The network for 'lateral line system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lateral line system development

The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.

NameDescriptionProbabilityFunc Analog Organism
Espnespin0.934
Msx1homeobox, msh-like 10.920
Hoxb1homeobox B10.869
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.764
Sox9SRY-box containing gene 90.705
Ush1gUsher syndrome 1G homolog (human)0.689
Shhsonic hedgehog0.687
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.687
Tbx1T-box 10.686
Isl1ISL1 transcription factor, LIM/homeodomain0.663
Ntf3neurotrophin 30.652
Sox10SRY-box containing gene 100.649
Dlx5distal-less homeobox 50.648
Retret proto-oncogene0.627
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.618
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.599
Neurod1neurogenic differentiation 10.597
Ptpn11protein tyrosine phosphatase, non-receptor type 110.575
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.567
Il6stinterleukin 6 signal transducer0.564
Hoxa1homeobox A10.556
Nrg1neuregulin 10.548
Mpdzmultiple PDZ domain protein0.540
Pax2paired box gene 20.509
Gsk3bglycogen synthase kinase 3 beta0.493
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.489
Ascl1achaete-scute complex homolog 1 (Drosophila)0.481
Phox2bpaired-like homeobox 2b0.473
Hmx3H6 homeobox 30.469
Gdnfglial cell line derived neurotrophic factor0.447
Neurod4neurogenic differentiation 40.421
Otx2orthodenticle homolog 2 (Drosophila)0.406
Arandrogen receptor0.401
Ebf3early B-cell factor 30.382
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.370
Gbx2gastrulation brain homeobox 20.369
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.364
Pax9paired box gene 90.354
Tectatectorin alpha0.352
Neurog1neurogenin 10.342
Leprleptin receptor0.337
Pbx1pre B-cell leukemia transcription factor 10.301
Ctnnb1catenin (cadherin associated protein), beta 10.291
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.286
Il6interleukin 60.285
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.285
Chrdchordin0.283
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.276
Eya1eyes absent 1 homolog (Drosophila)0.268
Ppargperoxisome proliferator activated receptor gamma0.268
Nr2f2nuclear receptor subfamily 2, group F, member 20.264
Srrm4serine/arginine repetitive matrix 40.257
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.254
Stat3signal transducer and activator of transcription 30.246
Ap2m1adaptor protein complex AP-2, mu10.244
Hoxa10homeobox A100.240
Egr1early growth response 10.240
Cdh23cadherin 23 (otocadherin)0.239
Lrp6low density lipoprotein receptor-related protein 60.238
Gli3GLI-Kruppel family member GLI30.236
Pax3paired box gene 30.235
Lepleptin0.232
Rac1RAS-related C3 botulinum substrate 10.230
Atp6v0bATPase, H+ transporting, lysosomal V0 subunit B0.223
Egr2early growth response 20.223
Runx2runt related transcription factor 20.220
Foxa2forkhead box A20.218
Ghrgrowth hormone receptor0.217
Cd44CD44 antigen0.207
Tmc1transmembrane channel-like gene family 10.194
Nab2Ngfi-A binding protein 20.193
Col22a1collagen, type XXII, alpha 10.191
Ush1cUsher syndrome 1C homolog (human)0.191
Neurog2neurogenin 20.187
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.185
Tcfap2ctranscription factor AP-2, gamma0.183
Wnt3awingless-related MMTV integration site 3A0.180
Hoxa4homeobox A40.180
Wnt1wingless-related MMTV integration site 10.168
Zic2zinc finger protein of the cerebellum 20.167
Nkx3-2NK3 homeobox 20.167
Hoxd3homeobox D30.165
JunbJun-B oncogene0.163
Gli2GLI-Kruppel family member GLI20.162
En1engrailed 10.159
Gas1growth arrest specific 10.158
Wnt5awingless-related MMTV integration site 5A0.156
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.154
Grip1glutamate receptor interacting protein 10.153
Ptk7PTK7 protein tyrosine kinase 70.146
Tcf7transcription factor 7, T-cell specific0.145
Cyr61cysteine rich protein 610.145
Shox2short stature homeobox 20.145
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.144
Gscgoosecoid homeobox0.144
Hmx1H6 homeobox 10.142
Gli1GLI-Kruppel family member GLI10.142
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.136
Rtn4rreticulon 4 receptor0.134
Insm1insulinoma-associated 10.132
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
eya1eyes absent homolog 10.999
lmx1b.1LIM homeobox transcription factor 1, beta 10.998
sox10SRY-box containing gene 100.983
hoxc8ahomeo box C8a0.979
lef1lymphocyte enhancer binding factor 10.965
hoxc4ahomeo box C4a0.949
cldnbclaudin b0.938
gria4aglutamate receptor, ionotropic, AMPA 4a0.930
hoxb8ahomeo box B8a0.927
cldnhclaudin h0.921
pcsk5aproprotein convertase subtilisin/kexin type 5a0.901
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.878
metmet proto-oncogene (hepatocyte growth factor receptor)0.870
hmx3homeo box (H6 family) 30.868
notch3notch homolog 30.853
cdh6cadherin 60.840
atoh1aatonal homolog 1a0.830
alcamaactivated leukocyte cell adhesion molecule a0.828
epcamepithelial cell adhesion molecule0.822
kal1aKallmann syndrome 1a sequence0.809
hoxb6ahomeo box B6a0.807
hoxb5bhomeo box B5b0.784
foxp1bforkhead box P1b0.748
hsd17b12ahydroxysteroid (17-beta) dehydrogenase 12a0.747
hoxa4ahomeo box A4a0.729
spry1sprouty homolog 1 (Drosophila)0.726
cxcr4bchemokine (C-X-C motif), receptor 4b0.712
neurog1neurogenin 10.710
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.693
myo7aamyosin VIIAa0.681
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.679
hoxd4ahomeo box D4a0.669
scn1bbsodium channel, voltage-gated, type I, beta b0.637
hoxb6bhomeo box B6b0.618
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.604
nrg1neuregulin 10.597
fgf3fibroblast growth factor 30.592
gbx2gastrulation brain homeo box 20.589
hnf1baHNF1 homeobox Ba0.575
gria4bglutamate receptor, ionotropic, AMPA 4b0.571
lmx1b.2LIM homeobox transcription factor 1, beta 20.557
fgf10afibroblast growth factor 10a0.532
hoxb4ahomeo box B4a0.530
dkk1bdickkopf 1b0.527
cldn7bclaudin 7b0.508
kdrlkinase insert domain receptor like0.499
rorbRAR-related orphan receptor B0.495
spint1aserine peptidase inhibitor, Kunitz type 1 a0.480
wnt4awingless-type MMTV integration site family, member 4a0.477
grhl2bgrainyhead-like 2b (Drosophila)0.476
gata3GATA-binding protein 30.471
si:dkeyp-7c9.1si:dkeyp-7c9.10.471
irx2airoquois homeobox protein 2, a0.454
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.443
hoxb5ahomeo box B5a0.433
sncbsynuclein, beta0.423
gpr126G protein-coupled receptor 1260.423
cntn2contactin 20.418
egr1early growth response 10.417
irx1biroquois homeobox protein 1, b0.415
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.402
pcsk9proprotein convertase subtilisin/kexin type 90.396
ndrg1N-myc downstream regulated gene 10.391
gria1aglutamate receptor, ionotropic, AMPA 1a0.389
atoh1batonal homolog 1b0.388
pcsk5bproprotein convertase subtilisin/kexin type 5b0.387
mbpmyelin basic protein0.386
prox1prospero-related homeobox gene 10.386
hapln1ahyaluronan and proteoglycan link protein 1a0.383
epha7eph receptor A70.376
hoxb10ahomeo box B10a0.364
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.364
hhiphedgehog interacting protein0.362
wif1wnt inhibitory factor 10.355
ptmabprothymosin, alpha b0.350
fzd10frizzled homolog 100.349
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.349
cdx4caudal type homeo box transcription factor 40.348
hoxc6ahomeo box C6a0.344
kif17kinesin family member 170.334
neurodneurogenic differentiation0.334
foxj1aforkhead box J1a0.332
mab21l2mab-21-like 20.331
sox2SRY-box containing gene 20.321
wnt3wingless-type MMTV integration site family, member 30.318
phox2apaired-like homeobox 2a0.315
cldn8claudin 80.315
cx27.5connexin 27.50.314
hmx4H6 family homeobox 40.312
pcsk1proprotein convertase subtilisin/kexin type 10.310
pcsk7proprotein convertase subtilisin/kexin type 70.305
pcsk2proprotein convertase subtilisin/kexin type 20.298
jag1bjagged 1b0.297
ptf1apancreas specific transcription factor, 1a0.291
hoxb3ahomeo box B3a0.287
ptgs1prostaglandin-endoperoxide synthase 10.286
dladeltaA0.282
ddcdopa decarboxylase0.281
wnt1wingless-type MMTV integration site family, member 10.281
fabp11afatty acid binding protein 11a0.279
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism