The network for 'regulation of t cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of t cell proliferation

Any process that modulates the frequency, rate or extent of T cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
Cd40CD40 antigen0.998
Itgb1integrin beta 1 (fibronectin receptor beta)0.992
Efnb2ephrin B20.983
Lyz2lysozyme 20.974
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.953
Fgfr2fibroblast growth factor receptor 20.953
Tnfaip3tumor necrosis factor, alpha-induced protein 30.938
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.932
Batfbasic leucine zipper transcription factor, ATF-like0.924
Rnf2ring finger protein 20.896
Casp4caspase 4, apoptosis-related cysteine peptidase0.896
Ccr1chemokine (C-C motif) receptor 10.892
Stat3signal transducer and activator of transcription 30.889
Tnftumor necrosis factor0.889
Ccr7chemokine (C-C motif) receptor 70.865
Tgfb2transforming growth factor, beta 20.864
Cd28CD28 antigen0.859
BtkBruton agammaglobulinemia tyrosine kinase0.842
FasFas (TNF receptor superfamily member 6)0.840
Ptpn11protein tyrosine phosphatase, non-receptor type 110.820
Il1binterleukin 1 beta0.817
Ifnginterferon gamma0.811
Adam17a disintegrin and metallopeptidase domain 170.808
Foxp3forkhead box P30.795
Icosinducible T-cell co-stimulator0.794
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.790
Il4interleukin 40.782
RybpRING1 and YY1 binding protein0.782
Casp8caspase 80.780
Grb2growth factor receptor bound protein 20.770
Ltalymphotoxin A0.757
Ciitaclass II transactivator0.741
Zeb1zinc finger E-box binding homeobox 10.741
Ccl2chemokine (C-C motif) ligand 20.740
Stat5bsignal transducer and activator of transcription 5B0.734
Nlrp3NLR family, pyrin domain containing 30.717
Egfrepidermal growth factor receptor0.716
Cd3eCD3 antigen, epsilon polypeptide0.701
Itgalintegrin alpha L0.688
Traf6TNF receptor-associated factor 60.686
Gli2GLI-Kruppel family member GLI20.666
Stat5asignal transducer and activator of transcription 5A0.646
Pdcd1programmed cell death 10.645
Ubdubiquitin D0.645
H2-Eb1histocompatibility 2, class II antigen E beta0.644
Stat1signal transducer and activator of transcription 10.635
Clec4dC-type lectin domain family 4, member d0.633
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.626
Il12binterleukin 12b0.615
Stat2signal transducer and activator of transcription 20.588
Rb1retinoblastoma 10.585
Ctnnb1catenin (cadherin associated protein), beta 10.584
Ighimmunoglobulin heavy chain complex0.581
Foxc1forkhead box C10.577
Ccr5chemokine (C-C motif) receptor 50.577
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.567
Ccr2chemokine (C-C motif) receptor 20.562
Xcl1chemokine (C motif) ligand 10.547
Socs1suppressor of cytokine signaling 10.539
Cd19CD19 antigen0.538
Sh2d2aSH2 domain protein 2A0.531
Ntf3neurotrophin 30.530
Trp53transformation related protein 530.526
Cd7CD7 antigen0.514
Clec4nC-type lectin domain family 4, member n0.512
Smad6MAD homolog 6 (Drosophila)0.510
Smad4MAD homolog 4 (Drosophila)0.505
Gbp5guanylate binding protein 50.505
Traf2TNF receptor-associated factor 20.504
FaslFas ligand (TNF superfamily, member 6)0.496
Cyldcylindromatosis (turban tumor syndrome)0.493
Nf1neurofibromatosis 10.487
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.486
Il27rainterleukin 27 receptor, alpha0.477
Il1rninterleukin 1 receptor antagonist0.474
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.473
Cxcl9chemokine (C-X-C motif) ligand 90.472
Il2rginterleukin 2 receptor, gamma chain0.472
Birc3baculoviral IAP repeat-containing 30.467
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.451
Irf9interferon regulatory factor 90.451
FynFyn proto-oncogene0.444
Pthlhparathyroid hormone-like peptide0.442
Ccl3chemokine (C-C motif) ligand 30.435
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.430
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.428
Emx2empty spiracles homolog 2 (Drosophila)0.423
Cd86CD86 antigen0.423
Dok1docking protein 10.421
Jag1jagged 10.421
Mmp9matrix metallopeptidase 90.410
Ptgs2prostaglandin-endoperoxide synthase 20.409
Ccl8chemokine (C-C motif) ligand 80.409
Il6interleukin 60.406
Gli3GLI-Kruppel family member GLI30.406
Vegfavascular endothelial growth factor A0.402
Klrg1killer cell lectin-like receptor subfamily G, member 10.399
Il15rainterleukin 15 receptor, alpha chain0.397
Klrd1killer cell lectin-like receptor, subfamily D, member 10.396
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.393
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.987
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.982
CD80CD80 molecule0.982
BIRC3baculoviral IAP repeat containing 30.982
LATlinker for activation of T cells0.971
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.966
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.955
EGFRepidermal growth factor receptor0.934
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.932
GRB2growth factor receptor-bound protein 20.925
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.899
HLA-DMBmajor histocompatibility complex, class II, DM beta0.893
CD86CD86 molecule0.892
ICAM1intercellular adhesion molecule 10.871
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.856
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.853
SOCS3suppressor of cytokine signaling 30.837
HLA-Bmajor histocompatibility complex, class I, B0.826
CXCL9chemokine (C-X-C motif) ligand 90.825
HLA-Emajor histocompatibility complex, class I, E0.747
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.724
HLA-Gmajor histocompatibility complex, class I, G0.702
TRAF1TNF receptor-associated factor 10.673
BTN3A1butyrophilin, subfamily 3, member A10.651
CD247CD247 molecule0.651
CCR7chemokine (C-C motif) receptor 70.638
CCR5chemokine (C-C motif) receptor 50.585
BIRC2baculoviral IAP repeat containing 20.576
HLA-DRB5major histocompatibility complex, class II, DR beta 50.572
IL1R1interleukin 1 receptor, type I0.557
BTN3A3butyrophilin, subfamily 3, member A30.552
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.542
HLA-DPB1major histocompatibility complex, class II, DP beta 10.537
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.536
CTLA4cytotoxic T-lymphocyte-associated protein 40.521
IL2RGinterleukin 2 receptor, gamma0.519
CCL4chemokine (C-C motif) ligand 40.502
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.487
BCL10B-cell CLL/lymphoma 100.472
CD2CD2 molecule0.462
PTPRCprotein tyrosine phosphatase, receptor type, C0.455
CCL5chemokine (C-C motif) ligand 50.453
CASP9caspase 9, apoptosis-related cysteine peptidase0.446
SOS1son of sevenless homolog 1 (Drosophila)0.438
JAK2Janus kinase 20.428
CXCL10chemokine (C-X-C motif) ligand 100.421
HLA-Amajor histocompatibility complex, class I, A0.404
CCR1chemokine (C-C motif) receptor 10.389
CCL13chemokine (C-C motif) ligand 130.371
HLA-Fmajor histocompatibility complex, class I, F0.367
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.366
ABI1abl-interactor 10.365
CD163CD163 molecule0.364
BTN3A2butyrophilin, subfamily 3, member A20.359
IL2RBinterleukin 2 receptor, beta0.359
CCL2chemokine (C-C motif) ligand 20.345
HLA-DQB1major histocompatibility complex, class II, DQ beta 10.345
PLCG1phospholipase C, gamma 10.339
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.335
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.319
FCN1ficolin (collagen/fibrinogen domain containing) 10.304
LTAlymphotoxin alpha (TNF superfamily, member 1)0.299
BMPR1Abone morphogenetic protein receptor, type IA0.296
LCKlymphocyte-specific protein tyrosine kinase0.272
JAK1Janus kinase 10.259
CXCL2chemokine (C-X-C motif) ligand 20.245
TNFtumor necrosis factor0.238
CFLARCASP8 and FADD-like apoptosis regulator0.238
HK3hexokinase 3 (white cell)0.238
HLA-Cmajor histocompatibility complex, class I, C0.232
CD52CD52 molecule0.228
IL23Ainterleukin 23, alpha subunit p190.226
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.226
CCL22chemokine (C-C motif) ligand 220.225
CCL8chemokine (C-C motif) ligand 80.217
CCR2chemokine (C-C motif) receptor 20.214
HLA-DRB4major histocompatibility complex, class II, DR beta 40.212
IL1R2interleukin 1 receptor, type II0.211
FSTL1follistatin-like 10.203
CLEC10AC-type lectin domain family 10, member A0.195
AIF1allograft inflammatory factor 10.193
MS4A6Amembrane-spanning 4-domains, subfamily A, member 6A0.187
IL8interleukin 80.180
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.173
AOAHacyloxyacyl hydrolase (neutrophil)0.167
NLRP3NLR family, pyrin domain containing 30.167
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.166
CD28CD28 molecule0.162
IL10interleukin 100.161
SIGLEC7sialic acid binding Ig-like lectin 70.161
IL1Binterleukin 1, beta0.156
IL6interleukin 6 (interferon, beta 2)0.154
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.153
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.151
CD6CD6 molecule0.144
FPR3formyl peptide receptor 30.143
PTPN1protein tyrosine phosphatase, non-receptor type 10.143
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.140
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.138
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.955
RT1-DaRT1 class II, locus Da0.930
RT1-BbRT1 class II, locus Bb0.830
RT1-DMbRT1 class II, locus DMb0.616
Cd37CD37 molecule0.590
RT1-BaRT1 class II, locus Ba0.575
RT1-Db1RT1 class II, locus Db10.271
Cd53Cd53 molecule0.214
RT1-DMaRT1 class II, locus DMa0.109
Ptprcprotein tyrosine phosphatase, receptor type, C0.103
Hckhemopoietic cell kinase0.090
Cd44Cd44 molecule0.064
Laptm5lysosomal protein transmembrane 50.064
Cd247Cd247 molecule0.061
Il18interleukin 180.054
Lcp1lymphocyte cytosolic protein 10.046
Casp1caspase 10.035
Slfn2schlafen 20.033
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.029
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.027
Aif1allograft inflammatory factor 10.025
Ctsscathepsin S0.021
Vom2r27vomeronasal 2 receptor, 270.021
Il1binterleukin 1 beta0.021
Arpc1bactin related protein 2/3 complex, subunit 1B0.020
Icam1intercellular adhesion molecule 10.020
Dock8dedicator of cytokinesis 80.020
Prr13proline rich 130.019
Scp2sterol carrier protein 20.019
Lyz2lysozyme 20.018
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.018
Ciitaclass II, major histocompatibility complex, transactivator0.018
Cd2Cd2 molecule0.018
Capgcapping protein (actin filament), gelsolin-like0.017
Wipf1WAS/WASL interacting protein family, member 10.017
Il2rbinterleukin 2 receptor, beta0.017
Ptpn6protein tyrosine phosphatase, non-receptor type 60.017
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.017
Il7rinterleukin 7 receptor0.016
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.015
Bin2bridging integrator 20.015
Slasrc-like adaptor0.015
Rhogras homolog gene family, member G (rho G)0.015
Fgbfibrinogen beta chain0.015
Cxcl10chemokine (C-X-C motif) ligand 100.014
Arhgap4Rho GTPase activating protein 40.014
Iappislet amyloid polypeptide0.014
Itgb7integrin, beta 70.014
Fgafibrinogen alpha chain0.014
Inpp5dinositol polyphosphate-5-phosphatase D0.014
Sash3SAM and SH3 domain containing 30.013
Il6interleukin 60.013
Cfpcomplement factor properdin0.012
Igh-6immunoglobulin heavy chain 60.012
Neurl3neuralized homolog 3 (Drosophila)0.012
Batf3basic leucine zipper transcription factor, ATF-like 30.011
Taok1TAO kinase 10.011
Nfat5nuclear factor of activated T-cells 50.011
Sorbs1sorbin and SH3 domain containing 10.011
Aldh6a1aldehyde dehydrogenase 6 family, member A10.011
Jak2Janus kinase 20.011
Ehfets homologous factor0.010
Cd5Cd5 molecule0.010
Zbp1Z-DNA binding protein 10.010
Klf6Kruppel-like factor 60.010
Pdzk1ip1PDZK1 interacting protein 10.010
Ccl3chemokine (C-C motif) ligand 30.010
Sellselectin L0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism