
Sult1b1sulfotransferase family 1B, member 10.145
Ces2acarboxylesterase 2A0.143
Procprotein C0.137
Pitx2paired-like homeodomain transcription factor 20.135
Aadataminoadipate aminotransferase0.133
Inmtindolethylamine N-methyltransferase0.129
Ces1dcarboxylesterase 1D0.128
Apoc4apolipoprotein C-IV0.126
Trehtrehalase (brush-border membrane glycoprotein)0.126
Hrghistidine-rich glycoprotein0.123
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.121
D930020E02RikRIKEN cDNA D930020E02 gene0.121
Fmo1flavin containing monooxygenase 10.120
Ephx2epoxide hydrolase 2, cytoplasmic0.118
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.118
Pla2g12bphospholipase A2, group XIIB0.117
Dmgdhdimethylglycine dehydrogenase precursor0.114
Pon1paraoxonase 10.109
BC089597cDNA sequence BC0895970.108
Gcgrglucagon receptor0.108
Mettl7bmethyltransferase like 7B0.107
Rarres2retinoic acid receptor responder (tazarotene induced) 20.107
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.106
Cps1carbamoyl-phosphate synthetase 10.105
Apoa4apolipoprotein A-IV0.102
Fgf8fibroblast growth factor 80.102
Nrp1neuropilin 10.102
Fabp1fatty acid binding protein 1, liver0.100
G6pcglucose-6-phosphatase, catalytic0.099
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.099
Cidebcell death-inducing DNA fragmentation factor, alpha subunit-like effector B0.097
Nr0b2nuclear receptor subfamily 0, group B, member 20.097
Aqp8aquaporin 80.096
Hpgdhydroxyprostaglandin dehydrogenase 15 (NAD)0.094
Ces1gcarboxylesterase 1G0.093
Mep1bmeprin 1 beta0.091
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.091
Prr15proline rich 150.088
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.088
Krt5keratin 50.085
Sctsecretin0.083
Cmblcarboxymethylenebutenolidase-like (Pseudomonas)0.081
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.081
F13bcoagulation factor XIII, beta subunit0.080
Serpinc1serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 10.080
Nlrp6NLR family, pyrin domain containing 60.080
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
b2mbeta-2-microglobulin0.113
si:ch211-93f2.1si:ch211-93f2.10.083
fabp1b.1fatty acid binding protein 1b, tandem duplicate 10.081
tbpTATA box binding protein0.072
dhrs9dehydrogenase/reductase (SDR family) member 90.067
aldh2aaldehyde dehydrogenase 2 family (mitochondrial)a0.061
hprt1hypoxanthine phosphoribosyltransferase 10.060
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.059
wnt3awingless-type MMTV integration site family, member 3A0.059
rdh12retinol dehydrogenase 12 (all-trans and 9-cis)0.057
nr5a5nuclear receptor subfamily 5, group A, member 50.055
spry2sprouty homolog 20.055
srd5a2asteroid-5-alpha-reductase, alpha polypeptide 2a0.051
axin1axin 10.048
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.038
zgc:92406zgc:924060.037
fabp6fatty acid binding protein 6, ileal (gastrotropin)0.037
cyp4v2cytochrome P450, family 4, subfamily V, polypeptide 20.037
rdh1retinol dehydrogenase 10.036
ncoa2nuclear receptor coactivator 20.036
aldobaldolase b, fructose-bisphosphate0.036
cpa4carboxypeptidase A40.035
m17IL-6 subfamily cytokine M170.035
slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.034
hmx2H6 family homeobox 20.034
npy8brneuropeptide Y receptor Y8b0.033
zgc:172136zgc:1721360.032
sox9bSRY-box containing gene 9b0.031
bdh23-hydroxybutyrate dehydrogenase, type 20.031
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.031
aldh9a1aaldehyde dehydrogenase 9 family, member A1a0.030
gscgoosecoid0.030
fmo5flavin containing monooxygenase 50.030
foxl1forkhead box L10.029
aldh1a2aldehyde dehydrogenase 1 family, member A20.029
adh8aalcohol dehydrogenase 8a0.029
rgrbretinal G protein coupled receptor b0.028
opn4lopsin 4, like0.028
rorbRAR-related orphan receptor B0.027
wlswntless homolog (Drosophila)0.026
trytrypsin0.026
dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.026
bcdo2lbeta-carotene 15, 15-dioxygenase 2, like0.026
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.026
nme4non-metastatic cells 4, protein expressed in0.026
chia.2chitinase, acidic.20.026
gnrhr3gonadotropin releasing hormone receptor 30.025
sult1st3sulfotransferase family 1, cytosolic sulfotransferase 30.025
amy2aamylase, alpha 2A; pancreatic0.025
ela2lelastase 2 like0.024
rbp2aretinol binding protein 2a, cellular0.024
fabp2fatty acid binding protein 2, intestinal0.024
spry1sprouty homolog 1 (Drosophila)0.023
tm4sf4transmembrane 4 L six family member 40.023
cyp3a65cytochrome P450, family 3, subfamily A, polypeptide 650.023
gnrhr4gonadotropin releasing hormone receptor 40.022
mogat2monoacylglycerol O-acyltransferase 20.022
ddtD-dopachrome tautomerase0.022
epha7eph receptor A70.022
hbl3hexose-binding lectin 30.021
myh11amyosin, heavy polypeptide 11, smooth muscle a0.021
inhbbinhibin, beta B0.021
rgs4regulator of G-protein signalling 40.021
pcdh18bprotocadherin 18b0.020
tyrp1btyrosinase-related protein 1b0.020
lamb2laminin, beta 2 (laminin S)0.020
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.020
tfatransferrin-a0.020
acad11acyl-Coenzyme A dehydrogenase family, member 110.020
ccnhcyclin H0.020
restRE1-silencing transcription factor0.020
cyb5acytochrome b5 type A (microsomal)0.019
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.019
ihhaIndian hedgehog homolog a0.019
mtpmicrosomal triglyceride transfer protein0.019
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.018
acox1acyl-Coenzyme A oxidase 1, palmitoyl0.018
ext2exostoses (multiple) 20.018
aldh8a1aldehyde dehydrogenase 8 family, member A10.018
zgc:110418zgc:1104180.018
ef1aelongation factor 1-alpha0.017
ahctf1AT hook containing transcription factor 10.017
LOC100535672trypsin-1-like0.017
fgf20afibroblast growth factor 20a0.017
cry5cryptochrome 50.017
zgc:56622zgc:566220.017
pgm1phosphoglucomutase 10.017
slc26a1solute carrier family 26 (sulfate transporter), member 10.017
ctrb1chymotrypsinogen B10.017
ela3lelastase 3 like0.017
tskutsukushi small leucine rich proteoglycan homolog (Xenopus laevis)0.016
sfrp1asecreted frizzled-related protein 1a0.016
zgc:136461zgc:1364610.016
fzd5frizzled homolog 50.016
abp1amiloride binding protein 1 (amine oxidase (copper-containing))0.016
dctdopachrome tautomerase0.016
cap2CAP, adenylate cyclase-associated protein, 2 (yeast)0.016
foxp1bforkhead box P1b0.016
lmo4bLIM domain only 4b0.016
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG11570CG11570 gene product from transcript CG11570-RA0.015
retinophilinCG10233 gene product from transcript CG10233-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)1.000
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)1.000
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.999
BLOC1S2biogenesis of lysosomal organelles complex-1, subunit 20.548
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.412
TTRtransthyretin0.357
PEX14peroxisomal biogenesis factor 140.317
PRMT2protein arginine methyltransferase 20.107
ZHX1zinc fingers and homeoboxes 10.098
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.039
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.036
FBLN1fibulin 10.031
PEX5peroxisomal biogenesis factor 50.028
NUPR1nuclear protein, transcriptional regulator, 10.026
ECI2enoyl-CoA delta isomerase 20.023
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)0.022
AADACarylacetamide deacetylase (esterase)0.021
RNASE4ribonuclease, RNase A family, 40.020
SERPINA3serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 30.020
PEX19peroxisomal biogenesis factor 190.020
AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)0.020
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.020
CA12carbonic anhydrase XII0.019
NQO1NAD(P)H dehydrogenase, quinone 10.019
C2orf18chromosome 2 open reading frame 180.018
OTCornithine carbamoyltransferase0.018
GADD45Ggrowth arrest and DNA-damage-inducible, gamma0.017
C8Acomplement component 8, alpha polypeptide0.017
HABP2hyaluronan binding protein 20.017
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.017
C6complement component 60.016
CRYZcrystallin, zeta (quinone reductase)0.016
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.015
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.015
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.015
NDRG1N-myc downstream regulated 10.014
ECM2extracellular matrix protein 2, female organ and adipocyte specific0.014
RARRES2retinoic acid receptor responder (tazarotene induced) 20.013
GPX3glutathione peroxidase 3 (plasma)0.013
CATcatalase0.013
ADH1Aalcohol dehydrogenase 1A (class I), alpha polypeptide0.012
CES1carboxylesterase 10.012
ALDOBaldolase B, fructose-bisphosphate0.012
PLGplasminogen0.012
C1Rcomplement component 1, r subcomponent0.012
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.012
ALDH3A2aldehyde dehydrogenase 3 family, member A20.011
AOC3amine oxidase, copper containing 3 (vascular adhesion protein 1)0.011
NR1I2nuclear receptor subfamily 1, group I, member 20.011
GSTA3glutathione S-transferase alpha 30.011
HEXBhexosaminidase B (beta polypeptide)0.011
NR1H4nuclear receptor subfamily 1, group H, member 40.011
ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 110.011
KNG1kininogen 10.011
UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A10.010
LIPClipase, hepatic0.010
CD302CD302 molecule0.010
CCNG1cyclin G10.010
C10orf116chromosome 10 open reading frame 1160.010
AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.010
ADH6alcohol dehydrogenase 6 (class V)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.361
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.144
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.088
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.066
LOC293989cytochrome P450-like0.062
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.059
Ces1ecarboxylesterase 1E0.053
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.048
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.046
Fabp1fatty acid binding protein 1, liver0.042
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.041
Otcornithine carbamoyltransferase0.039
Akr1c18aldo-keto reductase family 1, member C180.039
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.038
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.036
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.035
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.032
Mettl7bmethyltransferase like 7B0.032
Ces1ccarboxylesterase 1C0.031
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.029
Fbp1fructose-1,6-bisphosphatase 10.026
Apoa2apolipoprotein A-II0.026
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.025
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.024
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.023
Gsta5glutathione S-transferase Yc2 subunit0.023
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.023
Mbl2mannose-binding lectin (protein C) 20.023
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.022
Ang1angiogenin, ribonuclease A family, member 10.021
Crybb1crystallin, beta B10.021
Gsta2glutathione S-transferase A20.019
LOC494499LOC494499 protein0.019
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.019
Hsd17b6hydroxysteroid (17-beta) dehydrogenase 60.018
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.018
Fabp12fatty acid binding protein 120.018
Aqp7aquaporin 70.018
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.018
Slc22a1solute carrier family 22 (organic cation transporter), member 10.018
A1i3alpha-1-inhibitor III0.018
Tdo2tryptophan 2,3-dioxygenase0.018
Ces1fcarboxylesterase 1F0.017
Xpnpep2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound0.017
Akr1c12aldo-keto reductase family 1, member C120.017
Aqp9aquaporin 90.016
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.016
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.016
Asgr2asialoglycoprotein receptor 20.016
Mosc1MOCO sulphurase C-terminal domain containing 10.015
Dpyddihydropyrimidine dehydrogenase0.015
Cyp2j4cytochrome P450, family 2, subfamily j, polypeptide 40.015
Mosc2MOCO sulphurase C-terminal domain containing 20.015
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.014
Dhfrdihydrofolate reductase0.014
Nr0b2nuclear receptor subfamily 0, group B, member 20.014
Ppargperoxisome proliferator-activated receptor gamma0.014
Muc13mucin 13, cell surface associated0.014
Acox2acyl-Coenzyme A oxidase 2, branched chain0.013
Inmtindolethylamine N-methyltransferase0.013
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.013
Pfkfb16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.013
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.013
Crygfcrystallin, gamma F0.013
Dpysdihydropyrimidinase0.013
Klkb1kallikrein B, plasma 10.013
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.013
Ces1dcarboxylesterase 1D0.013
Agxtalanine-glyoxylate aminotransferase0.012
Asgr1asialoglycoprotein receptor 10.012
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.012
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.012
Il1rl2interleukin 1 receptor-like 20.012
Chrm5cholinergic receptor, muscarinic 50.012
Ptgr1prostaglandin reductase 10.012
Ltb4rleukotriene B4 receptor0.012
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.012
Aadacarylacetamide deacetylase (esterase)0.012
Apobapolipoprotein B0.012
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.012
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.012
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.011
Mocosmolybdenum cofactor sulfurase0.011
Adh1alcohol dehydrogenase 1 (class I)0.011
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.011
Cyp27a1cytochrome P450, family 27, subfamily a, polypeptide 10.011
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.011
Mef2dmyocyte enhancer factor 2D0.011
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.011
Nat8N-acetyltransferase 80.011
LOC680367similar to Urinary protein 3 precursor (RUP-3)0.011
Hpd4-hydroxyphenylpyruvate dioxygenase0.011
Gys2glycogen synthase 20.011
Akr1c14aldo-keto reductase family 1, member C140.011
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.011
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.011
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.010
Mgst2microsomal glutathione S-transferase 20.010
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.010
Muc2mucin 2, oligomeric mucus/gel-forming0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism