The network for 'acetyl coa biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

acetyl coa biosynthetic process

The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.

NameDescriptionProbabilityFunc Analog Organism
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.986
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.220
Idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.212
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.161
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.125
Hibch3-hydroxyisobutyryl-Coenzyme A hydrolase0.116
Etfaelectron transferring flavoprotein, alpha polypeptide0.110
Gfm1G elongation factor, mitochondrial 10.107
AclyATP citrate lyase0.105
Uqcrc2ubiquinol cytochrome c reductase core protein 20.100
Pdha1pyruvate dehydrogenase E1 alpha 10.094
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.080
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.076
Vdac2voltage-dependent anion channel 20.072
Suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.064
Ndufaf1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 10.060
Fh1fumarate hydratase 10.049
Hibadh3-hydroxyisobutyrate dehydrogenase0.049
Etfdhelectron transferring flavoprotein, dehydrogenase0.047
Acad11acyl-Coenzyme A dehydrogenase family, member 110.046
Cyp51cytochrome P450, family 510.041
Tmem70transmembrane protein 700.040
Cscitrate synthase0.040
Cycscytochrome c, somatic0.037
Echdc1enoyl Coenzyme A hydratase domain containing 10.034
Iars2isoleucine-tRNA synthetase 2, mitochondrial0.033
Liaslipoic acid synthetase0.032
Lpin1lipin 10.032
Bnip3BCL2/adenovirus E1B interacting protein 30.032
Pex7peroxisomal biogenesis factor 70.031
Acat2acetyl-Coenzyme A acetyltransferase 20.030
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.029
Stard7START domain containing 70.027
Mrpl39mitochondrial ribosomal protein L390.026
Ndrg2N-myc downstream regulated gene 20.026
Macrod1MACRO domain containing 10.024
Entpd5ectonucleoside triphosphate diphosphohydrolase 50.024
Mmachcmethylmalonic aciduria cblC type, with homocystinuria0.023
Lactb2lactamase, beta 20.022
Adck3aarF domain containing kinase 30.022
Mtx2metaxin 20.021
Pmpcbpeptidase (mitochondrial processing) beta0.021
Sod2superoxide dismutase 2, mitochondrial0.020
Grsf1G-rich RNA sequence binding factor 10.020
Hspa9heat shock protein 90.020
Mutmethylmalonyl-Coenzyme A mutase0.019
Acsl1acyl-CoA synthetase long-chain family member 10.019
Hsdl2hydroxysteroid dehydrogenase like 20.018
Bckdhbbranched chain ketoacid dehydrogenase E1, beta polypeptide0.018
Afg3l2AFG3(ATPase family gene 3)-like 2 (yeast)0.018
Fasnfatty acid synthase0.017
Dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.017
Isca1iron-sulfur cluster assembly 1 homolog (S. cerevisiae)0.017
Coq3coenzyme Q3 homolog, methyltransferase (yeast)0.016
Uqcrbubiquinol-cytochrome c reductase binding protein0.015
Chac2ChaC, cation transport regulator homolog 2 (E. coli)0.015
Mtch2mitochondrial carrier homolog 2 (C. elegans)0.015
Lrpprcleucine-rich PPR-motif containing0.015
Sqlesqualene epoxidase0.015
Ghitmgrowth hormone inducible transmembrane protein0.014
Haghhydroxyacyl glutathione hydrolase0.014
Pdhxpyruvate dehydrogenase complex, component X0.014
Scd1stearoyl-Coenzyme A desaturase 10.013
Atl2atlastin GTPase 20.013
Pink1PTEN induced putative kinase 10.013
Mtif2mitochondrial translational initiation factor 20.013
Tmx2thioredoxin-related transmembrane protein 20.013
Lsslanosterol synthase0.013
Lace1lactation elevated 10.013
Chpt1choline phosphotransferase 10.012
Slc25a23solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 230.012
Immtinner membrane protein, mitochondrial0.012
Chchd3coiled-coil-helix-coiled-coil-helix domain containing 30.012
Dhcr77-dehydrocholesterol reductase0.011
Sucla2succinate-Coenzyme A ligase, ADP-forming, beta subunit0.011
Idi1isopentenyl-diphosphate delta isomerase0.011
Cd36CD36 antigen0.011
Mccc1methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)0.011
Ppa2pyrophosphatase (inorganic) 20.011
Ivdisovaleryl coenzyme A dehydrogenase0.011
Aldh4a1aldehyde dehydrogenase 4 family, member A10.011
Opa1optic atrophy 1 homolog (human)0.011
Mtfp1mitochondrial fission process 10.011
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.010
Ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 40.010
2310061I04RikRIKEN cDNA 2310061I04 gene0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hsf2heat shock factor 20.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDHXpyruvate dehydrogenase complex, component X0.916
DLATdihydrolipoamide S-acetyltransferase0.617
PDHBpyruvate dehydrogenase (lipoamide) beta0.335
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.170
DLDdihydrolipoamide dehydrogenase0.037
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.767
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.622
Uqcrc2ubiquinol cytochrome c reductase core protein 20.413
Dlddihydrolipoamide dehydrogenase0.342
Cycscytochrome c, somatic0.311
Me1malic enzyme 1, NADP(+)-dependent, cytosolic0.172
Pink1PTEN induced putative kinase 10.118
RGD1565095similar to hypothetical protein MGC521100.068
Ube2bubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)0.063
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.061
Tecrtrans-2,3-enoyl-CoA reductase0.050
Vdac1voltage-dependent anion channel 10.041
Pdha1pyruvate dehydrogenase (lipoamide) alpha 10.040
Pdhxpyruvate dehydrogenase complex, component X0.038
Bpnt13'(2'), 5'-bisphosphate nucleotidase 10.036
Trappc6btrafficking protein particle complex 6B0.036
Dlatdihydrolipoamide S-acetyltransferase0.032
Dynlt3dynein light chain Tctex-type 30.030
Ccng1cyclin G10.024
RGD1310686similar to chromosome 16 open reading frame 50.022
Tfrctransferrin receptor0.022
Tom1target of myb1 homolog (chicken)0.021
Gstm2glutathione S-transferase mu 20.016
Fxyd1FXYD domain-containing ion transport regulator 10.016
Fdft1farnesyl diphosphate farnesyl transferase 10.015
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.015
Senp2Sumo1/sentrin/SMT3 specific peptidase 20.014
Oxct13-oxoacid CoA transferase 10.014
Cdadc1cytidine and dCMP deaminase domain containing 10.014
Mtx2metaxin 20.013
Synj2bpsynaptojanin 2 binding protein0.012
Uba3ubiquitin-like modifier activating enzyme 30.011
Rab5aRAB5A, member RAS oncogene family0.011
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.011
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.010
Atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B10.010
Sucla2succinate-CoA ligase, ADP-forming, beta subunit0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PDB1Pdb1p0.038
LAT1Lat1p0.027
PDA1Pda1p0.021
LPD1Lpd1p0.016
CYM1Cym1p0.015