The network for 'interleukin 1 alpha secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interleukin 1 alpha secretion

The regulated release of interleukin-1 alpha from a cell.

NameDescriptionProbabilityFunc Analog Organism
Casp4caspase 4, apoptosis-related cysteine peptidase0.971
Casp1caspase 10.951
Gbp5guanylate binding protein 50.814
Tlr4toll-like receptor 40.636
Il18interleukin 180.583
Aim2absent in melanoma 20.547
PycardPYD and CARD domain containing0.491
Il1binterleukin 1 beta0.171
Ripk3receptor-interacting serine-threonine kinase 30.121
FaddFas (TNFRSF6)-associated via death domain0.093
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.079
Hif1ahypoxia inducible factor 1, alpha subunit0.072
Anxa4annexin A40.066
Nlrp3NLR family, pyrin domain containing 30.055
Pax1paired box gene 10.055
Tnfsf10tumor necrosis factor (ligand) superfamily, member 100.053
Vamp8vesicle-associated membrane protein 80.039
Ly96lymphocyte antigen 960.038
S100a1S100 calcium binding protein A10.034
Elf4E74-like factor 4 (ets domain transcription factor)0.033
Gata1GATA binding protein 10.032
Aplnapelin0.030
Asah1N-acylsphingosine amidohydrolase 10.030
Rb1retinoblastoma 10.030
Nat2N-acetyltransferase 2 (arylamine N-acetyltransferase)0.028
Siaesialic acid acetylesterase0.027
Casp3caspase 30.027
Apaf1apoptotic peptidase activating factor 10.027
Hgfhepatocyte growth factor0.025
Gcet2germinal center expressed transcript 20.024
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.024
Armc10armadillo repeat containing 100.023
Ikzf2IKAROS family zinc finger 20.023
Lumlumican0.021
Birc3baculoviral IAP repeat-containing 30.021
Ptgirprostaglandin I receptor (IP)0.021
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.020
0610031J06RikRIKEN cDNA 0610031J06 gene0.020
Ccr1chemokine (C-C motif) receptor 10.020
Pqlc3PQ loop repeat containing0.019
Casp12caspase 120.019
Rnf38ring finger protein 380.019
NmiN-myc (and STAT) interactor0.019
Nfyanuclear transcription factor-Y alpha0.019
Sntb1syntrophin, basic 10.019
Wlswntless homolog (Drosophila)0.018
5033414D02RikRIKEN cDNA 5033414D02 gene0.018
Tff1trefoil factor 10.018
Ccr3chemokine (C-C motif) receptor 30.017
Sctsecretin0.017
Cd80CD80 antigen0.017
Cyp4v3cytochrome P450, family 4, subfamily v, polypeptide 30.016
Ctszcathepsin Z0.016
Emp3epithelial membrane protein 30.016
S1pr2sphingosine-1-phosphate receptor 20.016
Tlr7toll-like receptor 70.016
BC017643cDNA sequence BC0176430.016
Smad5MAD homolog 5 (Drosophila)0.016
Rab7l1RAB7, member RAS oncogene family-like 10.015
Pola1polymerase (DNA directed), alpha 10.015
Mc5rmelanocortin 5 receptor0.015
Tspan32tetraspanin 320.015
Galk2galactokinase 20.015
Leprotleptin receptor overlapping transcript0.015
Cd38CD38 antigen0.015
Dnase1l1deoxyribonuclease 1-like 10.015
Pgm1phosphoglucomutase 10.015
FasFas (TNF receptor superfamily member 6)0.015
C3ar1complement component 3a receptor 10.015
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.014
Il10rbinterleukin 10 receptor, beta0.014
Spg21spastic paraplegia 21 homolog (human)0.014
Sat1spermidine/spermine N1-acetyl transferase 10.014
WrnWerner syndrome homolog (human)0.014
F2rl2coagulation factor II (thrombin) receptor-like 20.014
Plscr1phospholipid scramblase 10.014
Brd8bromodomain containing 80.014
Casp8caspase 80.014
Cbfbcore binding factor beta0.014
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.014
Gusbglucuronidase, beta0.014
Ctsccathepsin C0.014
Il1r1interleukin 1 receptor, type I0.014
Clic1chloride intracellular channel 10.014
Mr1major histocompatibility complex, class I-related0.013
Rab3il1RAB3A interacting protein (rabin3)-like 10.013
Ptafrplatelet-activating factor receptor0.013
Scpep1serine carboxypeptidase 10.013
Serpinb1aserine (or cysteine) peptidase inhibitor, clade B, member 1a0.013
St3gal4ST3 beta-galactoside alpha-2,3-sialyltransferase 40.013
Tmpothymopoietin0.013
2210415F13RikRIKEN cDNA 2210415F13 gene0.013
Klf1Kruppel-like factor 1 (erythroid)0.013
Galnt4UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 40.013
Cpa3carboxypeptidase A3, mast cell0.013
Ptger1prostaglandin E receptor 1 (subtype EP1)0.013
BidBH3 interacting domain death agonist0.013
Tktl1transketolase-like 10.013
Med23mediator complex subunit 230.013
Serpinb9serine (or cysteine) peptidase inhibitor, clade B, member 90.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
S100A6S100 calcium binding protein A60.996
ANXA2annexin A20.927
MDM2Mdm2 p53 binding protein homolog (mouse)0.845
S100A11S100 calcium binding protein A110.714
S100A4S100 calcium binding protein A40.695
S100A10S100 calcium binding protein A100.608
S100BS100 calcium binding protein B0.595
FKBP4FK506 binding protein 4, 59kDa0.394
S100A16S100 calcium binding protein A160.359
AREGamphiregulin0.251
TMSB10thymosin beta 100.221
LGALS1lectin, galactoside-binding, soluble, 10.206
NLRC4NLR family, CARD domain containing 40.183
PLP2proteolipid protein 2 (colonic epithelium-enriched)0.126
CAPGcapping protein (actin filament), gelsolin-like0.054
LGALS3lectin, galactoside-binding, soluble, 30.044
S100A1S100 calcium binding protein A10.031
HIPK2homeodomain interacting protein kinase 20.031
ANXA1annexin A10.030
CASP4caspase 4, apoptosis-related cysteine peptidase0.030
S100A2S100 calcium binding protein A20.024
MDM4Mdm4 p53 binding protein homolog (mouse)0.024
EMP3epithelial membrane protein 30.022
CHEK2CHK2 checkpoint homolog (S. pombe)0.021
SFNstratifin0.020
RIPK2receptor-interacting serine-threonine kinase 20.020
GNL3Lguanine nucleotide binding protein-like 3 (nucleolar)-like0.017
PYCARDPYD and CARD domain containing0.017
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.015
AHNAKAHNAK nucleoprotein0.015
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.015
TSPOtranslocator protein (18kDa)0.014
CSTBcystatin B (stefin B)0.012
ANXA5annexin A50.012
GORABgolgin, RAB6-interacting0.011
CD63CD63 molecule0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism