The network for 'pallium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pallium development

The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Gli3GLI-Kruppel family member GLI31.000
Pax6paired box gene 61.000
Pax2paired box gene 21.000
Ctnnb1catenin (cadherin associated protein), beta 11.000
Sox2SRY-box containing gene 21.000
Gli2GLI-Kruppel family member GLI21.000
Pax3paired box gene 30.999
Foxc1forkhead box C10.999
Fgfr2fibroblast growth factor receptor 20.999
Emx1empty spiracles homolog 1 (Drosophila)0.999
Foxg1forkhead box G10.997
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.995
Dlx5distal-less homeobox 50.995
Msx1homeobox, msh-like 10.994
Hand1heart and neural crest derivatives expressed transcript 10.994
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.993
Tcfap2atranscription factor AP-2, alpha0.993
Fgfr1fibroblast growth factor receptor 10.990
Hand2heart and neural crest derivatives expressed transcript 20.987
Nognoggin0.987
Dab1disabled homolog 1 (Drosophila)0.985
Rargretinoic acid receptor, gamma0.985
Trp53transformation related protein 530.985
Prrx1paired related homeobox 10.984
Eya1eyes absent 1 homolog (Drosophila)0.984
Insm1insulinoma-associated 10.983
Sox9SRY-box containing gene 90.982
Emx2empty spiracles homolog 2 (Drosophila)0.980
Ascl1achaete-scute complex homolog 1 (Drosophila)0.979
Foxc2forkhead box C20.978
Fgf10fibroblast growth factor 100.978
Bmp4bone morphogenetic protein 40.978
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.974
Efnb2ephrin B20.973
Col2a1collagen, type II, alpha 10.972
Pbx1pre B-cell leukemia transcription factor 10.967
Leprleptin receptor0.967
Lhx1LIM homeobox protein 10.964
Pou3f3POU domain, class 3, transcription factor 30.961
Epha4Eph receptor A40.960
Tgfb2transforming growth factor, beta 20.959
Zeb1zinc finger E-box binding homeobox 10.957
Fgf8fibroblast growth factor 80.956
Nkx2-1NK2 homeobox 10.954
Hoxa1homeobox A10.953
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.953
Trp63transformation related protein 630.952
Msx2homeobox, msh-like 20.951
Neurod1neurogenic differentiation 10.948
Myod1myogenic differentiation 10.945
Ntf3neurotrophin 30.944
Bmp7bone morphogenetic protein 70.944
Hes1hairy and enhancer of split 1 (Drosophila)0.941
Pax8paired box gene 80.941
Lmx1aLIM homeobox transcription factor 1 alpha0.935
Bcl2B-cell leukemia/lymphoma 20.934
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.933
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.933
Retret proto-oncogene0.931
Pitx2paired-like homeodomain transcription factor 20.926
Apcadenomatosis polyposis coli0.920
Hoxd13homeobox D130.917
Pitx1paired-like homeodomain transcription factor 10.915
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.915
Id1inhibitor of DNA binding 10.914
Chd7chromodomain helicase DNA binding protein 70.913
Pou4f3POU domain, class 4, transcription factor 30.912
Alx4aristaless-like homeobox 40.910
Tbx1T-box 10.899
Tbx3T-box 30.891
Ptpn11protein tyrosine phosphatase, non-receptor type 110.887
Gdnfglial cell line derived neurotrophic factor0.883
Sox3SRY-box containing gene 30.880
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.876
Gbx2gastrulation brain homeobox 20.872
Dccdeleted in colorectal carcinoma0.870
Ror2receptor tyrosine kinase-like orphan receptor 20.866
Dkk1dickkopf homolog 1 (Xenopus laevis)0.862
En1engrailed 10.854
Nrp1neuropilin 10.852
Pthlhparathyroid hormone-like peptide0.850
Sox11SRY-box containing gene 110.850
Hoxa2homeobox A20.842
Phox2bpaired-like homeobox 2b0.837
Smad3MAD homolog 3 (Drosophila)0.835
Prrx2paired related homeobox 20.833
Gscgoosecoid homeobox0.832
Hoxd11homeobox D110.816
Chrdchordin0.813
Notch1Notch gene homolog 1 (Drosophila)0.806
Gata4GATA binding protein 40.805
Wnt6wingless-related MMTV integration site 60.804
Rxraretinoid X receptor alpha0.802
Rarbretinoic acid receptor, beta0.800
Hoxb1homeobox B10.799
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.796
Bdnfbrain derived neurotrophic factor0.794
Bbs4Bardet-Biedl syndrome 4 (human)0.794
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PEX14peroxisomal biogenesis factor 140.752
GSK3Bglycogen synthase kinase 3 beta0.728
MAP3K5mitogen-activated protein kinase kinase kinase 50.631
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.485
CASP9caspase 9, apoptosis-related cysteine peptidase0.450
LAMC1laminin, gamma 1 (formerly LAMB2)0.421
LAMB1laminin, beta 10.413
SORBS3sorbin and SH3 domain containing 30.413
VEGFAvascular endothelial growth factor A0.364
DLG4discs, large homolog 4 (Drosophila)0.354
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.330
PEX19peroxisomal biogenesis factor 190.305
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.204
NEDD4neural precursor cell expressed, developmentally down-regulated 40.184
BAK1BCL2-antagonist/killer 10.180
PEX12peroxisomal biogenesis factor 120.168
AXIN1axin 10.140
BCL2L1BCL2-like 10.139
TCF4transcription factor 40.139
TSC2tuberous sclerosis 20.123
USP46ubiquitin specific peptidase 460.119
E2F1E2F transcription factor 10.108
SCHIP1schwannomin interacting protein 10.107
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.107
PAX3paired box 30.095
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.092
ARandrogen receptor0.087
HNF4Ahepatocyte nuclear factor 4, alpha0.081
NR4A1nuclear receptor subfamily 4, group A, member 10.078
SOX10SRY (sex determining region Y)-box 100.078
PAX6paired box 60.076
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.076
ZHX1zinc fingers and homeoboxes 10.076
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.074
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.072
WDR20WD repeat domain 200.067
SPTBN4spectrin, beta, non-erythrocytic 40.064
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.062
MKL1megakaryoblastic leukemia (translocation) 10.061
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.061
APPamyloid beta (A4) precursor protein0.060
UBR1ubiquitin protein ligase E3 component n-recognin 10.057
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.055
MAP1Amicrotubule-associated protein 1A0.048
TP73tumor protein p730.047
SIX3SIX homeobox 30.047
EZRezrin0.044
CDC27cell division cycle 27 homolog (S. cerevisiae)0.043
NR4A2nuclear receptor subfamily 4, group A, member 20.042
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.041
RXRAretinoid X receptor, alpha0.041
UBE3Aubiquitin protein ligase E3A0.040
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.040
ESR1estrogen receptor 10.038
CPEcarboxypeptidase E0.035
TMEM173transmembrane protein 1730.034
GATAD2BGATA zinc finger domain containing 2B0.033
TP53tumor protein p530.033
APCadenomatous polyposis coli0.033
SNAPINSNAP-associated protein0.032
EPAS1endothelial PAS domain protein 10.029
PAX8paired box 80.029
XIAPX-linked inhibitor of apoptosis0.029
RPL18Aribosomal protein L18a0.029
NCOR2nuclear receptor corepressor 20.028
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.028
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.028
PCM1pericentriolar material 10.028
AKT1v-akt murine thymoma viral oncogene homolog 10.027
ASB7ankyrin repeat and SOCS box containing 70.027
COL4A3BPcollagen, type IV, alpha 3 (Goodpasture antigen) binding protein0.027
SKIv-ski sarcoma viral oncogene homolog (avian)0.027
QKIquaking homolog, KH domain RNA binding (mouse)0.026
SCRIBscribbled homolog (Drosophila)0.026
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.026
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.025
SNX27sorting nexin family member 270.024
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.024
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.023
LHX2LIM homeobox 20.023
BBS2Bardet-Biedl syndrome 20.022
IGF1Rinsulin-like growth factor 1 receptor0.022
LIG3ligase III, DNA, ATP-dependent0.022
BTRCbeta-transducin repeat containing0.021
PSEN2presenilin 2 (Alzheimer disease 4)0.021
RDXradixin0.021
TTC8tetratricopeptide repeat domain 80.021
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.020
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.019
FLNBfilamin B, beta0.019
YAP1Yes-associated protein 10.019
COL5A2collagen, type V, alpha 20.018
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.018
DCTN1dynactin 10.018
BAI1brain-specific angiogenesis inhibitor 10.017
ALKanaplastic lymphoma receptor tyrosine kinase0.017
SLIT2slit homolog 2 (Drosophila)0.017
PKP4plakophilin 40.017
RTKNrhotekin0.017
MED25mediator complex subunit 250.017
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa2annexin A20.189
Lrrc7leucine rich repeat containing 70.134
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.113
Adra2cadrenergic, alpha-2C-, receptor0.105
Dlg4discs, large homolog 4 (Drosophila)0.097
DbpD site of albumin promoter (albumin D-box) binding protein0.093
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.082
Cckbrcholecystokinin B receptor0.080
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.078
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.073
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.072
RorbRAR-related orphan receptor B0.066
Nr5a2nuclear receptor subfamily 5, group A, member 20.059
Akap5A kinase (PRKA) anchor protein 50.056
Ednrbendothelin receptor type B0.055
Lgals3lectin, galactoside-binding, soluble, 30.054
Tlr4toll-like receptor 40.054
Nkx6-1NK6 homeobox 10.052
Nrxn3neurexin 30.052
Cd40lgCD40 ligand0.050
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.049
Neurod2neurogenic differentiation 20.047
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.047
Aqp4aquaporin 40.047
Cpb1carboxypeptidase B1 (tissue)0.046
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.046
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.046
Dlgap1discs, large (Drosophila) homolog-associated protein 10.044
Lin7blin-7 homolog b (C. elegans)0.043
Il12binterleukin 12B0.042
Nr4a2nuclear receptor subfamily 4, group A, member 20.042
Casp3caspase 30.042
Glp1rglucagon-like peptide 1 receptor0.041
Gad2glutamate decarboxylase 20.040
Pou3f3POU class 3 homeobox 30.040
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.039
Pank2pantothenate kinase 2 (Hallervorden-Spatz syndrome)0.038
Grik1glutamate receptor, ionotropic, kainate 10.038
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.037
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.037
Gfra2GDNF family receptor alpha 20.036
Znf536zinc finger protein 5360.036
Cd9CD9 molecule0.035
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.034
Olr1493olfactory receptor gene Olr14930.034
Gria4glutamate receptor, ionotrophic, AMPA 40.034
Pdcphosducin0.033
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.033
Cmklr1chemokine-like receptor 10.033
Hist1h2bahistone cluster 1, H2ba0.033
Crygacrystallin, gamma A0.033
S100a11S100 calcium binding protein A11 (calizzarin)0.033
Rup2urinary protein 20.033
Itpr2inositol 1,4,5-triphosphate receptor, type 20.032
Nr4a1nuclear receptor subfamily 4, group A, member 10.031
Unc13aunc-13 homolog A (C. elegans)0.031
Hoxa2homeo box A20.031
Map2microtubule-associated protein 20.031
Anxa1annexin A10.031
Tnrtenascin R0.031
Il10rainterleukin 10 receptor, alpha0.031
Il15interleukin 150.030
Egr3early growth response 30.030
Grm1glutamate receptor, metabotropic 10.030
S100a10S100 calcium binding protein A100.030
Sult1d1sulfotransferase family 1D, member 10.030
Csf1colony stimulating factor 1 (macrophage)0.029
Pou2f2POU class 2 homeobox 20.029
Gria2glutamate receptor, ionotropic, AMPA 20.029
Casp12caspase 120.028
Actr2ARP2 actin-related protein 2 homolog (yeast)0.028
Fgfr2fibroblast growth factor receptor 20.028
Adam17ADAM metallopeptidase domain 170.027
Gng7guanine nucleotide binding protein (G protein), gamma 70.027
Trim9tripartite motif-containing 90.027
Bcl2B-cell CLL/lymphoma 20.027
Rims1regulating synaptic membrane exocytosis 10.027
Ahraryl hydrocarbon receptor0.027
Ptch1patched homolog 1 (Drosophila)0.027
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.026
Arandrogen receptor0.026
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.026
CamkvCaM kinase-like vesicle-associated0.026
Lzts1leucine zipper, putative tumor suppressor 10.026
Gria1glutamate receptor, ionotropic, AMPA 10.026
Grid2glutamate receptor, ionotropic, delta 20.026
Slc12a1solute carrier family 12 (sodium/potassium/chloride transporters), member 10.025
Crhbpcorticotropin releasing hormone binding protein0.025
Adam7ADAM metallopeptidase domain 70.025
Unc5aunc-5 homolog A (C. elegans)0.025
Npy5rneuropeptide Y receptor Y50.025
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.025
Calcrlcalcitonin receptor-like0.024
Tgfbr2transforming growth factor, beta receptor II0.024
Robo2roundabout homolog 2 (Drosophila)0.024
Jak2Janus kinase 20.024
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.024
Znf532zinc finger protein 5320.023
Vcsa1variable coding sequence A10.023
LOC246267resection-induced TPI (rs11)0.023
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism