The network for 'cellular aldehyde metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular aldehyde metabolic process

The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.

NameDescriptionProbabilityFunc Analog Organism
Ldhalactate dehydrogenase A0.939
Aldoaaldolase A, fructose-bisphosphate0.606
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.501
Pgk1phosphoglycerate kinase 10.456
Gm5506predicted gene 55060.428
Taldo1transaldolase 10.419
Pkm2pyruvate kinase, muscle0.343
Kiss1KiSS-1 metastasis-suppressor0.331
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.330
Adh1alcohol dehydrogenase 1 (class I)0.316
Samm50sorting and assembly machinery component 50 homolog (S. cerevisiae)0.269
Ednraendothelin receptor type A0.238
Qdprquinoid dihydropteridine reductase0.217
Tpi1triosephosphate isomerase 10.199
Pgam1phosphoglycerate mutase 10.193
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.191
Sirt3sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)0.187
Tcfap2atranscription factor AP-2, alpha0.160
Rdh16retinol dehydrogenase 160.157
Gnrh1gonadotropin releasing hormone 10.144
Lratlecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)0.142
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.141
Gcshglycine cleavage system protein H (aminomethyl carrier)0.125
Idi1isopentenyl-diphosphate delta isomerase0.113
Foxc2forkhead box C20.111
Rarbretinoic acid receptor, beta0.106
Amhr2anti-Mullerian hormone type 2 receptor0.105
Prdx1peroxiredoxin 10.100
Gsta3glutathione S-transferase, alpha 30.100
Pdha2pyruvate dehydrogenase E1 alpha 20.097
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.088
Acsm1acyl-CoA synthetase medium-chain family member 10.087
Aldh1a7aldehyde dehydrogenase family 1, subfamily A70.086
Pgdphosphogluconate dehydrogenase0.085
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.085
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.084
Aadacarylacetamide deacetylase (esterase)0.079
Hgdhomogentisate 1, 2-dioxygenase0.078
F12coagulation factor XII (Hageman factor)0.078
Adh4alcohol dehydrogenase 4 (class II), pi polypeptide0.075
Rargretinoic acid receptor, gamma0.072
Aadataminoadipate aminotransferase0.071
Nrp1neuropilin 10.068
Lhcgrluteinizing hormone/choriogonadotropin receptor0.066
Mbl1mannose-binding lectin (protein A) 10.065
Hrghistidine-rich glycoprotein0.064
Kif27kinesin family member 270.063
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.061
Clk1CDC-like kinase 10.060
Pon1paraoxonase 10.059
Dbidiazepam binding inhibitor0.059
Ces1ccarboxylesterase 1C0.058
Aldh1a1aldehyde dehydrogenase family 1, subfamily A10.056
Car5acarbonic anhydrase 5a, mitochondrial0.054
Gpi1glucose phosphate isomerase 10.053
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.053
Rdh10retinol dehydrogenase 10 (all-trans)0.053
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.051
Nhlh2nescient helix loop helix 20.048
Bcap31B-cell receptor-associated protein 310.048
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.048
Cyp2d12cytochrome P450, family 2, subfamily d, polypeptide 120.047
Uoxurate oxidase0.047
Mesp1mesoderm posterior 10.046
Fbln1fibulin 10.045
Slc17a1solute carrier family 17 (sodium phosphate), member 10.045
Wnt5awingless-related MMTV integration site 5A0.045
Cyb5cytochrome b-50.044
Tgfbr2transforming growth factor, beta receptor II0.043
Gsta2glutathione S-transferase, alpha 2 (Yc2)0.042
Cpsf3cleavage and polyadenylation specificity factor 30.039
Apohapolipoprotein H0.039
Cyp26c1cytochrome P450, family 26, subfamily c, polypeptide 10.039
Inmtindolethylamine N-methyltransferase0.039
Pepdpeptidase D0.038
Pfklphosphofructokinase, liver, B-type0.038
Tattyrosine aminotransferase0.038
Ufc1ubiquitin-fold modifier conjugating enzyme 10.038
Pebp1phosphatidylethanolamine binding protein 10.037
Cndp2CNDP dipeptidase 2 (metallopeptidase M20 family)0.036
Fmn1formin 10.035
Fuca1fucosidase, alpha-L- 1, tissue0.034
Slco1a1solute carrier organic anion transporter family, member 1a10.034
Cdhr5cadherin-related family member 50.033
Xpnpep1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble0.033
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.033
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.032
Ak2adenylate kinase 20.032
C9complement component 90.032
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.031
AclyATP citrate lyase0.031
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.030
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.029
G6pcglucose-6-phosphatase, catalytic0.029
Ulk4unc-51-like kinase 4 (C. elegans)0.029
Nr0b2nuclear receptor subfamily 0, group B, member 20.027
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
aldh1a2aldehyde dehydrogenase 1 family, member A20.953
gnrhr3gonadotropin releasing hormone receptor 30.445
apoebapolipoprotein Eb0.263
ftr82finTRIM family, member 820.248
gja3gap junction protein, alpha 30.234
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.219
rdh12retinol dehydrogenase 12 (all-trans and 9-cis)0.205
rgrbretinal G protein coupled receptor b0.201
nr5a5nuclear receptor subfamily 5, group A, member 50.188
tbpTATA box binding protein0.178
stra6stimulated by retinoic acid gene 6 homolog (mouse)0.170
hsp90a.2heat shock protein 90-alpha 20.167
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.162
dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.158
restRE1-silencing transcription factor0.152
gnrhr4gonadotropin releasing hormone receptor 40.144
gata5GATA-binding protein 50.134
dhrs3adehydrogenase/reductase (SDR family) member 3a0.123
dpyddihydropyrimidine dehydrogenase0.121
pgm1phosphoglucomutase 10.119
scn4aasodium channel, voltage-gated, type IV, alpha, a0.112
slc3a2solute carrier family 3, member 20.101
mychmyelocytomatosis oncogene homolog0.100
gpiaglucose phosphate isomerase a0.093
tyrp1btyrosinase-related protein 1b0.089
rdh8retinol dehydrogenase 80.088
eno3enolase 3, (beta, muscle)0.087
scn4absodium channel, voltage-gated, type IV, alpha, b0.085
nme4non-metastatic cells 4, protein expressed in0.082
adh5alcohol dehydrogenase 50.080
vtg7vitellogenin 70.079
scp2sterol carrier protein 20.078
gnrh2gonadotropin-releasing hormone 20.076
pgk1phosphoglycerate kinase 10.075
prox2prospero homeobox 20.075
hprt1hypoxanthine phosphoribosyltransferase 10.075
fabp10afatty acid binding protein 10a, liver basic0.074
gapdhglyceraldehyde-3-phosphate dehydrogenase0.072
aldh9a1aaldehyde dehydrogenase 9 family, member A1a0.071
gapdhsglyceraldehyde-3-phosphate dehydrogenase, spermatogenic0.071
hspb1heat shock protein, alpha-crystallin-related, 10.068
cyp3c1cytochrome P450, family 3, subfamily c, polypeptide 10.064
aldh2aaldehyde dehydrogenase 2 family (mitochondrial)a0.061
itgb1b.1integrin, beta 1b.10.061
pepdpeptidase D0.059
rdh5retinol dehydrogenase 5 (11-cis/9-cis)0.058
srd5a2asteroid-5-alpha-reductase, alpha polypeptide 2a0.055
ocrloculocerebrorenal syndrome of Lowe0.054
tbx5aT-box 5a0.052
ppp1r3caprotein phosphatase 1, regulatory (inhibitor) subunit 3Ca0.049
hnf1baHNF1 homeobox Ba0.048
esdesterase D/formylglutathione hydrolase0.048
furinbfurin (paired basic amino acid cleaving enzyme) b0.048
rgs4regulator of G-protein signalling 40.047
cyb5acytochrome b5 type A (microsomal)0.045
cyp51cytochrome P450, family 510.044
bdh23-hydroxybutyrate dehydrogenase, type 20.044
nkx2.5NK2 transcription factor related 50.043
foxa3forkhead box A30.043
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.043
ctsccathepsin C0.042
obscnobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.042
flot1bflotillin 1b0.041
il17rdinterleukin 17 receptor D0.040
igfbp6ainsulin-like growth factor binding protein 6a0.040
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.040
aldh6a1aldehyde dehydrogenase 6 family, member A10.039
cyp4v2cytochrome P450, family 4, subfamily V, polypeptide 20.039
pdlim7PDZ and LIM domain 70.038
lpllipoprotein lipase0.038
aldh8a1aldehyde dehydrogenase 8 family, member A10.037
foxl1forkhead box L10.037
ak3adenylate kinase 30.036
faddFas (tnfrsf6)-associated via death domain0.036
igfbp6binsulin-like growth factor binding protein 6b0.036
dync1h1dynein, cytoplasmic 1, heavy chain 10.036
cygb1cytoglobin 10.035
ncf1neutrophil cytosolic factor 10.035
aldoaaaldolase a, fructose-bisphosphate, a0.035
agxt2l1alanine-glyoxylate aminotransferase 2-like 10.034
rbpms2RNA binding protein with multiple splicing 20.034
ccnhcyclin H0.034
insl5ainsulin-like 5a0.033
rbp7bretinol binding protein 7b, cellular0.033
fabp1b.1fatty acid binding protein 1b, tandem duplicate 10.033
wnt11wingless-type MMTV integration site family, member 110.033
agmoalkylglycerol monooxygenase0.033
tbx1T-box 10.031
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG7998CG7998 gene product from transcript CG7998-RA0.341
CG15754CG15754 gene product from transcript CG15754-RA0.233
AldhAldehyde dehydrogenase0.176
CG11151CG11151 gene product from transcript CG11151-RA0.173
GstE6Glutathione S transferase E60.170
aralar1CG2139 gene product from transcript CG2139-RC0.083
CG1314CG1314 gene product from transcript CG1314-RA0.072
PHGPxCG12013 gene product from transcript CG12013-RC0.067
Got2Glutamate oxaloacetate transaminase 20.067
CG10863CG10863 gene product from transcript CG10863-RA0.055
CG18522CG18522 gene product from transcript CG18522-RA0.051
pyd3CG3027 gene product from transcript CG3027-RA0.044
CG6776CG6776 gene product from transcript CG6776-RA0.042
ThiolaseCG4581 gene product from transcript CG4581-RA0.039
CG9510CG9510 gene product from transcript CG9510-RC0.038
CG6084CG6084 gene product from transcript CG6084-RB0.037
CG1319CG1319 gene product from transcript CG1319-RB0.035
InosCG11143 gene product from transcript CG11143-RA0.035
CG7970CG7970 gene product from transcript CG7970-RA0.034
CG6045CG6045 gene product from transcript CG6045-RA0.034
CG3902CG3902 gene product from transcript CG3902-RA0.033
CG18003CG18003 gene product from transcript CG18003-RA0.027
EfrER GDP-fucose transporter0.026
granny-smithgranny smith0.025
CG5167CG5167 gene product from transcript CG5167-RA0.025
CG8036CG8036 gene product from transcript CG8036-RB0.025
ND75NADH:ubiquinone reductase 75kD subunit precursor0.023
CG14290CG14290 gene product from transcript CG14290-RB0.022
CG3415CG3415 gene product from transcript CG3415-RA0.022
nAcRbeta-96Anicotinic Acetylcholine Receptor beta 96A0.020
CG12171CG12171 gene product from transcript CG12171-RA0.019
CG3609CG3609 gene product from transcript CG3609-RA0.019
CG3835CG3835 gene product from transcript CG3835-RB0.019
CG18547CG18547 gene product from transcript CG18547-RA0.018
retinophilinCG10233 gene product from transcript CG10233-RA0.018
yip2yippee interacting protein 20.016
CG31937CG31937 gene product from transcript CG31937-RA0.016
CG3603CG3603 gene product from transcript CG3603-RA0.016
CG17261CG17261 gene product from transcript CG17261-RA0.015
CG5987CG5987 gene product from transcript CG5987-RA0.015
CG30427CG30427 gene product from transcript CG30427-RC0.015
CG7077CG7077 gene product from transcript CG7077-RA0.015
ortora transientless0.014
CG6028CG6028 gene product from transcript CG6028-RA0.014
CG15784CG15784 gene product from transcript CG15784-RA0.013
TpiTriose phosphate isomerase0.013
CG5335CG5335 gene product from transcript CG5335-RA0.013
IdhIsocitrate dehydrogenase0.012
ninaAneither inactivation nor afterpotential A0.012
CG1827CG1827 gene product from transcript CG1827-RC0.012
CG5707CG5707 gene product from transcript CG5707-RA0.011
PyKPyruvate kinase0.011
RfabgRetinoid- and fatty acid-binding glycoprotein0.011
Cyp6g2CG8859 gene product from transcript CG8859-RA0.010
PgdPhosphogluconate dehydrogenase0.010
CG10301CG10301 gene product from transcript CG10301-RB0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.780
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.658
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.619
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.508
ALDH1A1aldehyde dehydrogenase 1 family, member A10.346
ENO1enolase 1, (alpha)0.296
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.287
TALDO1transaldolase 10.279
ALDOBaldolase B, fructose-bisphosphate0.243
ALDH2aldehyde dehydrogenase 2 family (mitochondrial)0.210
ARandrogen receptor0.138
BLOC1S2biogenesis of lysosomal organelles complex-1, subunit 20.090
PRDX1peroxiredoxin 10.077
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.076
RXRAretinoid X receptor, alpha0.057
PGAM1phosphoglycerate mutase 1 (brain)0.055
SOD1superoxide dismutase 1, soluble0.036
NCOA2nuclear receptor coactivator 20.026
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)0.026
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.025
PRMT2protein arginine methyltransferase 20.023
PRDX6peroxiredoxin 60.022
G6PDglucose-6-phosphate dehydrogenase0.021
FHL2four and a half LIM domains 20.019
MGEA5meningioma expressed antigen 5 (hyaluronidase)0.019
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.018
DAD1defender against cell death 10.018
CRYZcrystallin, zeta (quinone reductase)0.018
C2orf18chromosome 2 open reading frame 180.018
HADHhydroxyacyl-CoA dehydrogenase0.016
CA12carbonic anhydrase XII0.016
ATXN10ataxin 100.015
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.015
ALDOAaldolase A, fructose-bisphosphate0.015
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.015
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.014
RLFrearranged L-myc fusion0.014
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.014
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.014
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.013
METRNmeteorin, glial cell differentiation regulator0.013
PEBP1phosphatidylethanolamine binding protein 10.013
PGDphosphogluconate dehydrogenase0.012
ADH1Aalcohol dehydrogenase 1A (class I), alpha polypeptide0.012
ATG14ATG14 autophagy related 14 homolog (S. cerevisiae)0.012
HSD17B4hydroxysteroid (17-beta) dehydrogenase 40.012
EPHX1epoxide hydrolase 1, microsomal (xenobiotic)0.012
NUPR1nuclear protein, transcriptional regulator, 10.012
MXI1MAX interactor 10.012
CCNL1cyclin L10.011
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.011
ALDH3A2aldehyde dehydrogenase 3 family, member A20.011
RNASE4ribonuclease, RNase A family, 40.011
PRKCDprotein kinase C, delta0.011
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.010
ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide0.010
RUNX1runt-related transcription factor 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Aldoaaldolase A, fructose-bisphosphate0.202
Cyb5acytochrome b5 type A (microsomal)0.028
Triap1TP53 regulated inhibitor of apoptosis 10.021
Pkm2pyruvate kinase, muscle0.018
Mosc2MOCO sulphurase C-terminal domain containing 20.017
Oaz1ornithine decarboxylase antizyme 10.016
Mocs2molybdenum cofactor synthesis 20.015
Adh1alcohol dehydrogenase 1 (class I)0.014
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.011
Rplp2ribosomal protein, large P20.011
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.011
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.011
Park7Parkinson disease (autosomal recessive, early onset) 70.011
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.010
Ptgr1prostaglandin reductase 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism